#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15646	uniprotkb:Q06106	intact:EBI-6838|uniprotkb:P89890|uniprotkb:D6VRX5|ensemblfungi:YDL014W	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	psi-mi:fbrl_yeast(display_long)|uniprotkb:NOP1(gene name)|psi-mi:NOP1(display_short)|uniprotkb:LOT3(gene name synonym)|uniprotkb:YDL014W(locus name)|uniprotkb:D2870(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein NOP1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:"MI:0416"(fluorescence microscopy)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900079|imex:IM-24454-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010270.1|sgd:S000002172|mint:P15646|dip:DIP-698N|ensemblfungi:YDL014W(gene)|ensemblfungi:YDL014W_mRNA(transcript)|go:"GO:0000451"(rRNA 2'-O-methylation)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006364"(rRNA processing)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	go:"GO:0005634"(nucleus)	crc64:56A8B958A7B6066E	-	figure legend:Fig2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2015/07/10	rogid:zc81RbHf8PxId/8oPXPD3/MpmBU559292	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	rigid:P3JxCogyJASMuTDSIGXbJQrDL7M	false	fluorescent protein tag:n-n	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
intact:EBI-10821555	uniprotkb:Q06106	rnacentral:URS00004BEF81_559292	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	psi-mi:rrna 35s yeast(display_short)|psi-mi:EBI-10821555(display_long)	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:"MI:0027"(cosedimentation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900219|imex:IM-24454-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0608"(ribosomal rna)	psi-mi:"MI:0326"(protein)	sgd:S000006486(see-also)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	-	-	figure legend:Fig2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2015/07/15	-	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	-	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
intact:EBI-10821792	intact:EBI-10821812	rnacentral:URS0000444F9B_559292	rnacentral:URS0000182FAB_559292	psi-mi:snru3a yeast(display_short)|psi-mi:EBI-10821792(display_long)	psi-mi:snru14 yeast(display_short)|psi-mi:EBI-10821812(display_long)	psi-mi:"MI:0027"(cosedimentation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900270|imex:IM-24454-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0609"(small nucleolar rna)	-	-	-	-	-	figure legend:Fig6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/04/06	-	-	-	false	-	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q06106	uniprotkb:Q12499	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	intact:EBI-12126|uniprotkb:D6W309|ensemblfungi:YOR310C	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:nop58_yeast(display_long)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOP5(gene name synonym)|uniprotkb:YOR310C(locus name)|uniprotkb:O6108(orf name)	psi-mi:"MI:0027"(cosedimentation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900347|imex:IM-24454-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	ensemblfungi:YOR310C(gene)|ensemblfungi:YOR310C_mRNA(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0017069"(snRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-4570464|reactome:R-SCE-6791226|rcsb pdb:6ZQC|refseq:NP_014955.1|sgd:S000005837|dip:DIP-5843N|mint:Q12499	-	-	crc64:8A2889448B2A19E2	figure legend:Fig 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/03/31	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	rogid:Dtk1A6GOVO3KgTak8cTHjO+eDQ4559292	-	false	green fluorescent protein tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06106	intact:EBI-10821792	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	rnacentral:URS0000444F9B_559292	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:snru3a yeast(display_short)|psi-mi:EBI-10821792(display_long)	psi-mi:"MI:0027"(cosedimentation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900347|imex:IM-24454-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	-	-	-	figure legend:Fig 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/03/31	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	-	-	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q06106	intact:EBI-10889363	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	-	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:rrna 20s(display_short)|psi-mi:EBI-10889363(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900267|imex:IM-24454-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0608"(ribosomal rna)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	-	-	-	figure legend:Fig6B|comment:22.5S also coprecipitate with the complex, but it is probably an unnatural isoform|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/03/31	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	-	-	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q06106	intact:EBI-10896468	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	-	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:rrna 23s(display_short)|psi-mi:EBI-10896468(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900267|imex:IM-24454-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0608"(ribosomal rna)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	-	-	-	figure legend:Fig6B|comment:22.5S also coprecipitate with the complex, but it is probably an unnatural isoform|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/03/31	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	-	-	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q06106	intact:EBI-10821792	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	rnacentral:URS0000444F9B_559292	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:snru3a yeast(display_short)|psi-mi:EBI-10821792(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900267|imex:IM-24454-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	-	-	-	figure legend:Fig6B|comment:22.5S also coprecipitate with the complex, but it is probably an unnatural isoform|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/03/31	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	-	-	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q06106	intact:EBI-10821555	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	rnacentral:URS00004BEF81_559292	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:rrna 35s yeast(display_short)|psi-mi:EBI-10821555(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900267|imex:IM-24454-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0608"(ribosomal rna)	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	sgd:S000006486(see-also)	-	-	-	figure legend:Fig6B|comment:22.5S also coprecipitate with the complex, but it is probably an unnatural isoform|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2016/03/31	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	-	-	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q06679	uniprotkb:Q06106	intact:EBI-35712|uniprotkb:D6VSV7|ensemblfungi:YDR324C	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	psi-mi:utp4_yeast(display_long)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:t-UTP4(gene name synonym)|uniprotkb:U three protein 4(gene name synonym)|uniprotkb:U3 protein 4 required for transcription(gene name synonym)|uniprotkb:YDR324C(locus name)	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:"MI:0027"(cosedimentation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10900379|imex:IM-24454-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010611.3|sgd:S000002732|mint:Q06679|dip:DIP-6436N|ensemblfungi:YDR324C(gene)|ensemblfungi:YDR324C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	crc64:5D1C77899CABB40B	-	figure legend:Fig7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2015/07/30	rogid:kAD4RO628jpcbjUoQXQbjcGVY88559292	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	rigid:YiqxlzW+QgIr+vjG/SR+vzhvkls	false	ha tag:n-n	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P25635	uniprotkb:Q06106	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	intact:EBI-34383|uniprotkb:D6W4B1|ensemblfungi:YPR112C	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:mrd1_yeast(display_long)|uniprotkb:MRD1(gene name)|psi-mi:MRD1(display_short)|uniprotkb:YPR112C(locus name)	psi-mi:"MI:0027"(cosedimentation)	Segerstolpe et al. (2008)	imex:IM-24454|pubmed:18586827	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10902987|imex:IM-24454-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N	refseq:NP_015437.1|sgd:S000006316|mint:Q06106|dip:DIP-6281N|ensemblfungi:YPR112C(gene)|ensemblfungi:YPR112C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0030686"(90S preribosome)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034482|interpro:IPR035979	-	crc64:CBEE4720F81378B6	-	figure legend:Fig7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/10	2015/07/30	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	rogid:lxiLbphBLtIbn1mguvZN+kFF570559292	rigid:UL8PXECXfTpyKs8RclmMQZNevOU	false	ha tag:n-n	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)