#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NWT6	uniprotkb:Q8IY67	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2105155|uniprotkb:A6NMU4|uniprotkb:Q8IY60|uniprotkb:Q8TF24|intact:EBI-2562007|ensembl:ENSP00000479520	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ravr1_human(display_long)|uniprotkb:RAVER1(gene name)|psi-mi:RAVER1(display_short)|uniprotkb:KIAA1978(gene name synonym)|uniprotkb:Protein raver-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_597709.2|dip:DIP-46973N|ensembl:ENSG00000161847(gene)|ensembl:ENST00000615032(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3SMZ|rcsb pdb:3VF0	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:bu5ZIcFaIb6EihZAWpUflnrWL1w9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P54132	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8NB46	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1996119|uniprotkb:B1Q2K2|uniprotkb:A6NE79|ensembl:ENSP00000267116	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anr52_human(display_long)|uniprotkb:ANKRD52(gene name)|psi-mi:ANKRD52(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 52(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_775866.2|ensembl:ENSG00000139645(gene)|ensembl:ENST00000267116(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:yDxfgyMLVZlGwQW0OSokGlMkmPo9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q05823	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-8390477|uniprotkb:Q6AI46|uniprotkb:Q5W0L2|intact:MINT-7990548|ensembl:ENSP00000356530	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rn5a_human(display_long)|uniprotkb:RNASEL(gene name)|psi-mi:RNASEL(display_short)|uniprotkb:RNS4(gene name synonym)|uniprotkb:Ribonuclease L(gene name synonym)|uniprotkb:Ribonuclease 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_066956.1|dip:DIP-61367N|ensembl:ENSG00000135828(gene)|ensembl:ENST00000367559(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR010513(Ribonuclease L)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038357|interpro:IPR042745|mint:Q05823|rcsb pdb:1WDY|rcsb pdb:4G8K|rcsb pdb:4G8L|rcsb pdb:4OAU|rcsb pdb:4OAV|reactome:R-HSA-8983711|reactome:R-HSA-909733	-	-	comment:mint	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:5zeVyBXaQ84yxEU3WhFHY9Cdyns9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NVH0	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-11324738|uniprotkb:Q8N3D3|uniprotkb:Q6AWB6|uniprotkb:G5E947|uniprotkb:B4DIH6|ensembl:ENSP00000313140|ensembl:ENSP00000387331	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:exd2_human(display_long)|uniprotkb:EXD2(gene name)|psi-mi:EXD2(display_short)|uniprotkb:C14orf114(gene name synonym)|uniprotkb:EXDL2(gene name synonym)|uniprotkb:Exonuclease 3'-5' domain-like-containing protein 2(gene name synonym)|uniprotkb:3'-5' exoribonuclease EXD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001180289.1|refseq:NP_001180290.1|refseq:NP_001180291.1|refseq:NP_001180292.1|refseq:NP_060669.1|refseq:XP_005267874.1|refseq:XP_011535210.1|ensembl:ENSG00000081177(gene)|ensembl:ENST00000312994(transcript)|ensembl:ENST00000409018(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|rcsb pdb:6K17|rcsb pdb:6K18|rcsb pdb:6K19|rcsb pdb:6K1A|rcsb pdb:6K1B|rcsb pdb:6K1C|rcsb pdb:6K1D|rcsb pdb:6K1E|refseq:XP_016876910.1|dip:DIP-61996N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:Id4gHPaa70qNO9LznLBjDgkMlu09606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NWX5	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-6425205|ensembl:ENSP00000277458|uniprotkb:Q9BV15|uniprotkb:Q5SZB7	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:asb6_human(display_long)|uniprotkb:ASB6(gene name)|psi-mi:ASB6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000148331(gene)|ensembl:ENST00000277458(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037327|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001189332.1|refseq:NP_060343.1|refseq:NP_821066.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:rY7CErPA4Y+wLyfVov0JP8YS9lA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q68DC2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-7054139|ensembl:ENSP00000297837|uniprotkb:Q6P2R2|uniprotkb:Q8N9L6|uniprotkb:Q5VSL4|uniprotkb:Q5VSL3|uniprotkb:Q5VSL0|intact:MINT-8201748|uniprotkb:Q5VSL2|uniprotkb:Q68DB8|uniprotkb:A0SE62|uniprotkb:Q96D62	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anks6_human(display_long)|uniprotkb:ANKS6(gene name)|psi-mi:ANKS6(display_short)|uniprotkb:ANKRD14(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 14(gene name synonym)|uniprotkb:SAMD6(gene name synonym)|uniprotkb:SamCystin(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 6(gene name synonym)|uniprotkb:PKDR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:XP_006717061.1|ensembl:ENSG00000165138(gene)|ensembl:ENST00000353234(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0097543"(ciliary inversin compartment)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4NL9|refseq:XP_016869934.1|refseq:NP_775822.3	-	-	comment:mint	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:FQocqMZzXWSFOai/isoLAfXNkMM9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NU02	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-8464238|uniprotkb:B3KUQ0|intact:MINT-8417601|uniprotkb:Q9H6Y9|ensembl:ENSP00000367644|ensembl:ENSP00000367631	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anke1_human(display_long)|uniprotkb:ANKEF1(gene name)|psi-mi:ANKEF1(display_short)|uniprotkb:ANKRD5(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001290401.1|refseq:NP_942093.1|refseq:NP_071379.3|ensembl:ENST00000378380(transcript)|ensembl:ENST00000378392(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002110(Ankyrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR020683|interpro:IPR036770|mint:Q9NU02|ensembl:ENSG00000132623(gene)	-	-	comment:mint|comment:homomint	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:8itXXhb3BHe7mX9ll6kIt7Wacso9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O95218	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485(gene)|ensembl:ENST00000370920(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q969S3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2687480|ensembl:ENSP00000310042	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:zn622_human(display_long)|uniprotkb:ZPR9(gene name synonym)|uniprotkb:Zinc finger-like protein 9(gene name synonym)|uniprotkb:ZNF622(gene name)|psi-mi:ZNF622(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_219482.1|ensembl:ENSG00000173545(gene)|ensembl:ENST00000308683(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661|mint:Q969S3|rcsb pdb:6LQM|rcsb pdb:6LSR	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:WUzJA1E/Gz78ud7PgHYxKxUSvU49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8N5A5	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NUD5	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2954851|uniprotkb:Q3B7J3|ensembl:ENSP00000484056|uniprotkb:Q6NT79	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:zchc3_human(display_long)|uniprotkb:ZCCHC3(gene name)|psi-mi:ZCCHC3(display_short)|uniprotkb:C20orf99(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000247315(gene)|ensembl:ENST00000500893(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042509|refseq:NP_149080.2	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:7OjndwgSqExNYquAbdZ2zX2Ploc9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8WYQ9	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3937908|uniprotkb:D3DUN1|uniprotkb:Q9UFP0|uniprotkb:Q3MJD8|uniprotkb:O60324|ensembl:ENSP00000268616	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:zch14_human(display_long)|uniprotkb:ZCCHC14(gene name)|psi-mi:ZCCHC14(display_short)|uniprotkb:KIAA0579(gene name synonym)|uniprotkb:BDG-29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000140948(gene)|ensembl:ENST00000268616(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036871|interpro:IPR036875|interpro:IPR037632|interpro:IPR042344|refseq:NP_055959.1|refseq:XP_005255915.2	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:ue9awoCp5n5e5qL3YDG4kRltdgI9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q86T24	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2515625|ensembl:ENSP00000314153|ensembl:ENSP00000450969|uniprotkb:Q7Z361|uniprotkb:Q8N3P0|uniprotkb:Q8IVP6|uniprotkb:O00319|uniprotkb:B2R5U6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:kaiso_human(display_long)|uniprotkb:ZBTB33(gene name)|psi-mi:ZBTB33(display_short)|uniprotkb:KAISO(gene name synonym)|uniprotkb:ZNF348(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 33(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000177485(gene)|ensembl:ENST00000326624(transcript)|ensembl:ENST00000557385(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2LT7|rcsb pdb:3FKC|rcsb pdb:3M4T|rcsb pdb:3M8V|rcsb pdb:4F6M|rcsb pdb:4F6N|rcsb pdb:5VMU|rcsb pdb:5VMV|rcsb pdb:5VMW|rcsb pdb:5VMX|rcsb pdb:5VMY|rcsb pdb:5VMZ|rcsb pdb:6DF5|rcsb pdb:6DF8|rcsb pdb:6DF9|rcsb pdb:6DFA|rcsb pdb:6DFB|rcsb pdb:6DFC|rcsb pdb:6V8U|refseq:NP_001171671.1|refseq:NP_006768.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:nD+3FCTCYxUrXZXpBW5Co1V0CHc9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9BQA1	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:0q4wunYtHalObC8r1wphhelIpr49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q96MT7-2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-12502474|ensembl:ENSP00000377428	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:q96mt7-2(display_long)|uniprotkb:CFAP44(gene name)|psi-mi:CFAP44(display_short)|uniprotkb:WD repeat-containing protein 52(gene name synonym)|uniprotkb:WDR52(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000206530(gene)|ensembl:ENST00000393845(transcript)|intact:EBI-12551219(isoform-parent)|uniprotkb:Q96MT7-2(isoform-parent)	-	-	isoform-comment:Contains a phosphoserine at position 1083.	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:kNq3QEFHInBvKw4DjNoWPm2J/7k9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9P0L0	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q14157	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UPQ9	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-947158|uniprotkb:B0QY78|uniprotkb:Q5TH52|uniprotkb:Q8TBX2|uniprotkb:B4DGC0|uniprotkb:B0QY73|ensembl:ENSP00000401946	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tnr6b_human(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001020014.1|refseq:NP_001155973.1|refseq:NP_055903.2|dip:DIP-29624N|ensembl:ENSG00000100354(gene)|ensembl:ENST00000454349(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR033500|interpro:IPR034925|interpro:IPR035979|mint:Q9UPQ9|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:A4yGG9Gt++0QN+6jFzfhWVYN+Dw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9H2K2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-4398527|uniprotkb:Q9H8F2|uniprotkb:Q9HAS4|uniprotkb:B2RBD3|ensembl:ENSP00000360689	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tnks2_human(display_long)|uniprotkb:TNKS2(gene name)|psi-mi:TNKS2(display_short)|uniprotkb:PARP5B(gene name synonym)|uniprotkb:TANK2(gene name synonym)|uniprotkb:TNKL(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5B(gene name synonym)|uniprotkb:TNKS-2(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase 2(gene name synonym)|uniprotkb:Tankyrase II(gene name synonym)|uniprotkb:Tankyrase-like protein(gene name synonym)|uniprotkb:Tankyrase-related protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 6(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-2(gene name synonym)|uniprotkb:Tankyrase-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_079511.1|dip:DIP-42098N|rcsb pdb:3P0Q|rcsb pdb:3TWQ|rcsb pdb:3TWR|rcsb pdb:3TWS|rcsb pdb:3TWT|rcsb pdb:3TWU|rcsb pdb:3TWV|rcsb pdb:3TWW|rcsb pdb:3TWX|rcsb pdb:3U9H|rcsb pdb:3U9Y|rcsb pdb:3UA9|rcsb pdb:3W51|rcsb pdb:4AVU|rcsb pdb:4AVW|rcsb pdb:4BFP|rcsb pdb:4BJ9|rcsb pdb:4BJB|rcsb pdb:4BJC|rcsb pdb:4BS4|rcsb pdb:4BU3|rcsb pdb:4BU5|rcsb pdb:4BU6|rcsb pdb:4BU7|rcsb pdb:4BU8|rcsb pdb:4BU9|rcsb pdb:4BUA|rcsb pdb:4BUD|rcsb pdb:4BUE|rcsb pdb:4BUF|rcsb pdb:4BUI|rcsb pdb:4BUS|rcsb pdb:4BUT|rcsb pdb:4BUU|rcsb pdb:4BUV|rcsb pdb:4BUW|rcsb pdb:4BUX|rcsb pdb:4BUY|rcsb pdb:4HKI|rcsb pdb:4HKK|rcsb pdb:4HKN|ensembl:ENSG00000107854(gene)|ensembl:ENST00000371627(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9H2K2|rcsb pdb:2Y0I|rcsb pdb:3KR7|rcsb pdb:3KR8|rcsb pdb:3MHJ|rcsb pdb:3MHK|rcsb pdb:3P0N|rcsb pdb:3P0P|rcsb pdb:6TKP|rcsb pdb:6TKQ|rcsb pdb:6TKR|rcsb pdb:6TKS|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:6TKN|rcsb pdb:4HL5|rcsb pdb:4HLF|rcsb pdb:4HLG|rcsb pdb:4HLH|rcsb pdb:4HLK|rcsb pdb:4HLM|rcsb pdb:4HMH|rcsb pdb:4HYF|rcsb pdb:4IUE|rcsb pdb:4J1Z|rcsb pdb:4J21|rcsb pdb:4J22|rcsb pdb:4J3L|rcsb pdb:4J3M|rcsb pdb:4KZL|rcsb pdb:4KZQ|rcsb pdb:4KZU|rcsb pdb:4L09|rcsb pdb:4L0B|rcsb pdb:4L0I|rcsb pdb:4L0T|rcsb pdb:4L0V|rcsb pdb:4L10|rcsb pdb:4L2F|rcsb pdb:4L2G|rcsb pdb:4L2K|rcsb pdb:4L31|rcsb pdb:4L32|rcsb pdb:4L33|rcsb pdb:4L34|rcsb pdb:4M7B|rcsb pdb:4PML|rcsb pdb:4PNL|rcsb pdb:4PNM|rcsb pdb:4PNN|rcsb pdb:4PNQ|rcsb pdb:4PNR|rcsb pdb:4PNS|rcsb pdb:4PNT|rcsb pdb:4TJU|rcsb pdb:4TJW|rcsb pdb:4TJY|rcsb pdb:4TK0|rcsb pdb:4TK5|rcsb pdb:4TKF|rcsb pdb:4TKG|rcsb pdb:4TKI|rcsb pdb:4UFU|rcsb pdb:4UFY|rcsb pdb:4UHG|rcsb pdb:4UI3|rcsb pdb:4UI4|rcsb pdb:4UI5|rcsb pdb:4UI6|rcsb pdb:4UI7|rcsb pdb:4UI8|rcsb pdb:4UVL|rcsb pdb:4UVN|rcsb pdb:4UVO|rcsb pdb:4UVP|rcsb pdb:4UVS|rcsb pdb:4UVT|rcsb pdb:4UVU|rcsb pdb:4UVV|rcsb pdb:4UVW|rcsb pdb:4UVX|rcsb pdb:4UVY|rcsb pdb:4UVZ|rcsb pdb:4UX4|rcsb pdb:4W5I|rcsb pdb:4Z68|rcsb pdb:5ADQ|rcsb pdb:5ADR|rcsb pdb:5ADS|rcsb pdb:5ADT|rcsb pdb:5AEH|rcsb pdb:5AKU|rcsb pdb:5AKW|rcsb pdb:5AL1|rcsb pdb:5AL2|rcsb pdb:5AL3|rcsb pdb:5AL4|rcsb pdb:5AL5|rcsb pdb:5BXO|rcsb pdb:5BXU|rcsb pdb:5C5P|rcsb pdb:4L0S|rcsb pdb:5C5Q|rcsb pdb:5C5R|rcsb pdb:5DCZ|rcsb pdb:5FPF|rcsb pdb:5FPG|rcsb pdb:5JRT|rcsb pdb:5NOB|rcsb pdb:5NSP|rcsb pdb:5NUT|rcsb pdb:5OWS|rcsb pdb:5OWT|rcsb pdb:6TG4|rcsb pdb:6TKM	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:pf0mQR/in4ShtYc1xmCF042/v/A9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O95271	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1105254|uniprotkb:O95272|uniprotkb:Q4G0F2|intact:EBI-28985643|ensembl:ENSP00000311579	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tnks1_human(display_long)|uniprotkb:TNKS(gene name)|psi-mi:TNKS(display_short)|uniprotkb:PARP5A(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:TIN1(gene name synonym)|uniprotkb:TINF1(gene name synonym)|uniprotkb:TNKS1(gene name synonym)|uniprotkb:Tankyrase I(gene name synonym)|uniprotkb:TNKS-1(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5A(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 5(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-1(gene name synonym)|uniprotkb:Tankyrase-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_003738.2|rcsb pdb:5JHQ|rcsb pdb:5JTI|rcsb pdb:5JU5|rcsb pdb:5KNI|rcsb pdb:6QXU|rcsb pdb:6URQ|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:5GP7|ensembl:ENSP00000311579|ensembl:ENSG00000173273(gene)|ensembl:ENST00000310430(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051028"(mRNA transport)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904743"(negative regulation of telomeric DNA binding)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|mint:O95271|rcsb pdb:2RF5|rcsb pdb:3UDD|rcsb pdb:3UH2|rcsb pdb:3UH4|rcsb pdb:4DVI|rcsb pdb:4I9I|go:"GO:0016055"(Wnt signaling pathway)|rcsb pdb:4K4F|rcsb pdb:4KRS|rcsb pdb:4LI6|rcsb pdb:4LI7|rcsb pdb:4LI8|rcsb pdb:4MSG|rcsb pdb:4MSK|rcsb pdb:4MT9|rcsb pdb:4N3R|rcsb pdb:4N4V|rcsb pdb:4OA7|rcsb pdb:4TOR|rcsb pdb:4TOS|rcsb pdb:4U6A|rcsb pdb:4UUH|rcsb pdb:4UW1|rcsb pdb:4K4E|rcsb pdb:4W5S|rcsb pdb:4W6E|rcsb pdb:5EBT|rcsb pdb:5ECE|rcsb pdb:5ETY|dip:DIP-36652N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:0WKEfg5OMAISQutoJb2w+hBfmOU9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UM00	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1051217|uniprotkb:O75545|uniprotkb:Q9BZS3|uniprotkb:Q9BZU8|uniprotkb:B2REA0|ensembl:ENSP00000480514|uniprotkb:J9JIE6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tmco1_human(display_long)|uniprotkb:Transmembrane and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Xenogeneic cross-immune protein PCIA3(gene name synonym)|uniprotkb:Transmembrane and coiled-coil domains protein 4(gene name synonym)|uniprotkb:TMCO1(gene name)|psi-mi:TMCO1(display_short)|uniprotkb:PNAS-10(orf name)|uniprotkb:PNAS-136(orf name)|uniprotkb:UNQ151/PRO177(orf name)|uniprotkb:TMCC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_061899.2|ensembl:ENSG00000143183(gene)|ensembl:ENST00000612311(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006983"(ER overload response)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0043022"(ribosome binding)|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008559(Protein of unknown function DUF841, eukaryotic)|rcsb pdb:6W6L	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:AGRI6UgUEOjrVCi0laVQPtfaHRU9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9Y4G6	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1220811|uniprotkb:A6NLB8|ensembl:ENSP00000453508	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tln2_human(display_long)|uniprotkb:TLN2(gene name)|psi-mi:TLN2(display_short)|uniprotkb:KIAA0320(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_055874.2|refseq:XP_016878157.1|dip:DIP-17039N|ensembl:ENSG00000171914(gene)|ensembl:ENST00000561311(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y4G6|rcsb pdb:6U4K	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:/vkImDHugUJnyPtaJs/XfDyhXYo9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q99081	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q15370	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q15369	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q92844	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-356349|uniprotkb:Q92885|uniprotkb:D3DPB5|ensembl:ENSP00000259075|ensembl:ENSP00000376505|uniprotkb:Q7Z4J6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tank_human(display_long)|uniprotkb:TANK(gene name)|psi-mi:TANK(display_short)|uniprotkb:ITRAF(gene name synonym)|uniprotkb:TRAF2(gene name synonym)|uniprotkb:TRAF-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001186064.1|refseq:NP_004171.2|refseq:NP_597841.1|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR024581|interpro:IPR039669|interpro:IPR041641|mint:Q92844|rcsb pdb:1KZZ|rcsb pdb:1L0A|rcsb pdb:5H10|reactome:R-HSA-9013973|reactome:R-HSA-933541|reactome:R-HSA-936964|go:"GO:1903003"(positive regulation of protein deubiquitination)|ensembl:ENST00000259075(transcript)|ensembl:ENST00000392749(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071479"(cellular response to ionizing radiation)|ensembl:ENSG00000136560(gene)|refseq:XP_016858585.1|refseq:XP_016858586.1|dip:DIP-27516N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:B6PUVX1PZ5XmFszyF0tRSwfbb4M9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8WXH0	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2372294|uniprotkb:Q540G1|uniprotkb:Q8N1S3|uniprotkb:Q8NF49|uniprotkb:Q8TER7|uniprotkb:Q8WWW3|uniprotkb:Q8WWW4|uniprotkb:Q8WWW5|uniprotkb:Q8WXH1|uniprotkb:Q9NU50|uniprotkb:Q9UFQ4|uniprotkb:Q9Y2L4|uniprotkb:Q9Y4R1|uniprotkb:Q86YP9|uniprotkb:B4DND7|uniprotkb:B4DPR6|uniprotkb:I6XXQ5|ensembl:ENSP00000341781	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:syne2_human(display_long)|uniprotkb:SYNE2(gene name)|psi-mi:SYNE2(display_short)|uniprotkb:KIAA1011(gene name synonym)|uniprotkb:NUA(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSP00000344528|ensembl:ENSP00000341781|ensembl:ENST00000358025|ensembl:ENSP00000350719|ensembl:ENST00000458046|ensembl:ENSP00000391937|ensembl:ENST00000555002|ensembl:ENSP00000450831|ensembl:ENST00000341472|refseq:NP_055995.4|refseq:NP_878914.1|refseq:NP_878917.1|refseq:NP_878918.2|dip:DIP-53409N|ensembl:ENSG00000054654(gene)|ensembl:ENST00000344113(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005925"(focal adhesion)|go:"GO:0007097"(nuclear migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR030266|interpro:IPR036872|rcsb pdb:4DXS|rcsb pdb:4FI9|rcsb pdb:6XF1|reactome:R-HSA-1221632	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:wLHWOXR+dUHkcs93g+F2av/9wm49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UNL2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1043938|uniprotkb:Q549M4|ensembl:ENSP00000265044|uniprotkb:B2R7D0|uniprotkb:D3DNK5|uniprotkb:B4E2P2	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ssrg_human(display_long)|uniprotkb:Signal sequence receptor subunit gamma(gene name synonym)|uniprotkb:SSR3(gene name)|psi-mi:SSR3(display_short)|uniprotkb:TRAPG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_009038.1|ensembl:ENSG00000114850(gene)|ensembl:ENST00000265044(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009779(Translocon-associated, gamma subunit)|mint:Q9UNL2|reactome:R-HSA-1799339|refseq:NP_001295126.1|refseq:NP_001295133.1|refseq:NP_001295134.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:Fb918T41oaTpc+kzNIygp1h1tlo9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9Y2K2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1181460|intact:EBI-1384133|uniprotkb:Q59FY2|uniprotkb:Q5M9N1|uniprotkb:Q6P3R6|uniprotkb:Q8IYM8|uniprotkb:Q9HA50|uniprotkb:H0Y494|uniprotkb:J3KPC8|ensembl:ENSP00000364449|uniprotkb:A1A5A8	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:sik3_human(display_long)|uniprotkb:QSK(gene name synonym)|uniprotkb:KIAA0999(gene name synonym)|uniprotkb:SIK3(gene name)|psi-mi:SIK3(display_short)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:L19(orf name)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_079440.3|ensembl:ENSG00000160584(gene)|ensembl:ENST00000375300(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672|refseq:NP_001268678.