#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H270 uniprotkb:Q9P253 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817255|imex:IM-24171-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/05/08 2015/05/08 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rigid:DWH7h6/GsUIfpB+UT3lYx0pvES8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H270 uniprotkb:Q9H269 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 intact:EBI-2655929|uniprotkb:Q5JUB1|uniprotkb:Q8WU31|uniprotkb:Q96EE7|uniprotkb:Q96N92|uniprotkb:Q9H1Q4|uniprotkb:Q9H1Q5|ensembl:ENSP00000369810 psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:vps16_human(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817255|imex:IM-24171-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) refseq:NP_072097.2|refseq:NP_536338.1|ensembl:ENSG00000215305(gene)|ensembl:ENST00000380445(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051015"(actin filament binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|mint:Q9H269|rcsb pdb:4BX9 - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/05/08 2015/05/08 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rogid:bm088LmFRv3w0wfvlPMFeottZkw9606 rigid:DWH7h6/GsUIfpB+UT3lYx0pvES8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P253 uniprotkb:Q9H269 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 intact:EBI-2655929|uniprotkb:Q5JUB1|uniprotkb:Q8WU31|uniprotkb:Q96EE7|uniprotkb:Q96N92|uniprotkb:Q9H1Q4|uniprotkb:Q9H1Q5|ensembl:ENSP00000369810 psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:vps16_human(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817260|imex:IM-24171-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) refseq:NP_072097.2|refseq:NP_536338.1|ensembl:ENSG00000215305(gene)|ensembl:ENST00000380445(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051015"(actin filament binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|mint:Q9H269|rcsb pdb:4BX9 - - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/05/08 2015/05/08 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rogid:bm088LmFRv3w0wfvlPMFeottZkw9606 rigid:DWH7h6/GsUIfpB+UT3lYx0pvES8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P253 uniprotkb:Q9H270 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817260|imex:IM-24171-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/05/08 2015/05/08 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:DWH7h6/GsUIfpB+UT3lYx0pvES8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H269 uniprotkb:Q9P253 intact:EBI-2655929|uniprotkb:Q5JUB1|uniprotkb:Q8WU31|uniprotkb:Q96EE7|uniprotkb:Q96N92|uniprotkb:Q9H1Q4|uniprotkb:Q9H1Q5|ensembl:ENSP00000369810 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 psi-mi:vps16_human(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short) psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817265|imex:IM-24171-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_072097.2|refseq:NP_536338.1|ensembl:ENSG00000215305(gene)|ensembl:ENST00000380445(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051015"(actin filament binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|mint:Q9H269|rcsb pdb:4BX9 ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) - - - figure legend:6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/05/08 2015/05/08 rogid:bm088LmFRv3w0wfvlPMFeottZkw9606 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rigid:DWH7h6/GsUIfpB+UT3lYx0pvES8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H269 uniprotkb:Q9H270 intact:EBI-2655929|uniprotkb:Q5JUB1|uniprotkb:Q8WU31|uniprotkb:Q96EE7|uniprotkb:Q96N92|uniprotkb:Q9H1Q4|uniprotkb:Q9H1Q5|ensembl:ENSP00000369810 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:vps16_human(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817265|imex:IM-24171-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_072097.2|refseq:NP_536338.1|ensembl:ENSG00000215305(gene)|ensembl:ENST00000380445(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051015"(actin filament binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|mint:Q9H269|rcsb pdb:4BX9 refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2015/05/08 2015/05/08 rogid:bm088LmFRv3w0wfvlPMFeottZkw9606 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:DWH7h6/GsUIfpB+UT3lYx0pvES8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H270 uniprotkb:Q63615 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 intact:EBI-918669 psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817278|imex:IM-24171-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 rigid:kZ0vaJmnDBEenDHmUW3IcmHOVac false myc tag:n-n green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H270 uniprotkb:Q9P253 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817278|imex:IM-24171-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rigid:kZ0vaJmnDBEenDHmUW3IcmHOVac false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P253 uniprotkb:Q9H270 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817301|imex:IM-24171-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:VjSFS6IdYRz2dJ8Ga3wBBCPsCWY false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63615 uniprotkb:Q9H270 intact:EBI-918669 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817309|imex:IM-24171-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:2Ma87EGNB9XeF0IKP0dPTvgEeE4 false green fluorescent protein tag:?-? myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15400 uniprotkb:Q9H270 intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817479|imex:IM-24171-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:lFaq26g0qeP7ObMMKexuZamQgps9606 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:QwkhL4JZD0wj3AUEKg9znzfXk5A false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P253 uniprotkb:O15400 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579 psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817489|imex:IM-24171-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N - - - figure legend:8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rogid:lFaq26g0qeP7ObMMKexuZamQgps9606 rigid:lWJ0XgbZ9qOMmD48/774EQ5UKBU false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63615 uniprotkb:Q9H270 intact:EBI-918669 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817323|imex:IM-24171-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:2Ma87EGNB9XeF0IKP0dPTvgEeE4 false green fluorescent protein tag:?-? myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63615 uniprotkb:Q9P253 intact:EBI-918669 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817351|imex:IM-24171-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rigid:tznvaOgJ/z4rsoF/G8MDbY7wubs false green fluorescent protein tag:?-? myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15400 uniprotkb:Q9H270 intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817497|imex:IM-24171-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:lFaq26g0qeP7ObMMKexuZamQgps9606 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:QwkhL4JZD0wj3AUEKg9znzfXk5A false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P253 uniprotkb:O15400 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579 psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817612|imex:IM-24171-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N - - - figure legend:8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rogid:lFaq26g0qeP7ObMMKexuZamQgps9606 rigid:lWJ0XgbZ9qOMmD48/774EQ5UKBU false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63615 uniprotkb:Q9H270 intact:EBI-918669 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817407|imex:IM-24171-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/20 rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:kZ0vaJmnDBEenDHmUW3IcmHOVac false green fluorescent protein tag:?-? myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63615 uniprotkb:Q9P253 intact:EBI-918669 intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509 psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10817407|imex:IM-24171-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange) - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/20 rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606 rigid:kZ0vaJmnDBEenDHmUW3IcmHOVac false green fluorescent protein tag:?-? ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-10817683 uniprotkb:Q63615 - intact:EBI-918669 psi-mi:vps11_cerae_protein(display_short)|psi-mi:EBI-10817683(display_long) psi-mi:vp33a_rat(display_long)|uniprotkb:Vps33a(gene name)|psi-mi:Vps33a(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-10817693|imex:IM-24171-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR001619(Sec1-like protein)|rgd:620643|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043154|interpro:IPR043155|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation) - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 - rogid:euzyw0LRw3iDq+pwOwANlEb2xIE10116 - false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O15400 intact:EBI-10817683 intact:EBI-3221827|ensembl:ENSP00000356918|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579 - psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short) psi-mi:vps11_cerae_protein(display_short)|psi-mi:EBI-10817683(display_long) psi-mi:"MI:0416"(fluorescence microscopy) Kim et al. (2001) pubmed:11382755|imex:IM-24171 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-10817700|imex:IM-24171-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079950(gene)|ensembl:ENST00000367941(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042582"(azurophil granule)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051640"(organelle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0070925"(organelle assembly)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:O15400|refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N - go:"GO:0031982"(vesicle) - - figure legend:8C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2015/05/08 2015/05/08 rogid:lFaq26g0qeP7ObMMKexuZamQgps9606 - - false ha tag:n-n - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)