#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09480 uniprotkb:P26152 intact:EBI-10686131 intact:EBI-10686157 psi-mi:acha2_chick(display_long)|uniprotkb:CHRNA2(gene name)|psi-mi:CHRNA2(display_short) psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686354|imex:IM-23926-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_990146.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR036719|interpro:IPR036734 refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 - - - figure legend:"Fig. 3 (top)"|comment:For this IP, the tissue extract was first immunodepleted of alpha3- and beta4-containing receptors before it was IPed twice with alpha2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-optic_lobe)|taxid:9031(chicken optic lobe) - 2015/02/27 2015/07/09 rogid:y59np9I4LTn/ylysyqVP56rV9BM9031 rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031 intact-crc:929F392AE2346FF3|rigid:f0OTje9Zk17v/pis1EbjlVjDd7o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09480 uniprotkb:P09484 intact:EBI-10686131 intact:EBI-10686072 psi-mi:acha2_chick(display_long)|uniprotkb:CHRNA2(gene name)|psi-mi:CHRNA2(display_short) psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686354|imex:IM-23926-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_990146.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR036719|interpro:IPR036734 interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 - - - figure legend:"Fig. 3 (top)"|comment:For this IP, the tissue extract was first immunodepleted of alpha3- and beta4-containing receptors before it was IPed twice with alpha2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-optic_lobe)|taxid:9031(chicken optic lobe) - 2015/02/27 2015/07/09 rogid:y59np9I4LTn/ylysyqVP56rV9BM9031 rogid:W8PeYpMt64vzQGyNy39VgQbSd889031 intact-crc:929F392AE2346FF3|rigid:f0OTje9Zk17v/pis1EbjlVjDd7o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09482 uniprotkb:P09484 intact:EBI-10686088|ensembl:ENSGALP00000009302 intact:EBI-10686072 psi-mi:acha4_chick(display_long)|uniprotkb:CHRNA4(gene name)|psi-mi:CHRNA4(display_short) psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686127|imex:IM-23926-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_990145.1|ensembl:ENSGALG00000005801(gene)|ensembl:ENSGALT00000009316(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734 interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 - - - figure legend:"Fig. 3 (bottom)"|comment:In Fig 3, the tissue extract was first immunodepleted of alpha3-, beta4- and alpha 5-containing receptors before it was IPed twice with beta2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-optic_lobe)|taxid:9031(chicken optic lobe) - 2015/02/27 2015/07/03 rogid:6Zi4QLM752J2YldSj21kGxfeEp09031 rogid:W8PeYpMt64vzQGyNy39VgQbSd889031 intact-crc:9DE1FF3BC64ED9C5|rigid:A4mkfEARbeNDQz8UX/hUFPZYaPU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09484 uniprotkb:P26152 intact:EBI-10686072 intact:EBI-10686157 psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym) psi-mi:acha5_chick(display_long)|uniprotkb:CHRNA5(gene name)|psi-mi:CHRNA5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686146|imex:IM-23926-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 refseq:NP_989746.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 - - - figure legend:"Fig. 1 (top)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-optic_lobe)|taxid:9031(chicken optic lobe) - 2015/02/27 2015/07/09 rogid:W8PeYpMt64vzQGyNy39VgQbSd889031 rogid:cKoywqHMQ+aI/IJUfCoqUuBflhY9031 intact-crc:604A427EAA1E17C1|rigid:Kiw+ouY7nA5pekufkHp7dSZmeHc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09484 uniprotkb:P09480 intact:EBI-10686072 intact:EBI-10686131 psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym) psi-mi:acha2_chick(display_long)|uniprotkb:CHRNA2(gene name)|psi-mi:CHRNA2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686146|imex:IM-23926-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 refseq:NP_990146.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR036719|interpro:IPR036734 - - - figure legend:"Fig. 1 (top)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-optic_lobe)|taxid:9031(chicken optic lobe) - 2015/02/27 2015/07/09 rogid:W8PeYpMt64vzQGyNy39VgQbSd889031 rogid:y59np9I4LTn/ylysyqVP56rV9BM9031 intact-crc:604A427EAA1E17C1|rigid:Kiw+ouY7nA5pekufkHp7dSZmeHc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09484 uniprotkb:P09482 intact:EBI-10686072 intact:EBI-10686088|ensembl:ENSGALP00000009302 psi-mi:achb2_chick(display_long)|uniprotkb:CHRNB2(gene name)|psi-mi:CHRNB2(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-1 chain(gene name synonym) psi-mi:acha4_chick(display_long)|uniprotkb:CHRNA4(gene name)|psi-mi:CHRNA4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686146|imex:IM-23926-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032932|refseq:NP_990144.1|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 refseq:NP_990145.1|ensembl:ENSGALG00000005801(gene)|ensembl:ENSGALT00000009316(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035094"(response to nicotine)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0050890"(cognition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734 - - - figure legend:"Fig. 1 (top)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-optic_lobe)|taxid:9031(chicken optic lobe) - 2015/02/27 2015/07/09 rogid:W8PeYpMt64vzQGyNy39VgQbSd889031 rogid:6Zi4QLM752J2YldSj21kGxfeEp09031 intact-crc:604A427EAA1E17C1|rigid:Kiw+ouY7nA5pekufkHp7dSZmeHc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26153 uniprotkb:P09481 intact:EBI-10686176 intact:EBI-10686191|ensembl:ENSGALP00000004750 psi-mi:achb4_chick(display_long)|uniprotkb:CHRNB4(gene name)|psi-mi:CHRNB4(display_short)|uniprotkb:Neuronal acetylcholine receptor non-alpha-3 chain(gene name synonym) psi-mi:acha3_chick(display_long)|uniprotkb:CHRNA3(gene name)|psi-mi:CHRNA3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balestra et al. (2000) pubmed:10908297|imex:IM-23926 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10686174|imex:IM-23926-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR018000|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR036719|interpro:IPR036734 refseq:NP_989747.1|ensembl:ENSGALG00000003014(gene)|ensembl:ENSGALT00000004759(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060084"(synaptic transmission involved in micturition)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-GGA-629587|reactome:R-GGA-629594 - - - figure legend:"Fig. 1 (bottom)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2015/02/27 2015/07/08 rogid:BDjWHvNbNBQA7rByXbrRkp1D8qk9031 rogid:C2oHMLLwSGJfe0mV0/WF06PSA989031 intact-crc:20A11D97FFA64B64|rigid:13xkVEGPy1X6+R5kcEuwLnsgDos false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)