#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35324	uniprotkb:Q8BHK6	intact:EBI-8022357|uniprotkb:Q8C268|intact:MINT-5312801	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	psi-mi:sh21b_mouse(display_long)|uniprotkb:Eat2a(gene name synonym)|uniprotkb:Sh2d1b(gene name)|psi-mi:Sh2d1b(display_short)|uniprotkb:Eat2(gene name synonym)|uniprotkb:Sh2d1b1(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463822|imex:IM-24861-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1I3Z|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	-	comment:mint|function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells	-	figure legend:5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bi-141)|taxid:10090(mouse BI-141 T cell  hybridoma lacking CRACC, EAT-2 and SAP)	-	2015/12/09	2015/12/09	rogid:bRcxf2nKJ12OloTApJ64J3h9U6810090	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rigid:puxK8ASvsbwYmAAlP1FAuIX5nU0	false	-	sufficient binding region:1-249..249	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QUM4	uniprotkb:O88890	intact:EBI-7910086|intact:MINT-205762|uniprotkb:Q9QXZ3|ensembl:ENSMUSP00000015460	intact:EBI-7910438|intact:MINT-205896|uniprotkb:A2ANL8|uniprotkb:Q9QWV6|ensembl:ENSMUSP00000005839|ensembl:ENSMUSP00000141070	psi-mi:slaf1_mouse(display_long)|uniprotkb:SLAM family member 1(gene name synonym)|uniprotkb:Slam(gene name synonym)|uniprotkb:Slamf1(gene name)|psi-mi:Slamf1(display_short)	psi-mi:sh21a_mouse(display_long)|uniprotkb:Sh2d1a(gene name)|psi-mi:Sh2d1a(display_short)|uniprotkb:Xlp(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule-associated protein(gene name synonym)|uniprotkb:T-cell signal transduction molecule SAP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463842|imex:IM-24861-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038758.2|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010407(Signaling lymphocytic activation molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9QUM4|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|ensembl:ENSMUSG00000015316(gene)|ensembl:ENSMUST00000015460(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001787"(natural killer cell proliferation)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0009897"(external side of plasma membrane)	refseq:NP_001300617.1|refseq:NP_001300618.1|refseq:NP_001300620.1|refseq:NP_035494.1|ensembl:ENSMUSG00000005696(gene)|ensembl:ENSMUST00000005839(transcript)|ensembl:ENSMUST00000189753(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0006959"(humoral immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR017289(SH2 protein 1A)|interpro:IPR035876|interpro:IPR036860|mint:O88890|reactome:R-MMU-198933	-	function:"High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates"|comment:mint	function:Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the slam cytoplasmic region|comment:mint	figure legend:5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bi-141)|taxid:10090(mouse BI-141 T cell  hybridoma lacking CRACC, EAT-2 and SAP)	-	2015/12/09	2015/12/09	rogid:yppESR3UEtf7xYxgnHNpGsRrwBw10090	rogid:VdVOCdnlVE4kM2Ecdk0+guAXki410090	rigid:4RMspRqqwpWRxhFQe7p/ZxCxSlw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35324	uniprotkb:Q8BHK6	intact:EBI-8022357|uniprotkb:Q8C268|intact:MINT-5312801	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	psi-mi:sh21b_mouse(display_long)|uniprotkb:Eat2a(gene name synonym)|uniprotkb:Sh2d1b(gene name)|psi-mi:Sh2d1b(display_short)|uniprotkb:Eat2(gene name synonym)|uniprotkb:Sh2d1b1(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463879|imex:IM-24861-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1I3Z|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	-	comment:mint|function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells|comment:A Sh2d1b/EAT-2 mutant construct with tyr120phe and tyr127phe also interacts	comment:SLAMF7/CRACC mutants tyr282phe and tyr287phe also interact	figure legend:7a and d|agonist:"FYN lacking SH2 domain (mouse Fyn construct