#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06746	uniprotkb:P28352	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	intact:EBI-8418506|intact:MINT-4088018|ensembl:ENSMUSP00000042602	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:apex1_mouse(display_long)|uniprotkb:Apex1(gene name)|psi-mi:Apex1(display_short)|uniprotkb:Ape(gene name synonym)|uniprotkb:Apex(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)|uniprotkb:Ref1(gene name synonym)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951108|imex:IM-24999-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	refseq:NP_033817.1|ensembl:ENSMUSG00000035960(gene)|ensembl:ENSMUST00000049411(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P28352|rcsb pdb:7CD5|rcsb pdb:7CD6|reactome:R-MMU-110357|reactome:R-MMU-110362|reactome:R-MMU-110373|reactome:R-MMU-5651801|reactome:R-MMU-73930|reactome:R-MMU-73933	-	-	comment:mint|function:Repairs oxidative DNA damages in vitro. May have a role in protection against cell lethality and suppression of mutations. Removes the blocking groups from the 3'-termini of the DNA strand breaks generated by ionizing radiations and bleomycin	figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2015/07/30	2015/07/30	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rogid:fMTsVKLA4YjVrgOK0FCa3jpenbU10090	rigid:SXLxQjB6SI0XU7MTaalccW5pRto	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06746	uniprotkb:P39749	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	intact:EBI-10951074	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:fen1_mouse(display_long)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:Fen1(gene name)|psi-mi:Fen1(display_short)|uniprotkb:Fen-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951108|imex:IM-24999-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	reactome:R-MMU-110362|reactome:R-MMU-5651801|reactome:R-MMU-5685939|reactome:R-MMU-69166|interpro:IPR029060|interpro:IPR006086(XPG I)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR006085(XPG N-terminal)|interpro:IPR019974|interpro:IPR023426|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0007613"(memory)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR036279|reactome:R-MMU-174437	-	-	-	figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2015/07/30	2015/07/30	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rogid:0VAFBmO2Zkff+WKLwmYtlV34GyI10090	rigid:SXLxQjB6SI0XU7MTaalccW5pRto	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06746	uniprotkb:P63158	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	intact:EBI-6665811|ensembl:ENSMUSP00000082682|ensembl:ENSMUSP00000106131|ensembl:ENSMUSP00000106132|uniprotkb:P07155|uniprotkb:P27109|uniprotkb:P27428	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:hmgb1_mouse(display_long)|uniprotkb:Hmgb1(gene name)|psi-mi:Hmgb1(display_short)|uniprotkb:Hmg-1(gene name synonym)|uniprotkb:Hmg1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951108|imex:IM-24999-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	refseq:NP_001300823.1|ensembl:ENSMUSG00000066551(gene)|ensembl:ENSMUST00000085546(transcript)|ensembl:ENSMUST00000093196(transcript)|ensembl:ENSMUST00000110505(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000401"(open form four-way junction DNA binding)|go:"GO:0000402"(crossed form four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003681"(bent DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006284"(base-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008201"(heparin binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0005576"(extracellular region)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR036910|mint:P63158|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|reactome:R-MMU-140342|reactome:R-MMU-445989|reactome:R-MMU-5620971|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-933542|reactome:R-MMU-879415|refseq:NP_034569.1|refseq:XP_003945388.1	-	-	-	figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2015/07/30	2015/07/30	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rogid:Ujrs2BBefbmNxZj+S9H8lhWjnNc10090	rigid:SXLxQjB6SI0XU7MTaalccW5pRto	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63158	uniprotkb:P28352	intact:EBI-6665811|ensembl:ENSMUSP00000082682|ensembl:ENSMUSP00000106131|ensembl:ENSMUSP00000106132|uniprotkb:P07155|uniprotkb:P27109|uniprotkb:P27428	intact:EBI-8418506|intact:MINT-4088018|ensembl:ENSMUSP00000042602	psi-mi:hmgb1_mouse(display_long)|uniprotkb:Hmgb1(gene name)|psi-mi:Hmgb1(display_short)|uniprotkb:Hmg-1(gene name synonym)|uniprotkb:Hmg1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:apex1_mouse(display_long)|uniprotkb:Apex1(gene name)|psi-mi:Apex1(display_short)|uniprotkb:Ape(gene name synonym)|uniprotkb:Apex(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)|uniprotkb:Ref1(gene name synonym)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951153|imex:IM-24999-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300823.1|ensembl:ENSMUSG00000066551(gene)|ensembl:ENSMUST00000085546(transcript)|ensembl:ENSMUST00000093196(transcript)|ensembl:ENSMUST00000110505(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000401"(open form four-way junction DNA binding)|go:"GO:0000402"(crossed form four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003681"(bent DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006284"(base-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008201"(heparin binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0005576"(extracellular region)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR036910|mint:P63158|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|reactome:R-MMU-140342|reactome:R-MMU-445989|reactome:R-MMU-5620971|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-933542|reactome:R-MMU-879415|refseq:NP_034569.1|refseq:XP_003945388.1	refseq:NP_033817.1|ensembl:ENSMUSG00000035960(gene)|ensembl:ENSMUST00000049411(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P28352|rcsb pdb:7CD5|rcsb pdb:7CD6|reactome:R-MMU-110357|reactome:R-MMU-110362|reactome:R-MMU-110373|reactome:R-MMU-5651801|reactome:R-MMU-73930|reactome:R-MMU-73933	