#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7YRX0	uniprotkb:Q9XSK0	intact:EBI-10900951|ensembl:ENSBTAP00000012858	intact:EBI-8843794	psi-mi:rax2_bovin(display_long)|uniprotkb:RAX2(gene name)|psi-mi:RAX2(display_short)|uniprotkb:QRX(gene name synonym)|uniprotkb:RAXL1(gene name synonym)|uniprotkb:Q50-type retinal homeobox protein(gene name synonym)|uniprotkb:Retina and anterior neural fold homeobox-like protein 1(gene name synonym)	psi-mi:crx_bovin(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2004)	pubmed:15028672|imex:IM-24362	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10900971|imex:IM-24362-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_872594.1|refseq:XP_010805266.1|ensembl:ENSBTAG00000009750(gene)|ensembl:ENSBTAT00000012858(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0050896"(response to stimulus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR036934|interpro:IPR043562	refseq:NP_776329.1|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)	-	comment:Mutation R87Q corresponding to human disease variant R87Q in ARMD6 is interacting	-	figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/13	2015/07/13	rogid:BvnzRQ3oZNaet3Ujkbr3n5BkNS49913	rogid:ZhZHkVbubAn5HmPw2r9JnYWC8y49913	rigid:2YwUNfJc395JEF3bSi4BXmVvEhk	false	35s radiolabel:?-?|sufficient binding region:20-91(IPR001356)|mutation decreasing interaction:137-137|mutation decreasing interaction:138-139	sufficient binding region:34-107(IPR001356)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q96IS3	uniprotkb:O43186	intact:EBI-10901086|ensembl:ENSP00000450456|ensembl:ENSP00000450687	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	psi-mi:rax2_human(display_long)|uniprotkb:RAX2(gene name)|psi-mi:RAX2(display_short)|uniprotkb:QRX(gene name synonym)|uniprotkb:RAXL1(gene name synonym)|uniprotkb:Q50-type retinal homeobox protein(gene name synonym)|uniprotkb:Retina and anterior neural fold homeobox-like protein 1(gene name synonym)	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2004)	pubmed:15028672|imex:IM-24362	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10901107|imex:IM-24362-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116142.1|refseq:NP_001306003.1|ensembl:ENSG00000173976(gene)|ensembl:ENST00000555633(transcript)|ensembl:ENST00000555978(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR036934|interpro:IPR043562	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970	-	-	-	figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/07/13	2015/07/13	rogid:gLgeaXCZG/olLs9kvfUYUeOoEmQ9606	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rigid:7DbtIaEMvV9uP97x9OvHMojp/F4	false	xpress tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9XSK0	uniprotkb:P54845	intact:EBI-8843794	intact:EBI-8843813|uniprotkb:Q53XD0|uniprotkb:A8MX14|ensembl:ENSP00000380193|ensembl:ENSP00000380197|ensembl:ENSP00000454062|ensembl:ENSP00000495627|ensembl:ENSP00000496275|ensembl:ENSP00000496316	psi-mi:crx_bovin(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)	psi-mi:nrl_human(display_long)|uniprotkb:NRL(gene name)|psi-mi:NRL(display_short)|uniprotkb:D14S46E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2004)	pubmed:15028672|imex:IM-24362	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10901130|imex:IM-24362-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776329.1|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)	refseq:XP_011535104.1|refseq:XP_011535106.1|refseq:XP_011535107.1|refseq:NP_006168.1|refseq:XP_005267765.1|refseq:XP_005267766.1|refseq:XP_005267767.1|ensembl:ENSG00000129535(gene)|ensembl:ENSG00000285493(gene)|ensembl:ENST00000396997(transcript)|ensembl:ENST00000397002(transcript)|ensembl:ENST00000561028(transcript)|ensembl:ENST00000643394(transcript)|ensembl:ENST00000646526(transcript)|ensembl:ENST00000647376(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0050896"(response to stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR028575|interpro:IPR013592(Maf transcription factor, N-terminal)	-	-	-	figure legend:6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/13	2015/07/13	rogid:ZhZHkVbubAn5HmPw2r9JnYWC8y49913	rogid:Sm8+aReotDTTX1BjzsCXd66ryn49606	rigid:efHsRX61wf/LSnyV9YrbIuqP8tE	false	35s radiolabel:?-?|sufficient binding region:34-107	glutathione s tranferase tag:?-?|sufficient binding region:110-237	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O35602	uniprotkb:P54845	intact:EBI-10901180|uniprotkb:O08748|uniprotkb:Q6GT92|ensembl:ENSMUSP00000025396	intact:EBI-8843813|uniprotkb:Q53XD0|uniprotkb:A8MX14|ensembl:ENSP00000380193|ensembl:ENSP00000380197|ensembl:ENSP00000454062|ensembl:ENSP00000495627|ensembl:ENSP00000496275|ensembl:ENSP00000496316	psi-mi:rx_mouse(display_long)|uniprotkb:Rax(gene name)|psi-mi:Rax(display_short)|uniprotkb:Rx(gene name synonym)|uniprotkb:Retina and anterior neural fold homeobox protein(gene name synonym)	psi-mi:nrl_human(display_long)|uniprotkb:NRL(gene name)|psi-mi:NRL(display_short)|uniprotkb:D14S46E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2004)	pubmed:15028672|imex:IM-24362	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-10901175|imex:IM-24362-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038861.2|ensembl:ENSMUSG00000024518(gene)|ensembl:ENSMUST00000025396(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007420"(brain development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060173"(limb development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR043562	refseq:XP_011535104.1|refseq:XP_011535106.1|refseq:XP_011535107.1|refseq:NP_006168.1|refseq:XP_005267765.1|refseq:XP_005267766.1|refseq:XP_005267767.1|ensembl:ENSG00000129535(gene)|ensembl:ENSG00000285493(gene)|ensembl:ENST00000396997(transcript)|ensembl:ENST00000397002(transcript)|ensembl:ENST00000561028(transcript)|ensembl:ENST00000643394(transcript)|ensembl:ENST00000646526(transcript)|ensembl:ENST00000647376(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0050896"(response to stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR028575|interpro:IPR013592(Maf transcription factor, N-terminal)	-	-	-	figure legend:6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/07/13	2015/07/13	rogid:UKnSz8fGREf1liDEwwWURfnRwfA10090	rogid:Sm8+aReotDTTX1BjzsCXd66ryn49606	rigid:+xfgNFcZPnHv61DxvP/L7UNUYlE	false	35s radiolabel:?-?|sufficient binding region:130-200(IPR001356)	glutathione s tranferase tag:?-?|sufficient binding region:110-237	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)