#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51151 uniprotkb:Q8IWE5 intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777 intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956|intact:EBI-11039943|uniprotkb:Q5VVD7 psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym) psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765389|imex:IM-9657-1|dip:DIP-88402E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019 ensembl:ENST00000375793|ensembl:ENSP00000364950|ensembl:ENSP00000364956|refseq:NP_055979.2|refseq:XP_005245847.1|ensembl:ENSG00000116786(gene)|ensembl:ENST00000375799(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|dip:DIP-46410N psi-mi:"MI:0465"(dip) - - figure legend:1A, 1C, 3A-D|comment:RAB9A was pre-loaded with guanosine 5'-[gamma-thio]triphosphate|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:7.0x10^-6(molar) 2015/04/02 2017/06/30 rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606 rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606 intact-crc:779C358AF2D643AA|rigid:AKkqxfO0iXEeVeAtQsOqrbuom7g false glutathione s tranferase tag:?-?|mutation:66-66 binding-associated region:762-885 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q56061 uniprotkb:Q8IWE5 intact:EBI-10765408|ensemblbacteria:AAL20153 intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956|intact:EBI-11039943|uniprotkb:Q5VVD7 psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short) psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765402|imex:IM-9657-3|dip:DIP-88403E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_001520468.1|refseq:NP_460194.1|ensemblbacteria:AAL20153(transcript)|ensemblbacteria:STM1224(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032880"(regulation of protein localization)|interpro:IPR010637(Sif)|rcsb pdb:3CXB|rcsb pdb:3HW2|dip:DIP-46411N ensembl:ENST00000375793|ensembl:ENSP00000364950|ensembl:ENSP00000364956|refseq:NP_055979.2|refseq:XP_005245847.1|ensembl:ENSG00000116786(gene)|ensembl:ENST00000375799(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|dip:DIP-46410N psi-mi:"MI:0465"(dip) crc64:83C6185148A774B9 - figure legend:1A, 2D, 3A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.0x10^-7(molar) 2015/04/02 2017/06/30 rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287 rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606 intact-crc:F3D74B1C1127B29B|rigid:Lz4XVeGH3GXbQCi5yjJxJeu9KVw false glutathione s tranferase tag:?-?|mutation decreasing interaction:201-201,197-197 binding-associated region:762-885 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P51149 uniprotkb:Q96NA2 intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486 intact:EBI-2856119|uniprotkb:B2RBQ8|uniprotkb:Q9BSL3|uniprotkb:Q71RE6|uniprotkb:Q9BYS3|ensembl:ENSP00000301336|ensembl:ENSP00000481849 psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym) psi-mi:rilp_human(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-10765426|imex:IM-9657-2|dip:DIP-88404E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N refseq:NP_113618.2|dip:DIP-29458N|ensembl:ENSG00000167705(gene)|ensembl:ENSG00000274145(gene)|ensembl:ENST00000301336(transcript)|ensembl:ENST00000622136(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070676"(intralumenal vesicle formation)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:1YHN|reactome:R-HSA-2132295 psi-mi:"MI:0465"(dip) - crc64:1057A1DAC2FFED94 figure legend:1B|comment:RAB7A was pre-loaded with guanosine 5'-[gamma-thio]triphosphate|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/04/02 2017/06/30 rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606 rogid:dBBOnpVleCSq8//uqicphTGykw09606 intact-crc:1DD3B5CA16B26440|rigid:bOemPPKVC03nPkSIOUw5kj4b2B0 false glutathione s tranferase tag:?-?|mutation:67-67 sufficient binding region:241-320 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P51151 uniprotkb:Q56061 intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777 intact:EBI-10765408|ensemblbacteria:AAL20153 psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym) psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:99287(salty)|taxid:99287(Salmonella typhimurium) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765455|imex:IM-9657-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019 refseq:WP_001520468.1|refseq:NP_460194.1|ensemblbacteria:AAL20153(transcript)|ensemblbacteria:STM1224(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032880"(regulation of protein localization)|interpro:IPR010637(Sif)|rcsb pdb:3CXB|rcsb pdb:3HW2|dip:DIP-46411N - - crc64:83C6185148A774B9 figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/04/02 2017/06/30 rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606 rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287 intact-crc:94B23F215C171C42|rigid:w7LJbCffEE8JeAg32m5M6f33pjI false glutathione s tranferase tag:?