-	-	comment:mint|function:Repairs oxidative DNA damages in vitro. May have a role in protection against cell lethality and suppression of mutations. Removes the blocking groups from the 3'-termini of the DNA strand breaks generated by ionizing radiations and bleomycin	figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:Ujrs2BBefbmNxZj+S9H8lhWjnNc10090	rogid:fMTsVKLA4YjVrgOK0FCa3jpenbU10090	rigid:SXLxQjB6SI0XU7MTaalccW5pRto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63158	uniprotkb:P39749	intact:EBI-6665811|ensembl:ENSMUSP00000082682|ensembl:ENSMUSP00000106131|ensembl:ENSMUSP00000106132|uniprotkb:P07155|uniprotkb:P27109|uniprotkb:P27428	intact:EBI-10951074	psi-mi:hmgb1_mouse(display_long)|uniprotkb:Hmgb1(gene name)|psi-mi:Hmgb1(display_short)|uniprotkb:Hmg-1(gene name synonym)|uniprotkb:Hmg1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:fen1_mouse(display_long)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:Fen1(gene name)|psi-mi:Fen1(display_short)|uniprotkb:Fen-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951153|imex:IM-24999-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300823.1|ensembl:ENSMUSG00000066551(gene)|ensembl:ENSMUST00000085546(transcript)|ensembl:ENSMUST00000093196(transcript)|ensembl:ENSMUST00000110505(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000401"(open form four-way junction DNA binding)|go:"GO:0000402"(crossed form four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003681"(bent DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006284"(base-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008201"(heparin binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0005576"(extracellular region)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR036910|mint:P63158|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|reactome:R-MMU-140342|reactome:R-MMU-445989|reactome:R-MMU-5620971|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-933542|reactome:R-MMU-879415|refseq:NP_034569.1|refseq:XP_003945388.1	reactome:R-MMU-110362|reactome:R-MMU-5651801|reactome:R-MMU-5685939|reactome:R-MMU-69166|interpro:IPR029060|interpro:IPR006086(XPG I)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR006085(XPG N-terminal)|interpro:IPR019974|interpro:IPR023426|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0007613"(memory)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR036279|reactome:R-MMU-174437	-	-	-	figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:Ujrs2BBefbmNxZj+S9H8lhWjnNc10090	rogid:0VAFBmO2Zkff+WKLwmYtlV34GyI10090	rigid:SXLxQjB6SI0XU7MTaalccW5pRto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63158	uniprotkb:P06746	intact:EBI-6665811|ensembl:ENSMUSP00000082682|ensembl:ENSMUSP00000106131|ensembl:ENSMUSP00000106132|uniprotkb:P07155|uniprotkb:P27109|uniprotkb:P27428	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	psi-mi:hmgb1_mouse(display_long)|uniprotkb:Hmgb1(gene name)|psi-mi:Hmgb1(display_short)|uniprotkb:Hmg-1(gene name synonym)|uniprotkb:Hmg1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951153|imex:IM-24999-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300823.1|ensembl:ENSMUSG00000066551(gene)|ensembl:ENSMUST00000085546(transcript)|ensembl:ENSMUST00000093196(transcript)|ensembl:ENSMUST00000110505(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000401"(open form four-way junction DNA binding)|go:"GO:0000402"(crossed form four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003681"(bent DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006284"(base-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008201"(heparin binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0005576"(extracellular region)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR036910|mint:P63158|rcsb pdb:5ZDZ|rcsb pdb:5ZE0|rcsb pdb:5ZE1|rcsb pdb:5ZE2|reactome:R-MMU-140342|reactome:R-MMU-445989|reactome:R-MMU-5620971|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-933542|reactome:R-MMU-879415|refseq:NP_034569.1|refseq:XP_003945388.1	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	-	-	-	figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:Ujrs2BBefbmNxZj+S9H8lhWjnNc10090	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rigid:SXLxQjB6SI0XU7MTaalccW5pRto	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06746	uniprotkb:P27695	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951214|imex:IM-24999-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N	-	-	-	figure legend:6C|comment:FEN1 is found associated but cannot be mapped to UniProt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606	rigid:vwpOQ0Nxv7+lRVFhrprsvbW5XkA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06746	uniprotkb:P09429	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951214|imex:IM-24999-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	-	-	-	figure legend:6C|comment:FEN1 is found associated but cannot be mapped to UniProt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rigid:vwpOQ0Nxv7+lRVFhrprsvbW5XkA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09429	uniprotkb:P27695	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951238|imex:IM-24999-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N	-	-	-	figure legend:6D|comment:FEN1 is found associated but cannot be mapped to UniProt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606	rigid:vwpOQ0Nxv7+lRVFhrprsvbW5XkA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09429	uniprotkb:P06746	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678	intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (2007)	imex:IM-24999|pubmed:17803946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10951238|imex:IM-24999-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N	ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381	-	-	-	figure legend:6D|comment:FEN1 is found associated but cannot be mapped to UniProt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/30	2015/07/30	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606	rigid:vwpOQ0Nxv7+lRVFhrprsvbW5XkA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)