#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75475-1 uniprotkb:P12497-PRO_0000042402 intact:EBI-5279836|ensembl:ENSP00000370109|ensembl:ENSP00000370114 intact:EBI-10131955 psi-mi:o75475-1(display_long)|uniprotkb:p75(isoform synonym)|uniprotkb:PSIP1(isoform synonym)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym) psi-mi:p12497-pro_0000042402(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0096"(pull down) Busschots et al. (2007) pubmed:17137594|imex:IM-23833 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-10132219|imex:IM-23833-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1801773(isoform-parent)|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript) intact:EBI-1026248(chain-parent) - isoform-comment:Less active than isoform 2 as transcriptional coactivator, but more abundant in cells. chain-seq-start:1148|chain-seq-end:1435 figure legend:2b and Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/11 2015/02/13 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 rogid:BCopeG10uQbkzoPkz/AccRsNPSo11698 intact-crc:7B64ED9A68E26A10|rigid:QW0QjL90iKQpP5M+oh4EKUCTZPM false - mutation increasing interaction:64-64|mutation decreasing interaction:168-168|mutation disrupting interaction:166-166|mutation disrupting interaction:132-132|mutation disrupting interaction:131-131|his tag:n-n|mutation decreasing interaction:170-170|mutation disrupting interaction:165-165|mutation decreasing interaction:161-161 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O75475-1 uniprotkb:P12497-PRO_0000042402 intact:EBI-5279836|ensembl:ENSP00000370109|ensembl:ENSP00000370114 intact:EBI-10131955 psi-mi:o75475-1(display_long)|uniprotkb:p75(isoform synonym)|uniprotkb:PSIP1(isoform synonym)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym) psi-mi:p12497-pro_0000042402(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0096"(pull down) Busschots et al. (2007) pubmed:17137594|imex:IM-23833 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-10131963|imex:IM-23833-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1801773(isoform-parent)|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript) intact:EBI-1026248(chain-parent) - isoform-comment:Less active than isoform 2 as transcriptional coactivator, but more abundant in cells. chain-seq-start:1148|chain-seq-end:1435 figure legend:2a and Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/11 2015/02/13 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 rogid:BCopeG10uQbkzoPkz/AccRsNPSo11698 intact-crc:DAD359349CA4A880|rigid:QW0QjL90iKQpP5M+oh4EKUCTZPM false - mutation disrupting interaction:132-132|his tag:c-c|mutation decreasing interaction:161-161|mutation disrupting interaction:166-166|mutation decreasing interaction:167-167|mutation decreasing interaction:168-168|mutation decreasing interaction:170-170|mutation decreasing interaction:131-131|mutation decreasing interaction:164-164|mutation decreasing interaction:165-165 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O75475-1 uniprotkb:P12497-PRO_0000042402 intact:EBI-5279836|ensembl:ENSP00000370109|ensembl:ENSP00000370114 intact:EBI-10131955 psi-mi:o75475-1(display_long)|uniprotkb:p75(isoform synonym)|uniprotkb:PSIP1(isoform synonym)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym) psi-mi:p12497-pro_0000042402(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0096"(pull down) Busschots et al. (2007) pubmed:17137594|imex:IM-23833 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-10132371|imex:IM-23833-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1801773(isoform-parent)|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript) intact:EBI-1026248(chain-parent) - isoform-comment:Less active than isoform 2 as transcriptional coactivator, but more abundant in cells. chain-seq-start:1148|chain-seq-end:1435 figure legend:2b|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/02/11 2015/02/13 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 rogid:BCopeG10uQbkzoPkz/AccRsNPSo11698 intact-crc:6A3E47B793ABDB8C|rigid:QW0QjL90iKQpP5M+oh4EKUCTZPM false - his tag:n-n|mutation disrupting interaction:165-165|mutation decreasing interaction:168-168|mutation disrupting interaction:166-166|mutation disrupting interaction:131-131|mutation disrupting interaction:132-132 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)