#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-10919313	uniprotkb:P23874	-	intact:EBI-560590|uniprotkb:P76139|uniprotkb:P76880|uniprotkb:P77507|ensemblbacteria:AAC74580|ensemblbacteria:BAA15179	psi-mi:actatccccttaaggggatag(display_short)|psi-mi:EBI-10919313(display_long)	psi-mi:hipa_ecoli(display_long)|uniprotkb:hipA(gene name)|psi-mi:hipA(display_short)|uniprotkb:b1507(locus name)|uniprotkb:JW1500(locus name)|uniprotkb:Toxin HipA(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10919303|wwpdb:3dnv|imex:IM-24372-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416024.1|refseq:WP_001125439.1|dip:DIP-9898N|ensemblbacteria:AAC74580(transcript)|ensemblbacteria:b1507(gene)|ensemblbacteria:BAA15179(gene)|ensemblbacteria:BAA15179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0022611"(dormancy process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044010"(single-species biofilm formation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR012893(HipA-like, C-terminal)|interpro:IPR017508(HipA, N-terminal)|rcsb pdb:2WIU|rcsb pdb:3DNT|rcsb pdb:3DNU|rcsb pdb:3DNV|rcsb pdb:3FBR|rcsb pdb:3HZI|rcsb pdb:3TPB|rcsb pdb:3TPD|rcsb pdb:3TPE|rcsb pdb:3TPT|rcsb pdb:3TPV|rcsb pdb:4YG7|rcsb pdb:5K98	-	-	-	figure legend:Supp Table 1|3d-r-factors:Rworking  0.228, Rfree 0.285|3d-resolution:2.68A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/23	2015/07/23	-	rogid:FUbaO1OD8dHDXnJhe5BuojBJV9483333	-	false	-	L-selenomethionine:?-?|his tag:n-n|mutation:309-309	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-10919313	uniprotkb:P23873	-	intact:EBI-1129654|ensemblbacteria:AAC74581|ensemblbacteria:BAA15180	psi-mi:actatccccttaaggggatag(display_short)|psi-mi:EBI-10919313(display_long)	psi-mi:hipb_ecoli(display_long)|uniprotkb:hipB(gene name)|psi-mi:hipB(display_short)|uniprotkb:b1508(locus name)|uniprotkb:JW1501(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10919303|wwpdb:3dnv|imex:IM-24372-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416025.1|refseq:WP_001301023.1|ensemblbacteria:AAC74581(transcript)|ensemblbacteria:b1508(gene)|ensemblbacteria:BAA15180(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000985"|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|rcsb pdb:2WIU|rcsb pdb:3DNV|rcsb pdb:3HZI|rcsb pdb:4YG1|ensemblbacteria:BAA15180(transcript)|rcsb pdb:4YG4|rcsb pdb:4YG7|rcsb pdb:4Z58|rcsb pdb:4Z59|rcsb pdb:4Z5C|rcsb pdb:4Z5D|rcsb pdb:4Z5H|rcsb pdb:5K98|dip:DIP-9899N	-	-	-	figure legend:Supp Table 1|3d-r-factors:Rworking  0.228, Rfree 0.285|3d-resolution:2.68A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/23	2015/07/23	-	rogid:Mj88c/zC9TgS83jtpE/fdIpqSW083333	-	false	-	his tag:n-n	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	intact:EBI-10919313	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	-	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:actatccccttaaggggatag(display_short)|psi-mi:EBI-10919313(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10959804|wwpdb:3HZI|imex:IM-24372-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	-	-	-	-	-	figure legend:Supp Table 1|3d-r-factors:Rworking 0.265, Rfree 0.283|3d-resolution:2.98A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/23	2015/08/12	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-10919313	uniprotkb:P23874	-	intact:EBI-560590|uniprotkb:P76139|uniprotkb:P76880|uniprotkb:P77507|ensemblbacteria:AAC74580|ensemblbacteria:BAA15179	psi-mi:actatccccttaaggggatag(display_short)|psi-mi:EBI-10919313(display_long)	psi-mi:hipa_ecoli(display_long)|uniprotkb:hipA(gene name)|psi-mi:hipA(display_short)|uniprotkb:b1507(locus name)|uniprotkb:JW1500(locus name)|uniprotkb:Toxin