#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P97767	uniprotkb:Q8N196	intact:EBI-1368503|uniprotkb:G5E864|uniprotkb:O08818|ensembl:ENSMUSP00000027066|ensembl:ENSMUSP00000141112	intact:EBI-946167|ensembl:ENSP00000316842	psi-mi:eya1_mouse(display_long)|uniprotkb:Eya1(gene name)|psi-mi:Eya1(display_short)	psi-mi:six5_human(display_long)|uniprotkb:SIX5(gene name)|psi-mi:SIX5(display_short)|uniprotkb:DMAHP(gene name synonym)|uniprotkb:DM locus-associated homeodomain protein(gene name synonym)|uniprotkb:Sine oculis homeobox homolog 5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hoskins et al. (2007)	pubmed:17357085|imex:IM-24862	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-11425443|imex:IM-24862-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001297388.1|refseq:XP_017170837.1|ensembl:ENSMUST00000190337(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007389"(pattern specification process)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|ensembl:ENSMUST00000027066(transcript)|ensembl:ENSMUSG00000025932(gene)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071600"(otic vesicle morphogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0045739"(positive regulation of DNA repair)|interpro:IPR028471|interpro:IPR028472|interpro:IPR038102|interpro:IPR042577|reactome:R-MMU-5693565|interpro:IPR006545(EYA)	refseq:NP_787071.2|ensembl:ENSP00000316842|ensembl:ENSG00000177045(gene)|ensembl:ENST00000317578(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR031701	omim:610896(see-also)	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/11/26	2015/12/08	rogid:uKPeKeQrf3qnLAV2fWPXVf9WVug10090	rogid:/6UktdCF3v6kReBhbokaJOJyKe49606	rigid:TaDYgMu7/R4J2glqn/t90pw5t+A	false	sufficient binding region:321-591(IPR006545)	mutation decreasing interaction:158-158|mutation decreasing interaction:552-552	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)