#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BZS1 uniprotkb:P51449 intact:EBI-983719|uniprotkb:O60827|uniprotkb:Q14DD8|intact:EBI-28970697|ensembl:ENSP00000365380|uniprotkb:Q4ZH51|uniprotkb:A5HJT1|uniprotkb:B7ZLG0|uniprotkb:B9UN80 intact:EBI-3908771|uniprotkb:Q8NCY8|uniprotkb:Q5SZR9|uniprotkb:Q8N5V7|ensembl:ENSP00000327025 psi-mi:foxp3_human(display_long)|uniprotkb:Scurfin(gene name synonym)|uniprotkb:FOXP3(gene name)|psi-mi:FOXP3(display_short)|uniprotkb:IPEX(gene name synonym)|uniprotkb:JM2(orf name) psi-mi:rorg_human(display_long)|uniprotkb:RORC(gene name)|psi-mi:RORC(display_short)|uniprotkb:NR1F3(gene name synonym)|uniprotkb:RORG(gene name synonym)|uniprotkb:RZRG(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2008) imex:IM-21986|pubmed:18368049 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-11179565|imex:IM-21986-2|dip:DIP-195713E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000376199|ensembl:ENSP00000365372|ensembl:ENSP00000365380|ensembl:ENST00000518685|ensembl:ENSP00000428952|ensembl:ENST00000557224|ensembl:ENSP00000451208|ensembl:ENSG00000049768(gene)|ensembl:ENST00000376207(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QRF|rcsb pdb:4WK8|reactome:R-HSA-8877330|reactome:R-HSA-8939256|dip:DIP-36584N|refseq:NP_001107849.1|refseq:NP_054728.2 refseq:NP_001001523.1|refseq:NP_005051.2|dip:DIP-60622N|ensembl:ENST00000318247(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048535"(lymph node development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|rcsb pdb:3B0W|rcsb pdb:3KYT|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:4NB6|rcsb pdb:4NIE|rcsb pdb:4QM0|rcsb pdb:4S14|rcsb pdb:4WLB|rcsb pdb:4WPF|rcsb pdb:4WQP|rcsb pdb:4XT9|rcsb pdb:4YMQ|rcsb pdb:4YPQ|rcsb pdb:4ZJR|rcsb pdb:4ZJW|rcsb pdb:4ZOM|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5APK|rcsb pdb:5AYG|rcsb pdb:5C4O|rcsb pdb:5C4S|rcsb pdb:5C4T|rcsb pdb:5C4U|rcsb pdb:5EJV|rcsb pdb:5ETH|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5G45|rcsb pdb:5G46|rcsb pdb:5IXK|rcsb pdb:5IZ0|rcsb pdb:5K38|rcsb pdb:5K3L|ensembl:ENSG00000143365(gene)|rcsb pdb:5K3M|rcsb pdb:5K3N|rcsb pdb:5K6E|rcsb pdb:5K74|rcsb pdb:5LWP|rcsb pdb:5M96|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5NTI|rcsb pdb:5NTK|rcsb pdb:5NTN|rcsb pdb:5NTP|rcsb pdb:5NTQ|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:5UFO|rcsb pdb:5UFR|rcsb pdb:5UHI|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5VQK|rcsb pdb:5VQL|rcsb pdb:5W4R|rcsb pdb:5W4V|rcsb pdb:5X8Q|rcsb pdb:5YP5|rcsb pdb:5YP6|rcsb pdb:5ZA1|rcsb pdb:6A22|rcsb pdb:6B30|rcsb pdb:6B31|rcsb pdb:6B33|rcsb pdb:6BN6|rcsb pdb:6BR2|rcsb pdb:6BR3|rcsb pdb:6CN5|rcsb pdb:6CN6|rcsb pdb:6CVH|rcsb pdb:6E3E|rcsb pdb:6E3G|rcsb pdb:6ESN|rcsb pdb:6FGQ|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|rcsb pdb:6IVX|rcsb pdb:6J1L|rcsb pdb:6J3N|rcsb pdb:6LO9|rcsb pdb:6LOA|rcsb pdb:6LOB|rcsb pdb:6LOC|rcsb pdb:6NAD|rcsb pdb:6NWS|rcsb pdb:6NWT|rcsb pdb:6NWU|rcsb pdb:6O3Z|rcsb pdb:6O98|rcsb pdb:6P9F|rcsb pdb:6Q2W|rcsb pdb:6Q6M|rcsb pdb:6Q6O|rcsb pdb:6Q7A|rcsb pdb:6Q7H|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SAL|rcsb pdb:6SLZ|rcsb pdb:6T4G|rcsb pdb:6T4I|rcsb pdb:6T4J|rcsb pdb:6T4K|rcsb pdb:6T4T|rcsb pdb:6T4U|rcsb pdb:6T4W|rcsb pdb:6T4X|rcsb pdb:6T4Y|rcsb pdb:6T50|rcsb pdb:6TLM|rcsb pdb:6TLQ|rcsb pdb:6TLT|rcsb pdb:6U25|rcsb pdb:6UCG|rcsb pdb:6VQF|rcsb pdb:6VSW|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XAE|rcsb pdb:6XFV|rcsb pdb:7JH2|rcsb pdb:7JTM|rcsb pdb:7JYM|rcsb pdb:7KCO|rcsb pdb:7KQJ|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|rcsb pdb:7LUK|rcsb pdb:7NEC|rcsb pdb:7NP5|rcsb pdb:7NP6|rcsb pdb:7NPC|reactome:R-HSA-383280|reactome:R-HSA-6785807|reactome:R-HSA-8949275 psi-mi:"MI:0465"(dip) - - figure legend:Fig. 3B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/09/08 2017/06/30 rogid:ZDAplrVbraZ3/8zn8GPK/CPkGnA9606 