#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q06287	uniprotkb:Q99207	intact:EBI-11979|ensemblfungi:YLR186W|uniprotkb:E9P8U2|uniprotkb:D6VYI9	intact:EBI-35157|uniprotkb:D6VRK0|ensemblfungi:YDL148C	psi-mi:nep1_yeast(display_long)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:NEP1(gene name synonym)|uniprotkb:YLR186W(locus name)|uniprotkb:L9470.5(orf name)|uniprotkb:Nucleolar essential protein 1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1189)-N1)-methyltransferase"(gene name synonym)|uniprotkb:Essential for mitotic growth protein 1(gene name synonym)	psi-mi:nop14_yeast(display_long)|uniprotkb:NOP14(gene name)|psi-mi:NOP14(display_short)|uniprotkb:UTP2(gene name synonym)|uniprotkb:YDL148C(locus name)|uniprotkb:D1566(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 2(gene name synonym)|uniprotkb:U three protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liu et al. (2001)	pubmed:11694595|imex:IM-24374	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10902061|imex:IM-24374-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|ensemblfungi:YLR186W(gene)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:2V3J|rcsb pdb:2V3K|ensemblfungi:YLR186W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|rcsb pdb:3OIJ|rcsb pdb:3OIN|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:3OII|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|sgd:S000004176|refseq:NP_013287.1|reactome:R-SCE-6791226|dip:DIP-6504N	refseq:NP_010133.1|sgd:S000002307|mint:Q99207|dip:DIP-4733N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007276(Nop14-like protein)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|ensemblfungi:YDL148C(gene)|ensemblfungi:YDL148C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")	-	crc64:4A8FCDA812051AD1	crc64:F7615D96B02E15DE	figure legend:Fig3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/14	2015/07/14	rogid:z62Fg9aJ4kKGgU5NIlAND2yHGrQ559292	rogid:gI9SxINx8uFUHP91VaGXVXzjspQ559292	rigid:0TIlGWx8SAzqy1fgBH/Ekl9kC6o	false	gal4 dna binding domain:n-n	gal4 activation domain:n-n|sufficient binding region:170-469	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06287	uniprotkb:Q99207	intact:EBI-11979|ensemblfungi:YLR186W|uniprotkb:E9P8U2|uniprotkb:D6VYI9	intact:EBI-35157|uniprotkb:D6VRK0|ensemblfungi:YDL148C	psi-mi:nep1_yeast(display_long)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:NEP1(gene name synonym)|uniprotkb:YLR186W(locus name)|uniprotkb:L9470.5(orf name)|uniprotkb:Nucleolar essential protein 1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1189)-N1)-methyltransferase"(gene name synonym)|uniprotkb:Essential for mitotic growth protein 1(gene name synonym)	psi-mi:nop14_yeast(display_long)|uniprotkb:NOP14(gene name)|psi-mi:NOP14(display_short)|uniprotkb:UTP2(gene name synonym)|uniprotkb:YDL148C(locus name)|uniprotkb:D1566(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 2(gene name synonym)|uniprotkb:U three protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2001)	pubmed:11694595|imex:IM-24374	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10902110|imex:IM-24374-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|ensemblfungi:YLR186W(gene)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:2V3J|rcsb pdb:2V3K|ensemblfungi:YLR186W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|rcsb pdb:3OIJ|rcsb pdb:3OIN|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:3OII|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|sgd:S000004176|refseq:NP_013287.1|reactome:R-SCE-6791226|dip:DIP-6504N	refseq:NP_010133.1|sgd:S000002307|mint:Q99207|dip:DIP-4733N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007276(Nop14-like protein)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|ensemblfungi:YDL148C(gene)|ensemblfungi:YDL148C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")	-	crc64:4A8FCDA812051AD1	crc64:F7615D96B02E15DE	figure legend:Fig3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/14	2015/07/14	rogid:z62Fg9aJ4kKGgU5NIlAND2yHGrQ559292	rogid:gI9SxINx8uFUHP91VaGXVXzjspQ559292	rigid:0TIlGWx8SAzqy1fgBH/Ekl9kC6o	false	ha tag:n-n	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06287	uniprotkb:Q99207	intact:EBI-11979|ensemblfungi:YLR186W|uniprotkb:E9P8U2|uniprotkb:D6VYI9	intact:EBI-35157|uniprotkb:D6VRK0|ensemblfungi:YDL148C	psi-mi:nep1_yeast(display_long)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:NEP1(gene name synonym)|uniprotkb:YLR186W(locus name)|uniprotkb:L9470.5(orf name)|uniprotkb:Nucleolar essential protein 1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1189)-N1)-methyltransferase"(gene name synonym)|uniprotkb:Essential for mitotic growth protein 1(gene name synonym)	psi-mi:nop14_yeast(display_long)|uniprotkb:NOP14(gene name)|psi-mi:NOP14(display_short)|uniprotkb:UTP2(gene name synonym)|uniprotkb:YDL148C(locus name)|uniprotkb:D1566(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 2(gene name synonym)|uniprotkb:U three protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2001)	pubmed:11694595|imex:IM-24374	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10902150|imex:IM-24374-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|ensemblfungi:YLR186W(gene)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:2V3J|rcsb pdb:2V3K|ensemblfungi:YLR186W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|rcsb pdb:3OIJ|rcsb pdb:3OIN|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:3OII|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|sgd:S000004176|refseq:NP_013287.1|reactome:R-SCE-6791226|dip:DIP-6504N	refseq:NP_010133.1|sgd:S000002307|mint:Q99207|dip:DIP-4733N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007276(Nop14-like protein)|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|ensemblfungi:YDL148C(gene)|ensemblfungi:YDL148C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")	-	crc64:4A8FCDA812051AD1	crc64:F7615D96B02E15DE	figure legend:Fig3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/07/14	2015/07/14	rogid:z62Fg9aJ4kKGgU5NIlAND2yHGrQ559292	rogid:gI9SxINx8uFUHP91VaGXVXzjspQ559292	rigid:0TIlGWx8SAzqy1fgBH/Ekl9kC6o	false	ha tag:n-n	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)