HipA(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10959804|wwpdb:3HZI|imex:IM-24372-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416024.1|refseq:WP_001125439.1|dip:DIP-9898N|ensemblbacteria:AAC74580(transcript)|ensemblbacteria:b1507(gene)|ensemblbacteria:BAA15179(gene)|ensemblbacteria:BAA15179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0022611"(dormancy process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044010"(single-species biofilm formation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR012893(HipA-like, C-terminal)|interpro:IPR017508(HipA, N-terminal)|rcsb pdb:2WIU|rcsb pdb:3DNT|rcsb pdb:3DNU|rcsb pdb:3DNV|rcsb pdb:3FBR|rcsb pdb:3HZI|rcsb pdb:3TPB|rcsb pdb:3TPD|rcsb pdb:3TPE|rcsb pdb:3TPT|rcsb pdb:3TPV|rcsb pdb:4YG7|rcsb pdb:5K98	-	-	-	figure legend:Supp Table 1|3d-r-factors:Rworking 0.265, Rfree 0.283|3d-resolution:2.98A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/23	2015/08/12	-	rogid:FUbaO1OD8dHDXnJhe5BuojBJV9483333	-	false	-	L-selenomethionine:?-?|his tag:n-n|mutation:309-309	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-10919313	uniprotkb:P23873	-	intact:EBI-1129654|ensemblbacteria:AAC74581|ensemblbacteria:BAA15180	psi-mi:actatccccttaaggggatag(display_short)|psi-mi:EBI-10919313(display_long)	psi-mi:hipb_ecoli(display_long)|uniprotkb:hipB(gene name)|psi-mi:hipB(display_short)|uniprotkb:b1508(locus name)|uniprotkb:JW1501(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10959804|wwpdb:3HZI|imex:IM-24372-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416025.1|refseq:WP_001301023.1|ensemblbacteria:AAC74581(transcript)|ensemblbacteria:b1508(gene)|ensemblbacteria:BAA15180(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000985"|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|rcsb pdb:2WIU|rcsb pdb:3DNV|rcsb pdb:3HZI|rcsb pdb:4YG1|ensemblbacteria:BAA15180(transcript)|rcsb pdb:4YG4|rcsb pdb:4YG7|rcsb pdb:4Z58|rcsb pdb:4Z59|rcsb pdb:4Z5C|rcsb pdb:4Z5D|rcsb pdb:4Z5H|rcsb pdb:5K98|dip:DIP-9899N	-	-	-	figure legend:Supp Table 1|3d-r-factors:Rworking 0.265, Rfree 0.283|3d-resolution:2.98A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/23	2015/08/12	-	rogid:Mj88c/zC9TgS83jtpE/fdIpqSW083333	-	false	-	his tag:n-n	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P23874	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-560590|uniprotkb:P76139|uniprotkb:P76880|uniprotkb:P77507|ensemblbacteria:AAC74580|ensemblbacteria:BAA15179	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hipa_ecoli(display_long)|uniprotkb:hipA(gene name)|psi-mi:hipA(display_short)|uniprotkb:b1507(locus name)|uniprotkb:JW1500(locus name)|uniprotkb:Toxin HipA(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11297227|wwpdb:3DNT|imex:IM-24372-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416024.1|refseq:WP_001125439.1|dip:DIP-9898N|ensemblbacteria:AAC74580(transcript)|ensemblbacteria:b1507(gene)|ensemblbacteria:BAA15179(gene)|ensemblbacteria:BAA15179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0022611"(dormancy process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044010"(single-species biofilm formation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR012893(HipA-like, C-terminal)|interpro:IPR017508(HipA, N-terminal)|rcsb pdb:2WIU|rcsb pdb:3DNT|rcsb pdb:3DNU|rcsb pdb:3DNV|rcsb pdb:3FBR|rcsb pdb:3HZI|rcsb pdb:3TPB|rcsb pdb:3TPD|rcsb pdb:3TPE|rcsb pdb:3TPT|rcsb pdb:3TPV|rcsb pdb:4YG7|rcsb pdb:5K98	-	-	-	figure legend:Supp Table 1|3d-r-factors:Rworking 0.185, Rfree 0.217|3d-resolution:1.66A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/23	2015/10/08	-	rogid:FUbaO1OD8dHDXnJhe5BuojBJV9483333	-	false	-	L-selenomethionine:?-?