co-transfected)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2015/12/09	2015/12/09	rogid:bRcxf2nKJ12OloTApJ64J3h9U6810090	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rigid:puxK8ASvsbwYmAAlP1FAuIX5nU0	false	-	sufficient binding region:1-249..249|mutation disrupting interaction:302-302|mutation disrupting interaction:282-282,287-287,302-302	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35324	uniprotkb:Q8BHK6	intact:EBI-8022357|uniprotkb:Q8C268|intact:MINT-5312801	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	psi-mi:sh21b_mouse(display_long)|uniprotkb:Eat2a(gene name synonym)|uniprotkb:Sh2d1b(gene name)|psi-mi:Sh2d1b(display_short)|uniprotkb:Eat2(gene name synonym)|uniprotkb:Sh2d1b1(gene name synonym)|uniprotkb:EWS/FLI1-activated transcript 2(gene name synonym)	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463901|imex:IM-24861-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1I3Z|interpro:IPR000980(SH2 motif)|interpro:IPR035049|interpro:IPR036860|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	-	comment:mint|function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2015/12/10	rogid:bRcxf2nKJ12OloTApJ64J3h9U6810090	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rigid:puxK8ASvsbwYmAAlP1FAuIX5nU0	false	-	sufficient binding region:296-309|O4'-phospho-L-tyrosine:302-302	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BHK6	uniprotkb:P06241	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463909|imex:IM-24861-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	-	-	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2020/01/07	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rigid:WWmizH4PEoZXMBSTqz/DXggl2GM	false	sufficient binding region:296-309|O4'-phospho-L-tyrosine:302-302	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BHK6	uniprotkb:P41240	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463909|imex:IM-24861-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369	-	-	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2020/01/07	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rigid:WWmizH4PEoZXMBSTqz/DXggl2GM	false	sufficient binding region:296-309|O4'-phospho-L-tyrosine:302-302	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BHK6	uniprotkb:Q92835	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	intact:EBI-1380477|uniprotkb:O00145|uniprotkb:Q13544|uniprotkb:Q13545|uniprotkb:Q6P5A4|uniprotkb:Q92656|uniprotkb:Q9UE80|ensembl:ENSP00000405338|ensembl:ENSP00000487191	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:ship1_human(display_long)|uniprotkb:INPP5D(gene name)|psi-mi:INPP5D(display_short)|uniprotkb:SHIP(gene name synonym)|uniprotkb:SHIP1(gene name synonym)|uniprotkb:Inositol polyphosphate-5-phosphatase of 145 kDa(gene name synonym)|uniprotkb:p150Ship(gene name synonym)|uniprotkb:SH2 domain-containing inositol 5'-phosphatase 1(gene name synonym)|uniprotkb:Inositol polyphosphate-5-phosphatase D(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 5-phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463909|imex:IM-24861-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	refseq:NP_001017915.1|refseq:NP_005532.2|ensembl:ENST00000359570|ensembl:ENSP00000352575|ensembl:ENSP00000405338|ensembl:ENST00000629761|ensembl:ENSP00000486669|ensembl:ENSP00000487191|ensembl:ENSG00000168918(gene)|ensembl:ENSG00000281614(gene)|ensembl:ENST00000445964(transcript)|ensembl:ENST00000630854(transcript)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0016314"(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045659"(negative regulation of neutrophil differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|interpro:IPR036860|mint:Q92835|rcsb pdb:2YSX|rcsb pdb:5RW2|rcsb pdb:5RW3|rcsb pdb:5RW4|rcsb pdb:5RW5|rcsb pdb:5RW6|rcsb pdb:5RW7|rcsb pdb:5RW8|rcsb pdb:5RW9|rcsb pdb:5RWA|rcsb pdb:5RWB|rcsb pdb:5RWC|rcsb pdb:5RWD|rcsb pdb:5RWE|rcsb pdb:5RWF|rcsb pdb:5RWG|rcsb pdb:5RWH|rcsb pdb:5RWI|rcsb pdb:5RWJ|rcsb pdb:5RWK|rcsb pdb:5RWL|rcsb pdb:5RWM|rcsb