#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q60641-1 uniprotkb:O70343-1 intact:EBI-11659377|ensembl:ENSMUSP00000100933 intact:EBI-11359934|ensembl:ENSMUSP00000117040 psi-mi:q60641-1(display_long)|uniprotkb:Nr1h4(gene name)|psi-mi:Nr1h4(display_short)|uniprotkb:Bar(gene name synonym)|uniprotkb:Fxr(gene name synonym)|uniprotkb:Rip14(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)|uniprotkb:"FXRalpha2(+)"(isoform synonym)|uniprotkb:FXRalpha3(isoform synonym)|uniprotkb:FXRbeta1(isoform synonym) psi-mi:o70343-1(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym)|uniprotkb:PGC-1a1(isoform synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2004) imex:IM-25280|pubmed:14729567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11360042|imex:IM-25280-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11359946(isoform-parent)|ensembl:ENSMUSG00000047638(gene)|ensembl:ENSMUST00000105296(transcript) intact:EBI-1371053(isoform-parent)|ensembl:ENSMUSG00000029167(gene)|ensembl:ENSMUST00000132734(transcript) - isoform-comment:Produced by alternative promoter usage. - figure legend:4 B/C/F|comment:"This is the interaction with the \"alpha-3\" form of FXR which has 488 residues - See figure 4A."|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/08/28 2016/05/16 rogid:LynOv9in3vUOon7KHdYMNhd9zrc10090 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rigid:MKYLQLIH1/ygr2EVGiXDzvUN+gg false 35s radiolabel:?-?|necessary binding region:137-203(IPR013088) glutathione s tranferase tag:n-n|sufficient binding region:1-400 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q60641-1 uniprotkb:O70343-1 intact:EBI-11659377|ensembl:ENSMUSP00000100933 intact:EBI-11359934|ensembl:ENSMUSP00000117040 psi-mi:q60641-1(display_long)|uniprotkb:Nr1h4(gene name)|psi-mi:Nr1h4(display_short)|uniprotkb:Bar(gene name synonym)|uniprotkb:Fxr(gene name synonym)|uniprotkb:Rip14(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)|uniprotkb:"FXRalpha2(+)"(isoform synonym)|uniprotkb:FXRalpha3(isoform synonym)|uniprotkb:FXRbeta1(isoform synonym) psi-mi:o70343-1(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym)|uniprotkb:PGC-1a1(isoform synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2004) imex:IM-25280|pubmed:14729567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11360097|imex:IM-25280-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11359946(isoform-parent)|ensembl:ENSMUSG00000047638(gene)|ensembl:ENSMUST00000105296(transcript) intact:EBI-1371053(isoform-parent)|ensembl:ENSMUSG00000029167(gene)|ensembl:ENSMUST00000132734(transcript) - isoform-comment:Produced by alternative promoter usage. - figure legend:4 D/E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/08/28 2016/05/16 rogid:LynOv9in3vUOon7KHdYMNhd9zrc10090 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rigid:MKYLQLIH1/ygr2EVGiXDzvUN+gg false glutathione s tranferase tag:n-n|sufficient binding region:137-203(IPR013088) 35s radiolabel:?-?|necessary binding region:181-400 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q60641-2 uniprotkb:O70343-1 intact:EBI-11659386|ensembl:ENSMUSP00000053092 intact:EBI-11359934|ensembl:ENSMUSP00000117040 psi-mi:q60641-2(display_long)|uniprotkb:Nr1h4(gene name)|psi-mi:Nr1h4(display_short)|uniprotkb:Bar(gene name synonym)|uniprotkb:Fxr(gene name synonym)|uniprotkb:Rip14(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)|uniprotkb:FXFRalpha4(isoform synonym)|uniprotkb:"FXRalpha2(-)"(isoform synonym)|uniprotkb:FXRbeta2(isoform synonym) psi-mi:o70343-1(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym)|uniprotkb:PGC-1a1(isoform synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2004) imex:IM-25280|pubmed:14729567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11701654|imex:IM-25280-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11359946(isoform-parent)|ensembl:ENSMUSG00000047638(gene)|ensembl:ENSMUST00000058126(transcript) intact:EBI-1371053(isoform-parent)|ensembl:ENSMUSG00000029167(gene)|ensembl:ENSMUST00000132734(transcript) - isoform-comment:Produced by alternative splicing of isoform 1. - figure legend:4B/F|comment:"This is the interaction with the \"alpha-4\" form of FXR which has 484 residues."