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:YZTDZCOcd7R9N57N7J/iFkCxzwo9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P60468	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O43159	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2008793|uniprotkb:Q7KZ78|uniprotkb:Q9BVM6|ensembl:ENSP00000254605	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rrp8_human(display_long)|uniprotkb:RRP8(gene name)|psi-mi:RRP8(display_short)|uniprotkb:hucep-1(orf name)|uniprotkb:NML(gene name synonym)|uniprotkb:Nucleomethylin(gene name synonym)|uniprotkb:KIAA0409(gene name synonym)|uniprotkb:Cerebral protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_056139.1|dip:DIP-46686N|ensembl:ENSG00000132275(gene)|ensembl:ENST00000254605(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR007823(Methyltransferase-related)|interpro:IPR023576|interpro:IPR029063|interpro:IPR042036|mint:O43159|rcsb pdb:2ZFU|reactome:R-HSA-427359	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:SNRPocKaPjMCXSLDe1ytWlUWYTw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P62847	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P62841	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-372635|uniprotkb:Q3KRA1|uniprotkb:P11174|uniprotkb:A5D8V9|uniprotkb:Q9UDC2|ensembl:ENSP00000467466	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rs15_human(display_long)|uniprotkb:RIG protein(gene name synonym)|uniprotkb:RPS15(gene name)|psi-mi:RPS15(display_short)|uniprotkb:RIG(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001009.1|mint:P62841|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|ensembl:ENSG00000115268(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|ensembl:ENST00000592588(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0097421"(liver regeneration)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR023575|rcsb pdb:6ZVH|rcsb pdb:6ZMT|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6ZMW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:lJJOew1txuTwFlhKu4Z+AkPS5H09606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q5VT52	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P61927	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2105843|uniprotkb:P02403|uniprotkb:Q6IBB4|uniprotkb:Q99883|uniprotkb:B2R4H2|ensembl:ENSP00000274242	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rl37_human(display_long)|uniprotkb:Large ribosomal subunit protein eL37(gene name synonym)|uniprotkb:RPL37(gene name)|psi-mi:RPL37(display_short)|uniprotkb:G1.16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_000988.1|ensembl:ENSG00000145592(gene)|ensembl:ENST00000274242(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001569(Ribosomal protein L37e)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR018267|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:0WNZ8lgxYeW91kmXUr2VQG1ULZw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P61353	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P57078	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q7L0Y3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q04206	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9HCJ3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-11285589|uniprotkb:Q6P141|uniprotkb:Q9NPV7|ensembl:ENSP00000294428	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ravr2_human(display_long)|uniprotkb:RAVER2(gene name)|psi-mi:RAVER2(display_short)|uniprotkb:KIAA1579(gene name synonym)|uniprotkb:Protein raver-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_060681.2|refseq:XP_006710801.2|ensembl:ENSG00000162437(gene)|ensembl:ENST00000294428(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034636|interpro:IPR035979|rcsb pdb:1WG1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:tzvmxjtk7jPFL2U3FvphfCPvxII9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q2TAL8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2798044|uniprotkb:Q8TEA5|uniprotkb:Q4G0F7|uniprotkb:Q7L621|ensembl:ENSP00000350094|ensembl:ENSP00000378830|ensembl:ENSP00000412890	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:qric1_human(display_long)|uniprotkb:QRICH1(gene name)|psi-mi:QRICH1(display_short)|uniprotkb:Glutamine-rich protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001307509.1|refseq:NP_001307510.1|refseq:NP_001307511.1|refseq:NP_001307512.1|refseq:NP_001307513.1|refseq:NP_001307514.1|refseq:XP_011532165.1|refseq:NP_060200.2|refseq:NP_942581.1|ensembl:ENSG00000198218(gene)|ensembl:ENST00000357496(transcript)|ensembl:ENST00000395443(transcript)|ensembl:ENST00000424300(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0140467"(integrated stress response signaling)|interpro:IPR021893	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:lZutsiEMc3Fpej5M2vhosiQZnoA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O00487	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UNM6	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:iOxE62MMeGx+aqsrir/LukJqeho9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O75832	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P62195	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	-	crc64:29C6410C4A85A7F7	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P35998	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q5H9R7	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UPN7	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O15355	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P62875	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-359527|ensembl:ENSP00000324124|ensembl:ENSP00000432807|uniprotkb:P52436|uniprotkb:Q6FHX3	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rpab5_human(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym)|uniprotkb:RPB10 homolog(gene name synonym)|uniprotkb:RNA polymerase II 7.6 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000177700(gene)|ensembl:ENST00000322028(transcript)|ensembl:ENST00000534030(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|mint:P62875|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|refseq:NP_066951.1|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-75955|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-203927|dip:DIP-32960N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P30876	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q4KWH8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-4397439|uniprotkb:Q29RV9|uniprotkb:Q4KWH9|uniprotkb:Q68CN0|uniprotkb:Q86XK4|uniprotkb:Q9H9U2|uniprotkb:Q9UPT3|ensembl:ENSP00000345988	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:plch1_human(display_long)|uniprotkb:PLCH1(gene name)|psi-mi:PLCH1(display_short)|uniprotkb:KIAA1069(gene name synonym)|uniprotkb:PLCL3(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-eta-1(gene name synonym)|uniprotkb:Phospholipase C-eta-1(gene name synonym)|uniprotkb:Phospholipase C-like protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:XP_016861418.1|refseq:NP_001124432.1|refseq:NP_001124433.1|refseq:NP_055811.1|ensembl:ENSG00000114805(gene)|ensembl:ENST00000340059(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028392|interpro:IPR035892|reactome:R-HSA-1855204	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:1s93Atnty4Dtv/L0phvC7bhtJDg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O60733	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-12089905|ensembl:ENSP00000333142|ensembl:ENSP00000499555|ensembl:ENSP00000499665|ensembl:ENSP00000499712|uniprotkb:A8K597|uniprotkb:B0QYE8|uniprotkb:O75645|uniprotkb:Q8N452|uniprotkb:Q9UG29|uniprotkb:Q9UIT0|uniprotkb:Q9Y671	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:plpl9_human(display_long)|uniprotkb:PLA2G6(gene name)|psi-mi:PLA2G6(display_short)|uniprotkb:Group VI phospholipase A2(gene name synonym)|uniprotkb:Intracellular membrane-associated calcium-independent phospholipase A2 beta(gene name synonym)|uniprotkb:PLPLA9(gene name synonym)|uniprotkb:Patatin-like phospholipase domain-containing protein 9(gene name synonym)|uniprotkb:2-lysophosphatidylcholine acylhydrolase(gene name synonym)|uniprotkb:Palmitoyl-CoA hydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000184381(gene)|ensembl:ENST00000332509(transcript)|ensembl:ENST00000660610(transcript)|ensembl:ENST00000663895(transcript)|ensembl:ENST00000667521(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|interpro:IPR002110(Ankyrin)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482839|reactome:R-HSA-2029485|reactome:R-HSA-6811436|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042311"(vasodilation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046338"(phosphatidylethanolamine catabolic process)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046473"(phosphatidic acid metabolic process)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|refseq:NP_001004426.1|refseq:NP_001186491.1|refseq:NP_003551.2|refseq:XP_005261821.1|refseq:XP_005261822.1|refseq:XP_005261823.1|refseq:XP_006724395.1|refseq:XP_016884470.1|refseq:XP_016884471.1|refseq:XP_016884477.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:3kvF2S7ye5ubo/5f3O0Oa+tuDCI9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8IZ21	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3938822|uniprotkb:Q9H6X0|uniprotkb:Q8N384|uniprotkb:Q6NUN6|uniprotkb:Q9H8W6|uniprotkb:D3DPM3|uniprotkb:A2APK6|uniprotkb:Q9H395|uniprotkb:Q68DD4|uniprotkb:B9ZVW0|ensembl:ENSP00000362945	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:phar4_human(display_long)|uniprotkb:PHACTR4(gene name)|psi-mi:PHACTR4(display_short)|uniprotkb:PRO2963(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000204138(gene)|ensembl:ENST00000373839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061386"(closure of optic fissure)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|interpro:IPR004018(RPEL repeat)|interpro:IPR029984|refseq:NP_001041648.1|refseq:NP_076412.3|refseq:XP_016857657.1|refseq:XP_016857662.1|dip:DIP-47323N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:RaPU7amt8Ztkr4p8+PMGSs5Pw4I9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P08237	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-514788|uniprotkb:Q16814|uniprotkb:Q16815|uniprotkb:J3KNX3|uniprotkb:Q6ZTT1|ensembl:ENSP00000309438|ensembl:ENSP00000352842|ensembl:ENSP00000446945|ensembl:ENSP00000448253|ensembl:ENSP00000449426|ensembl:ENSP00000450369	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:pfkam_human(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:PFKM(gene name)|psi-mi:PFKM(display_short)|uniprotkb:6-phosphofructokinase type A(gene name synonym)|uniprotkb:PFKX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_000280.1|refseq:NP_001160158.1|refseq:NP_001160159.1|refseq:NP_001160160.1|refseq:XP_016874957.1|refseq:XP_005269034.1|refseq:XP_005269035.1|refseq:XP_005269036.1|refseq:XP_011536790.1|ensembl:ENSG00000152556(gene)|ensembl:ENST00000312352(transcript)|ensembl:ENST00000359794(transcript)|ensembl:ENST00000547587(transcript)|ensembl:ENST00000550345(transcript)|ensembl:ENST00000550924(transcript)|ensembl:ENST00000551339(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P08237|rcsb pdb:4OMT|reactome:R-HSA-70171	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:tB7V3jdmnyITZLPqyAYjrTWo/UE9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8N3A8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-8796778|ensembl:ENSP00000281631|ensembl:ENSP00000422217|uniprotkb:Q9H754|uniprotkb:Q3KRB7|uniprotkb:Q6DHZ1	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:parp8_human(display_long)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 16(gene name synonym)|uniprotkb:PARP8(gene name)|psi-mi:PARP8(display_short)|uniprotkb:Poly [ADP-ribose] polymerase 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|mint:Q8N3A8|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|go:"GO:0070213"(protein auto-ADP-ribosylation)|ensembl:ENSG00000151883(gene)|ensembl:ENST00000281631(transcript)|ensembl:ENST00000505697(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0006471"(protein ADP-ribosylation)|refseq:XP_011541934.2|refseq:XP_011541933.1|refseq:NP_001171526.1|refseq:NP_001171527.1|refseq:NP_078891.2	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:40j9kPtn+p1lGYBXWsL+a6aKcyo9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9BXW6	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9H857	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-359244|uniprotkb:O95888|uniprotkb:Q96C80|uniprotkb:Q9H9Z8|uniprotkb:C9JTZ6|uniprotkb:E9PAL9|intact:EBI-11044897|ensembl:ENSP00000302468	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:nt5d2_human(display_long)|uniprotkb:NT5DC2(gene name)|psi-mi:NT5DC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001127703.1|refseq:NP_075059.1|refseq:XP_005265463.1|refseq:XP_006713368.1|ensembl:ENSG00000168268(gene)|ensembl:ENST00000307076(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:nfT/9N1bWVadX70eY1G0GS9pS9U9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UM47	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q04721	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001186930.1|refseq:NP_077719.2|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046849"(bone remodeling)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072104"(glomerular capillary formation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1990705"(cholangiocyte proliferation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001204"(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0035622"(intrahepatic bile duct development)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022336|interpro:IPR010660(Notch, NOD region)|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|ensembl:ENSG00000134250(gene)|ensembl:ENST00000256646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001947"(heart looping)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035264"(multicellular organism growth)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9Y3T9	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O00221	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-355098|uniprotkb:Q5T9V9|intact:EBI-28973237|ensembl:ENSP00000275015	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ikbe_human(display_long)|uniprotkb:IKBE(gene name synonym)|uniprotkb:NFKBIE(gene name)|psi-mi:NFKBIE(display_short)|uniprotkb:I-kappa-B-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_004547.2|ensembl:ENSP00000275015|ensembl:ENST00000275015(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000146232(gene)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1169091|go:"GO:0005829"(cytosol)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|dip:DIP-27533N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:5TEjEGv4jKRrWPpk6jTR+LF97zA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P25963	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q00653	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-307326|uniprotkb:Q04860|uniprotkb:Q9BU75|uniprotkb:Q9H471|uniprotkb:Q9H472|uniprotkb:D3DR83|intact:EBI-28985232|ensembl:ENSP00000358983|ensembl:ENSP00000499294|uniprotkb:A8K9D9	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:nfkb2_human(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001070962.1|refseq:NP_002493.3|refseq:NP_001248332.1|ensembl:ENSG00000077150(gene)|ensembl:ENST00000369966(transcript)|ensembl:ENST00000661543(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|interpro:IPR020683|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q00653|rcsb pdb:1A3Q|rcsb pdb:2D96|go:"GO:0048511"(rhythmic process)|rcsb pdb:3DO7|rcsb pdb:4OT9|rcsb pdb:5ZMC|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-3214841|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-5603029|interpro:IPR002909(Cell surface receptor IPT/TIG)|reactome:R-HSA-5607761|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|reactome:R-HSA-5676590|interpro:IPR011539(Rel homology)|reactome:R-HSA-844456|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-HSA-933542|reactome:R-HSA-9660826|refseq:NP_001275653.1|ensembl:ENST00000189444|ensembl:ENSP00000189444|ensembl:ENSP00000358983|ensembl:ENST00000428099|ensembl:ENSP00000410256|ensembl:ENST00000652277|ensembl:ENSP00000498308|ensembl:ENSP00000499294|refseq:NP_001309863.1|refseq:NP_001309864.1|dip:DIP-24239N|dip:DIP-27535N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:bGZ4DuEhX8eCNtkuMCJnh8PCcEI9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9P032	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9Y6Q9	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9HCH0	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3437824|uniprotkb:Q96HX2|uniprotkb:Q2TB26|uniprotkb:Q8N4W1|uniprotkb:Q71RH1|intact:EBI-28973751|ensembl:ENSP00000337998	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:nck5l_human(display_long)|uniprotkb:NCKAP5L(gene name)|psi-mi:NCKAP5L(display_short)|uniprotkb:KIAA1602(gene name synonym)|uniprotkb:FP1193(orf name)|uniprotkb:CEP169(gene name synonym)|uniprotkb:Centrosomal protein of 169 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSP00000337998|refseq:NP_001032895.2|ensembl:ENSG00000167566(gene)|ensembl:ENST00000335999(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0035371"(microtubule plus-end)|interpro:IPR026163|interpro:IPR032769	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:N7oAmkE9JcRKPqn3/EePy7FAqfo9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P41227	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-747693|uniprotkb:A6NM98|ensembl:ENSP00000417763	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:naa10_human(display_long)|uniprotkb:ARD1(gene name synonym)|uniprotkb:NAA10(gene name)|psi-mi:NAA10(display_short)|uniprotkb:TE2(gene name synonym)|uniprotkb:NatA catalytic subunit Naa10(gene name synonym)|uniprotkb:ARD1A(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001243048.1|refseq:NP_003482.1|ensembl:ENST00000464845(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006473"(protein acetylation)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|go:"GO:2000719"(negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|ensembl:ENSG00000102030(gene)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:P41227|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:h9fpQmX5wai9LCuW0bgwlDJQ8R49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NZJ7	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-297455|ensembl:ENSP00000362730|uniprotkb:Q6PK60|uniprotkb:Q6UX45|uniprotkb:Q7L465|uniprotkb:Q9BW23|uniprotkb:Q9NZR6|uniprotkb:Q9UJZ5|uniprotkb:B2RCE3|uniprotkb:A8KAX5	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:mtch1_human(display_long)|uniprotkb:Presenilin-associated protein(gene name synonym)|uniprotkb:CGI-64(orf name)|uniprotkb:MTCH1(gene name)|psi-mi:MTCH1(display_short)|uniprotkb:PSAP(gene name synonym)|uniprotkb:UNQ1871/PRO4314(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000137409(gene)|ensembl:ENST00000373627(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045161"(neuronal ion channel clustering)|interpro:IPR018108|interpro:IPR023395|mint:Q9NZJ7|refseq:NP_055156.1|refseq:NP_001258570.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:I0J5CxSiLB4OS6mhqwygLq389xY9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8TE76	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3940432|uniprotkb:Q5JUK7|uniprotkb:Q96MZ2|uniprotkb:Q9HAI7|intact:EBI-28969055|ensembl:ENSP00000347821|uniprotkb:A1YR23|uniprotkb:A1YR24|uniprotkb:H7BXF1	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:morc4_human(display_long)|uniprotkb:MORC4(gene name)|psi-mi:MORC4(display_short)|uniprotkb:ZCWCC2(gene name synonym)|uniprotkb:Zinc finger CW-type coiled-coil domain protein 2(gene name synonym)|uniprotkb:ZCW4(gene name synonym)|uniprotkb:Zinc finger CW-type domain protein 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENST00000255495|ensembl:ENSP00000255495|ensembl:ENSP00000347821|ensembl:ENSG00000133131(gene)|ensembl:ENST00000355610(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036890|interpro:IPR041006|mint:Q8TE76|rcsb pdb:7K7T|refseq:NP_078933.3|refseq:NP_001078823.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:4ZXYEyXqgZ18LMwuAgPTsqRtPgw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q5TCX8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1057380|uniprotkb:Q5TCX7|uniprotkb:Q5TCX9|uniprotkb:Q8WWN1|uniprotkb:Q8WWN2|uniprotkb:Q96JM1|uniprotkb:B2RN34|ensembl:ENSP00000355583|uniprotkb:A0A1W2PKR9|uniprotkb:X6R610	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:m3k21_human(display_long)|uniprotkb:MAP3K21(gene name)|psi-mi:MAP3K21(display_short)|uniprotkb:KIAA1804(gene name synonym)|uniprotkb:MLK4(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase MLK4(gene name synonym)|uniprotkb:Mixed lineage kinase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_115811.2|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036028|rcsb pdb:4UYA|go:"GO:0004709"(MAP kinase kinase kinase activity)|ensembl:ENSG00000143674(gene)|ensembl:ENST00000366624(transcript)|go:"GO:0004672"(protein kinase activity)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:xab7z9eHacjAYpzsNgh8MTcndfw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q15773	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q96AX9	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2130249|uniprotkb:B4DZ57|uniprotkb:J3KNZ7|uniprotkb:A2AGM5|uniprotkb:A2AGM6|uniprotkb:B3KV93|uniprotkb:B3KVF4|uniprotkb:Q7Z437|uniprotkb:Q8IY62|uniprotkb:Q8N786|uniprotkb:Q8N897|uniprotkb:Q8N8R2|uniprotkb:Q8N911|uniprotkb:Q8NB36|uniprotkb:Q8NCY1|uniprotkb:Q8NG59|uniprotkb:Q8NG60|uniprotkb:Q8NG61|uniprotkb:Q8NI59|uniprotkb:Q8WYN1|intact:EBI-11116994|uniprotkb:B3KXY1|uniprotkb:E9PGU1|uniprotkb:E9PHQ1|uniprotkb:F8WA73|intact:EBI-28979050	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:mib2_human(display_long)|uniprotkb:MIB2(gene name)|psi-mi:MIB2(display_short)|uniprotkb:SKD(gene name synonym)|uniprotkb:ZZANK1(gene name synonym)|uniprotkb:Mind bomb homolog 2(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 1(gene name synonym)|uniprotkb:Skeletrophin(gene name synonym)|uniprotkb:Novel zinc finger protein(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 002N(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001164157.1|refseq:NP_001164158.1|refseq:NP_001164159.1|refseq:NP_001164160.1|refseq:NP_543151.