#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P30626-1	uniprotkb:P30626-1	intact:EBI-10816740|ensembl:ENSP00000265729	intact:EBI-10816740|ensembl:ENSP00000265729	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816738|wwpdb:2jc2|imex:IM-24154-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	-	-	-	figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:R work  0.252   R free   0.289|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/27	2015/05/15	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rigid:cPN4iMltS3BqrQcDohWl4DP55oQ	false	mutation:112-112	mutation:112-112	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30626-1	uniprotkb:P30626-1	intact:EBI-10816740|ensembl:ENSP00000265729	intact:EBI-10816740|ensembl:ENSP00000265729	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816841|imex:IM-24154-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	-	-	-	figure legend:Figure 6|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/27	2015/05/08	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rigid:cPN4iMltS3BqrQcDohWl4DP55oQ	false	mutation:112-112	mutation:112-112	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30626-1	uniprotkb:P30626-1	intact:EBI-10816740|ensembl:ENSP00000265729	intact:EBI-10816740|ensembl:ENSP00000265729	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816851|imex:IM-24154-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	-	-	-	figure legend:Figure 6i|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/27	2015/05/08	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rigid:cPN4iMltS3BqrQcDohWl4DP55oQ	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:39124"	uniprotkb:P30626-1	intact:EBI-10816878	intact:EBI-10816740|ensembl:ENSP00000265729	psi-mi:calcium ion(display_short)|psi-mi:"CHEBI:39124"(display_long)|intact:calcium ion(synonym)|intact:calcium ions(synonym)	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816872|imex:IM-24154-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	-	-	-	figure legend:none- text between  figs 6 and 7|comment:The F112L mutation therefore results in a 5- to 6-fold decrease in the affinity for Ca2+.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.7x10^-6(molar)	2015/04/27	2015/05/08	-	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:39124"	uniprotkb:P30626-1	intact:EBI-10816878	intact:EBI-10816740|ensembl:ENSP00000265729	psi-mi:calcium ion(display_short)|psi-mi:"CHEBI:39124"(display_long)|intact:calcium ion(synonym)|intact:calcium ions(synonym)	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816865|imex:IM-24154-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	-	-	-	figure legend:none- text between  figs 6 and 7|comment:The F112L mutation therefore results in a 5- to 6-fold decrease in the affinity for Ca2+.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.0x10^-6(molar)	2015/04/27	2015/05/08	-	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	-	false	-	mutation:112-112	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30626-1	uniprotkb:P20073	intact:EBI-10816740|ensembl:ENSP00000265729	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|intact:EBI-28973842|ensembl:ENSP00000362010	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816899|imex:IM-24154-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	ensembl:ENSP00000362010|ensembl:ENST00000372921|ensembl:ENSP00000362012|refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279(gene)|ensembl:ENST00000372919(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061025"(membrane fusion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104	-	-	-	figure legend:Figure 7|comment:By assuming that the sorcin dimer contains a single effective annexin VII binding site, the analysis yields KD values of 1.25 μM for wt-sorcin and 13.5 μM for F112L-sorcin.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:27.0x10^-6(molar)	2015/04/27	2015/05/08	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	rigid:vZ0b8oavo2vZ2jmjN6YdQKJ6Hko	false	mutation:112-112	sufficient binding region:1-20	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20073	uniprotkb:P30626-1	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|intact:EBI-28973842|ensembl:ENSP00000362010	intact:EBI-10816740|ensembl:ENSP00000265729	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Franceschini et al. (2008)	pubmed:17699613|imex:IM-24154	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10816906|imex:IM-24154-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000362010|ensembl:ENST00000372921|ensembl:ENSP00000362012|refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279(gene)|ensembl:ENST00000372919(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061025"(membrane fusion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104	intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)	-	-	-	figure legend:Figure 7|comment:By assuming that the sorcin dimer contains a single effective annexin VII binding site, the analysis yields KD values of 1.25 μM for wt-sorcin and 13.5 μM for F112L-sorcin.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.5x10^-6(molar)	2015/04/27	2015/05/08	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	rogid:upE31IMimaotkgnYa7HYr7EYAxc9606	rigid:vZ0b8oavo2vZ2jmjN6YdQKJ6Hko	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)