#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04150	ensembl:ENSG00000117560	intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	intact:EBI-10056645	psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)	psi-mi:tnfl6_human_gene(display_short)|psi-mi:ENSG00000117560(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10057002|imex:IM-23684-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N	-	-	-	-	figure legend:Fig. 5c|agonist:"dexamethasone (Dex) (CHEBI:41879) (10E-7 M for 30 minutes)"|causality statement:P04150 decreases expression at RNA level of ENSG00000117560|causality statement:"CHEBI:41879 indirectly decreases expression at RNA level of ENSG00000117560"|causality statement:"CHEBI:41879 increases binding of P04150 to ENSG00000117560"|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2015/01/14	2015/01/14	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	-	intact-crc:FD622143F5FD5C16	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000117560	uniprotkb:P19838-PRO_0000030311	intact:EBI-10056645	intact:EBI-697771	psi-mi:tnfl6_human_gene(display_short)|psi-mi:ENSG00000117560(display_long)	psi-mi:p19838-pro_0000030311(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10057019|imex:IM-23684-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	intact:EBI-300010(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:433	figure legend:Fig. 5c|antagonist:"dexamethasone (Dex) (CHEBI:41879) (10E-7 M for 30 minutes)"|causality statement:P04150 decreases binding of P19838-PRO_0000030311 to ENSG00000117560|causality statement:"CHEBI:41879 decreases binding of P19838-PRO_0000030311 to ENSG00000117560"|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2015/01/14	2015/01/14	-	rogid:ZgJEP6sTCusv6e6HxIkMJ5Yuv1E9606	intact-crc:41C4D8378BEE4135	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P19838-PRO_0000030311	intact:EBI-10057191	intact:EBI-697771	-	psi-mi:p19838-pro_0000030311(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:2x-nfkb-re_dna-probe(display_short)|psi-mi:EBI-10057191(display_long)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059257|imex:IM-23684-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	intact:EBI-300010(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:433	-	figure legend:Fig. 5b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	rogid:ZgJEP6sTCusv6e6HxIkMJ5Yuv1E9606	-	intact-crc:BCE8E9AE964DF275	false	-	biotin tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P19838-PRO_0000030311	intact:EBI-10057141	intact:EBI-697771	-	psi-mi:p19838-pro_0000030311(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:tnfl6_human_ngre/-990_dna-probe(display_short)|psi-mi:EBI-10057141(display_long)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059283|imex:IM-23684-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	intact:EBI-300010(chain-parent)	ensembl:ENSG00000117560(see-also)	-	chain-seq-start:1|chain-seq-end:433	-	figure legend:Fig. 5b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	rogid:ZgJEP6sTCusv6e6HxIkMJ5Yuv1E9606	-	intact-crc:D9551A39090FEA10	false	-	biotin tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-10057141	uniprotkb:P04150	-	intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	psi-mi:tnfl6_human_ngre/-990_dna-probe(display_short)|psi-mi:EBI-10057141(display_long)	psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059299|imex:IM-23684-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117560(see-also)	refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N	-	-	-	figure legend:Fig. 5b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	-	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	intact-crc:34F12F360D90EAD0	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-10057141	uniprotkb:P19838-PRO_0000030311	-	intact:EBI-697771	psi-mi:tnfl6_human_ngre/-990_dna-probe(display_short)|psi-mi:EBI-10057141(display_long)	psi-mi:p19838-pro_0000030311(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059299|imex:IM-23684-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117560(see-also)	intact:EBI-300010(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:433	figure legend:Fig. 5b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	-	rogid:ZgJEP6sTCusv6e6HxIkMJ5Yuv1E9606	intact-crc:34F12F360D90EAD0	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04150	intact:EBI-10057141	intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	-	psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)	psi-mi:tnfl6_human_ngre/-990_dna-probe(display_short)|psi-mi:EBI-10057141(display_long)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059323|imex:IM-23684-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N	ensembl:ENSG00000117560(see-also)	-	-	-	figure legend:Fig. 5b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	-	intact-crc:C0BD0E72D5986085	false	-	biotin tag:?-?|mutation disrupting interaction:21-21,25-25	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04150	intact:EBI-10057141	intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	-	psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)	psi-mi:tnfl6_human_ngre/-990_dna-probe(display_short)|psi-mi:EBI-10057141(display_long)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059350|imex:IM-23684-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N	ensembl:ENSG00000117560(see-also)	-	-	-	figure legend:Fig. 4a, 4b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	-	intact-crc:E0DDE027A1B7F8E5	false	-	biotin tag:?-?|mutation disrupting interaction:21-21,25-25	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04150	intact:EBI-10057170	intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	-	psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)	psi-mi:atty_rat_gre_dna-probe(display_short)|psi-mi:EBI-10057170(display_long)	psi-mi:"MI:0096"(pull down)	Novac et al. (2006)	pubmed:16770006|imex:IM-23684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10059375|imex:IM-23684-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N	ensembl:ENSRNOG00000016348(see-also)	-	-	-	figure legend:Fig. 4b|dataset:Crohn's disease - Interactions of proteins identified as having a link to Crohn's disease|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/14	2015/01/14	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	-	intact-crc:F69A2DD3642AB3AC	false	-	biotin tag:?-?|mutation disrupting interaction:14-14,20-20	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)