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR010606(Mib-herc2)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR036770|ensembl:ENST00000378712|ensembl:ENSP00000367984|ensembl:ENSG00000197530|reactome:R-HSA-983168|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:5ExYcfCt7m+bIeZiCCZ0jk0jHOc9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O43318	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q7L5Y9	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-10984762|ensembl:ENSP00000302830|uniprotkb:O95285|uniprotkb:Q5JB54|uniprotkb:Q6ZRD6|uniprotkb:Q9NW84|uniprotkb:Q9H9Z4|uniprotkb:Q9BQ11|uniprotkb:Q9H9V6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:maea_human(display_long)|uniprotkb:MAEA(gene name)|psi-mi:MAEA(display_short)|uniprotkb:Cell proliferation-inducing gene 5 protein(gene name synonym)|uniprotkb:EMP(gene name synonym)|uniprotkb:Erythroblast macrophage protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 10 protein(gene name synonym)|uniprotkb:Macrophage erythroblast attacher(gene name synonym)|uniprotkb:P44EMLP(gene name synonym)|uniprotkb:HLC10(orf name)|uniprotkb:PIG5(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001017405.1|refseq:NP_001284360.1|refseq:NP_005873.2|ensembl:ENSG00000090316(gene)|ensembl:ENST00000303400(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR027714|interpro:IPR044063|mint:Q7L5Y9	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:8eoZgqL1bgRlGgQ3YiJDejdFWtk9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9BRK4	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P83369	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2626024|uniprotkb:A0AVQ1|uniprotkb:Q7Z7P0|uniprotkb:Q8N975|ensembl:ENSP00000286307	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:lsm11_human(display_long)|uniprotkb:LSM11(gene name)|psi-mi:LSM11(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_775762.1|ensembl:ENSG00000155858(gene)|ensembl:ENST00000286307(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016604"(nuclear body)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034109|interpro:IPR039267|rcsb pdb:6V4X|reactome:R-HSA-111367|reactome:R-HSA-73856|reactome:R-HSA-77588	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:G1rWuaQHAPeHEf3rvzT/XkqvaYk9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9ULH0	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-716681|uniprotkb:A1L4N4|intact:EBI-2798329|uniprotkb:Q6MZU2|uniprotkb:Q9H889|uniprotkb:Q9H9E4|uniprotkb:Q9NT37|uniprotkb:Q9UF42|uniprotkb:Q4VC08|ensembl:ENSP00000256707	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:kdis_human(display_long)|uniprotkb:KIAA1250(gene name synonym)|uniprotkb:KIDINS220(gene name)|psi-mi:KIDINS220(display_short)|uniprotkb:ARMS(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_065789.1|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000134313(gene)|ensembl:ENST00000256707(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9ULH0|reactome:R-HSA-170984|reactome:R-HSA-9696270|reactome:R-HSA-9696273	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:0wyaXuvXCqQTlfjuW4TAcIGmdlw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8N163	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q7LBC6	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q96SI1	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-715783|uniprotkb:Q9BVI6|uniprotkb:A8K600|ensembl:ENSP00000394390|ensembl:ENSP00000464812|ensembl:ENSP00000467612|ensembl:ENSP00000508199	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:kcd15_human(display_long)|uniprotkb:KCTD15(gene name)|psi-mi:KCTD15(display_short)|uniprotkb:Potassium channel tetramerization domain-containing protein 15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001123466.1|refseq:NP_001123467.1|refseq:NP_076981.2|ensembl:ENSG00000153885(gene)|ensembl:ENST00000430256(transcript)|ensembl:ENST00000588881(transcript)|ensembl:ENST00000589786(transcript)|ensembl:ENST00000683859(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|reactome:R-HSA-8866904|refseq:XP_011525599.1|refseq:XP_011525600.1|refseq:XP_016882772.1|refseq:XP_011525598.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:diG+43SilvYzJJ0SCB3HY+ktJMQ9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q13418	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-747644|uniprotkb:P57043|uniprotkb:Q68DZ3|uniprotkb:B7Z1I0|uniprotkb:D3DQU0|uniprotkb:B7Z418|ensembl:ENSP00000299421|ensembl:ENSP00000379975|ensembl:ENSP00000403487	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ilk_human(display_long)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:p59ILK(gene name synonym)|uniprotkb:ILK(gene name)|psi-mi:ILK(display_short)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001265370.1|refseq:NP_001014794.1|refseq:NP_001014795.1|refseq:NP_004508.1|refseq:XP_005252961.1|refseq:NP_001265371.1|refseq:XP_005252962.1|refseq:XP_011518367.1|dip:DIP-38657N|rcsb pdb:3IXE|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIB|reactome:R-HSA-446343|reactome:R-HSA-446353|ensembl:ENSG00000166333(gene)|ensembl:ENST00000299421(transcript)|ensembl:ENST00000396751(transcript)|ensembl:ENST00000420936(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|mint:Q13418|rcsb pdb:2KBX|rcsb pdb:3F6Q|go:"GO:0045663"(positive regulation of myoblast differentiation)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:FrK/MsW7IcVWT9VbkHAIVHEh1P89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q12894	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2512448|ensembl:ENSP00000402849|intact:EBI-6115935|uniprotkb:Q9BVB4|uniprotkb:Q9UJ88	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ifrd2_human(display_long)|uniprotkb:Protein SKMC15(gene name synonym)|uniprotkb:IFRD2(gene name)|psi-mi:IFRD2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000214706(gene)|ensembl:ENST00000417626(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR006921(Interferon-related protein conserved region)|interpro:IPR007701(Interferon-related developmental regulator)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039777|refseq:NP_006755.4	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:ktxpbUgNcw2DWOJw8o1R4s+U3a09606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q16665	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-447269|uniprotkb:Q53XP6|uniprotkb:Q96PT9|uniprotkb:Q9UPB1|uniprotkb:C0LZJ3|ensembl:ENSP00000338018	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:hif1a_human(display_long)|uniprotkb:ARNT-interacting protein(gene name synonym)|uniprotkb:Member of PAS protein 1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)|uniprotkb:HIF1A(gene name)|psi-mi:HIF1A(display_short)|uniprotkb:MOP1(gene name synonym)|uniprotkb:BHLHE78(gene name synonym)|uniprotkb:PASD8(gene name synonym)|uniprotkb:PAS domain-containing protein 8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001230013.1|refseq:NP_001521.1|refseq:NP_851397.1|ensembl:ENST00000323441|ensembl:ENSP00000323326|ensembl:ENSP00000338018|ensembl:ENST00000539097|ensembl:ENSP00000437955|dip:DIP-29722N|ensembl:ENSG00000100644(gene)|ensembl:ENST00000337138(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q16665|rcsb pdb:1D7G|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1L3E|rcsb pdb:1L8C|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:2ILM|rcsb pdb:3HQR|rcsb pdb:3HQU|rcsb pdb:4AJY|rcsb pdb:4H6J|rcsb pdb:5JWP|rcsb pdb:5L9B|rcsb pdb:5L9V|rcsb pdb:5LA9|rcsb pdb:5LAS|rcsb pdb:6GFX|rcsb pdb:6GMR|rcsb pdb:6YW3|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|reactome:R-HSA-2122947|reactome:R-HSA-400253|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8849473|reactome:R-HSA-8857538|reactome:R-HSA-8951664	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:3XRt8HFMCRlxcYR2KfuFSq6gVBg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9ULT8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-310559|uniprotkb:Q6P445|uniprotkb:Q86VJ1|uniprotkb:Q96F34|uniprotkb:Q9UFZ7|uniprotkb:D3DS86|ensembl:ENSP00000382269|ensembl:ENSP00000450697	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:hecd1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)|uniprotkb:KIAA1131(gene name synonym)|uniprotkb:HECT domain-containing protein 1(gene name synonym)|uniprotkb:E3 ligase for inhibin receptor(gene name synonym)|uniprotkb:EULIR(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000092148(gene)|ensembl:ENST00000399332(transcript)|ensembl:ENST00000553700(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200|mint:Q9ULT8|rcsb pdb:2DK3|rcsb pdb:3DKM|reactome:R-HSA-983168|rcsb pdb:2LC3|refseq:XP_005267559.2|ensembl:ENSP00000382269|ensembl:ENSP00000450697|refseq:NP_056197.3|dip:DIP-31669N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:/l60ZSm+P4Vlc8B79wS7+T1Zvzk9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q00341	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|intact:EBI-28974616|ensembl:ENSP00000399139	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSP00000399139|refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_016859429.1|ensembl:ENSG00000115677(gene)|ensembl:ENST00000427183(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0045296"(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_005247060.2	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:4NqKFEjUn5Fi5Ws3tirpanGqYwg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O15379	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-607682|uniprotkb:O43268|uniprotkb:Q9UEI5|uniprotkb:Q9UEV0|uniprotkb:D3DQE1|ensembl:ENSP00000302967	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:hdac3_human(display_long)|uniprotkb:HDAC3(gene name)|psi-mi:HDAC3(display_short)|uniprotkb:RPD3-2(gene name synonym)|uniprotkb:SMAP45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_003874.2|dip:DIP-24253N|ensembl:ENSG00000171720(gene)|ensembl:ENST00000305264(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O15379|rcsb pdb:4A69|reactome:R-HSA-1368071|reactome:R-HSA-193670|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-390471|reactome:R-HSA-400206|reactome:R-HSA-5617472|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-400253	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:X5pnE98s15eXKev3nauN7ri5kqg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9Y450	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2868258|uniprotkb:Q5T7G3|uniprotkb:Q4VX90|uniprotkb:Q4VX89|uniprotkb:Q9UPW3|uniprotkb:Q8NDW9|uniprotkb:B7Z365|ensembl:ENSP00000356811	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:hbs1l_human(display_long)|uniprotkb:HBS1L(gene name)|psi-mi:HBS1L(display_short)|uniprotkb:HBS1(gene name synonym)|uniprotkb:KIAA1038(gene name synonym)|uniprotkb:ERFS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001138630.1|refseq:NP_001138679.1|refseq:NP_006611.1|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR037189|mint:Q9Y450|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|reactome:R-HSA-429958|ensembl:ENSG00000112339(gene)|ensembl:ENST00000367837(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:j93qk+f9rW1/Sem+tUzRay6UcKw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9H6D7	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2558168|uniprotkb:Q86U43|uniprotkb:Q86T16|uniprotkb:Q86T15|uniprotkb:Q9NX59|uniprotkb:B7WP17|uniprotkb:D3DS34|ensembl:ENSP00000206474|ensembl:ENSP00000441026	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:haus4_human(display_long)|uniprotkb:HAUS4(gene name)|psi-mi:HAUS4(display_short)|uniprotkb:C14orf94(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001159741.1|refseq:NP_001159742.1|refseq:NP_060285.2|dip:DIP-48837N|ensembl:ENSG00000092036(gene)|ensembl:ENST00000206474(transcript)|ensembl:ENST00000541587(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026214|interpro:IPR029327|mint:Q9H6D7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:KWVJQqpFmFVFufH4Pq2Ecvp7SUA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8IYU2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-308277|uniprotkb:A8K6U5|uniprotkb:B3KY89|uniprotkb:B4DFM6|uniprotkb:B4DTQ4|uniprotkb:B7Z9X6|uniprotkb:E9PGP0|uniprotkb:Q5VU99|uniprotkb:Q5VUA0|uniprotkb:Q8ND12|uniprotkb:Q9P2M6|ensembl:ENSP00000262903	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:hace1_human(display_long)|uniprotkb:KIAA1320(gene name synonym)|uniprotkb:HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1(gene name synonym)|uniprotkb:HACE1(gene name)|psi-mi:HACE1(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HACE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_065822.2|ensembl:ENSG00000085382(gene)|ensembl:ENST00000262903(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061025"(membrane fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|reactome:R-HSA-983168|refseq:NP_001308009.1|refseq:NP_001308012.1|refseq:NP_001308013.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:zr6DnEjPI0FB03Xsq5eHOJSIcos9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UKJ3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-948259|ensembl:ENSP00000467556|uniprotkb:B9EGP9|uniprotkb:Q8TB99|uniprotkb:O60300	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:gptc8_human(display_long)|uniprotkb:GPATCH8(gene name)|psi-mi:GPATCH8(display_short)|uniprotkb:GPATC8(gene name synonym)|uniprotkb:KIAA0553(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000186566(gene)|ensembl:ENST00000591680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|refseq:NP_001002909.1|refseq:NP_001291868.1|refseq:NP_001291869.1|refseq:NP_001291870.1|refseq:NP_001291871.1|refseq:NP_001291872.1|refseq:XP_016879864.1|refseq:XP_016879865.1|refseq:XP_016879866.1|refseq:XP_016879867.1|refseq:XP_016879868.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:moPN1LjhDaFc24jYnKyPhgWHiF89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O60547	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-746373|uniprotkb:O75357|uniprotkb:Q5T954|uniprotkb:Q6FH09|uniprotkb:Q9UGZ3|uniprotkb:Q9UJK9|ensembl:ENSP00000370194|intact:EBI-10968896|uniprotkb:E9PI88	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:gmds_human(display_long)|uniprotkb:GDP-D-mannose dehydratase(gene name synonym)|uniprotkb:GMDS(gene name)|psi-mi:GMDS(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001491.1|ensembl:ENSG00000112699(gene)|ensembl:ENST00000380815(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008446"(GDP-mannose 4,6-dehydratase activity)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0042351"('de novo' GDP-L-fucose biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070401"(NADP+ binding)|interpro:IPR006368(GDP-mannose 4,6-dehydratase)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:1T2A|rcsb pdb:5IN4|rcsb pdb:5IN5|rcsb pdb:6GPJ|rcsb pdb:6GPK|rcsb pdb:6GPL|rcsb pdb:6Q94|reactome:R-HSA-6787639|refseq:NP_001240775.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:phGw3/m75gYQcBlRP3OXK4mQvhM9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q06787	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:+iN/J/MbxTcRwgDezYseEDwLep49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NRA8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P06730	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9H9B1	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q96F86	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O75190	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9Y678	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:A5YKK6	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q99439	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2961712|ensembl:ENSP00000263097|uniprotkb:Q92578|uniprotkb:A5D8U8|uniprotkb:D6W5X9|uniprotkb:A6NFI4	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:cnn2_human(display_long)|uniprotkb:CNN2(gene name)|psi-mi:CNN2(display_short)|uniprotkb:Calponin H2, smooth muscle(gene name synonym)|uniprotkb:Neutral calponin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000064666(gene)|ensembl:ENST00000263097(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045296"(cadherin binding)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029974|interpro:IPR036872|rcsb pdb:1WYN|reactome:R-HSA-6798695|reactome:R-HSA-8950505|refseq:NP_004359.1|refseq:NP_958434.1|refseq:NP_001290428.1|refseq:NP_001290430.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:64KRSh4MEocrTZ8EuTz9ni8ahhc9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q96ST8	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2799206|uniprotkb:Q8N5J8|uniprotkb:B9EGA6|ensembl:ENSP00000306105	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:cep89_human(display_long)|uniprotkb:CCDC123(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 123(gene name synonym)|uniprotkb:CEP89(gene name)|psi-mi:CEP89(display_short)|uniprotkb:Centrosomal protein 123(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:XP_011525727.1|refseq:NP_116205.3|ensembl:ENSG00000121289(gene)|ensembl:ENST00000305768(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0031514"(motile cilium)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR033545|mint:Q96ST8|reactome:R-HSA-5620912|go:"GO:0045202"(synapse)|dip:DIP-47325N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:u/Ov7ZA+Q741uaCU5woCf7Iz3zE9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q5VT06	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-947346|uniprotkb:O75068|uniprotkb:Q8TDK3|uniprotkb:Q8WY20|ensembl:ENSP00000356579	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ce350_human(display_long)|uniprotkb:CEP350(gene name)|psi-mi:CEP350(display_short)|uniprotkb:CAP350(gene name synonym)|uniprotkb:GM133(orf name)|uniprotkb:KIAA0480(gene name synonym)|uniprotkb:Centrosome-associated protein of 350 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_055625.4|dip:DIP-49946N|ensembl:ENSG00000135837(gene)|ensembl:ENST00000367607(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042995"(cell projection)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR025486|interpro:IPR028750|interpro:IPR036859|rcsb pdb:2COZ	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:lwAOfFoQPaS6NHQ1NkmFWBfVA3s9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q12834	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-367462|uniprotkb:Q5JUY4|uniprotkb:Q9BW56|uniprotkb:Q9UQI9|uniprotkb:B2R6Z6|uniprotkb:D3DPJ1|ensembl:ENSP00000308450|ensembl:ENSP00000361540	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:cdc20_human(display_long)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:p55CDC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	rcsb pdb:6Q6H|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174048|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176417|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-5689880|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983168|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q12834|rcsb pdb:4GGA|rcsb pdb:4GGC|rcsb pdb:4GGD|rcsb pdb:4N14|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6Q6G|refseq:NP_001246.2|ensembl:ENSG00000117399(gene)|ensembl:ENST00000310955(transcript)|ensembl:ENST00000372462(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-29655N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:15j9Heovw6LpbClp5kT9Wz6a88A9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8WXE0	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2622376|uniprotkb:B4DTT3|uniprotkb:Q9ULT1|intact:EBI-3446386|uniprotkb:B7Z9H1|uniprotkb:Q7LG69|ensembl:ENSP00000325355	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:cski2_human(display_long)|uniprotkb:CASK-interacting protein 2(gene name synonym)|uniprotkb:CASKIN2(gene name)|psi-mi:CASKIN2(display_short)|uniprotkb:KIAA1139(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001136115.1|refseq:NP_065804.2|ensembl:ENSP00000325355|ensembl:ENST00000433559|ensembl:ENSP00000406963|ensembl:ENSG00000177303(gene)|ensembl:ENST00000321617(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR027013|interpro:IPR032117|interpro:IPR032232|interpro:IPR035497|interpro:IPR035498|interpro:IPR035499|interpro:IPR036028|interpro:IPR036770|rcsb pdb:2KE9|rcsb pdb:4IS7|rcsb pdb:5L1M	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:XLOkvhXMcYWuzRMNrR3q+K4PoCg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9UKZ1	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9BY42	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1045669|uniprotkb:Q9BYL7|uniprotkb:Q9HCV9|uniprotkb:Q9NX29|uniprotkb:Q9NZZ8|uniprotkb:Q9P002|uniprotkb:Q9UHW3|uniprotkb:E1P5Z9|ensembl:ENSP00000349906	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:rtf2_human(display_long)|uniprotkb:RTF2(gene name)|psi-mi:RTF2(display_short)|uniprotkb:C20orf43(gene name synonym)|uniprotkb:RTFDC1(gene name synonym)|uniprotkb:Replication termination factor 2 domain-containing protein 1(gene name synonym)|uniprotkb:AD-007(orf name)|uniprotkb:CDA05(orf name)|uniprotkb:HSPC164(orf name)|uniprotkb:HSPC169(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001269964.1|refseq:NP_001269965.1|refseq:NP_001269966.1|refseq:NP_057491.2|ensembl:ENSG00000022277(gene)|go:"GO:0003677"(DNA binding)|ensembl:ENST00000357348(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0071171"(site-specific DNA replication termination at RTS1 barrier)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1902979"(mitotic DNA replication termination)|interpro:IPR006735(Protein of unknown function DUF602)|interpro:IPR027799	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:eh/6sc/MIM9QOLgd0NfZaezJ7ek9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q6ZUT1	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3920396|ensembl:ENSP00000339076|ensembl:ENSP00000402208|uniprotkb:Q7Z357|uniprotkb:Q8N2T3|uniprotkb:Q6IN53|uniprotkb:Q5RL41	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:nkap1_human(display_long)|uniprotkb:NKAPD1(gene name)|psi-mi:NKAPD1(display_short)|uniprotkb:C11orf57(gene name synonym)|uniprotkb:NKAP domain containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000150776(gene)|ensembl:ENST00000280352(transcript)|ensembl:ENST00000420986(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR043407|refseq:NP_001287946.1|refseq:NP_001287948.1|refseq:NP_001287950.1|refseq:NP_001076439.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:7Lz1Il3OjnAW5tcASdyVUZf+4y89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P20290	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741(gene)|ensembl:ENST00000380591(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9NVI7	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:IZKJEVLLS/DFINgBgO5frizN1P49606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8NBU5	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2511886|ensembl:ENSP00000339016|ensembl:ENSP00000339017|ensembl:ENSP00000489353|ensembl:ENSP00000489455|ensembl:ENSP00000506333|uniprotkb:Q6P4B9|uniprotkb:Q969Y3|uniprotkb:Q8WYR9|uniprotkb:Q8N3G1|uniprotkb:Q6DKG1|uniprotkb:D3DR26	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:atad1_human(display_long)|uniprotkb:ATAD1(gene name)|psi-mi:ATAD1(display_short)|uniprotkb:Thorase(gene name synonym)|uniprotkb:FNP001(orf name)|uniprotkb:ATPase family AAA domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000138138(gene)|ensembl:ENSG00000283024(gene)|ensembl:ENST00000308448(transcript)|ensembl:ENST00000328142(transcript)|ensembl:ENST00000634773(transcript)|ensembl:ENST00000634970(transcript)|ensembl:ENST00000680024(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|reactome:R-HSA-9603798|refseq:NP_116199.2|refseq:NP_001308896.1|refseq:XP_005270309.1|refseq:XP_016872336.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:IGkIH4udjuFoshP9hMDDK0ARNOg9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9H765	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-3942509|uniprotkb:Q547Q2|uniprotkb:A8K1P2|ensembl:ENSP00000320893|ensembl:ENSP00000445622	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:asb8_human(display_long)|uniprotkb:ASB8(gene name)|psi-mi:ASB8(display_short)|uniprotkb:PP14212(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000177981(gene)|ensembl:ENST00000317697(transcript)|ensembl:ENST00000536549(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037332|mint:Q9H765|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_077000.1|refseq:NP_001306225.1|refseq:NP_001306226.1|refseq:NP_001306227.1|refseq:NP_001306228.1|refseq:NP_001306229.1|refseq:NP_001306230.1	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:TLjOfkyUnX91j0Lh2kZvf2uBMGI9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8WXK3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-707573|uniprotkb:D3DRR2|uniprotkb:Q96EP7|uniprotkb:Q9H8Z1|uniprotkb:A8K7Q6|ensembl:ENSP00000350331	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:asb13_human(display_long)|uniprotkb:ASB13(gene name)|psi-mi:ASB13(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_078977.2|ensembl:ENSG00000196372(gene)|ensembl:ENST00000357700(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037334|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:KvLeTaTDP6bkB0jmqmDp1qd5L+E9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:P27540	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-80809|uniprotkb:C4AMA1|ensembl:ENSP00000351407|uniprotkb:B2R9H1|uniprotkb:F8WAP6|uniprotkb:Q59ED4|uniprotkb:Q5QP39|uniprotkb:Q8NDC7	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:arnt_human(display_long)|uniprotkb:ARNT(gene name)|psi-mi:ARNT(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym)|uniprotkb:BHLHE2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000143437(gene)|ensembl:ENST00000358595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|refseq:NP_001184254.1|refseq:NP_001659.1|refseq:NP_848514.1|refseq:NP_001272964.1|refseq:NP_001272965.