#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8VIG1 uniprotkb:Q96MT3 intact:EBI-2312802|uniprotkb:A0JNY8|uniprotkb:Q155C6|uniprotkb:Q3U0W0|uniprotkb:Q4VAD6|uniprotkb:Q9CW43|ensembl:ENSMUSP00000079231|ensembl:ENSMUSP00000109076 intact:EBI-2348662|uniprotkb:Q14C83|uniprotkb:Q71QF8|uniprotkb:Q96N00|ensembl:ENSP00000345064|ensembl:ENSP00000398947|ensembl:ENSP00000401060|ensembl:ENSP00000448359|ensembl:ENSP00000449819|ensembl:ENSP00000491051|ensembl:ENSP00000491228|ensembl:ENSP00000492332|ensembl:ENSP00000492644|ensembl:ENSP00000492763 psi-mi:rest_mouse(display_long)|uniprotkb:Rest(gene name)|psi-mi:Rest(display_short)|uniprotkb:Nrsf(gene name synonym)|uniprotkb:Neural-restrictive silencer factor(gene name synonym) psi-mi:pric1_human(display_long)|uniprotkb:PRICKLE1(gene name)|psi-mi:PRICKLE1(display_short)|uniprotkb:RILP(gene name synonym)|uniprotkb:REST/NRSF-interacting LIM domain protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bassuk et al. (2008) imex:IM-23968|pubmed:18976727 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10684914|imex:IM-23968-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006534905.1|refseq:NP_035393.2|ensembl:ENSMUSG00000029249(gene)|ensembl:ENSMUST00000080359(transcript)|ensembl:ENSMUST00000113449(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2000706"(negative regulation of dense core granule biogenesis)|go:"GO:2000740"(negative regulation of mesenchymal stem cell differentiation)|go:"GO:2000798"(negative regulation of amniotic stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027757|interpro:IPR036236|mint:Q8VIG1|reactome:R-MMU-3214815 refseq:XP_011536248.1|refseq:XP_011536249.1|refseq:NP_001138353.1|refseq:NP_001138354.1|refseq:NP_001138355.1|refseq:NP_694571.2|refseq:XP_016874327.1|refseq:XP_016874328.1|refseq:XP_016874329.1|ensembl:ENSG00000139174(gene)|ensembl:ENST00000345127(transcript)|ensembl:ENST00000445766(transcript)|ensembl:ENST00000455697(transcript)|ensembl:ENST00000548696(transcript)|ensembl:ENST00000552240(transcript)|ensembl:ENST00000639566(transcript)|ensembl:ENST00000639589(transcript)|ensembl:ENST00000639958(transcript)|ensembl:ENST00000640055(transcript)|ensembl:ENST00000640132(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000691"(negative regulation of cardiac muscle cell myoblast differentiation)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033726|interpro:IPR033727|reactome:R-HSA-4608870 omim:612437(see-also) - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/25 2015/02/25 rogid:a2nJenbqqCXCUbKM//5DZQ/hz7I10090 rogid:Ja2xuOriMFG/HYyzg7JuPnFlaOM9606 intact-crc:0526698E51ECFD90|rigid:lsBzX1ERiRnffV0z8JMAM4C1QFw false myc tag:n-n mutation decreasing interaction:104-104|green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8VIG1 uniprotkb:Q96MT3 intact:EBI-2312802|uniprotkb:A0JNY8|uniprotkb:Q155C6|uniprotkb:Q3U0W0|uniprotkb:Q4VAD6|uniprotkb:Q9CW43|ensembl:ENSMUSP00000079231|ensembl:ENSMUSP00000109076 intact:EBI-2348662|uniprotkb:Q14C83|uniprotkb:Q71QF8|uniprotkb:Q96N00|ensembl:ENSP00000345064|ensembl:ENSP00000398947|ensembl:ENSP00000401060|ensembl:ENSP00000448359|ensembl:ENSP00000449819|ensembl:ENSP00000491051|ensembl:ENSP00000491228|ensembl:ENSP00000492332|ensembl:ENSP00000492644|ensembl:ENSP00000492763 psi-mi:rest_mouse(display_long)|uniprotkb:Rest(gene name)|psi-mi:Rest(display_short)|uniprotkb:Nrsf(gene name synonym)|uniprotkb:Neural-restrictive silencer factor(gene name synonym) psi-mi:pric1_human(display_long)|uniprotkb:PRICKLE1(gene name)|psi-mi:PRICKLE1(display_short)|uniprotkb:RILP(gene name synonym)|uniprotkb:REST/NRSF-interacting LIM domain protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bassuk et al. (2008) imex:IM-23968|pubmed:18976727 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10684952|imex:IM-23968-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006534905.1|refseq:NP_035393.2|ensembl:ENSMUSG00000029249(gene)|ensembl:ENSMUST00000080359(transcript)|ensembl:ENSMUST00000113449(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2000706"(negative regulation of dense core granule biogenesis)|go:"GO:2000740"(negative regulation of mesenchymal stem cell differentiation)|go:"GO:2000798"(negative regulation of amniotic stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027757|interpro:IPR036236|mint:Q8VIG1|reactome:R-MMU-3214815 refseq:XP_011536248.1|refseq:XP_011536249.1|refseq:NP_001138353.1|refseq:NP_001138354.1|refseq:NP_001138355.1|refseq:NP_694571.2|refseq:XP_016874327.1|refseq:XP_016874328.1|refseq:XP_016874329.1|ensembl:ENSG00000139174(gene)|ensembl:ENST00000345127(transcript)|ensembl:ENST00000445766(transcript)|ensembl:ENST00000455697(transcript)|ensembl:ENST00000548696(transcript)|ensembl:ENST00000552240(transcript)|ensembl:ENST00000639566(transcript)|ensembl:ENST00000639589(transcript)|ensembl:ENST00000639958(transcript)|ensembl:ENST00000640055(transcript)|ensembl:ENST00000640132(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000691"(negative regulation of cardiac muscle cell myoblast differentiation)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033726|interpro:IPR033727|reactome:R-HSA-4608870 omim:612437(see-also) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/02/25 2015/02/25 rogid:a2nJenbqqCXCUbKM//5DZQ/hz7I10090 rogid:Ja2xuOriMFG/HYyzg7JuPnFlaOM9606 intact-crc:52F24C92BDA9BAB8|rigid:lsBzX1ERiRnffV0z8JMAM4C1QFw false myc tag:n-n green fluorescent protein tag:c-c|mutation decreasing interaction:104-104 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)