#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38688 uniprotkb:P38985 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11297417|imex:IM-24781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 - - - figure legend:Fig1,Fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 uniprotkb:P32342 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-17984|uniprotkb:D6VXG8|ensemblfungi:YKL122C psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp21_yeast(display_long)|uniprotkb:SRP21(gene name)|psi-mi:SRP21(display_short)|uniprotkb:YKL122C(locus name)|uniprotkb:YKL527(orf name)|uniprotkb:Signal recognition particle 21 kDa protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11297417|imex:IM-24781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_012800.1|sgd:S000001605|ensemblfungi:YKL122C(gene)|ensemblfungi:YKL122C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|interpro:IPR039432|reactome:R-SCE-1799339|dip:DIP-4863N|mint:P32342 - - - figure legend:Fig1,Fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:UXyZkJvr4xO44RgYpDeA8lsND/k559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 uniprotkb:P29478 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-16641|ensemblfungi:YML105C|uniprotkb:D6W0H9 psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:sec65_yeast(display_long)|uniprotkb:YM8339.14C(orf name)|uniprotkb:YML105C(locus name)|uniprotkb:SEC65(gene name)|psi-mi:SEC65(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11297417|imex:IM-24781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 ensemblfungi:YML105C_mRNA(transcript)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR022938|interpro:IPR036521|reactome:R-SCE-1799339|ensemblfungi:YML105C(gene)|refseq:NP_013602.1|sgd:S000004573|dip:DIP-3850N|mint:P29478 - - - figure legend:Fig1,Fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:CiyG70uBb2zHzMoIGaV6TaNj9lU559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 uniprotkb:P20424 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-17997|uniprotkb:D6W489|ensemblfungi:YPR088C psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp54_yeast(display_long)|uniprotkb:SRH1(gene name synonym)|uniprotkb:P9513.14(orf name)|uniprotkb:YPR088C(locus name)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short)|uniprotkb:Signal recognition particle 54 kDa protein homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11297417|imex:IM-24781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_015413.1|sgd:S000006292|ensemblfungi:YPR088C(gene)|ensemblfungi:YPR088C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|reactome:R-SCE-1799339|dip:DIP-2943N|mint:P20424 - - crc64:05B1B2C262932F17 figure legend:Fig1,Fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:vdpwRcH6Lq+zH/uN4XPPS4KLMow559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 uniprotkb:P38687 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-18004|uniprotkb:D6W3C8|ensemblfungi:YPL243W psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp68_yeast(display_long)|uniprotkb:YPL243W(locus name)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11297417|imex:IM-24781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_015081.1|sgd:S000006164|ensemblfungi:YPL243W(gene)|ensemblfungi:YPL243W_mRNA(transcript)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0034399"(nuclear periphery)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|reactome:R-SCE-1799339|dip:DIP-6742N|mint:P38687 - - - figure legend:Fig1,Fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:4cVGRebXokCZUy7he9W9JVzJJME559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 intact:EBI-11175111 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C rnacentral:URS00001CAAE9_559292 psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11297417|imex:IM-24781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0611"(signal recognition particle rna) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 - - - - figure legend:Fig1,Fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 - - false protein a tag:c-c binding-associated region:223-394 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0929"(northern blot) uniprotkb:P38688 uniprotkb:P38985 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11301108|imex:IM-24781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 - - - figure legend:Fig1,Fig3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 uniprotkb:P32342 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-17984|uniprotkb:D6VXG8|ensemblfungi:YKL122C psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp21_yeast(display_long)|uniprotkb:SRP21(gene name)|psi-mi:SRP21(display_short)|uniprotkb:YKL122C(locus name)|uniprotkb:YKL527(orf name)|uniprotkb:Signal recognition particle 21 kDa protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11301108|imex:IM-24781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_012800.1|sgd:S000001605|ensemblfungi:YKL122C(gene)|ensemblfungi:YKL122C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|interpro:IPR039432|reactome:R-SCE-1799339|dip:DIP-4863N|mint:P32342 - - - figure legend:Fig1,Fig3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:UXyZkJvr4xO44RgYpDeA8lsND/k559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 uniprotkb:P38687 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C intact:EBI-18004|uniprotkb:D6W3C8|ensemblfungi:YPL243W psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:srp68_yeast(display_long)|uniprotkb:YPL243W(locus name)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11301108|imex:IM-24781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 refseq:NP_015081.1|sgd:S000006164|ensemblfungi:YPL243W(gene)|ensemblfungi:YPL243W_mRNA(transcript)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0034399"(nuclear periphery)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|reactome:R-SCE-1799339|dip:DIP-6742N|mint:P38687 - - - figure legend:Fig1,Fig3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 rogid:4cVGRebXokCZUy7he9W9JVzJJME559292 - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P38688 intact:EBI-11175111 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C rnacentral:URS00001CAAE9_559292 psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11301108|imex:IM-24781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0611"(signal recognition particle rna) refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 - - - comment:In the absence of Srp54 and 65, ScR1 co-purificate with the complex, but the nuclease cleavage profile of ScR1 is different from the wild type. figure legend:Fig1,Fig3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/08 rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 - - false protein a tag:c-c - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0929"(northern blot) intact:EBI-11175111 uniprotkb:P38688 rnacentral:URS00001CAAE9_559292 intact:EBI-18011|uniprotkb:D6W3G0|ensemblfungi:YPL210C psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:srp72_yeast(display_long)|uniprotkb:YPL210C(locus name)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11301122|imex:IM-24781-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0611"(signal recognition particle rna) psi-mi:"MI:0326"(protein) - refseq:NP_015114.2|sgd:S000006131|reactome:R-SCE-1799339|ensemblfungi:YPL210C(gene)|ensemblfungi:YPL210C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR026270|dip:DIP-6763N|mint:P38688 - - - figure legend:Fig4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/23 - rogid:yhhZC25wybDaN4LOKK6P4/TPnRE559292 - false binding-associated region:228-394 protein a tag:c-c - - psi-mi:"MI:2203"(primer extension assay) psi-mi:"MI:2203"(primer extension assay) intact:EBI-11175111 uniprotkb:P29478 rnacentral:URS00001CAAE9_559292 intact:EBI-16641|ensemblfungi:YML105C|uniprotkb:D6W0H9 psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:sec65_yeast(display_long)|uniprotkb:YM8339.14C(orf name)|uniprotkb:YML105C(locus name)|uniprotkb:SEC65(gene name)|psi-mi:SEC65(display_short) psi-mi:"MI:0027"(cosedimentation) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11301414|imex:IM-24781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0611"(signal recognition particle rna) psi-mi:"MI:0326"(protein) - ensemblfungi:YML105C_mRNA(transcript)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR022938|interpro:IPR036521|reactome:R-SCE-1799339|ensemblfungi:YML105C(gene)|refseq:NP_013602.1|sgd:S000004573|dip:DIP-3850N|mint:P29478 - - - figure legend:Fig6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/09 - rogid:CiyG70uBb2zHzMoIGaV6TaNj9lU559292 - false mutation decreasing interaction:357-357|mutation decreasing interaction:331-331 - - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0113"(western blot) intact:EBI-11175111 uniprotkb:P38985 rnacentral:URS00001CAAE9_559292 intact:EBI-17977|uniprotkb:D6VRQ6|ensemblfungi:YDL092W psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:srp14_yeast(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:YDL092W(locus name)|uniprotkb:D2404(orf name)|uniprotkb:Signal recognition particle 14 kDa protein homolog(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11301414|imex:IM-24781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0611"(signal recognition particle rna) psi-mi:"MI:0326"(protein) - refseq:NP_010191.1|sgd:S000002250|ensemblfungi:YDL092W(gene)|ensemblfungi:YDL092W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|reactome:R-SCE-1799339|reactome:R-SCE-6798695|dip:DIP-4864N|mint:P38985 - - - figure legend:Fig6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/09 - rogid:I9myDFdKPRnrKsHBhWBxI/Em7EQ559292 - false mutation decreasing interaction:357-357|mutation decreasing interaction:331-331 - - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0113"(western blot) intact:EBI-11175111 uniprotkb:P20424 rnacentral:URS00001CAAE9_559292 intact:EBI-17997|uniprotkb:D6W489|ensemblfungi:YPR088C psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:srp54_yeast(display_long)|uniprotkb:SRH1(gene name synonym)|uniprotkb:P9513.14(orf name)|uniprotkb:YPR088C(locus name)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short)|uniprotkb:Signal recognition particle 54 kDa protein homolog(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11301414|imex:IM-24781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0611"(signal recognition particle rna) psi-mi:"MI:0326"(protein) - refseq:NP_015413.1|sgd:S000006292|ensemblfungi:YPR088C(gene)|ensemblfungi:YPR088C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|reactome:R-SCE-1799339|dip:DIP-2943N|mint:P20424 - - crc64:05B1B2C262932F17 figure legend:Fig6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/09 - rogid:vdpwRcH6Lq+zH/uN4XPPS4KLMow559292 - false mutation decreasing interaction:357-357|mutation decreasing interaction:331-331 - - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0113"(western blot) intact:EBI-11175111 uniprotkb:P38687 rnacentral:URS00001CAAE9_559292 intact:EBI-18004|uniprotkb:D6W3C8|ensemblfungi:YPL243W psi-mi:scr1 yeast(display_short)|psi-mi:EBI-11175111(display_long) psi-mi:srp68_yeast(display_long)|uniprotkb:YPL243W(locus name)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein homolog(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Van et al. (2004) imex:IM-24781|pubmed:14681587 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-11301414|imex:IM-24781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0611"(signal recognition particle rna) psi-mi:"MI:0326"(protein) - refseq:NP_015081.1|sgd:S000006164|ensemblfungi:YPL243W(gene)|ensemblfungi:YPL243W_mRNA(transcript)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0034399"(nuclear periphery)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|reactome:R-SCE-1799339|dip:DIP-6742N|mint:P38687 - - - figure legend:Fig6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/24 2015/10/09 - rogid:4cVGRebXokCZUy7he9W9JVzJJME559292 - false mutation decreasing interaction:357-357|mutation decreasing interaction:331-331 - - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0113"(western blot)