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:P27540|rcsb pdb:1D7G|rcsb pdb:1X0O|rcsb pdb:2A24|rcsb pdb:2ARN|rcsb pdb:2B02|rcsb pdb:2HV1|rcsb pdb:2K7S|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6X21|rcsb pdb:3H82|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:4EQ1|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4H6J|rcsb pdb:4LPZ|rcsb pdb:4PKY|rcsb pdb:4XT2|reactome:R-HSA-1234158|rcsb pdb:5TBM|reactome:R-HSA-1989781|reactome:R-HSA-211945|rcsb pdb:5UFP|reactome:R-HSA-211976|reactome:R-HSA-211981|rcsb pdb:5V0L|rcsb pdb:6CZW|reactome:R-HSA-8937144|ensembl:ENST00000354396|ensembl:ENSP00000346372|ensembl:ENSP00000351407|ensembl:ENST00000505755|ensembl:ENSP00000427571|ensembl:ENST00000515192|ensembl:ENSP00000423851|refseq:XP_016856778.1|dip:DIP-30886N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:MAYVa32fLDGxgEr0VL9ZVg/EcIA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q92625	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1048612|uniprotkb:Q5JYI9|uniprotkb:Q5SYR2|uniprotkb:Q86WQ7|uniprotkb:A2RUC1|ensembl:ENSP00000353518|uniprotkb:B4DQW8	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ans1a_human(display_long)|uniprotkb:Odin(gene name synonym)|uniprotkb:ANKS1A(gene name)|psi-mi:ANKS1A(display_short)|uniprotkb:ANKS1(gene name synonym)|uniprotkb:KIAA0229(gene name synonym)|uniprotkb:ODIN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_056060.2|ensembl:ENSG00000064999(gene)|ensembl:ENST00000360359(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0016322"(neuron remodeling)|go:"GO:0043005"(neuron projection)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:1901187"(regulation of ephrin receptor signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR033637|interpro:IPR036770|interpro:IPR041880|interpro:IPR041882|mint:Q92625|rcsb pdb:2LMR|rcsb pdb:2MYQ|rcsb pdb:6F7O	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:VTw7RU5nIxHSxvQdBUT/YFlQzU89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9ULJ7	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-5653671|uniprotkb:Q6N064|uniprotkb:A8K4V3|uniprotkb:Q6ZSE6|uniprotkb:B4DHJ6|uniprotkb:E9PDW0|ensembl:ENSP00000425658	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anr50_human(display_long)|uniprotkb:KIAA1223(gene name synonym)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	dip:DIP-47302N|refseq:NP_001161354.1|refseq:NP_065070.1|refseq:XP_016863960.1|ensembl:ENSG00000151458(gene)|ensembl:ENST00000504087(transcript)|go:"GO:0005768"(endosome)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9ULJ7	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:cP1xkkSlKwersPLj/gvrnWOjm+89606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8N8A2	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001182073.1|refseq:NP_710181.2|refseq:XP_005247005.1|ensembl:ENSG00000065413(gene)|ensembl:ENST00000282272(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8N8A2	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O15084	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q96NW4	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-6125599|uniprotkb:Q71MF5|uniprotkb:Q86UC3|uniprotkb:Q8ND80|uniprotkb:Q9H0I4|ensembl:ENSP00000304292	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anr27_human(display_long)|uniprotkb:ANKRD27(gene name)|psi-mi:ANKRD27(display_short)|uniprotkb:VPS9 domain-containing protein(gene name synonym)|uniprotkb:PP12899(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_115515.2|refseq:XP_006723475.1|dip:DIP-57614N|ensembl:ENSG00000105186(gene)|ensembl:ENST00000306065(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0097422"(tubular endosome)|interpro:IPR002110(Ankyrin)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037191|mint:Q96NW4|rcsb pdb:4B93|rcsb pdb:4CYM|rcsb pdb:4CZ2|rcsb pdb:6TL0|reactome:R-HSA-8876198	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:1hfY0RGhjr0U+gpqsM9HLYLs3Ks9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:O75179	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-355530|uniprotkb:Q6PJ85|uniprotkb:Q6PK85|uniprotkb:Q6PKA2|uniprotkb:Q86XI3|uniprotkb:Q8NDR5|uniprotkb:Q96I86|uniprotkb:Q9H6J9|uniprotkb:Q9H288|ensembl:ENSP00000351416|uniprotkb:G5E964|uniprotkb:E7EUV3	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anr17_human(display_long)|uniprotkb:ANKRD17(gene name)|psi-mi:ANKRD17(display_short)|uniprotkb:GTAR(gene name synonym)|uniprotkb:KIAA0697(gene name synonym)|uniprotkb:Gene trap ankyrin repeat protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_115593.3|refseq:NP_942592.1|refseq:NP_056389.1|ensembl:ENSG00000132466(gene)|ensembl:ENST00000358602(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900245"(positive regulation of MDA-5 signaling pathway)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR002110(Ankyrin)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR020683|interpro:IPR036612|interpro:IPR036770|mint:O75179|go:"GO:0031965"(nuclear membrane)|refseq:NP_001273700.1|ensembl:ENST00000330838|ensembl:ENSP00000332265|ensembl:ENSP00000351416|ensembl:ENST00000509867|ensembl:ENSP00000427151|dip:DIP-47290N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:l/gkMCasWF6pn6feuIzeQKWwwKM9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q8IWZ3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-359558|ensembl:ENSP00000354085|intact:EBI-948598|uniprotkb:A6NH85|uniprotkb:Q149P2|uniprotkb:Q8IWZ2|uniprotkb:Q8WY90|uniprotkb:Q96G77|uniprotkb:Q96GK0|uniprotkb:Q9H2U0|uniprotkb:Q9HA95|uniprotkb:Q9NWG4|uniprotkb:Q9UPR7	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:ankh1_human(display_long)|uniprotkb:Multiple ankyrin repeats single KH domain(gene name synonym)|uniprotkb:ANKHD1(gene name)|psi-mi:ANKHD1(display_short)|uniprotkb:HIV-1 Vpr-binding ankyrin repeat protein(gene name synonym)|uniprotkb:KIAA1085(gene name synonym)|uniprotkb:MASK(gene name synonym)|uniprotkb:VBARP(gene name synonym)|uniprotkb:PP2500(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	ensembl:ENSG00000131503(gene)|ensembl:ENST00000360839(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045087"(innate immune response)|interpro:IPR002110(Ankyrin)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR020683|interpro:IPR036612|interpro:IPR036770|refseq:NP_001183959.1|refseq:NP_060217.1|refseq:NP_060448.1|refseq:NP_078944.2|refseq:NP_065741.3|ensembl:ENSP00000354085|ensembl:ENST00000394722|ensembl:ENSP00000378211|ensembl:ENST00000394723|ensembl:ENSP00000378212|ensembl:ENST00000616482|ensembl:ENSP00000478529|dip:DIP-36371N	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:yPjTR77ttPwAEMg8WHOzYJNcAhA9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NWT6	uniprotkb:Q9P2R3	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502476|imex:IM-22750-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405	-	-	-	figure legend:Table S1|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: NACA (UniProtKB accessions: E9PAV3;Q13765); TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2020/06/18	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rogid:237ungtRc80jqTOKBUnFX9qDUGw9606	rigid:/E4TJ1NAxCm9Gu3eRm5mwZgg0O8	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q7Z6Z7	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q92878	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8N726	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q14574	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-6163585|intact:EBI-28985956|uniprotkb:A6NN35|uniprotkb:Q14200|uniprotkb:Q9HAZ9|ensembl:ENSP00000353608	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dsc3_human(display_long)|uniprotkb:Cadherin family member 3(gene name synonym)|uniprotkb:DSC4(gene name synonym)|uniprotkb:Desmocollin-4(gene name synonym)|uniprotkb:HT-CP(gene name synonym)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:CDHF3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001932.2|refseq:NP_077741.2|ensembl:ENSP00000392068|ensembl:ENST00000434452|ensembl:ENSP00000353608|ensembl:ENSG00000134762(gene)|ensembl:ENST00000360428(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q14574|reactome:R-HSA-6805567|reactome:R-HSA-6809371|interpro:IPR002126(Cadherin)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:2En63we0WgDfQQY2f4qQHK/clSI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q6NSI4	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-8634209|ensembl:ENSP00000361628|uniprotkb:Q9H7W5|uniprotkb:Q6PHY5|uniprotkb:Q6PII9|intact:MINT-8162145|uniprotkb:Q9NWA6|uniprotkb:Q5JQS1|uniprotkb:Q4G0L7|uniprotkb:H7BY89|uniprotkb:Q5JRF9|uniprotkb:Q6PJU8	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:radx_human(display_long)|uniprotkb:RADX(gene name)|psi-mi:RADX(display_short)|uniprotkb:CXorf57(gene name synonym)|uniprotkb:RPA-related and RAD51-antagonist, X-chromosome(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000147231(gene)|ensembl:ENST00000372548(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005657"(replication fork)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040893|refseq:NP_060485.4|refseq:NP_001171711.1	-	-	comment:mint	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:pUlTaH5Wq19LDuJp7qGlWFpa0q09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9P253	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000104142(gene)|ensembl:ENST00000220509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|refseq:NP_065908.1|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P08670	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q99536	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2514883|ensembl:ENSP00000347872|uniprotkb:Q5BKZ7|uniprotkb:A8K345|uniprotkb:Q13035|uniprotkb:Q9BUT8|uniprotkb:Q96A39|uniprotkb:B0AZP7|uniprotkb:B4DPX4	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vat1_human(display_long)|uniprotkb:VAT1(gene name)|psi-mi:VAT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	rcsb pdb:6K9Y|rcsb pdb:6LHR|rcsb pdb:6LII|reactome:R-HSA-6798695|ensembl:ENSG00000108828(gene)|ensembl:ENST00000355653(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q99536|refseq:NP_006364.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:CaICWyJ+h3ry4itndQodektQFQo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P55327	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q15388	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-711636|uniprotkb:A8K195|uniprotkb:Q498B3|uniprotkb:Q6IBT4|ensembl:ENSP00000355566	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tom20_human(display_long)|uniprotkb:Outer mitochondrial membrane receptor Tom20(gene name synonym)|uniprotkb:TOMM20(gene name)|psi-mi:TOMM20(display_short)|uniprotkb:KIAA0016(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055580.1|dip:DIP-46735N|ensembl:ENSG00000173726(gene)|ensembl:ENST00000366607(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR022422|interpro:IPR023392|rcsb pdb:4APO|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:+wNh1qTU0NtgQekYJjhfj6O3UoA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P55061	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1045825|uniprotkb:O14938|uniprotkb:Q643A7|uniprotkb:Q96J50|uniprotkb:F8W034|uniprotkb:B2R5M4|ensembl:ENSP00000267115|ensembl:ENSP00000378454|ensembl:ENSP00000448036|ensembl:ENSP00000450158	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:bi1_human(display_long)|uniprotkb:Testis-enhanced gene transcript protein(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 6(gene name synonym)|uniprotkb:TMBIM6(gene name)|psi-mi:TMBIM6(display_short)|uniprotkb:BI1(gene name synonym)|uniprotkb:TEGT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001092046.1|refseq:NP_003208.2|ensembl:ENSG00000139644(gene)|ensembl:ENST00000267115(transcript)|ensembl:ENST00000395006(transcript)|ensembl:ENST00000549385(transcript)|ensembl:ENST00000552370(transcript)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR006213(Bax inhibitor 1, conserved site)|interpro:IPR006214(Protein of unknown function UPF0005)|mint:P55061|refseq:XP_005269183.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:l3wlIZarKWk471gkb6A5Jy/gN/U9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q99805	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567|ensembl:ENSP00000493515	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004791.1|ensembl:ENSG00000125304(gene)|ensembl:ENST00000376387(transcript)|ensembl:ENST00000642475(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q99805	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q96A49	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-10770179|uniprotkb:Q68CP1|uniprotkb:Q96C60|uniprotkb:Q96JQ6|uniprotkb:Q96T20|ensembl:ENSP00000369500	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:syap1_human(display_long)|uniprotkb:SYAP1(gene name)|psi-mi:SYAP1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)|uniprotkb:PRO3113(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_116185.2|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|rcsb pdb:1X3A|ensembl:ENSG00000169895(gene)|ensembl:ENST00000380155(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:+gHfLl7YaR8geuci2/cAYP8CiKA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P61956	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:WgudlZhwtQbQInv29BniecTYGY89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y2Z0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8N0X7	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2643803|uniprotkb:Q9H1T3|uniprotkb:Q9H1T2|uniprotkb:O60349|uniprotkb:Q86Y67|ensembl:ENSP00000347314|ensembl:ENSP00000406061|ensembl:ENSP00000414147|ensembl:ENSP00000473599|ensembl:ENSP00000497209	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:spart_human(display_long)|uniprotkb:SPART(gene name)|psi-mi:SPART(display_short)|uniprotkb:KIAA0610(gene name synonym)|uniprotkb:SPG20(gene name synonym)|uniprotkb:Spastic paraplegia 20 protein(gene name synonym)|uniprotkb:TAHCCP1(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001135766.1|refseq:NP_001135767.1|refseq:NP_001135768.1|refseq:NP_055902.1|refseq:XP_011533314.1|refseq:XP_005266370.1|refseq:XP_005266371.1|refseq:XP_005266372.1|ensembl:ENSG00000133104(gene)|ensembl:ENST00000355182(transcript)|ensembl:ENST00000438666(transcript)|ensembl:ENST00000451493(transcript)|ensembl:ENST00000494062(transcript)|ensembl:ENST00000650221(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009838"(abscission)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0048698"(negative regulation of collateral sprouting in absence of injury)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051301"(cell division)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|interpro:IPR007330(MIT)|interpro:IPR009686(Senescence-associated)|interpro:IPR036181|rcsb pdb:2DL1|rcsb pdb:4U7I|go:"GO:0030514"(negative regulation of BMP signaling pathway)|refseq:XP_005266374.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Km2bYRg7JLYy7voEgYVdAHZhzE09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P30825	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-4289564|uniprotkb:Q5JR50|ensembl:ENSP00000370128	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sl7a1_human(display_long)|uniprotkb:SLC7A1(gene name)|psi-mi:SLC7A1(display_short)|uniprotkb:ATRC1(gene name synonym)|uniprotkb:ERR(gene name synonym)|uniprotkb:REC1L(gene name synonym)|uniprotkb:Ecotropic retroviral leukemia receptor homolog(gene name synonym)|uniprotkb:Ecotropic retrovirus receptor homolog(gene name synonym)|uniprotkb:Solute carrier family 7 member 1(gene name synonym)|uniprotkb:System Y+ basic amino acid transporter(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003036.1|ensembl:ENSG00000139514(gene)|ensembl:ENST00000380752(transcript)|go:"GO:0000064"(L-ornithine transmembrane transporter activity)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015181"|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015807"(L-amino acid transport)|go:"GO:0015819"(lysine transport)|go:"GO:0015822"(ornithine transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0097638"(L-arginine import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903352"(L-ornithine transmembrane transport)|go:"GO:1903810"(L-histidine import across plasma membrane)|go:"GO:1903826"(L-arginine transmembrane transport)|go:"GO:1990822"(basic amino acid transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|reactome:R-HSA-352230|refseq:XP_005266564.1|refseq:XP_016876205.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:0Y2qLKGZJkRCQmCro2MEGj6tEr49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O43765	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9H9B4	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355861|uniprotkb:Q9HA53|uniprotkb:B3KPW3|uniprotkb:D3DQN2|ensembl:ENSP00000316905	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sfxn1_human(display_long)|uniprotkb:SFXN1(gene name)|psi-mi:SFXN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_073591.2|refseq:NP_001309906.1|ensembl:ENSG00000164466(gene)|ensembl:ENST00000321442(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9H9B4	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:n/i6d8Rt+xMOvu3BrZfc0VP0+Wk9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O76021	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P62979	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q5UIP0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UL46	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-741630|uniprotkb:Q15129|ensembl:ENSP00000216802|ensembl:ENSP00000495790	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psme2_human(display_long)|uniprotkb:Proteasome activator 28 subunit beta(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 2(gene name synonym)|uniprotkb:11S regulator complex subunit beta(gene name synonym)|uniprotkb:PSME2(gene name)|psi-mi:PSME2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002809.2|ensembl:ENSG00000100911(gene)|ensembl:ENSG00000284889(gene)|ensembl:ENST00000216802(transcript)|ensembl:ENST00000645325(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q9UL46|rcsb pdb:7DR6|rcsb pdb:7DRW|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-5678895|reactome:R-HSA-174178|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8950505|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:I1OweiKOkWYntSzrxcNfWjAHgx49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O00232	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P28070	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95602	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359472|uniprotkb:Q9UEH0|uniprotkb:Q9UFT9|uniprotkb:Q0VG05|uniprotkb:B7Z7T0|uniprotkb:D6W5M0|ensembl:ENSP00000263857	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rpa1_human(display_long)|uniprotkb:POLR1A(gene name)|psi-mi:POLR1A(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:A190(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_056240.2|ensembl:ENST00000263857(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|mint:O95602|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|ensembl:ENSG00000068654(gene)|dip:DIP-27537N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:EDNwLyujEW01bH48PD19pr3/lgU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q96JN8	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1053406|uniprotkb:Q6GPI8|uniprotkb:Q96IU9|uniprotkb:Q9H0B0|intact:EBI-2563327|intact:EBI-28979128|ensembl:ENSP00000382390|ensembl:ENSP00000500916	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:neul4_human(display_long)|uniprotkb:NEURL4(gene name)|psi-mi:NEURL4(display_short)|uniprotkb:KIAA1787(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001005408.1|refseq:NP_115818.2|ensembl:ENST00000315614|ensembl:ENSP00000319826|ensembl:ENSP00000382390|ensembl:ENSP00000500916|ensembl:ENST00000673081|ensembl:ENSP00000500667|ensembl:ENSG00000215041(gene)|ensembl:ENSG00000288301(gene)|ensembl:ENST00000399464(transcript)|ensembl:ENST00000671847(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006573(NEUZ)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037962|interpro:IPR043136|mint:Q96JN8|rcsb pdb:2E63	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:lydZRBsnJDyAdaDjTe7gJVkxL149606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8N6R0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1053295|uniprotkb:A6NFK0|uniprotkb:Q53EZ6|uniprotkb:O94940|uniprotkb:Q5TGP9|uniprotkb:Q5TGQ0|uniprotkb:Q8N2P8|uniprotkb:Q96J11|uniprotkb:Q96SQ0|uniprotkb:Q9Y2Z1|uniprotkb:Q9Y3M6|uniprotkb:A8K6S5|intact:EBI-1059000|ensembl:ENSP00000354920	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:efnmt_human(display_long)|uniprotkb:METTL13(gene name)|psi-mi:METTL13(display_short)|uniprotkb:EEF1AKNMT(gene name synonym)|uniprotkb:FEAT(gene name synonym)|uniprotkb:KIAA0859(gene name synonym)|uniprotkb:Methyltransferase-like protein 13(gene name synonym)|uniprotkb:CGI-01(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001007240.1|refseq:NP_055770.1|refseq:NP_057019.3|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q8N6R0|rcsb pdb:5WCJ|ensembl:ENSG00000010165(gene)|ensembl:ENST00000361735(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:BAuWTz48t+/xwoky1nsCnGWtp/c9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8IW41	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1201460|uniprotkb:O60491|uniprotkb:Q86X46|uniprotkb:Q9BVX9|uniprotkb:Q9UG86|uniprotkb:B3KVA5|ensembl:ENSP00000449381	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mapk5_human(display_long)|uniprotkb:MAPKAPK5(gene name)|psi-mi:MAPKAPK5(display_short)|uniprotkb:PRAK(gene name synonym)|uniprotkb:p38-regulated/activated protein kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003659.2|refseq:NP_620777.1|ensembl:ENSG00000089022(gene)|ensembl:ENST00000551404(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090398"(cellular senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR027442|reactome:R-HSA-2559580|reactome:R-HSA-5687128|reactome:R-HSA-6804756	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:1zo/tqh0/AXCMb9uERCgKWX7RoI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y4Y9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-373007|ensembl:ENSP00000410758	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q86WA8	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2513996|ensembl:ENSP00000285737|uniprotkb:Q96K43|uniprotkb:Q8N3B9|uniprotkb:Q0D2H6|uniprotkb:Q8NCE9|uniprotkb:B7ZKL7	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:lonp2_human(display_long)|uniprotkb:LONP2(gene name)|psi-mi:LONP2(display_short)|uniprotkb:LONP(gene name synonym)|uniprotkb:Lon protease-like protein 2(gene name synonym)|uniprotkb:Peroxisomal Lon protease(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000102910(gene)|ensembl:ENST00000285737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008233"(peptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0019899"(enzyme binding)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027501|reactome:R-HSA-390471|reactome:R-HSA-9033241|refseq:NP_001287877.1|refseq:NP_113678.