#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P13224	uniprotkb:P13224	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:"MI:0370"(tox-r dimerization assay)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891084|imex:IM-24276-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2015/06/18	2015/06/18	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rigid:/7Qw8qhnZJD9C5heMXNjytHYosM	false	sufficient binding region:149-168|maltose binding protein tag:c-c|tag:n-n	sufficient binding region:149-168|maltose binding protein tag:c-c|tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02724-PRO_0000012134	uniprotkb:P02724-PRO_0000012134	intact:EBI-11424273	intact:EBI-11424273	psi-mi:p02724-pro_0000012134(display_long)|uniprotkb:GYPA(gene name)|psi-mi:GYPA(display_short)|uniprotkb:GPA(gene name synonym)|uniprotkb:MN sialoglycoprotein(gene name synonym)|uniprotkb:PAS-2(gene name synonym)|uniprotkb:Sialoglycoprotein alpha(gene name synonym)	psi-mi:p02724-pro_0000012134(display_long)|uniprotkb:GYPA(gene name)|psi-mi:GYPA(display_short)|uniprotkb:GPA(gene name synonym)|uniprotkb:MN sialoglycoprotein(gene name synonym)|uniprotkb:PAS-2(gene name synonym)|uniprotkb:Sialoglycoprotein alpha(gene name synonym)	psi-mi:"MI:0370"(tox-r dimerization assay)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891157|imex:IM-24276-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-702665(chain-parent)	intact:EBI-702665(chain-parent)	-	chain-seq-start:20|chain-seq-end:150	chain-seq-start:20|chain-seq-end:150	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2015/06/18	2015/11/25	rogid:jYXvP3epYf9EiC6ZT4Y7cNk2KiA9606	rogid:jYXvP3epYf9EiC6ZT4Y7cNk2KiA9606	rigid:36PHLodVa1KiwDMjxDy6/wlkb/k	false	sufficient binding region:73..73-95..95|tag:n-n|maltose binding protein tag:c-c|mutation disrupting interaction strength:83-83	sufficient binding region:73..73-95..95|tag:n-n|maltose binding protein tag:c-c|mutation disrupting interaction strength:83-83	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13224	uniprotkb:P13224	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891201|imex:IM-24276-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/06/18	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rigid:/7Qw8qhnZJD9C5heMXNjytHYosM	false	mutation:141-145|mutation:173-173|sufficient binding region:141-206	mutation:141-145|mutation:173-173|sufficient binding region:141-206	2	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P13224	uniprotkb:P07359	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:"MI:0227"(reverse phase chromatography)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891245|imex:IM-24276-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	-	-	-	figure legend:Fig. 4|comment:Two disulphide bridges form between the alpha and beta peptides|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/06/18	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rigid:WEmFmFqhyw6cDbggObQwPAqZrok	false	mutation:141-145|mutation:173-173|sufficient binding region:141-206	sufficient binding region:513-584|mutation:513-513	2	1	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P07359	uniprotkb:P13224	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:"MI:0227"(reverse phase chromatography)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891260|imex:IM-24276-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	-	-	-	figure legend:Fig. 4|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/06/18	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	sufficient binding region:513-584|mutation:513-513	mutation:141-145|mutation:173-173|sufficient binding region:141-206	1	2	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P07359	uniprotkb:P14770	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym)	psi-mi:"MI:0227"(reverse phase chromatography)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891260|imex:IM-24276-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1	-	-	-	figure legend:Fig. 4|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/06/18	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	sufficient binding region:513-584|mutation:513-513	sufficient binding region:142-177|mutation:142-143|mutation:170-170	1	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P07359	uniprotkb:P13224	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891291|imex:IM-24276-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	-	-	-	figure legend:Fig. 8B, 8C|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/11/25	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	his tag:n-n|cy3 label:n-n|sufficient binding region:513-559|mutation:513-513	mutation:141-145|mutation:173-173|sufficient binding region:141-206	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07359	uniprotkb:P14770	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891291|imex:IM-24276-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1	-	-	-	figure legend:Fig. 8B, 8C|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/11/25	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	his tag:n-n|cy3 label:n-n|sufficient binding region:513-559|mutation:513-513	cy5 label:170-170|sufficient binding region:142-177|mutation:142-143|mutation:170-170	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07359	uniprotkb:P13224	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891322|imex:IM-24276-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:NP_000398.1|ensembl:ENSG00000203618(gene)|ensembl:ENST00000366425(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030168"(platelet activation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221	-	-	-	figure legend:Fig. 8B|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/11/25	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	his tag:n-n|cy3 label:n-n|sufficient binding region:513-559|mutation:513-513	mutation:141-145|mutation:173-173|sufficient binding region:141-206	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07359	uniprotkb:P14770	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891322|imex:IM-24276-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1	-	-	-	figure legend:Fig. 8B|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/11/25	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	his tag:n-n|cy3 label:n-n|sufficient binding region:513-559|mutation:513-513	cy5 label:170-170|sufficient binding region:142-177|mutation:142-143|mutation:170-170	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07359	uniprotkb:P14770	intact:EBI-297082|ensembl:ENSP00000329380|uniprotkb:Q14441|uniprotkb:Q16469|uniprotkb:Q8N1F3|uniprotkb:Q8NG39|uniprotkb:Q9HDC7|uniprotkb:Q9UEK1|uniprotkb:Q9UQS4|intact:EBI-6595051|uniprotkb:E7ES66	intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942	psi-mi:gp1ba_human(display_long)|uniprotkb:GP1BA(gene name)|psi-mi:GP1BA(display_short)|uniprotkb:Antigen CD42b-alpha(gene name synonym)	psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Luo et al. (2008)	pubmed:18674540|imex:IM-24276	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10891322|imex:IM-24276-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185245(gene)|ensembl:ENST00000329125(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0042730"(fibrinolysis)|interpro:IPR032675|mint:P07359|rcsb pdb:1GWB|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1K13|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1M0Z|rcsb pdb:1M10|rcsb pdb:1OOK|rcsb pdb:1P8V|rcsb pdb:1P9A|rcsb pdb:1QYY|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:2BP3|rcsb pdb:3P72|rcsb pdb:3PMH|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4MGX|rcsb pdb:4YR6|rcsb pdb:6XFQ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-8936459|refseq:NP_000164.5	refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1	-	-	-	figure legend:Fig. 8B|comment:Two disulphide bridges form between the alpha and beta peptides. Addition of IX-TM significantly facilitated formation of native-like disulfide bonds between alpha and beta peptides in detergent micelles|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/06/18	2015/11/25	rogid:aiQSNvhZ96a32v89D3KMptd64589606	rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606	rigid:ZP21ITDznC6zA9iPiMY2cMclljk	false	his tag:n-n|cy3 label:n-n|sufficient binding region:513-559|mutation:513-513	sufficient binding region:142-177|mutation:142-143|mutation:170-170	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)