|his tag:n-n|mutation:309-309	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P23874	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-560590|uniprotkb:P76139|uniprotkb:P76880|uniprotkb:P77507|ensemblbacteria:AAC74580|ensemblbacteria:BAA15179	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hipa_ecoli(display_long)|uniprotkb:hipA(gene name)|psi-mi:hipA(display_short)|uniprotkb:b1507(locus name)|uniprotkb:JW1500(locus name)|uniprotkb:Toxin HipA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10919388|imex:IM-24372-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416024.1|refseq:WP_001125439.1|dip:DIP-9898N|ensemblbacteria:AAC74580(transcript)|ensemblbacteria:b1507(gene)|ensemblbacteria:BAA15179(gene)|ensemblbacteria:BAA15179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0022611"(dormancy process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044010"(single-species biofilm formation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR012893(HipA-like, C-terminal)|interpro:IPR017508(HipA, N-terminal)|rcsb pdb:2WIU|rcsb pdb:3DNT|rcsb pdb:3DNU|rcsb pdb:3DNV|rcsb pdb:3FBR|rcsb pdb:3HZI|rcsb pdb:3TPB|rcsb pdb:3TPD|rcsb pdb:3TPE|rcsb pdb:3TPT|rcsb pdb:3TPV|rcsb pdb:4YG7|rcsb pdb:5K98	-	-	-	figure legend:Supp Figure 2|comment:Atp was added to an existing HIPA-HIPB complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.5x10^-5(molar)	2015/07/23	2015/07/23	-	rogid:FUbaO1OD8dHDXnJhe5BuojBJV9483333	-	false	-	his tag:n-n|mutation:309-309	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P23873	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1129654|ensemblbacteria:AAC74581|ensemblbacteria:BAA15180	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hipb_ecoli(display_long)|uniprotkb:hipB(gene name)|psi-mi:hipB(display_short)|uniprotkb:b1508(locus name)|uniprotkb:JW1501(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10919388|imex:IM-24372-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416025.1|refseq:WP_001301023.1|ensemblbacteria:AAC74581(transcript)|ensemblbacteria:b1508(gene)|ensemblbacteria:BAA15180(gene)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000985"|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|rcsb pdb:2WIU|rcsb pdb:3DNV|rcsb pdb:3HZI|rcsb pdb:4YG1|ensemblbacteria:BAA15180(transcript)|rcsb pdb:4YG4|rcsb pdb:4YG7|rcsb pdb:4Z58|rcsb pdb:4Z59|rcsb pdb:4Z5C|rcsb pdb:4Z5D|rcsb pdb:4Z5H|rcsb pdb:5K98|dip:DIP-9899N	-	-	-	figure legend:Supp Figure 2|comment:Atp was added to an existing HIPA-HIPB complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.5x10^-5(molar)	2015/07/23	2015/07/23	-	rogid:Mj88c/zC9TgS83jtpE/fdIpqSW083333	-	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P23874	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-560590|uniprotkb:P76139|uniprotkb:P76880|uniprotkb:P77507|ensemblbacteria:AAC74580|ensemblbacteria:BAA15179	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hipa_ecoli(display_long)|uniprotkb:hipA(gene name)|psi-mi:hipA(display_short)|uniprotkb:b1507(locus name)|uniprotkb:JW1500(locus name)|uniprotkb:Toxin HipA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Schumacher et al. (2009)	imex:IM-24372|pubmed:19150849	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10919454|imex:IM-24372-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416024.1|refseq:WP_001125439.1|dip:DIP-9898N|ensemblbacteria:AAC74580(transcript)|ensemblbacteria:b1507(gene)|ensemblbacteria:BAA15179(gene)|ensemblbacteria:BAA15179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0022611"(dormancy process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044010"(single-species biofilm formation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR012893(HipA-like, C-terminal)|interpro:IPR017508(HipA, N-terminal)|rcsb pdb:2WIU|rcsb pdb:3DNT|rcsb pdb:3DNU|rcsb pdb:3DNV|rcsb pdb:3FBR|rcsb pdb:3HZI|rcsb pdb:3TPB|rcsb pdb:3TPD|rcsb pdb:3TPE|rcsb pdb:3TPT|rcsb pdb:3TPV|rcsb pdb:4YG7|rcsb pdb:5K98	-	-	-	figure legend:Supp Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:18.0x10^-6(molar)	2015/07/23	2015/07/23	-	rogid:FUbaO1OD8dHDXnJhe5BuojBJV9483333	-	false	-	his tag:n-n|mutation:309-309	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)