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:WyZglDz2aZOpnRVtWTrAf62G0pA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P36776	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357448|ensembl:ENSP00000353826|intact:EBI-1054513|uniprotkb:D6W635|uniprotkb:E5KMH8|uniprotkb:P36777|uniprotkb:Q8N8K8|uniprotkb:Q9UQ95|uniprotkb:B3KPH8|uniprotkb:F5GZ27|intact:EBI-10964236	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:lonm_human(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001263408.1|go:"GO:0070407"(oxidation-dependent protein catabolic process)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027503|mint:P36776|rcsb pdb:2X36|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070182"(DNA polymerase binding)|rcsb pdb:6WYS|rcsb pdb:6WZV|rcsb pdb:6X1M|rcsb pdb:6X27|rcsb pdb:7KRZ|rcsb pdb:7KSL|rcsb pdb:7KSM|rcsb pdb:7NFY|rcsb pdb:7NG4|rcsb pdb:7NG5|rcsb pdb:7NGC|rcsb pdb:7NGF|rcsb pdb:7NGL|rcsb pdb:7NGP|rcsb pdb:7NGQ|ensembl:ENSG00000196365(gene)|ensembl:ENST00000360614(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0009725"(response to hormone)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|refseq:NP_001263409.1|refseq:NP_004784.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:quAPz1dZK2XdoE6WMjQJwFtx53o9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95202	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1052895|uniprotkb:Q9UF65|uniprotkb:B4DED2|ensembl:ENSP00000305653	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:letm1_human(display_long)|uniprotkb:Leucine zipper-EF-hand-containing transmembrane protein 1(gene name synonym)|uniprotkb:LETM1(gene name)|psi-mi:LETM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_036450.1|ensembl:ENSG00000168924(gene)|ensembl:ENST00000302787(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0015369"("calcium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042407"(cristae formation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1900069"(regulation of cellular hyperosmotic salinity response)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011685(LETM1-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR033122|interpro:IPR044202|reactome:R-HSA-8949215|reactome:R-HSA-9013408	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:mDxqXWqmgCjbaZLz4JqteqjDCik9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P08779	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356410|uniprotkb:P30654|uniprotkb:Q16402|uniprotkb:Q9UBG8|uniprotkb:A8K488|ensembl:ENSP00000301653	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:k1c16_human(display_long)|uniprotkb:KRT16(gene name)|psi-mi:KRT16(display_short)|uniprotkb:KRT16A(gene name synonym)|uniprotkb:Keratin-16(gene name synonym)|uniprotkb:Cytokeratin-16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005548.2|ensembl:ENSG00000186832(gene)|ensembl:ENST00000301653(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007568"(aging)|go:"GO:0030216"(keratinocyte differentiation)|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031424"(keratinization)|go:"GO:0042633"(hair cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08779	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:NkPTLkWquNNlGYbrXaRkyRmKvmM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q96P70	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95373	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q12905	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P05204	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228|ensembl:ENSP00000481160	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005508.1|ensembl:ENSG00000198830(gene)|ensembl:ENST00000361427(transcript)|ensembl:ENST00000619352(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95714	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1058922|uniprotkb:Q86SV7|uniprotkb:Q86SV8|uniprotkb:Q86SV9|uniprotkb:Q86YY3|uniprotkb:Q86YY4|uniprotkb:Q86YY5|uniprotkb:Q86YY6|uniprotkb:Q86YY7|uniprotkb:Q86YY8|uniprotkb:Q86YY9|uniprotkb:Q86YZ0|uniprotkb:Q86YZ1|intact:EBI-1104961|intact:EBI-28977852|ensembl:ENSP00000261609	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:herc2_human(display_long)|uniprotkb:HERC2(gene name)|psi-mi:HERC2(display_short)|uniprotkb:HECT domain and RCC1-like domain-containing protein 2(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HERC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSP00000261609|refseq:NP_004658.3|ensembl:ENSG00000128731(gene)|ensembl:ENST00000261609(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032183"(SUMO binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR000569(HECT)|interpro:IPR001199(Cytochrome b5)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR006624(Beta-propeller repeat TECPR)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR010606(Mib-herc2)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR021097|interpro:IPR035983|interpro:IPR036400|interpro:IPR037252|interpro:IPR037976|interpro:IPR041987|interpro:IPR043145|mint:O95714|rcsb pdb:2KEO|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:3KCI|rcsb pdb:4L1M|rcsb pdb:6WW4|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-983168|rcsb pdb:6WW3|dip:DIP-37632N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ejMTmb0F9pM7zfHbRscV1rIRgSw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P15104	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-746653|uniprotkb:Q499Y9|uniprotkb:Q5T9Z1|uniprotkb:Q7Z3W4|uniprotkb:Q8IZ17|ensembl:ENSP00000307900|ensembl:ENSP00000344958|ensembl:ENSP00000356537|ensembl:ENSP00000398320	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:glna_human(display_long)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:GLUL(gene name)|psi-mi:GLUL(display_short)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001028216.1|refseq:NP_001028228.1|refseq:NP_002056.2|rcsb pdb:2QC8|reactome:R-HSA-210455|reactome:R-HSA-8964539|rcsb pdb:2OJW|ensembl:ENSG00000135821(gene)|ensembl:ENST00000311223(transcript)|ensembl:ENST00000331872(transcript)|ensembl:ENST00000339526(transcript)|ensembl:ENST00000417584(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P15104|go:"GO:0006538"(glutamate catabolic process)|refseq:XP_006711341.1|dip:DIP-308N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:UOOgfw1g+kmpsEx64pUbW9GfmYw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9BWH2	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-714482|ensembl:ENSP00000358510|uniprotkb:Q9H2I6|uniprotkb:Q8NHX8|uniprotkb:B2R7W5|uniprotkb:D3DWY5	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:fund2_human(display_long)|uniprotkb:HCC3(orf name)|uniprotkb:PD03104(orf name)|uniprotkb:FUNDC2(gene name)|psi-mi:FUNDC2(display_short)|uniprotkb:HCBP6(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 6(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 3 protein(gene name synonym)|uniprotkb:DC44(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000165775(gene)|ensembl:ENST00000369498(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR007014(FUN14)|refseq:NP_076423.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:oAN8aj9JpmBS5+YUfdh8Keehk3E9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q5VYK3	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-521451|uniprotkb:O15074|uniprotkb:Q8WU82|ensembl:ENSP00000339889	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:XP_005251907.1|ensembl:ENSG00000136813(gene)|ensembl:ENST00000338205(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043248"(proteasome assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q13011	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-711968|ensembl:ENSP00000221418|ensembl:ENSP00000489530|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|uniprotkb:A8K745	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000104823(gene)|ensembl:ENSG00000282853(gene)|ensembl:ENST00000221418(transcript)|ensembl:ENST00000634245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016020"(membrane)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q13011|rcsb pdb:2VRE|reactome:R-HSA-9033241|refseq:NP_001389.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P23919	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-3916725|uniprotkb:Q6FGX1|uniprotkb:Q9BUX4|ensembl:ENSP00000304802|uniprotkb:B7ZW70	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:kthy_human(display_long)|uniprotkb:DTYMK(gene name)|psi-mi:DTYMK(display_short)|uniprotkb:CDC8(gene name synonym)|uniprotkb:TMPK(gene name synonym)|uniprotkb:TYMK(gene name synonym)|uniprotkb:dTMP kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001307832.1|refseq:NP_036277.2|refseq:NP_001158503.1|ensembl:ENSG00000168393(gene)|ensembl:ENST00000305784(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006227"(dUDP biosynthetic process)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046105"(thymidine biosynthetic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR018094|interpro:IPR018095|interpro:IPR027417|interpro:IPR039430|rcsb pdb:1E2D|rcsb pdb:1E2E|rcsb pdb:1E2F|rcsb pdb:1E2G|rcsb pdb:1E2Q|rcsb pdb:1E98|go:"GO:0009041"(uridylate kinase activity)|rcsb pdb:1E99|rcsb pdb:1E9A|rcsb pdb:1E9C|rcsb pdb:1E9D|rcsb pdb:1E9E|rcsb pdb:1E9F|rcsb pdb:1NMX|rcsb pdb:1NMY|rcsb pdb:1NMZ|rcsb pdb:1NN0|rcsb pdb:1NN1|rcsb pdb:1NN3|rcsb pdb:1NN5|rcsb pdb:2XX3|reactome:R-HSA-499943|rcsb pdb:1E9B	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:xSpam88llz2shPGiGFfMRSOfgvY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q14147	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-719374|uniprotkb:B4DMY8|intact:EBI-28983353|ensembl:ENSP00000331907	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dhx34_human(display_long)|uniprotkb:DEAH box protein 34(gene name synonym)|uniprotkb:DHX34(gene name)|psi-mi:DHX34(display_short)|uniprotkb:DDX34(gene name synonym)|uniprotkb:KIAA0134(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055496.2|ensembl:ENSG00000134815(gene)|ensembl:ENST00000328771(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|ensembl:ENSP00000331907|refseq:XP_011525852.1|refseq:XP_011525853.1|refseq:XP_005259500.1|refseq:XP_016883013.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:d+QV0IESfH9v35U1g/HVt5CEtD49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O76031	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q16878	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-3906970|uniprotkb:Q8TB64|uniprotkb:B2RAK4|uniprotkb:Q6FHZ8|uniprotkb:P78513|ensembl:ENSP00000250535	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cdo1_human(display_long)|uniprotkb:CDO1(gene name)|psi-mi:CDO1(display_short)|uniprotkb:Cysteine dioxygenase type I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001310494.1|refseq:NP_001310495.1|refseq:NP_001310496.1|refseq:NP_001792.2|ensembl:ENSG00000129596(gene)|ensembl:ENST00000250535(transcript)|go:"GO:0000097"(sulfur amino acid biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0006534"(cysteine metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007595"(lactation)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0017172"(cysteine dioxygenase activity)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0033762"(response to glucagon)|go:"GO:0042412"(taurine biosynthetic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045471"(response to ethanol)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|interpro:IPR010300(Cysteine dioxygenase type I)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|rcsb pdb:2IC1|rcsb pdb:6BGF|rcsb pdb:6BGM|rcsb pdb:6BPR|rcsb pdb:6BPS|rcsb pdb:6BPT|rcsb pdb:6BPU|rcsb pdb:6BPV|rcsb pdb:6BPW|rcsb pdb:6BPX|rcsb pdb:6CDH|rcsb pdb:6CDN|rcsb pdb:6E87|rcsb pdb:6N42|rcsb pdb:6N43|reactome:R-HSA-1614558	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:mvJo3tHTcnbDM/gnt20WXOz+qV89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q99741	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-374862|uniprotkb:Q8TB30|ensembl:ENSP00000209728|ensembl:ENSP00000497345	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cdc6_human(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:CDC18L(gene name synonym)|uniprotkb:CDC6-related protein(gene name synonym)|uniprotkb:"p62(cdc6)"(gene name synonym)|uniprotkb:Cdc18-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000094804(gene)|ensembl:ENST00000209728(transcript)|ensembl:ENST00000649662(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019900"(kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904385"(cellular response to angiotensin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041083|mint:Q99741|rcsb pdb:2CCH|rcsb pdb:2CCI|rcsb pdb:4I5L|rcsb pdb:4I5N|reactome:R-HSA-1362277|reactome:R-HSA-176187|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69017|reactome:R-HSA-69205|refseq:NP_001245.1|dip:DIP-28154N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:lnIJwO5IfQ8bIhP99eq483hAoTQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O60583	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2836757|uniprotkb:Q5I1Y0|uniprotkb:A8KA48|uniprotkb:Q29R66|uniprotkb:Q53SR4|uniprotkb:O60582|uniprotkb:D3DP73|uniprotkb:D3DP74|ensembl:ENSP00000264157	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ccnt2_human(display_long)|uniprotkb:CCNT2(gene name)|psi-mi:CCNT2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001232.1|refseq:NP_490595.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019085"(early viral transcription)|go:"GO:0019086"(late viral transcription)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0097322"(7SK snRNA binding)|ensembl:ENSG00000082258(gene)|ensembl:ENST00000264157(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR028862|interpro:IPR036915|interpro:IPR043198|mint:O60583|rcsb pdb:2IVX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|interpro:IPR013763(Cyclin-related)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:v1mUPCNA+Plg8UioUhIj1LL52fI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NZT1	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9H3K6	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1642537|uniprotkb:A1L454|uniprotkb:A7YDY3|ensembl:ENSP00000331127|ensembl:ENSP00000498355	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:bola2_human(display_long)|uniprotkb:BOLA2(gene name)|psi-mi:BOLA2(display_short)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2A(gene name synonym)|uniprotkb:My016(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:NP_001307508.1|refseq:XP_016855107.1|ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000330978(transcript)|ensembl:ENST00000651894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9H3K6|reactome:R-HSA-8950505	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:5TcFdmQcwx5trexmXkWp9Arn5zE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O14874	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1046765|uniprotkb:Q96IN5|uniprotkb:Q6FGL4|intact:EBI-1210327|uniprotkb:A8MY43|uniprotkb:Q96G95|ensembl:ENSP00000219794|ensembl:ENSP00000378405	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:bckd_human(display_long)|uniprotkb:Branched-chain alpha-ketoacid dehydrogenase kinase(gene name synonym)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005872.2|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009063"(cellular amino acid catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0045763"(negative regulation of cellular amino acid metabolic process)|go:"GO:0047323"("[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity")|interpro:IPR003594(ATP-binding region, ATPase-like)|refseq:NP_001116429.1|refseq:NP_001258855.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:O14874|reactome:R-HSA-70895|ensembl:ENSG00000103507(gene)|ensembl:ENST00000219794(transcript)|ensembl:ENST00000394951(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:0hiSb7/qtSPoHt/cmLnUo7Gq6OI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P51572	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-77683|ensembl:ENSP00000343458|ensembl:ENSP00000494052|ensembl:ENSP00000499882|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001132913.1|refseq:NP_005736.3|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|ensembl:ENSG00000185825(gene)|ensembl:ENST00000345046(transcript)|ensembl:ENST00000647529(transcript)|ensembl:ENST00000672675(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_001243376.1|refseq:NP_001132929.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O75787	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2512037|ensembl:ENSP00000490083|uniprotkb:B7Z9I3|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal accessory protein 2"(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal-interacting protein 2"(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000182220(gene)|ensembl:ENST00000636580(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021626"(central nervous system maturation)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048069"(eye pigmentation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q15904	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-714667|uniprotkb:Q8NBT4|uniprotkb:Q9H0C7|uniprotkb:A6ZKI4|ensembl:ENSP00000358777	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vas1_human(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:Protein XAP-3(gene name synonym)|uniprotkb:ATP6AP1(gene name)|psi-mi:ATP6AP1(display_short)|uniprotkb:ATP6IP1(gene name synonym)|uniprotkb:ATP6S1(gene name synonym)|uniprotkb:VATPS1(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001174.2|ensembl:ENSG00000071553(gene)|ensembl:ENST00000369762(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045851"(pH reduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR008388(ATPase, V1 complex, subunit S1)|mint:Q15904|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-77387|reactome:R-HSA-8980692|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:XP_011529481.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:c5zqmRYvzBfRy1BdJteDGueEjY49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O75947	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P53680	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-297662|ensembl:ENSP00000263270|uniprotkb:O75977|uniprotkb:Q6PK67|uniprotkb:B2R4Z4	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ap2s1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:AP2S1(gene name)|psi-mi:AP2S1(display_short)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:HA2 17 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:AP17(gene name synonym)|uniprotkb:CLAPS2(gene name synonym)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000042753(gene)|ensembl:ENST00000263270(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:6URI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004060.2|refseq:NP_067586.1|refseq:NP_001288005.1|refseq:NP_001288007.1|refseq:NP_001288010.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8IWZ3	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359558|ensembl:ENSP00000354085|intact:EBI-948598|uniprotkb:A6NH85|uniprotkb:Q149P2|uniprotkb:Q8IWZ2|uniprotkb:Q8WY90|uniprotkb:Q96G77|uniprotkb:Q96GK0|uniprotkb:Q9H2U0|uniprotkb:Q9HA95|uniprotkb:Q9NWG4|uniprotkb:Q9UPR7	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ankh1_human(display_long)|uniprotkb:Multiple ankyrin repeats single KH domain(gene name synonym)|uniprotkb:ANKHD1(gene name)|psi-mi:ANKHD1(display_short)|uniprotkb:HIV-1 Vpr-binding ankyrin repeat protein(gene name synonym)|uniprotkb:KIAA1085(gene name synonym)|uniprotkb:MASK(gene name synonym)|uniprotkb:VBARP(gene name synonym)|uniprotkb:PP2500(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000131503(gene)|ensembl:ENST00000360839(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0045087"(innate immune response)|interpro:IPR002110(Ankyrin)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR020683|interpro:IPR036612|interpro:IPR036770|refseq:NP_001183959.1|refseq:NP_060217.1|refseq:NP_060448.1|refseq:NP_078944.2|refseq:NP_065741.3|ensembl:ENSP00000354085|ensembl:ENST00000394722|ensembl:ENSP00000378211|ensembl:ENST00000394723|ensembl:ENSP00000378212|ensembl:ENST00000616482|ensembl:ENSP00000478529|dip:DIP-36371N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:yPjTR77ttPwAEMg8WHOzYJNcAhA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q13155	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NRG9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-3912901|uniprotkb:Q9UG19|uniprotkb:Q9NWI6|uniprotkb:Q5JB47|ensembl:ENSP00000209873	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:aaas_human(display_long)|uniprotkb:AAAS(gene name)|psi-mi:AAAS(display_short)|uniprotkb:ADRACALA(gene name synonym)|uniprotkb:Adracalin(gene name synonym)|uniprotkb:GL003(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001166937.1|refseq:NP_056480.1|ensembl:ENSG00000094914(gene)|ensembl:ENST00000209873(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007612"(learning)|go:"GO:0009566"(fertilization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-8980692|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:fdOcZ59NldwaQJ6nusjn8GAhszo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q71UM5	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P42677	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P04792	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N	-	-	crc64:1B4DC44A6F6606D5	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95757	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	intact:EBI-11820565	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	-	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	-	-	-	comment:P0DMV8,P0DMV9	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O14735	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358858|uniprotkb:Q6FGU1|uniprotkb:Q6ZN70|ensembl:ENSP00000219789|ensembl:ENSP00000454453|ensembl:ENSP00000457339|uniprotkb:B4DUV0|uniprotkb:H3BTV1	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cdipt_human(display_long)|uniprotkb:CDIPT(gene name)|psi-mi:CDIPT(display_short)|uniprotkb:PIS(gene name synonym)|uniprotkb:PIS1(gene name synonym)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001273514.1|refseq:NP_006310.1|ensembl:ENSG00000103502(gene)|ensembl:ENST00000219789(transcript)|ensembl:ENST00000569956(transcript)|ensembl:ENST00000570016(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043178"(alcohol binding)|go:"GO:0046341"(CDP-diacylglycerol metabolic process)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-HSA-1483226|dip:DIP-54492N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:SIs1nKd3UxZREA2Sxl4MxxBNYvM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P62158	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95816	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q96GD4	