#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-2213511 uniprotkb:P17214 rnacentral:URS0000348061_559292 intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C psi-mi:tlc1_yeast_rna(display_short)|psi-mi:EBI-2213511(display_long) psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhou et al. (2000) pubmed:10688642|imex:IM-26586 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11176598|imex:IM-26586-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) sgd:S000006657(see-also) refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458 - comment:"TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase" crc64:9CF552AFDA6BDEDE figure legend:Fig2, Fig6|comment:The association is only slightly diminished in the absebce of EST2 or EST3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2015/09/10 2016/03/18 - rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292 - false - ha tag:n-n|mutation disrupting interaction:499-499,504-504,506-506|mutation decreasing interaction:465-465,466-466 - - psi-mi:"MI:0929"(northern blot) psi-mi:"MI:0929"(northern blot)