|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/08/28 2016/05/16 rogid:VTDbC+GvYk7Z2gqMTpknE/32xX010090 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rigid:lb6GWyOpVnpwply6W3FxNBa35vU false 35s radiolabel:?-?|sufficient binding region:137-484(IPR013088) glutathione s tranferase tag:n-n|sufficient binding region:1-400 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q60641-1 uniprotkb:O70343-1 intact:EBI-11659377|ensembl:ENSMUSP00000100933 intact:EBI-11359934|ensembl:ENSMUSP00000117040 psi-mi:q60641-1(display_long)|uniprotkb:Nr1h4(gene name)|psi-mi:Nr1h4(display_short)|uniprotkb:Bar(gene name synonym)|uniprotkb:Fxr(gene name synonym)|uniprotkb:Rip14(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)|uniprotkb:"FXRalpha2(+)"(isoform synonym)|uniprotkb:FXRalpha3(isoform synonym)|uniprotkb:FXRbeta1(isoform synonym) psi-mi:o70343-1(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym)|uniprotkb:PGC-1a1(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2004) imex:IM-25280|pubmed:14729567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11360131|imex:IM-25280-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11359946(isoform-parent)|ensembl:ENSMUSG00000047638(gene)|ensembl:ENSMUST00000105296(transcript) intact:EBI-1371053(isoform-parent)|ensembl:ENSMUSG00000029167(gene)|ensembl:ENSMUST00000132734(transcript) - isoform-comment:Produced by alternative promoter usage. - figure legend:4G|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast) - 2015/08/28 2016/03/18 rogid:LynOv9in3vUOon7KHdYMNhd9zrc10090 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rigid:MKYLQLIH1/ygr2EVGiXDzvUN+gg false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60641-2 uniprotkb:O70343-1 intact:EBI-11659386|ensembl:ENSMUSP00000053092 intact:EBI-11359934|ensembl:ENSMUSP00000117040 psi-mi:q60641-2(display_long)|uniprotkb:Nr1h4(gene name)|psi-mi:Nr1h4(display_short)|uniprotkb:Bar(gene name synonym)|uniprotkb:Fxr(gene name synonym)|uniprotkb:Rip14(gene name synonym)|uniprotkb:Farnesoid X-activated receptor(gene name synonym)|uniprotkb:Farnesol receptor HRR-1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 4(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 14(gene name synonym)|uniprotkb:FXFRalpha4(isoform synonym)|uniprotkb:"FXRalpha2(-)"(isoform synonym)|uniprotkb:FXRbeta2(isoform synonym) psi-mi:o70343-1(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym)|uniprotkb:PGC-1a1(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2004) imex:IM-25280|pubmed:14729567 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11659355|imex:IM-25280-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11359946(isoform-parent)|ensembl:ENSMUSG00000047638(gene)|ensembl:ENSMUST00000058126(transcript) intact:EBI-1371053(isoform-parent)|ensembl:ENSMUSG00000029167(gene)|ensembl:ENSMUST00000132734(transcript) - isoform-comment:Produced by alternative splicing of isoform 1. - figure legend:4G-2|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast) - 2015/08/28 2016/03/18 rogid:VTDbC+GvYk7Z2gqMTpknE/32xX010090 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rigid:lb6GWyOpVnpwply6W3FxNBa35vU false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)