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q6P1M9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-10252512|uniprotkb:Q9H969|uniprotkb:D3DX99|uniprotkb:Q68DB4|uniprotkb:Q9BVZ3|uniprotkb:B3KU88|ensembl:ENSP00000246174|ensembl:ENSP00000361827|ensembl:ENSP00000473737|ensembl:ENSP00000474470|ensembl:ENSP00000474484|ensembl:ENSP00000474720	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:armx5_human(display_long)|uniprotkb:ARMCX5(gene name)|psi-mi:ARMCX5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001161950.1|refseq:NP_001161951.1|refseq:NP_001161952.1|refseq:NP_001161954.1|refseq:NP_001161957.1|refseq:NP_073749.2|ensembl:ENSG00000125962(gene)|ensembl:ENST00000246174(transcript)|ensembl:ENST00000372742(transcript)|ensembl:ENST00000473968(transcript)|ensembl:ENST00000477663(transcript)|ensembl:ENST00000479502(transcript)|ensembl:ENST00000604957(transcript)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:3UWN1FlZWkUvvF1CIwdnejURUPc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y2X9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-396200|uniprotkb:Q9NY92|uniprotkb:A6NF48|uniprotkb:B3KMX2|uniprotkb:Q5RKW5|intact:EBI-11018373|ensembl:ENSP00000294740|ensembl:ENSP00000356322	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:zn281_human(display_long)|uniprotkb:ZNF281(gene name)|psi-mi:ZNF281(display_short)|uniprotkb:GZP1(gene name synonym)|uniprotkb:ZBP99(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 99(gene name synonym)|uniprotkb:Transcription factor ZBP-99(gene name synonym)|uniprotkb:GC-box-binding zinc finger protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_036614.1|refseq:NP_001268222.1|refseq:NP_001268223.1|refseq:XP_016856376.1|refseq:XP_016856377.1|ensembl:ENSG00000162702(gene)|ensembl:ENST00000294740(transcript)|ensembl:ENST00000367353(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y2X9	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:bjmz9ne6FkC0kbJUv13u8IoDYHM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NNW5	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q7Z5K2	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P45880	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P21796	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y5K5	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95071	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P11441	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356983|uniprotkb:Q5HY80|ensembl:ENSP00000358674	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ubl4a_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)|uniprotkb:GDX(gene name synonym)|uniprotkb:DXS254E(gene name synonym)|uniprotkb:UBL4(gene name synonym)|uniprotkb:Ubiquitin-like protein GDX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055050.1|ensembl:ENSG00000102178(gene)|ensembl:ENST00000369660(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016020"(membrane)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|mint:P11441|rcsb pdb:2DZI|rcsb pdb:4WWR|rcsb pdb:4X86|reactome:R-HSA-9609523	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:euKOrDRC1mx0s2QVY95010PRaIg9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q5JTV8	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2559665|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|ensembl:ENSP00000476687	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_056417.2|ensembl:ENSG00000143337(gene)|ensembl:ENST00000606911(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0051117"(ATPase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|dip:DIP-56692N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:qFH5HTm3fcIwmGL486H8IqZHG489606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P42166	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9HC07	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-3920600|uniprotkb:B4DHW1|ensembl:ENSP00000370736|uniprotkb:Q9BTN9|uniprotkb:A8K3P8|uniprotkb:Q9NZ34	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tm165_human(display_long)|uniprotkb:TMEM165(gene name)|psi-mi:TMEM165(display_short)|uniprotkb:TPARL(gene name synonym)|uniprotkb:Transmembrane protein PT27(gene name synonym)|uniprotkb:Transmembrane protein TPARL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000134851(gene)|ensembl:ENST00000381334(transcript)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032468"(Golgi calcium ion homeostasis)|go:"GO:0032472"(Golgi calcium ion transport)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046873"(metal ion transmembrane transporter activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071421"(manganese ion transmembrane transport)|interpro:IPR001727(Protein of unknown function UPF0016)|mint:Q9HC07|refseq:NP_060945.2|refseq:XP_016863901.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ldHk1rPCEZrMLw8Pj6zVshPaNw09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y4R8	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1043674|uniprotkb:O75168|uniprotkb:Q7LDV4|uniprotkb:Q9BR21|intact:EBI-725566|intact:EBI-1047721|ensembl:ENSP00000262319|uniprotkb:D3DU73	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:telo2_human(display_long)|uniprotkb:TELO2(gene name)|psi-mi:TELO2(display_short)|uniprotkb:KIAA0683(gene name synonym)|uniprotkb:Protein clk-2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000100726(gene)|ensembl:ENST00000262319(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070209"(ASTRA complex)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019337|interpro:IPR038528|mint:Q9Y4R8|rcsb pdb:4PSI|refseq:NP_057195.2|refseq:XP_016879403.1|dip:DIP-40568N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:AnKk5b5Bc/tzEEz+p68m5uQUZVY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P17987	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q15170	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2511314|uniprotkb:Q9UJQ9|intact:EBI-11156070	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcal1_human(display_long)|uniprotkb:TCEAL1(gene name)|psi-mi:TCEAL1(display_short)|uniprotkb:SIIR(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein-like 1(gene name synonym)|uniprotkb:Nuclear phosphoprotein p21/SIIR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR021156|interpro:IPR010370(Transcription elongation factor A, SII-related)|mint:Q15170	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:QGQDFZmacLSo79K+UBfW/ulS32E9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O60232	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q04837	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q13501	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O15269	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q6P1M0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q15758	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P53985	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9BV68	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357322|ensembl:ENSP00000292363|uniprotkb:Q9NWX1|intact:EBI-11064977	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rn126_human(display_long)|uniprotkb:RNF126(gene name)|psi-mi:RNF126(display_short)|uniprotkb:RING finger protein 126(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000070423(gene)|ensembl:ENST00000292363(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039525|interpro:IPR039571|interpro:IPR039572|rcsb pdb:2N9O|rcsb pdb:2N9P|reactome:R-HSA-983168|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|refseq:NP_919442.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:4Z4AJGHJgoIUp9zhtfWcFBF1Fxw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P04049	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P54727	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q86YD1	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-722211|uniprotkb:Q6UXX7|uniprotkb:Q96BU3|uniprotkb:Q9HBN4|uniprotkb:Q9NYL1|ensembl:ENSP00000375717|ensembl:ENSP00000469128|ensembl:ENSP00000472816	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ptov1_human(display_long)|uniprotkb:Activator interaction domain-containing protein 2(gene name synonym)|uniprotkb:PP642(orf name)|uniprotkb:UNQ6127/PRO20092(orf name)|uniprotkb:PTOV1(gene name)|psi-mi:PTOV1(display_short)|uniprotkb:ACID2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_059128.2|refseq:NP_001292034.1|refseq:NP_001292037.1|ensembl:ENSG00000104960(gene)|ensembl:ENST00000391842(transcript)|ensembl:ENST00000599732(transcript)|ensembl:ENST00000601675(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR021394|interpro:IPR038196|mint:Q86YD1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:IHNzBJdo2bMbeep+32jeZct4czM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P61289	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P51665	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q15008	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O43242	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q13200	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O00231	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:BgQKXK7gMMihacRCI+g/pBnRN309606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q99460	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P62333	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P62191	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P13861	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P50897	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1237011|intact:EBI-2859371|uniprotkb:Q6FGQ4|uniprotkb:B4DY24|ensembl:ENSP00000432053|ensembl:ENSP00000493153	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ppt1_human(display_long)|uniprotkb:PPT1(gene name)|psi-mi:PPT1(display_short)|uniprotkb:PPT(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)|uniprotkb:CLN1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_000301.1|refseq:NP_001136076.1|ensembl:ENSG00000131238(gene)|ensembl:ENST00000529905(transcript)|ensembl:ENST00000642050(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007625"(grooming behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016790"(thiolester hydrolase activity)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031579"(membrane raft organization)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050896"(response to stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120146"(sulfatide binding)|interpro:IPR002472(Palmitoyl protein thioesterase)|interpro:IPR029058|interpro:IPR030294|mint:P50897|rcsb pdb:3GRO|reactome:R-HSA-75105|go:"GO:0043524"(negative regulation of neuron apoptotic process)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:2G1ae6m4OZsMiRzro/2JmWiOOMA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q13136	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P52434	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P19387	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P24928	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O15160	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P28340	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O15212	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957	-	-	crc64:8F138EAAE512A312	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9BSD7	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2689235|ensembl:ENSP00000355587	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_115700.1|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|ensembl:ENSG00000135778(gene)|ensembl:ENST00000366628(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|refseq:NP_001316382.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O96000	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q13772	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-954501|uniprotkb:Q14239|uniprotkb:B4E260|uniprotkb:E9PAV7|uniprotkb:J3KQN8|intact:EBI-28971630|ensembl:ENSP00000462943|ensembl:ENSP00000463476|ensembl:ENSP00000464054|uniprotkb:A8K8W5	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ncoa4_human(display_long)|uniprotkb:Androgen receptor-associated protein of 70 kDa(gene name synonym)|uniprotkb:Ret-activating protein ELE1(gene name synonym)|uniprotkb:NCOA4(gene name)|psi-mi:NCOA4(display_short)|uniprotkb:ARA70(gene name synonym)|uniprotkb:ELE1(gene name synonym)|uniprotkb:RFG(gene name synonym)|uniprotkb:Androgen receptor coactivator 70 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENST00000578454|ensembl:ENSP00000463027|ensembl:ENST00000579039|ensembl:ENSP00000463455|ensembl:ENSP00000462943|ensembl:ENSP00000463476|ensembl:ENSP00000464054|refseq:NP_001138732.1|refseq:NP_001138734.1|refseq:NP_001138735.1|refseq:NP_005428.1|ensembl:ENSG00000266412(gene)|ensembl:ENST00000581486(transcript)|ensembl:ENST00000583565(transcript)|ensembl:ENST00000585132(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008584"(male gonad development)|go:"GO:0009725"(response to hormone)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0044754"(autolysosome)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|interpro:IPR022174|interpro:IPR039947|rcsb pdb:1T5Z|refseq:NP_001138733.1|dip:DIP-5957N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:/NfEP88wxWvTac5UcLWx2WJend89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O75592	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NYP9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P33993	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P33991	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q16659	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UNF1	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439|ensembl:ENSP00000364193|ensembl:ENSP00000364198|ensembl:ENSP00000364209|ensembl:ENSP00000379526	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|ensembl:ENSG00000102316(gene)|ensembl:ENST00000218439(transcript)|ensembl:ENST00000375053(transcript)|ensembl:ENST00000375058(transcript)|ensembl:ENST00000375068(transcript)|ensembl:ENST00000396224(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0016020"(membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR028810|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|dip:DIP-50722N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:fXavezmKy58aGuVgzvDYjwNw3B89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y5V3	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O14654	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P51617	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95163	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q92598	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P11142	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P34932	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q6YN16	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1056665|uniprotkb:A8K1L4|uniprotkb:A8K8X1|uniprotkb:A8MSV3|uniprotkb:Q658M8|uniprotkb:Q9BT58|ensembl:ENSP00000381785	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hsdl2_human(display_long)|uniprotkb:HSDL2(gene name)|psi-mi:HSDL2(display_short)|uniprotkb:C9orf99(gene name synonym)|uniprotkb:SDR13C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 13C member 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001182751.1|refseq:NP_115679.2|ensembl:ENSG00000119471(gene)|ensembl:ENST00000398805(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR036291|interpro:IPR036527|rcsb pdb:3KVO	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:9p5t2957ZP6MwNTNgdfX0rUepnI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9HCN4	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q7L5D6	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-711823|uniprotkb:A4D2Q1|uniprotkb:B3KNC7|uniprotkb:Q9UFC9|uniprotkb:Q9Y309|ensembl:ENSP00000265857	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:get4_human(display_long)|uniprotkb:CEE(gene name synonym)|uniprotkb:Conserved edge-expressed protein(gene name synonym)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:CGI-20(orf name)|uniprotkb:C7orf20(gene name synonym)|uniprotkb:TRC35(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 35 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000239857(gene)|ensembl:ENST00000265857(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0051087"(chaperone binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q7L5D6|rcsb pdb:6AU8|reactome:R-HSA-9609523|refseq:NP_057033.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:WbZJTGrC2/fB4iOFLJYn9MIWZFA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y285	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8WVX9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NVI1	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y4C2	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-750484|uniprotkb:Q9BW63|intact:EBI-954169|uniprotkb:A8K6E0|uniprotkb:Q75KM8|uniprotkb:Q75KM9|uniprotkb:Q7L665|ensembl:ENSP00000419235	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcaf1_human(display_long)|uniprotkb:TCAF1(gene name)|psi-mi:TCAF1(display_short)|uniprotkb:FAM115A(gene name synonym)|uniprotkb:KIAA0738(gene name synonym)|uniprotkb:TRP channel-associated factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001193867.1|refseq:NP_001193870.1|refseq:NP_055534.1|refseq:XP_005250131.1|refseq:XP_005250132.1|refseq:XP_005250133.1|refseq:XP_005250134.1|refseq:XP_006716254.1|refseq:XP_006716255.1|refseq:XP_016868322.1|refseq:XP_016868323.1|refseq:XP_016868324.1|refseq:XP_016868325.1|ensembl:ENSG00000198420(gene)|ensembl:ENST00000479870(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901529"(positive regulation of anion channel activity)|interpro:IPR029062|interpro:IPR031161|interpro:IPR035423|interpro:IPR042279	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:krj5GKiU60IW49DV76f4FWG3RHE9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9H6Z9	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O75521	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2512024|ensembl:ENSP00000369461|uniprotkb:Q9NYH7|uniprotkb:Q9NQH1|uniprotkb:Q9H0T9|uniprotkb:Q5JYK7|uniprotkb:Q7L124|uniprotkb:Q9UN55|uniprotkb:Q9BUE9|uniprotkb:Q8N0X0|uniprotkb:Q5JYK5|intact:EBI-2802486	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:eci2_human(display_long)|uniprotkb:ECI2(gene name)|psi-mi:ECI2(display_short)|uniprotkb:DRS1(gene name synonym)|uniprotkb:HCA88(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Diazepam-binding inhibitor-related protein 1(gene name synonym)|uniprotkb:DRS-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 88(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-1(gene name synonym)|uniprotkb:PECI(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000198721(gene)|ensembl:ENST00000380118(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:O75521|rcsb pdb:2CQU|rcsb pdb:2F6Q|rcsb pdb:4U18|rcsb pdb:4U19|rcsb pdb:4U1A|reactome:R-HSA-390247|reactome:R-HSA-9033241|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|refseq:NP_001159482.1|refseq:NP_006108.2|refseq:NP_996667.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:AIR8lybsBusmVmjgsN0Hcl6p+3g9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95905	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P63167	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q96EY1	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P35222	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9Y6K0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1237183|uniprotkb:Q69YJ9|uniprotkb:Q9P0Y8|ensembl:ENSP00000349696|ensembl:ENSP00000441980	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cept1_human(display_long)|uniprotkb:CEPT1(gene name)|psi-mi:CEPT1(display_short)|uniprotkb:1-alkenyl-2-acylglycerol choline phosphotransferase(gene name synonym)|uniprotkb:PRO1101(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001007795.1|refseq:NP_006081.1|refseq:NP_001317672.1|ensembl:ENSG00000134255(gene)|ensembl:ENST00000357172(transcript)|ensembl:ENST00000545121(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047359"(1-alkenyl-2-acylglycerol choline phosphotransferase activity)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-HSA-1483191|reactome:R-HSA-1483213	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:M5xOOr596HTYFySYQ0c2LgyK5Pc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q5SW79	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O00311	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-374980|uniprotkb:O00558|uniprotkb:Q5T5U5|ensembl:ENSP00000234626|ensembl:ENSP00000393139|uniprotkb:D3DT31	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cdc7_human(display_long)|uniprotkb:CDC7(gene name)|psi-mi:CDC7(display_short)|uniprotkb:CDC7L1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	rcsb pdb:5UWR|rcsb pdb:6YA6|rcsb pdb:6YA7|rcsb pdb:6YA8|reactome:R-HSA-176187|reactome:R-HSA-68962|reactome:R-HSA-8953750|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O00311|rcsb pdb:4F99|rcsb pdb:4F9A|rcsb pdb:4F9B|rcsb pdb:4F9C|rcsb pdb:5UWQ|ensembl:ENSG00000097046(gene)|ensembl:ENST00000234626(transcript)|ensembl:ENST00000428239(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|refseq:NP_001127891.1|refseq:NP_001127892.1|refseq:NP_003494.1|refseq:XP_005271298.1|dip:DIP-31728N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:p5yHRwdn0crHmH8EXAFyM5R0xwM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P60953	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q99832	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P40227	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O60563	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P51587	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P46379	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O14965	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UI12	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P36542	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P06576	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P25705	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P54709	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P05023	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q8IZT6	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1057621|uniprotkb:Q4G1H1|uniprotkb:Q86UX4|uniprotkb:Q8IUL2|uniprotkb:Q8IZJ7|uniprotkb:Q8IZJ8|uniprotkb:Q8IZJ9|uniprotkb:Q8N4D1|uniprotkb:Q9NVS1|uniprotkb:Q9NVT6|uniprotkb:Q5VYL3|ensembl:ENSP00000356379	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:aspm_human(display_long)|uniprotkb:ASPM(gene name)|psi-mi:ASPM(display_short)|uniprotkb:MCPH5(gene name synonym)|uniprotkb:Abnormal spindle protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001193775.1|refseq:NP_060606.3|go:"GO:0048477"(oogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0051653"(spindle localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR029955|interpro:IPR031549|interpro:IPR036872|go:"GO:0045769"(negative regulation of asymmetric cell division)|ensembl:ENSG00000066279(gene)|ensembl:ENST00000367409(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007051"(spindle organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021873"(forebrain neuroblast division)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030496"(midbody)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0045665"(negative regulation of neuron differentiation)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:DQbMaRaMAJI7beVJKAmBgsXgeCo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O43681	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NP61	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2875816|ensembl:ENSP00000263245|uniprotkb:Q9Y4V4|uniprotkb:Q9NUP5|uniprotkb:Q9Y4V3|uniprotkb:Q9NT10|uniprotkb:Q9BSC6|uniprotkb:Q9H9J0|uniprotkb:E9PB03	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:arfg3_human(display_long)|uniprotkb:ARFGAP3(gene name)|psi-mi:ARFGAP3(display_short)|uniprotkb:ARFGAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000242247(gene)|ensembl:ENST00000263245(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:2CRW|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-9013148|reactome:R-HSA-9013408|go:"GO:0005096"(GTPase activator activity)|refseq:NP_001135765.1|refseq:NP_055385.3	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:1868s5elsn/sX/f8if3lmbLxKxg9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O14617	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003929.4|refseq:NP_001248755.1|ensembl:ENSG00000065000(gene)|ensembl:ENST00000345016(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|dip:DIP-46793N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q16186	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O95573	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|ensembl:ENSP00000350012|ensembl:ENSP00000375918|ensembl:ENSP00000504861|ensembl:ENSP00000504907|ensembl:ENSP00000505400|ensembl:ENSP00000505654|ensembl:ENSP00000505793|ensembl:ENSP00000505856|ensembl:ENSP00000505940|ensembl:ENSP00000506361|ensembl:ENSP00000506468|intact:EBI-21359981	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|ensembl:ENSG00000123983(gene)|ensembl:ENST00000357430(transcript)|ensembl:ENST00000392066(transcript)|ensembl:ENST00000679514(transcript)|ensembl:ENST00000679558(transcript)|ensembl:ENST00000680147(transcript)|ensembl:ENST00000680251(transcript)|ensembl:ENST00000680395(transcript)|ensembl:ENST00000680684(transcript)|ensembl:ENST00000680921(transcript)|ensembl:ENST00000681383(transcript)|ensembl:ENST00000681697(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9H992	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-949983|ensembl:ENSP00000386830|ensembl:ENSP00000259050|uniprotkb:Q53GQ1|uniprotkb:Q9BTR9|uniprotkb:A8K9X1|uniprotkb:D3DPB0|uniprotkb:B7Z7P5	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:marh7_human(display_long)|uniprotkb:MARCHF7(gene name)|psi-mi:MARCHF7(display_short)|uniprotkb:AXOT(gene name synonym)|uniprotkb:Axotrophin(gene name synonym)|uniprotkb:MARCH7(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 7(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VII(gene name synonym)|uniprotkb:RING finger protein 177(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF7(gene name synonym)|uniprotkb:RNF177(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001269734.1|refseq:NP_001269735.1|refseq:NP_001269736.1|ensembl:ENST00000259050(transcript)|ensembl:ENST00000409175(transcript)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016740"(transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050821"(protein stabilization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|ensembl:ENSG00000136536(gene)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_073737.1|refseq:XP_005246830.