rogid:qkQ5csU6qSSESXrjWjdZ4zthECU9606 intact-crc:30AFC80B34C438DD|rigid:mLP4L4kpQGSVq3vW9V9pTNzh+Ho false necessary binding region:71..71-105..105 flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51450-2 uniprotkb:Q99JB6 intact:EBI-4422078 intact:EBI-10956246|ensembl:ENSMUSP00000041953|ensembl:ENSMUSP00000111403|ensembl:ENSMUSP00000111404|ensembl:ENSMUSP00000111405|ensembl:ENSMUSP00000157059|ensembl:ENSMUSP00000157093 psi-mi:p51450-2(display_long)|uniprotkb:RORgT(isoform synonym)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:foxp3_mouse(display_long)|uniprotkb:Foxp3(gene name)|psi-mi:Foxp3(display_short)|uniprotkb:Scurfin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2008) imex:IM-21986|pubmed:18368049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-11292913|imex:IM-21986-1|dip:DIP-195712E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4422044(isoform-parent) refseq:NP_001186276.1|refseq:NP_001186277.1|refseq:NP_473380.1|ensembl:ENSMUSG00000039521(gene)|ensembl:ENSMUST00000045566(transcript)|ensembl:ENSMUST00000115738(transcript)|ensembl:ENSMUST00000115739(transcript)|ensembl:ENSMUST00000115740(transcript)|ensembl:ENSMUST00000234363(transcript)|ensembl:ENSMUST00000235116(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002507"(tolerance induction)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050672"(negative regulation of lymphocyte proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4I1L|reactome:R-MMU-8877330|dip:DIP-59739N psi-mi:"MI:0465"(dip) isoform-comment:Produced by alternative promoter usage. - figure legend:Fig. 3A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/09/08 2017/06/30 rogid:Thnut5zIaRvLYyaPWY0tGVNC87k10090 rogid:KLiC5dIVXIMGQNgXoh6xzv2ozqE10090 intact-crc:389BA6FAB5D41249|rigid:zOARzfYk3BDxCUSN7zrOUxjUFXw false - flag tag:n-n|necessary binding region:70..70-104..104 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99JB6 uniprotkb:P51450-2 intact:EBI-10956246|ensembl:ENSMUSP00000041953|ensembl:ENSMUSP00000111403|ensembl:ENSMUSP00000111404|ensembl:ENSMUSP00000111405|ensembl:ENSMUSP00000157059|ensembl:ENSMUSP00000157093 intact:EBI-4422078 psi-mi:foxp3_mouse(display_long)|uniprotkb:Foxp3(gene name)|psi-mi:Foxp3(display_short)|uniprotkb:Scurfin(gene name synonym) psi-mi:p51450-2(display_long)|uniprotkb:RORgT(isoform synonym)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Zhou et al. (2008) imex:IM-21986|pubmed:18368049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0465"(DIP) intact:EBI-11291379|imex:IM-21986-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186276.1|refseq:NP_001186277.1|refseq:NP_473380.1|ensembl:ENSMUSG00000039521(gene)|ensembl:ENSMUST00000045566(transcript)|ensembl:ENSMUST00000115738(transcript)|ensembl:ENSMUST00000115739(transcript)|ensembl:ENSMUST00000115740(transcript)|ensembl:ENSMUST00000234363(transcript)|ensembl:ENSMUST00000235116(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002507"(tolerance induction)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050672"(negative regulation of lymphocyte proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4I1L|reactome:R-MMU-8877330|dip:DIP-59739N intact:EBI-4422044(isoform-parent) - - isoform-comment:Produced by alternative promoter usage. figure legend:Supplementary Fig. 4.