-?|mutation:66-66 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P51151 uniprotkb:Q8IWE5 intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777 intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956|intact:EBI-11039943|uniprotkb:Q5VVD7 psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym) psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765455|imex:IM-9657-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019 ensembl:ENST00000375793|ensembl:ENSP00000364950|ensembl:ENSP00000364956|refseq:NP_055979.2|refseq:XP_005245847.1|ensembl:ENSG00000116786(gene)|ensembl:ENST00000375799(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|dip:DIP-46410N - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/04/02 2017/06/30 rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606 rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606 intact-crc:94B23F215C171C42|rigid:w7LJbCffEE8JeAg32m5M6f33pjI false glutathione s tranferase tag:?-?|mutation:66-66 binding-associated region:762-885 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8IWE5 uniprotkb:P51151 intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956|intact:EBI-11039943|uniprotkb:Q5VVD7 intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777 psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short) psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765444|imex:IM-9657-4|dip:DIP-88402E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000375793|ensembl:ENSP00000364950|ensembl:ENSP00000364956|refseq:NP_055979.2|refseq:XP_005245847.1|ensembl:ENSG00000116786(gene)|ensembl:ENST00000375799(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|dip:DIP-46410N refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019 psi-mi:"MI:0465"(dip) - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/04/02 2017/06/30 rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606 rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606 intact-crc:AFE86FC24C64A45E|rigid:AKkqxfO0iXEeVeAtQsOqrbuom7g false glutathione s tranferase tag:?-?|binding-associated region:762-885 green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IWE5 uniprotkb:Q56061 intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956|intact:EBI-11039943|uniprotkb:Q5VVD7 intact:EBI-10765408|ensemblbacteria:AAL20153 psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short) psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:99287(salty)|taxid:99287(Salmonella typhimurium) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765471|imex:IM-9657-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000375793|ensembl:ENSP00000364950|ensembl:ENSP00000364956|refseq:NP_055979.2|refseq:XP_005245847.1|ensembl:ENSG00000116786(gene)|ensembl:ENST00000375799(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|dip:DIP-46410N refseq:WP_001520468.1|refseq:NP_460194.1|ensemblbacteria:AAL20153(transcript)|ensemblbacteria:STM1224(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032880"(regulation of protein localization)|interpro:IPR010637(Sif)|rcsb pdb:3CXB|rcsb pdb:3HW2|dip:DIP-46411N - - crc64:83C6185148A774B9 figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/04/02 2017/06/30 rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606 rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287 intact-crc:C6A14CEE2696808C|rigid:w7LJbCffEE8JeAg32m5M6f33pjI false glutathione s tranferase tag:?-?|binding-associated region:762-885 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IWE5 uniprotkb:P51151 intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956|intact:EBI-11039943|uniprotkb:Q5VVD7 intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777 psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short) psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym) psi-mi:"MI:0096"(pull down) Jackson et al. (2008) pubmed:18787122|imex:IM-9657 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-10765471|imex:IM-9657-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000375793|ensembl:ENSP00000364950|ensembl:ENSP00000364956|refseq:NP_055979.2|refseq:XP_005245847.1|ensembl:ENSG00000116786(gene)|ensembl:ENST00000375799(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|dip:DIP-46410N refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019 - - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/04/02 2017/06/30 rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606 rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606 intact-crc:C6A14CEE2696808C|rigid:w7LJbCffEE8JeAg32m5M6f33pjI false glutathione s tranferase tag:?-?|binding-associated region:762-885 green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)