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:HT4KtjhOVdeP4mam5eQhgX+ib5A9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q05086	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UM00	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1051217|uniprotkb:O75545|uniprotkb:Q9BZS3|uniprotkb:Q9BZU8|uniprotkb:B2REA0|ensembl:ENSP00000480514|uniprotkb:J9JIE6	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tmco1_human(display_long)|uniprotkb:Transmembrane and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Xenogeneic cross-immune protein PCIA3(gene name synonym)|uniprotkb:Transmembrane and coiled-coil domains protein 4(gene name synonym)|uniprotkb:TMCO1(gene name)|psi-mi:TMCO1(display_short)|uniprotkb:PNAS-10(orf name)|uniprotkb:PNAS-136(orf name)|uniprotkb:UNQ151/PRO177(orf name)|uniprotkb:TMCC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_061899.2|ensembl:ENSG00000143183(gene)|ensembl:ENST00000612311(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006983"(ER overload response)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0043022"(ribosome binding)|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008559(Protein of unknown function DUF841, eukaryotic)|rcsb pdb:6W6L	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:AGRI6UgUEOjrVCi0laVQPtfaHRU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UNE7	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P05141	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q00325	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UJS0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q02978	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P55036	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O00487	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9UNM6	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:iOxE62MMeGx+aqsrir/LukJqeho9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P62195	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	-	crc64:29C6410C4A85A7F7	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P43686	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P17980	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P35998	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P30876	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O75489	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408	-	-	crc64:C058D62779BEF17B	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9P032	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O00483	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q15773	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O00165	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q96CS3	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q99615	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O75190	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NXW2	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:O60884	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P31689	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P50990	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P50991	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P49368	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P78371	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P27708	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:Q9NVI7	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:IZKJEVLLS/DFINgBgO5frizN1P49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:P28288	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:M0QYT0	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-12502729|ensembl:ENSP00000470059	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:m0qyt0_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000268083(gene)|ensembl:ENST00000594769(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001753(Crotonase, core)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029045|interpro:IPR034816|interpro:IPR035979	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:5AdJb7A6Ayo1STGOHBl+RTKwZ6c9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16659	uniprotkb:H3BN98	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-10977767|ensembl:ENSP00000454746	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:h3bn98_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12502733|imex:IM-22750-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000260342(gene)|ensembl:ENST00000567078(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000630(Ribosomal protein S8)|interpro:IPR035987	-	-	-	figure legend:Table S4|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: SLC25A6,SLC25A4 (UniProtKB accessions: P12235;P12236); GNAS (UniProtKB accessions: P63092;Q5JWF2); HLA-C (UniProtKB accessions: P10321;P30499;P30504;P30505;P30508;P30510;Q07000;Q29865;Q29960;Q29963;Q95604); ARAF,BRAF (UniProtKB accessions: P10398;P15056); ATP5E,ATP5EP2 (UniProtKB accessions: P56381;Q5VTU8); GNB1,GNB2,GNB4 (UniProtKB accessions: P62873;P62879;Q9HAV0); HSPA6,HSPA7 (UniProtKB accessions: P17066;P48741); SAR1A,SAR1B (UniProtKB accessions: Q9NR31;Q9Y6B6); SLC25A22,SLC25A18 (UniProtKB accessions: Q9H1K4;Q9H936); ST13,ST13P5,ST13P4 (UniProtKB accessions: P50502;Q8IZP2;Q8NFI4); UBA52,UBC,UBB (UniProtKB accessions: P0CG47;P0CG48;P62987). Additionally, these preys were also not entered since they were identified with UniProt accessions of cow proteins: CON__P17697,CON__P81644,CON__Q1A7A4."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/11/30	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:fDimE+pwgd8trkWNk8fV9qRksrc9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O75717	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-3951691|ensembl:ENSP00000353793|uniprotkb:C9JW18|uniprotkb:F6W0U7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:wdhd1_human(display_long)|uniprotkb:WDHD1(gene name)|psi-mi:WDHD1(display_short)|uniprotkb:AND1(gene name synonym)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000198554(gene)|ensembl:ENST00000360586(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR001680(WD40 repeat)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR022100|interpro:IPR024977|interpro:IPR036322|interpro:IPR036910|rcsb pdb:2D7L|rcsb pdb:5GVA|rcsb pdb:5GVB|rcsb pdb:5OGS|rcsb pdb:6XTY|refseq:NP_001008397.1|refseq:NP_009017.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:SNbJutgOfo9kguAoOv5Hdhk5s+k9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13472	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q562F6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-989213|ensembl:ENSP00000350447|uniprotkb:Q53RR9|uniprotkb:Q53T20|uniprotkb:Q86XY4|uniprotkb:Q8IWK2|uniprotkb:Q8IZK1|uniprotkb:Q8N1Q5|uniprotkb:Q96LQ3|intact:EBI-2559582	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sgo2_human(display_long)|uniprotkb:SGO2(gene name)|psi-mi:SGO2(display_short)|uniprotkb:Shugoshin-2(gene name synonym)|uniprotkb:Shugoshin-like 2(gene name synonym)|uniprotkb:Tripin(gene name synonym)|uniprotkb:SGOL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000163535(gene)|ensembl:ENST00000357799(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0030892"(mitotic cohesin complex)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR026706|interpro:IPR038889|mint:Q562F6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:XP_011509036.1|refseq:NP_001153518.1|refseq:NP_689737.4|refseq:XP_005246402.1|dip:DIP-36615N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:lj8jTnNLhIEEqgqjvOrIJIS57yc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H9A7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q15032	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2267290|uniprotkb:Q8IW32|uniprotkb:G5E9G8|uniprotkb:A8K1V0|uniprotkb:B3KXQ9|uniprotkb:E9PBB4|uniprotkb:E9PG42|ensembl:ENSP00000264160	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:r3hd1_human(display_long)|uniprotkb:R3HDM1(gene name)|psi-mi:R3HDM1(display_short)|uniprotkb:KIAA0029(gene name synonym)|uniprotkb:R3HDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001269727.1|refseq:NP_001269728.1|refseq:NP_001269729.1|refseq:XP_006712452.1|refseq:XP_016859207.1|refseq:NP_056176.2|ensembl:ENSP00000264160|ensembl:ENST00000409478|ensembl:ENSP00000386457|ensembl:ENST00000409606|ensembl:ENSP00000387010|ensembl:ENST00000410054|ensembl:ENSP00000386877|ensembl:ENST00000628915|ensembl:ENSP00000486837|ensembl:ENSG00000048991(gene)|ensembl:ENST00000264160(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR024771|interpro:IPR036867|mint:Q15032	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:TtKztiVREzd5YahM/O6ai/NLDE89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P10644	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H081	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P41212	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1372759|uniprotkb:A3QVP6|uniprotkb:Q9UMF6|uniprotkb:Q9UMF7|uniprotkb:Q9UMG0|uniprotkb:A8K076|ensembl:ENSP00000379658	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:etv6_human(display_long)|uniprotkb:ETS translocation variant 6(gene name synonym)|uniprotkb:ETS-related protein Tel1(gene name synonym)|uniprotkb:ETV6(gene name)|psi-mi:ETV6(display_short)|uniprotkb:TEL(gene name synonym)|uniprotkb:TEL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001978.1|dip:DIP-17028N|ensembl:ENSG00000139083(gene)|ensembl:ENST00000396373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007296"(vitellogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0097152"(mesenchymal cell apoptotic process)|interpro:IPR000418(Ets)|rcsb pdb:5L0P|rcsb pdb:7JU2|rcsb pdb:7N1O|rcsb pdb:7N2B|reactome:R-HSA-9673768|reactome:R-HSA-9703465|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|mint:P41212|rcsb pdb:1JI7|rcsb pdb:1LKY|rcsb pdb:2DAO|rcsb pdb:2QAR|rcsb pdb:2QB0|rcsb pdb:2QB1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ekItHLbEk2Expb+mR7jHa6dPBo89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H410	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NRR4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-528367|uniprotkb:Q7Z5V2|uniprotkb:Q86YH0|uniprotkb:Q9NW73|uniprotkb:Q9Y2V9|uniprotkb:Q9Y4Y0|intact:EBI-10973107|uniprotkb:E7EMP9|ensembl:ENSP00000339845|ensembl:ENSP00000425979	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rnc_human(display_long)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:DROSHA(gene name)|psi-mi:DROSHA(display_short)|uniprotkb:p241(gene name synonym)|uniprotkb:RNASEN(gene name synonym)|uniprotkb:RN3(gene name synonym)|uniprotkb:RNASE3L(gene name synonym)|uniprotkb:Protein Drosha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001093882.1|refseq:NP_037367.3|refseq:XP_005248348.1|refseq:XP_005248351.1|ensembl:ENSG00000113360(gene)|ensembl:ENST00000344624(transcript)|ensembl:ENST00000511367(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070878"(primary miRNA binding)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR044442|rcsb pdb:2KHX|rcsb pdb:2NA2|rcsb pdb:5B16|rcsb pdb:6LXD|rcsb pdb:6LXE|rcsb pdb:6V5B|rcsb pdb:6V5C|reactome:R-HSA-203927|dip:DIP-33300N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:vHfmSHxD1M/Sh4dbo2S7FBaE+eQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UIV1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q3V6T2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2266839|uniprotkb:A1IGE7|uniprotkb:Q53SF1|uniprotkb:Q581G3|uniprotkb:Q5HYD0|uniprotkb:Q7Z339|uniprotkb:Q7Z3C5|uniprotkb:B7ZM78|uniprotkb:C9JG83|ensembl:ENSP00000410608|ensembl:ENSP00000495919	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:grdn_human(display_long)|uniprotkb:CCDC88A(gene name)|psi-mi:CCDC88A(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:GRDN(gene name synonym)|uniprotkb:KIAA1212(gene name synonym)|uniprotkb:Girders of actin filament(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88A(gene name synonym)|uniprotkb:Akt phosphorylation enhancer(gene name synonym)|uniprotkb:Hook-related protein 1(gene name synonym)|uniprotkb:G alpha-interacting vesicle-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011531267.1|refseq:XP_011531268.1|refseq:XP_011531269.1|refseq:NP_001129069.1|refseq:NP_060554.3|refseq:NP_001241872.1|dip:DIP-50784N|ensembl:ENSG00000115355(gene)|ensembl:ENST00000436346(transcript)|ensembl:ENST00000642200(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030142"(COPI-coated Golgi to ER transport vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0061024"(membrane organization)|go:"GO:1903566"(positive regulation of protein localization to cilium)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027717|interpro:IPR036872|interpro:IPR043936|rcsb pdb:6MHF|reactome:R-HSA-9696264|reactome:R-HSA-9696273|go:"GO:0072660"(maintenance of protein location in plasma membrane)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:6kUpfRsRH31AqsM5d3q6mybkgdw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8NG31	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P54132	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5SYE7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-9640051|uniprotkb:Q5SYE8|uniprotkb:Q3ZCS5|uniprotkb:Q9P2J0|ensembl:ENSP00000394546	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:nhsl1_human(display_long)|uniprotkb:NHSL1(gene name)|psi-mi:NHSL1(display_short)|uniprotkb:C6orf63(gene name synonym)|uniprotkb:KIAA1357(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000343505|ensembl:ENSP00000344672|ensembl:ENSP00000394546|refseq:NP_001137532.1|refseq:NP_065197.1|dip:DIP-47303N|ensembl:ENSG00000135540(gene)|ensembl:ENST00000427025(transcript)|go:"GO:0030154"(cell differentiation)|interpro:IPR024845|mint:Q5SYE7	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:fSt25Mtm6KgIdpf9rD+jhzp4rqo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96T17	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-7850186|ensembl:ENSP00000368972|uniprotkb:Q8N792|uniprotkb:B9EGC7|uniprotkb:Q6PIC7|uniprotkb:Q5JPS7|uniprotkb:Q5EBN1|uniprotkb:C9JMA4|uniprotkb:C9JYW0|uniprotkb:B7Z2J8|intact:MINT-8329993|uniprotkb:B7Z3S7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ma7d2_human(display_long)|uniprotkb:MAP7D2(gene name)|psi-mi:MAP7D2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000184368(gene)|ensembl:ENST00000379651(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR008604(E-MAP-115)|refseq:NP_689993.2|refseq:NP_001161939.1|refseq:NP_001161938.1|refseq:NP_001161937.1	-	-	comment:mint|comment:homomint	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:LkDshaxC+z9vl45KM9TPY59TFoc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P35556	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-6164392|ensembl:ENSP00000424571|ensembl:ENSP00000262464|uniprotkb:B4DU01|uniprotkb:Q59ES6	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:fbn2_human(display_long)|uniprotkb:FBN2(gene name)|psi-mi:FBN2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35556|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|interpro:IPR018097|ensembl:ENSG00000138829(gene)|ensembl:ENST00000262464(transcript)|ensembl:ENST00000508053(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|refseq:NP_001990.2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:iqBnjHuy9kU3serIc5tPWGIDzUc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q02930	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-8636872|ensembl:ENSP00000350359|uniprotkb:Q75N02|uniprotkb:A8KA51|uniprotkb:Q86UJ9|uniprotkb:B5BUH3|uniprotkb:Q06246|intact:MINT-8162615|intact:MINT-267970|uniprotkb:B4DU13|uniprotkb:Q05886|uniprotkb:C9JK47	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:creb5_human(display_long)|uniprotkb:CREB5(gene name)|psi-mi:CREB5(display_short)|uniprotkb:CREBPA(gene name synonym)|uniprotkb:cAMP-response element-binding protein A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000357727(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236|mint:Q02930|ensembl:ENSG00000146592(gene)|refseq:XP_005249963.1|refseq:NP_004895.2|refseq:NP_878901.2|refseq:NP_001011666.1|refseq:NP_878902.2|refseq:XP_016868295.1|refseq:XP_016868297.1	-	-	function:Binds to the cAMP response element and activates transcription	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:v27tGFZeHt18Q8QzT+d8txg6Fhc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8NE35	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-8596191|ensembl:ENSP00000265997|ensembl:ENSP00000482128|uniprotkb:Q9Y2E9|uniprotkb:Q9NQJ7|uniprotkb:Q5T389|intact:UNK-5523090	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cpeb3_human(display_long)|uniprotkb:CPEB3(gene name)|psi-mi:CPEB3(display_short)|uniprotkb:KIAA0940(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000107864(gene)|ensembl:ENST00000265997(transcript)|ensembl:ENST00000614585(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900248"(negative regulation of cytoplasmic translational elongation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032296|interpro:IPR034819|interpro:IPR035979|interpro:IPR038446|mint:Q8NE35|rcsb pdb:2DNL|rcsb pdb:2RUG|go:"GO:0048167"(regulation of synaptic plasticity)|refseq:NP_055727.3|refseq:NP_001171608.1|refseq:XP_005269687.1	-	-	comment:mint	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:WzbauahDDjrcRmf9PCoBmlbSyyI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5VUA4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2849257|uniprotkb:Q8NEM6|uniprotkb:Q9UNU8|uniprotkb:Q4G0E4|uniprotkb:O94796|uniprotkb:Q9Y2W9|intact:EBI-28976662|ensembl:ENSP00000354964	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:zn318_human(display_long)|uniprotkb:ZNF318(gene name)|psi-mi:ZNF318(display_short)|uniprotkb:Endocrine regulatory protein(gene name synonym)|uniprotkb:HRIHFB2436(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000354964|ensembl:ENST00000605935|ensembl:ENSP00000475748|refseq:XP_011512754.1|refseq:NP_055160.2|ensembl:ENSG00000171467(gene)|ensembl:ENST00000361428(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003604(Zinc finger, U1-type)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:HqHWYB1s5uaauSljuYFDb3/6XB49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q7Z3T8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8WW38	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-947213|uniprotkb:Q32MA6|uniprotkb:Q9NPL7|uniprotkb:Q9NPS4|uniprotkb:Q9UNI5|ensembl:ENSP00000384179	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:fog2_human(display_long)|uniprotkb:ZFPM2(gene name)|psi-mi:ZFPM2(display_short)|uniprotkb:FOG2(gene name synonym)|uniprotkb:Zinc finger protein multitype 2(gene name synonym)|uniprotkb:Friend of GATA protein 2(gene name synonym)|uniprotkb:ZNF89B(gene name synonym)|uniprotkb:Zinc finger protein 89B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_036214.2|ensembl:ENSG00000169946(gene)|ensembl:ENST00000407775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003221"(right ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2000195"(negative regulation of female gonad development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034731|interpro:IPR036236|interpro:IPR039746|mint:Q8WW38|reactome:R-HSA-9690406|reactome:R-HSA-983231	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:FWix1ZWjYT7tMDfaS5p10SJ7mE49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H2Y7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1211501|uniprotkb:Q6NSD9|uniprotkb:Q6PEK1|uniprotkb:Q86T43|uniprotkb:Q86T45|uniprotkb:Q86T50|uniprotkb:Q86T58|uniprotkb:Q86TA9|uniprotkb:Q96M37|uniprotkb:Q9H7B8|uniprotkb:B4DZ40|uniprotkb:E9PE29|ensembl:ENSP00000263805	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:zn106_human(display_long)|uniprotkb:ZNF106(gene name)|psi-mi:ZNF106(display_short)|uniprotkb:SH3BP3(gene name synonym)|uniprotkb:ZFP106(gene