|comment:FKH mutant remained in the cytoplasm even when it was co-expressed with ROR-gamma-t|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/09/08 2017/06/30 rogid:KLiC5dIVXIMGQNgXoh6xzv2ozqE10090 rogid:Thnut5zIaRvLYyaPWY0tGVNC87k10090 intact-crc:3F4C74684156CDF7|rigid:zOARzfYk3BDxCUSN7zrOUxjUFXw false flag tag:n-n - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P51450-2 uniprotkb:Q99JB6 intact:EBI-4422078 intact:EBI-10956246|ensembl:ENSMUSP00000041953|ensembl:ENSMUSP00000111403|ensembl:ENSMUSP00000111404|ensembl:ENSMUSP00000111405|ensembl:ENSMUSP00000157059|ensembl:ENSMUSP00000157093 psi-mi:p51450-2(display_long)|uniprotkb:RORgT(isoform synonym)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:foxp3_mouse(display_long)|uniprotkb:Foxp3(gene name)|psi-mi:Foxp3(display_short)|uniprotkb:Scurfin(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhou et al. (2008) imex:IM-21986|pubmed:18368049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0465"(DIP) intact:EBI-11293237|imex:IM-21986-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4422044(isoform-parent) refseq:NP_001186276.1|refseq:NP_001186277.1|refseq:NP_473380.1|ensembl:ENSMUSG00000039521(gene)|ensembl:ENSMUST00000045566(transcript)|ensembl:ENSMUST00000115738(transcript)|ensembl:ENSMUST00000115739(transcript)|ensembl:ENSMUST00000115740(transcript)|ensembl:ENSMUST00000234363(transcript)|ensembl:ENSMUST00000235116(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002507"(tolerance induction)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050672"(negative regulation of lymphocyte proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4I1L|reactome:R-MMU-8877330|dip:DIP-59739N - isoform-comment:Produced by alternative promoter usage. - figure legend:Fig. 1A, Suppementary Fig. 1A|comment:TGF-beta causes expression of the gamma-t isoform of ROR-gamma-t|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_cd4+)|taxid:10090(Mouse CD4 positive T-cell) - 2015/09/08 2017/06/30 rogid:Thnut5zIaRvLYyaPWY0tGVNC87k10090 rogid:KLiC5dIVXIMGQNgXoh6xzv2ozqE10090 intact-crc:0A864037BDA686B2|rigid:zOARzfYk3BDxCUSN7zrOUxjUFXw false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q99JB6 uniprotkb:P51450 intact:EBI-10956246|ensembl:ENSMUSP00000041953|ensembl:ENSMUSP00000111403|ensembl:ENSMUSP00000111404|ensembl:ENSMUSP00000111405|ensembl:ENSMUSP00000157059|ensembl:ENSMUSP00000157093 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 psi-mi:foxp3_mouse(display_long)|uniprotkb:Foxp3(gene name)|psi-mi:Foxp3(display_short)|uniprotkb:Scurfin(gene name synonym) psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhou et al. (2008) imex:IM-21986|pubmed:18368049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0465"(DIP) intact:EBI-11304313|imex:IM-21986-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186276.1|refseq:NP_001186277.1|refseq:NP_473380.1|ensembl:ENSMUSG00000039521(gene)|ensembl:ENSMUST00000045566(transcript)|ensembl:ENSMUST00000115738(transcript)|ensembl:ENSMUST00000115739(transcript)|ensembl:ENSMUST00000115740(transcript)|ensembl:ENSMUST00000234363(transcript)|ensembl:ENSMUST00000235116(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002362"(CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0002507"(tolerance induction)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002851"(positive regulation of peripheral T cell tolerance induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009615"(response to virus)|go:"GO:0010467"(gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048294"(negative regulation of isotype switching to IgE isotypes)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0050672"(negative regulation of lymphocyte proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051525"(NFAT protein binding)|go:"GO:1901355"(response to rapamycin)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4I1L|reactome:R-MMU-8877330|dip:DIP-59739N refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 - - - figure legend:Supplementary Fig. 1B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_cd4+)|taxid:10090(Mouse CD4 positive T-cell) - 2015/09/08 2017/06/30 rogid:KLiC5dIVXIMGQNgXoh6xzv2ozqE10090 rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 intact-crc:03C85028CD04E723|rigid:AkuBtTGnkWcDU0/ynERf+iTRyl4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)