#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8NC56	uniprotkb:P02545-2	intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539	intact:EBI-351953|ensembl:ENSP00000357284|ensembl:ENSP00000503633	psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short)	psi-mi:p02545-2(display_long)|uniprotkb:Lamin C(isoform synonym)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Brachner et al. (2005)	imex:IM-24368|pubmed:16339967	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10901761|imex:IM-24368-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328	intact:EBI-351935(lmna_human)|ensembl:ENSG00000160789(gene)|ensembl:ENST00000368301(transcript)|ensembl:ENST00000677389(transcript)|uniprotkb:P02545-2(isoform-parent)	-	-	-	figure legend:4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/14	2015/07/14	rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606	rogid:RtZwi4BrXwUeTfkySzlABqDw/nM9606	rigid:PkSkU72CkogyOLRRVcP0JtAZjzo	false	35s radiolabel:?-?|sufficient binding region:46-195	glutathione s tranferase tag:?-?|sufficient binding region:319-572	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P42166	uniprotkb:P02545-2	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	intact:EBI-351953|ensembl:ENSP00000357284|ensembl:ENSP00000503633	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:p02545-2(display_long)|uniprotkb:Lamin C(isoform synonym)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Brachner et al. (2005)	imex:IM-24368|pubmed:16339967	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10901864|imex:IM-24368-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	intact:EBI-351935(lmna_human)|ensembl:ENSG00000160789(gene)|ensembl:ENST00000368301(transcript)|ensembl:ENST00000677389(transcript)|uniprotkb:P02545-2(isoform-parent)	-	-	-	figure legend:4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/14	2015/07/14	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	rogid:RtZwi4BrXwUeTfkySzlABqDw/nM9606	rigid:BXvHPUMbhtyfD/x3Wg73lEuVQkE	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|sufficient binding region:319-572	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8NC56	uniprotkb:P02545	intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771	psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Brachner et al. (2005)	imex:IM-24368|pubmed:16339967	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10901984|imex:IM-24368-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328	refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N	-	-	-	figure legend:7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2015/07/14	2015/07/16	rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rigid:D3fMyr1ydM218BdXS3gosoC3m7c	false	v5 tag:?-?	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)