#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46098 uniprotkb:P46098 intact:EBI-9008743|uniprotkb:O60854|uniprotkb:Q7KZM7|uniprotkb:Q99918|uniprotkb:Q9BSZ9|uniprotkb:B4DSY6|uniprotkb:G5E986|ensembl:ENSP00000424189 intact:EBI-9008743|uniprotkb:O60854|uniprotkb:Q7KZM7|uniprotkb:Q99918|uniprotkb:Q9BSZ9|uniprotkb:B4DSY6|uniprotkb:G5E986|ensembl:ENSP00000424189 psi-mi:5ht3a_human(display_long)|uniprotkb:HTR3A(gene name)|psi-mi:HTR3A(display_short)|uniprotkb:5-hydroxytryptamine receptor 3(gene name synonym)|uniprotkb:5HT3R(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Serotonin receptor 3A(gene name synonym)|uniprotkb:Serotonin-gated ion channel receptor(gene name synonym) psi-mi:5ht3a_human(display_long)|uniprotkb:HTR3A(gene name)|psi-mi:HTR3A(display_short)|uniprotkb:5-hydroxytryptamine receptor 3(gene name synonym)|uniprotkb:5HT3R(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Serotonin receptor 3A(gene name synonym)|uniprotkb:Serotonin-gated ion channel receptor(gene name synonym) psi-mi:"MI:0872"(atomic force microscopy) Barrera et al. (2005) imex:IM-24465|pubmed:16116092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11163778|imex:IM-24465-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155244.1|refseq:NP_998786.2|refseq:NP_000860.2|ensembl:ENSG00000166736(gene)|ensembl:ENST00000504030(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022850"(serotonin-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0050877"(nervous system process)|go:"GO:0051378"(serotonin binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904602"(serotonin-activated cation-selective channel complex)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR008132(5-hydroxytryptamine 3 receptor)|interpro:IPR008133(5-hydroxytryptamine 3 receptor, A subunit)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-HSA-112314 refseq:NP_001155244.1|refseq:NP_998786.2|refseq:NP_000860.2|ensembl:ENSG00000166736(gene)|ensembl:ENST00000504030(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022850"(serotonin-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0050877"(nervous system process)|go:"GO:0051378"(serotonin binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904602"(serotonin-activated cation-selective channel complex)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR008132(5-hydroxytryptamine 3 receptor)|interpro:IPR008133(5-hydroxytryptamine 3 receptor, A subunit)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-HSA-112314 - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/08/13 2015/08/14 rogid:SqoCjKrZZe5otDgS5KIY1QjUoF89606 rogid:SqoCjKrZZe5otDgS5KIY1QjUoF89606 rigid:dJ7ffU2j9sKgRx97T5djWWIdXqo false myc tag:c-c|his tag:c-c myc tag:c-c|his tag:c-c 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95264 uniprotkb:P46098 intact:EBI-9008726|uniprotkb:B0YJ23|uniprotkb:Q0VJC3|ensembl:ENSP00000260191 intact:EBI-9008743|uniprotkb:O60854|uniprotkb:Q7KZM7|uniprotkb:Q99918|uniprotkb:Q9BSZ9|uniprotkb:B4DSY6|uniprotkb:G5E986|ensembl:ENSP00000424189 psi-mi:5ht3b_human(display_long)|uniprotkb:HTR3B(gene name)|psi-mi:HTR3B(display_short)|uniprotkb:Serotonin receptor 3B(gene name synonym) psi-mi:5ht3a_human(display_long)|uniprotkb:HTR3A(gene name)|psi-mi:HTR3A(display_short)|uniprotkb:5-hydroxytryptamine receptor 3(gene name synonym)|uniprotkb:5HT3R(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Serotonin receptor 3A(gene name synonym)|uniprotkb:Serotonin-gated ion channel receptor(gene name synonym) psi-mi:"MI:0872"(atomic force microscopy) Barrera et al. (2005) imex:IM-24465|pubmed:16116092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11163796|imex:IM-24465-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011541365.1|refseq:NP_006019.1|ensembl:ENSG00000149305(gene)|ensembl:ENST00000260191(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009986"(cell surface)|go:"GO:0022850"(serotonin-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:1904602"(serotonin-activated cation-selective channel complex)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR008132(5-hydroxytryptamine 3 receptor)|interpro:IPR008134(5-hydroxytryptamine 3 receptor, B subunit)|interpro:IPR036719|interpro:IPR036734|reactome:R-HSA-112314 refseq:NP_001155244.1|refseq:NP_998786.2|refseq:NP_000860.2|ensembl:ENSG00000166736(gene)|ensembl:ENST00000504030(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022850"(serotonin-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0050877"(nervous system process)|go:"GO:0051378"(serotonin binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904602"(serotonin-activated cation-selective channel complex)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR008132(5-hydroxytryptamine 3 receptor)|interpro:IPR008133(5-hydroxytryptamine 3 receptor, A subunit)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-HSA-112314 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/08/13 2015/08/14 rogid:jtLQsB+qo6/8wmr0udigU7iuIeM9606 rogid:SqoCjKrZZe5otDgS5KIY1QjUoF89606 rigid:7XqKcjoS4Xuwf/OrUeVR6xY/Yo0 false his tag:c-c|v5 tag:c-c myc tag:c-c|his tag:c-c 3 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)