pdb:5RWN|rcsb pdb:5RWO|rcsb pdb:5RWP|rcsb pdb:5RWQ|rcsb pdb:5RWR|rcsb pdb:5RWS|rcsb pdb:5RWT|rcsb pdb:5RWU|rcsb pdb:5RWV|rcsb pdb:5RWW|rcsb pdb:5RWX|rcsb pdb:5RWY|rcsb pdb:5RWZ|rcsb pdb:5RX0|rcsb pdb:5RX1|rcsb pdb:5RX2|rcsb pdb:5RX3|rcsb pdb:5RX4|rcsb pdb:5RX5|rcsb pdb:5RX6|rcsb pdb:5RX7|rcsb pdb:5RX8|rcsb pdb:5RX9|rcsb pdb:5RXA|rcsb pdb:5RXB|rcsb pdb:5RXC|rcsb pdb:5RXD|rcsb pdb:5RXE|rcsb pdb:5RXF|rcsb pdb:5RXG|rcsb pdb:5RXH|rcsb pdb:5RXI|rcsb pdb:5RXJ|rcsb pdb:5RXK|rcsb pdb:5RXL|rcsb pdb:5RXM|rcsb pdb:5RXO|rcsb pdb:5RXP|rcsb pdb:5RXQ|rcsb pdb:5RXR|rcsb pdb:5RXS|rcsb pdb:5RXT|rcsb pdb:5RXU|rcsb pdb:5RXV|rcsb pdb:5RXW|rcsb pdb:5RXX|rcsb pdb:5RXY|rcsb pdb:5RXZ|rcsb pdb:5RY0|rcsb pdb:5RY1|rcsb pdb:5RY2|rcsb pdb:5RY3|rcsb pdb:5RY4|rcsb pdb:5RY5|rcsb pdb:5RY6|rcsb pdb:5RY7|rcsb pdb:5RY8|rcsb pdb:5RY9|rcsb pdb:5RYA|rcsb pdb:5RYB|rcsb pdb:5RYC|rcsb pdb:5RYD|rcsb pdb:5RYE|rcsb pdb:5RYF|rcsb pdb:5RYG|rcsb pdb:5RYH|rcsb pdb:5RYI|rcsb pdb:5RYJ|rcsb pdb:5RYK|rcsb pdb:5RYL|rcsb pdb:6IBD|rcsb pdb:6XY7|reactome:R-HSA-1660499|reactome:R-HSA-1855204|reactome:R-HSA-202424|reactome:R-HSA-210990|reactome:R-HSA-912526	-	-	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2020/01/07	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rogid:lM4QLD8DUZmagYuz8qoKAZqjJOI9606	rigid:WWmizH4PEoZXMBSTqz/DXggl2GM	false	sufficient binding region:296-309|O4'-phospho-L-tyrosine:302-302	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BHK6	uniprotkb:Q06124	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463909|imex:IM-24861-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N	-	-	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2020/01/07	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	rigid:WWmizH4PEoZXMBSTqz/DXggl2GM	false	sufficient binding region:296-309|O4'-phospho-L-tyrosine:302-302	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BHK6	uniprotkb:P29350	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	intact:EBI-78260|intact:EBI-28977917|ensembl:ENSP00000326010|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463909|imex:IM-24861-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	ensembl:ENSG00000111679(gene)|ensembl:ENST00000318974(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|rcsb pdb:3PS5|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|ensembl:ENSP00000326010|ensembl:ENST00000399448|ensembl:ENSP00000382376|ensembl:ENST00000456013|ensembl:ENSP00000391592|refseq:XP_011519290.1|dip:DIP-31002N	-	-	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2020/01/07	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	rigid:WWmizH4PEoZXMBSTqz/DXggl2GM	false	sufficient binding region:296-309|O4'-phospho-L-tyrosine:302-302	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BHK6	uniprotkb:P06241	intact:EBI-11463802|uniprotkb:Q8BTL2|uniprotkb:Q8CJ63|uniprotkb:Q8CJ64|uniprotkb:Q8CJ65|uniprotkb:Q91XA0	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:slaf7_mouse(display_long)|uniprotkb:Slamf7(gene name)|psi-mi:Slamf7(display_short)|uniprotkb:Leukocyte cell-surface antigen(gene name synonym)|uniprotkb:Novel Ly9(gene name synonym)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cruz-Munoz et al. (2009)	imex:IM-24861|pubmed:19151721	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11463931|imex:IM-24861-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237176.1|refseq:NP_653122.2|refseq:XP_011237177.1|refseq:XP_011237178.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-MMU-198933|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032814"(regulation of natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR036179	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	-	-	-	figure legend:7f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/12/09	2015/12/10	rogid:8a7rBqBJAqqerO0EgTLu3pkZCIw10090	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rigid:Ij16YlKitBuu4KixNL3MOndJS2E	false	sufficient binding region:276-294|O4'-phospho-L-tyrosine:282-282	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)