#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G3H0F0 uniprotkb:O14901 intact:EBI-10056318|ensembl:ENSCGRP00001028229|ensembl:ENSCGRP00015033537 intact:EBI-948266|ensembl:ENSP00000307023|uniprotkb:Q9EPF4|uniprotkb:B4DZE7 psi-mi:g3h0f0_crigr(display_long)|uniprotkb:I79_003605(orf name) psi-mi:klf11_human(display_long)|uniprotkb:Transforming growth factor-beta-inducible early growth response protein 2(gene name synonym)|uniprotkb:KLF11(gene name)|psi-mi:KLF11(display_short)|uniprotkb:FKLF(gene name synonym)|uniprotkb:TIEG2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neve et al. (2005) pubmed:15774581 taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10056284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_003497969.1|refseq:XP_007613406.1|refseq:XP_007613407.1|refseq:XP_007613408.1|refseq:XP_007617867.1|refseq:XP_007617872.1|refseq:XP_007617884.1|refseq:XP_016821903.1|refseq:XP_016823776.1|ensembl:ENSCGRG00015025232(gene)|ensembl:ENSCGRT00001032477(transcript)|ensembl:ENSCGRT00015040920(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|ensembl:ENSCGRG00001025002(gene)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774 ensembl:ENSG00000172059(gene)|ensembl:ENST00000305883(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1PO4|refseq:NP_001171187.1|refseq:NP_001171189.1|refseq:NP_003588.1 - - comment:"KLF11 MODY7 [MIM:610508] variants thr200met and ala347ser also interact and do not show alteration in binding affinity" figure legend:3A|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|dataset:Diabetes - Interactions investigated in the context of Diabetes|curation depth:mimix curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2015/01/13 2015/01/13 rogid:QnKrUhRLTNjFhS5vJ3JylLMNIDU10029 rogid:C656ulgovyTl6k1M7CB1iXycek09606 intact-crc:A103F22A92BE312C|rigid:sOHf3guZ0VTBJjJJ2ZU9rQL4qD4 false - flag tag:?-?|mutation increasing interaction:62-62 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)