#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P29846-PRO_0000037666	uniprotkb:P36941	intact:EBI-8847394	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:p29846-pro_0000037666(display_long)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Matsumoto et al. (1997)	pubmed:8995654|imex:IM-26059	taxid:31645(hcvtw)|taxid:31645("Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9099695|imex:IM-26059-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-909718(chain-parent)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	chain-seq-start:2|chain-seq-end:191	-	figure legend:Fig. 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/27	2017/09/02	rogid:+lRB/Q1areislOqUbdQpc20G/Qc31645	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:41C0DD875EB92277|rigid:6CgYDGlCVIw39FJ0decFfPO8EMs	false	-	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P29846-PRO_0000037666	uniprotkb:P36941	intact:EBI-8847394	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:p29846-pro_0000037666(display_long)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Matsumoto et al. (1997)	pubmed:8995654|imex:IM-26059	taxid:31645(hcvtw)|taxid:31645("Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9099677|imex:IM-26059-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-909718(chain-parent)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	chain-seq-start:2|chain-seq-end:191	-	figure legend:Fig. 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/01/27	2017/09/02	rogid:+lRB/Q1areislOqUbdQpc20G/Qc31645	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:B009B77CCCBB9A4E|rigid:6CgYDGlCVIw39FJ0decFfPO8EMs	false	sufficient binding region:1-115	sufficient binding region:273-435	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29846-PRO_0000037666	uniprotkb:P36941	intact:EBI-8847394	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:p29846-pro_0000037666(display_long)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0096"(pull down)	Matsumoto et al. (1997)	pubmed:8995654|imex:IM-26059	taxid:31645(hcvtw)|taxid:31645("Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9099711|imex:IM-26059-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-909718(chain-parent)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	chain-seq-start:2|chain-seq-end:191	-	figure legend:Fig. 3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/27	2014/10/16	rogid:+lRB/Q1areislOqUbdQpc20G/Qc31645	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:64DB9099184D17D2|rigid:6CgYDGlCVIw39FJ0decFfPO8EMs	false	35s radiolabel:?-?	sufficient binding region:338-395|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P29846-PRO_0000037666	uniprotkb:P36941	intact:EBI-8847394	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:p29846-pro_0000037666(display_long)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Matsumoto et al. (1997)	pubmed:8995654|imex:IM-26059	taxid:31645(hcvtw)|taxid:31645("Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9099729|imex:IM-26059-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-909718(chain-parent)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	go:"GO:0033644"(host cell membrane)	chain-seq-start:2|chain-seq-end:191	-	figure legend:Fig. 4A and 4D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast)	-	2014/01/27	2014/10/16	rogid:+lRB/Q1areislOqUbdQpc20G/Qc31645	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:CDB75D071828DF75|rigid:6CgYDGlCVIw39FJ0decFfPO8EMs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29846-PRO_0000037666	uniprotkb:P36941	intact:EBI-8847394	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:p29846-pro_0000037666(display_long)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Matsumoto et al. (1997)	pubmed:8995654|imex:IM-26059	taxid:31645(hcvtw)|taxid:31645("Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-9105466|imex:IM-26059-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-909718(chain-parent)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	chain-seq-start:2|chain-seq-end:191	-	figure legend:Table1 and 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2014/01/27	2014/10/16	rogid:+lRB/Q1areislOqUbdQpc20G/Qc31645	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:032F4EB4E5CE5749|rigid:6CgYDGlCVIw39FJ0decFfPO8EMs	false	sufficient binding region:36-91	sufficient binding region:273-435	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)