#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:44337"	uniprotkb:P18910	intact:EBI-10093203|chebi:"CHEBI:64040"|chebi:"CHEBI:12575"	intact:EBI-7945470|uniprotkb:A1A5N8|intact:UNK-5360342|ensembl:ENSRNOP00000020307	psi-mi:"n-acetyl-l-glutamate(2-)"(display_short)|psi-mi:"CHEBI:44337"(display_long)|intact:"(S)-2-(acetylamino)pentanedioate"(synonym)|intact:acetyl-L-glutamate(synonym)|intact:N-Acetyl-L-glutamate(synonym)|intact:NAG(synonym)|intact:"(2S)-2-acetamidopentanedioate"(iupac name)	psi-mi:anpra_rat(display_long)|uniprotkb:Atrial natriuretic peptide receptor type A(gene name synonym)|uniprotkb:Guanylate cyclase A(gene name synonym)|uniprotkb:Npr1(gene name)|psi-mi:Npr1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	van et al. (2000)	imex:IM-23698|pubmed:10894551	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10061763|imex:IM-23698-1|wwpdb:1DP4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036745.1|rgd:3195|refseq:XP_006232653.1|go:"GO:0006182"(cGMP biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007168"(receptor guanylyl cyclase signaling pathway)|go:"GO:0010753"(positive regulation of cGMP-mediated signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016941"(natriuretic peptide receptor activity)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0043235"(receptor complex)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001170(Natriuretic peptide receptor, N-terminal)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR018297|interpro:IPR028082|ensembl:ENSRNOG00000014684(gene)|ensembl:ENSRNOT00000020307(transcript)|go:"GO:0001653"(peptide receptor activity)|go:"GO:0004383"(guanylate cyclase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|rcsb pdb:1DP4|rcsb pdb:1T34|rcsb pdb:3A3K|rcsb pdb:7BRG|rcsb pdb:7BRH|rcsb pdb:7BRI|rcsb pdb:7BRJ|rcsb pdb:7BRK|rcsb pdb:7BRL|reactome:R-RNO-5578768|interpro:IPR029787	-	inchi key:RFMMMVDNIPUKGG-YFKPBYRVSA-L	comment:mint|function:"Receptor for atrial natriuretic peptide (NPPA/ANF). Has guanylate cyclase activity on binding of NPPA/ANF"	figure legend:Table 1, Fig.1|3d-r-factors:"Rcryst: 19.8  Rfree: 22.5"|3d-resolution:2.0A|ligand:"NAG (CHEBI:44337)"|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/01/16	2015/01/21	-	rogid:9JEcr11NKKmpR8aSLIfXbviexK010116	intact-crc:D4D8FCF2805868AB	false	-	sufficient binding region:29..29-463..463(IPR001828)	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)