name synonym)|uniprotkb:ZNF474(gene name synonym)|uniprotkb:Zinc finger protein 474(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001271235.1|refseq:NP_001271236.1|refseq:NP_071918.1|ensembl:ENSG00000103994(gene)|ensembl:ENST00000263805(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR042622	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:LdsJljbFU6M/RNAXcVwLx8TtOCk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96DT7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-10235384|uniprotkb:Q8IXI9|uniprotkb:Q96MH9|uniprotkb:Q86W96|uniprotkb:A4FVD0|ensembl:ENSP00000387462|ensembl:ENSP00000412036	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:zbt10_human(display_long)|uniprotkb:ZBTB10(gene name)|psi-mi:ZBTB10(display_short)|uniprotkb:RINZF(gene name synonym)|uniprotkb:RINZFC(gene name synonym)|uniprotkb:Zinc finger protein RIN ZF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001099009.1|refseq:NP_001264074.1|refseq:NP_076418.3|ensembl:ENSG00000205189(gene)|ensembl:ENST00000430430(transcript)|ensembl:ENST00000455036(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96DT7	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:wGypJaZ9a4cfN5Z84Aof+MAruSI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y2K1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P46937	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6PJI9	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2515073|intact:EBI-28967178|ensembl:ENSP00000262144|uniprotkb:Q9HA43|uniprotkb:Q96PW5|uniprotkb:B3KRC3|uniprotkb:Q9BSW6|uniprotkb:Q71RE7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:wdr59_human(display_long)|uniprotkb:WDR59(gene name)|psi-mi:WDR59(display_short)|uniprotkb:KIAA1923(gene name synonym)|uniprotkb:WD repeat-containing protein 59(gene name synonym)|uniprotkb:FP977(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000262144|ensembl:ENST00000616369|ensembl:ENSP00000482446|ensembl:ENSG00000103091(gene)|ensembl:ENST00000262144(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0061700"(GATOR2 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR006575(RWD)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039456|reactome:R-HSA-9639288|mint:Q6PJI9|refseq:NP_001311100.1|refseq:NP_085058.3	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:7yMOhbv8kjVuL8I+Zs+8fLF933k9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q7Z5K2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q14135	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-5278589|uniprotkb:B4DTS7|uniprotkb:Q7L5V0|uniprotkb:Q9BQ78|uniprotkb:J3KN68	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:vgll4_human(display_long)|uniprotkb:VGLL4(gene name)|psi-mi:VGLL4(display_short)|uniprotkb:KIAA0121(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001121691.1|refseq:NP_001121693.1|refseq:NP_001271319.1|refseq:NP_001271320.1|refseq:NP_001121692.1|refseq:NP_055482.2|interpro:IPR006627(Protein of unknown function TDU)|interpro:IPR028184|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005634"(nucleus)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:uV9rqVyw0SMHZrHZTyzqkg3ovEw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:A8MV65	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-12503144|ensembl:ENSP00000381436|uniprotkb:D3DU37|uniprotkb:Q504T7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:vgll3_human(display_long)|uniprotkb:VGLL3(gene name)|psi-mi:VGLL3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000206538(gene)|ensembl:ENST00000398399(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006627(Protein of unknown function TDU)|interpro:IPR011520(Vestigial/tondu)|refseq:NP_001307422.1|refseq:NP_057290.2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:lCqw7ijEyXwy7WCCWS62mkIh6Oo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P46939	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q70EL1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 54(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_689799.3|refseq:NP_001307366.1|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|ensembl:ENSG00000166348(gene)|ensembl:ENST00000339859(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR040142|mint:Q70EL1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5T6F2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2514383|ensembl:ENSP00000368540|ensembl:ENSP00000507293|ensembl:ENSP00000508372|uniprotkb:Q5JV03|uniprotkb:Q9P237|uniprotkb:Q8NC94|uniprotkb:Q6PK34|uniprotkb:Q2M2R4	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ubap2_human(display_long)|uniprotkb:UBAP2(gene name)|psi-mi:UBAP2(display_short)|uniprotkb:KIAA1491(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001269458.1|refseq:NP_060919.3|ensembl:ENSG00000137073(gene)|ensembl:ENST00000379238(transcript)|ensembl:ENST00000682239(transcript)|ensembl:ENST00000684158(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045296"(cadherin binding)|go:"GO:0005634"(nucleus)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|refseq:NP_001269459.1|ensembl:ENSP00000368540|ensembl:ENSP00000507293|ensembl:ENSP00000508372	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:0bcavAC5MrP55wijYi8LYZbT6ys9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96CW5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1046278|ensembl:ENSP00000261965|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007338"(single fertilization)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q96CW5|rcsb pdb:6V6B|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSG00000126216(gene)|ensembl:ENST00000261965(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000923"(equatorial microtubule organizing center)|refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96AE7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11017708|uniprotkb:Q8NEC0|uniprotkb:G3XAB3|ensembl:ENSP00000039989	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ttc17_human(display_long)|uniprotkb:TTC17(gene name)|psi-mi:TTC17(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001294872.1|refseq:NP_060729.2|ensembl:ENSG00000052841(gene)|ensembl:ENST00000039989(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0044782"(cilium organization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:4J0w1d572WZqkCyJRcPn5Ij1IzA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8NBP0	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11333658|uniprotkb:Q8ND20|uniprotkb:B1AQI2|uniprotkb:B1AQI1|uniprotkb:Q8IVP8|uniprotkb:Q8NBI0|ensembl:ENSP00000355621	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ttc13_human(display_long)|uniprotkb:TTC13(gene name)|psi-mi:TTC13(display_short)|uniprotkb:PSEC0076(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001116307.2|refseq:NP_078801.3|ensembl:ENSG00000143643(gene)|ensembl:ENST00000366661(transcript)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:KqQvqmp61Rel7qfvU+w4Zmv2sC89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q12815	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2349743|uniprotkb:Q8N5B2|uniprotkb:F8VSF9|uniprotkb:Q6PJU7|ensembl:ENSP00000257909	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:troap_human(display_long)|uniprotkb:TROAP(gene name)|psi-mi:TROAP(display_short)|uniprotkb:Trophinin-assisting protein(gene name synonym)|uniprotkb:Trophinin-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011536027.1|refseq:NP_001094090.1|refseq:NP_005471.3|refseq:NP_001265253.1|dip:DIP-52951N|ensembl:ENSG00000135451(gene)|ensembl:ENST00000257909(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|interpro:IPR026133|mint:Q12815	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:9+3f9EdjzudEOEIYnDMmZGrjjKA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q92547	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P42166	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q92545	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2681976|ensembl:ENSP00000186436	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tm131_human(display_long)|uniprotkb:KIAA0257(gene name synonym)|uniprotkb:RW1(gene name synonym)|uniprotkb:Protein RW1(gene name synonym)|uniprotkb:TMEM131(gene name)|psi-mi:TMEM131(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_056163.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR022113|interpro:IPR039877|ensembl:ENSG00000075568(gene)|ensembl:ENST00000186436(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:wTdksy19YsrD0HErJMPgrldzwTg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q7Z2Z1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11097738|uniprotkb:Q8N4X8|uniprotkb:Q8NCH6|uniprotkb:B2RE07|uniprotkb:B3KVV9|uniprotkb:D3IUT4|uniprotkb:Q9BU55|ensembl:ENSP00000268138	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ticrr_human(display_long)|uniprotkb:TICRR(gene name)|psi-mi:TICRR(display_short)|uniprotkb:C15orf42(gene name synonym)|uniprotkb:TopBP1-interacting checkpoint and replication regulator(gene name synonym)|uniprotkb:TopBP1-interacting, replication-stimulating protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001294954.1|refseq:NP_689472.3|ensembl:ENSG00000140534(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026153|interpro:IPR032746|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000268138(transcript)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gb8h9iKpxiRHMbJEmRW1d2Sx/7g9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6N021	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-310727|uniprotkb:B5MDU0|uniprotkb:Q2TB88|uniprotkb:Q3LIB8|uniprotkb:Q96JX5|uniprotkb:Q9NXW0|uniprotkb:Q9HCM6|intact:EBI-2824636|ensembl:ENSP00000369351|ensembl:ENSP00000442788	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tet2_human(display_long)|uniprotkb:TET2(gene name)|psi-mi:TET2(display_short)|uniprotkb:KIAA1546(gene name synonym)|uniprotkb:Nbla00191(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001120680.1|refseq:NP_060098.3|refseq:XP_005263139.1|ensembl:ENSG00000168769(gene)|ensembl:ENST00000380013(transcript)|ensembl:ENST00000540549(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006211"(5-methylcytosine catabolic process)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070579"(methylcytosine dioxygenase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR024779|interpro:IPR040175|mint:Q6N021|rcsb pdb:4NM6|rcsb pdb:5D9Y|rcsb pdb:5DEU|reactome:R-HSA-5221030	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:/NfgfLFy2v4y6V3rTQ+CWo7Uq/49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P15923	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O60907	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-3505105|uniprotkb:A8K044|uniprotkb:A8K4J7|uniprotkb:Q86UY2|ensembl:ENSP00000385988|ensembl:ENSP00000493782|ensembl:ENSP00000495556|ensembl:ENSP00000496215	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tbl1x_human(display_long)|uniprotkb:TBL1X(gene name)|psi-mi:TBL1X(display_short)|uniprotkb:TBL1(gene name synonym)|uniprotkb:SMAP55(gene name synonym)|uniprotkb:Transducin beta-like protein 1X(gene name synonym)|uniprotkb:Transducin-beta-like protein 1, X-linked(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011543873.1|refseq:NP_001132938.1|refseq:NP_001132939.1|refseq:NP_001132940.1|refseq:NP_005638.1|ensembl:ENSG00000101849(gene)|ensembl:ENST00000407597(transcript)|ensembl:ENST00000645353(transcript)|ensembl:ENST00000645686(transcript)|ensembl:ENST00000646640(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006508"(proteolysis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2XTC|rcsb pdb:2XTD|rcsb pdb:2XTE|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|dip:DIP-60532N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:SQV81eLzdxXuG1b7Kof8190KyyU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:A7MCY6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-359969|uniprotkb:Q14DW3|uniprotkb:O94873|uniprotkb:B2RZG6|ensembl:ENSP00000354777	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tbkb1_human(display_long)|uniprotkb:TBKBP1(gene name)|psi-mi:TBKBP1(display_short)|uniprotkb:SINTBAD(gene name synonym)|uniprotkb:KIAA0775(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_055541.1|ensembl:ENSG00000198933(gene)|ensembl:ENST00000361722(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR024581|interpro:IPR041641|mint:A7MCY6|refseq:XP_005257916.1|refseq:XP_005257917.1|refseq:XP_005257918.1|refseq:XP_005257919.1|dip:DIP-27604N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Hf7hEVRztbT681BKO7sMjh1EwX09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UHD2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-356402|intact:EBI-5773956|intact:EBI-1383470|uniprotkb:Q8IYV3|uniprotkb:Q9NUJ5|ensembl:ENSP00000329967|ensembl:ENSP00000498995|uniprotkb:A8K4S4	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tbk1_human(display_long)|uniprotkb:TBK1(gene name)|psi-mi:TBK1(display_short)|uniprotkb:NAK(gene name synonym)|uniprotkb:TANK-binding kinase 1(gene name synonym)|uniprotkb:T2K(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_037386.1|go:"GO:0004672"(protein kinase activity)|ensembl:ENSG00000183735(gene)|ensembl:ENST00000331710(transcript)|ensembl:ENST00000650790(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901214"(regulation of neuron death)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR041087|interpro:IPR041309|mint:Q9UHD2|rcsb pdb:4EFO|rcsb pdb:4EUT|rcsb pdb:4EUU|rcsb pdb:4IM0|rcsb pdb:4IM2|rcsb pdb:4IM3|rcsb pdb:4IW0|rcsb pdb:4IWO|rcsb pdb:4IWP|rcsb pdb:4IWQ|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:5EP6|rcsb pdb:5W5V|rcsb pdb:6BNY|rcsb pdb:6BOD|rcsb pdb:6BOE|rcsb pdb:6CQ0|rcsb pdb:6CQ4|rcsb pdb:6CQ5|rcsb pdb:6NT9|rcsb pdb:6O8B|rcsb pdb:6RSR|rcsb pdb:6RST|rcsb pdb:6RSU|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3249367|reactome:R-HSA-3270619|reactome:R-HSA-9008059|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9679191|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|refseq:XP_005268866.1|refseq:XP_005268867.1|dip:DIP-27529N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Cf+RbPJBZTpm7XIqbAD2OEC6VEs9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q15750	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSP00000216160|ensembl:ENST00000331454|ensembl:ENSP00000333049|go:"GO:0003279"(cardiac septum development)|rcsb pdb:7NTI|go:"GO:0003007"(heart morphogenesis)|ensembl:ENSG00000100324(gene)|ensembl:ENST00000216160(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27524N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UMX1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13043	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13188	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:slrC4Ax6263chBC1DJygdoExuCc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y2D8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O60232	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8IY92	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2370740|uniprotkb:Q69YT8|uniprotkb:Q8TF15|uniprotkb:Q96JP1|intact:EBI-2560942|ensembl:ENSP00000294008	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:slx4_human(display_long)|uniprotkb:SLX4(gene name)|psi-mi:SLX4(display_short)|uniprotkb:BTB/POZ domain-containing protein 12(gene name synonym)|uniprotkb:BTBD12(gene name synonym)|uniprotkb:KIAA1784(gene name synonym)|uniprotkb:KIAA1987(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_115820.2|ensembl:ENSG00000188827(gene)|ensembl:ENST00000294008(transcript)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0033557"(Slx1-Slx4 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0090656"(t-circle formation)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904431"(positive regulation of t-circle formation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR018574|rcsb pdb:4M7C|rcsb pdb:4UYI|rcsb pdb:4ZOU|rcsb pdb:7BU5|reactome:R-HSA-5693568|reactome:R-HSA-6783310	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:NuJHCWXHD3dfQNmsNz/LVD0UHsQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O60292	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2559690|uniprotkb:Q2TV87|intact:EBI-28973263|ensembl:ENSP00000222345	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:si1l3_human(display_long)|uniprotkb:SIPA1L3(gene name)|psi-mi:SIPA1L3(display_short)|uniprotkb:KIAA0545(gene name synonym)|uniprotkb:SPAL3(gene name synonym)|uniprotkb:SPA-1-like protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000222345|refseq:XP_011524959.1|refseq:NP_055888.1|ensembl:ENSG00000105738(gene)|ensembl:ENST00000222345(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001725"(stress fiber)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0045177"(apical part of cell)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR031204|interpro:IPR035974|interpro:IPR036034|mint:O60292|go:"GO:0061689"(tricellular tight junction)|refseq:XP_005258728.1|refseq:XP_016882006.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:IzfxQ79AL5Y4lieFeMcvEYmPJu49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9P2F8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2797173|uniprotkb:Q5VXR8|uniprotkb:Q641Q4|uniprotkb:Q5VXR7|uniprotkb:Q9H9F6|uniprotkb:Q96DZ3|uniprotkb:Q8NA38|intact:EBI-2880635|uniprotkb:Q2TV88|ensembl:ENSP00000262861|ensembl:ENSP00000355589|ensembl:ENSP00000502693	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:si1l2_human(display_long)|uniprotkb:KIAA1389(gene name synonym)|uniprotkb:SIPA1L2(gene name)|psi-mi:SIPA1L2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011542545.1|refseq:NP_065859.3|refseq:XP_005273268.1|refseq:XP_005273269.1|refseq:XP_005273270.1|ensembl:ENSG00000116991(gene)|ensembl:ENST00000262861(transcript)|ensembl:ENST00000366630(transcript)|ensembl:ENST00000674635(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR031203|interpro:IPR035974|interpro:IPR036034|refseq:XP_016857385.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:qmmHDrxjsNJ1RR8ixhGC0ohDCFM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H0K1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1181664|uniprotkb:A8K5B8|uniprotkb:O94878|uniprotkb:Q17RV0|uniprotkb:Q6AZE2|uniprotkb:Q76N03|uniprotkb:Q8NCV7|uniprotkb:Q96CZ8|uniprotkb:B0YJ94|ensembl:ENSP00000305976	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sik2_human(display_long)|uniprotkb:SIK2(gene name)|psi-mi:SIK2(display_short)|uniprotkb:Qin-induced kinase(gene name synonym)|uniprotkb:SNF1LK2(gene name synonym)|uniprotkb:KIAA0781(gene name synonym)|uniprotkb:QIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNF1-like kinase 2(gene name synonym)|uniprotkb:Salt-inducible kinase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_056006.1|ensembl:ENSG00000170145(gene)|ensembl:ENST00000304987(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017090(Serine/threonine-protein kinase, SNF1-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:h9FQ/a2qA7FtWC0yWI1pK4LTZtA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q15464	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-4402156|uniprotkb:B9EGM0|uniprotkb:D3DRQ5|uniprotkb:Q504U5|uniprotkb:Q5VUM8|ensembl:ENSP00000366936	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:shb_human(display_long)|uniprotkb:SHB(gene name)|psi-mi:SHB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003019.2|ensembl:ENSG00000107338(gene)|ensembl:ENST00000377707(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR000980(SH2 motif)|interpro:IPR035040|interpro:IPR035045|interpro:IPR036860|mint:Q15464|reactome:R-HSA-4420097	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:DD+KZlDzdHYok9if0pI0b4yKcf49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UBV2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96EE3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-922818|uniprotkb:Q8NFU6|uniprotkb:Q96MH3|uniprotkb:Q9C069|uniprotkb:A8K5B1|ensembl:ENSP00000262124	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:seh1_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:GATOR complex protein SEH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001013455.1|refseq:NP_112493.2|ensembl:ENSP00000262124|ensembl:ENST00000399892|ensembl:ENSP00000382779|ensembl:ENSG00000085415(gene)|ensembl:ENST00000262124(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034629"|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0061700"(GATOR2 complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|mint:Q96EE3|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:I/aUTa3zTawK6QwtkrUkO8B51W49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96T21	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-954116|intact:EBI-28979217|ensembl:ENSP00000364965|uniprotkb:Q9H0A1|uniprotkb:Q8IYC0|uniprotkb:Q5HYY1|uniprotkb:F8W892|uniprotkb:Q7L1Z0	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sebp2_human(display_long)|uniprotkb:SECISBP2(gene name)|psi-mi:SECISBP2(display_short)|uniprotkb:SBP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001269617.1|refseq:NP_001269618.1|ensembl:ENSG00000187742(gene)|ensembl:ENST00000375807(transcript)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0021756"(striatum development)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0048666"(neuron development)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|interpro:IPR040051|mint:Q96T21|reactome:R-HSA-2408557|ensembl:ENST00000339901|ensembl:ENSP00000364959|ensembl:ENSP00000364965|ensembl:ENST00000534113|ensembl:ENSP00000436650|refseq:NP_076982.3|refseq:XP_011517302.1|refseq:XP_006717345.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:KwZEgErldBNsolKlb/EK6OLJCJA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O95487	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q15437	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O15027	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96C92	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-717093|uniprotkb:A6NCP1|uniprotkb:O60525|uniprotkb:Q5SXN1|uniprotkb:Q5SXN2|uniprotkb:Q5SXN3|uniprotkb:Q5SXN4|uniprotkb:Q5SXN8|uniprotkb:Q9NVY5|uniprotkb:Q6V704|ensembl:ENSP00000349929	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:entr1_human(display_long)|uniprotkb:ENTR1(gene name)|psi-mi:ENTR1(display_short)|uniprotkb:Antigen NY-CO-3(gene name synonym)|uniprotkb:SDCCAG3(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001034796.1|refseq:NP_001034797.1|refseq:NP_006634.3|ensembl:ENSG00000165689(gene)|ensembl:ENST00000357365(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005813"(centrosome)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:1903566"(positive regulation of protein localization to cilium)|interpro:IPR026757	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:DSgzbp57wLtRY2EX7zoT5jNuTrI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H4B6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1017775|uniprotkb:Q6IA58|uniprotkb:Q9H949|uniprotkb:Q9HAK9|uniprotkb:A8K4B8|uniprotkb:D3DSB6|ensembl:ENSP00000324729	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sav1_human(display_long)|uniprotkb:SAV1(gene name)|psi-mi:SAV1(display_short)|uniprotkb:WW45(gene name synonym)|uniprotkb:45 kDa WW domain protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_068590.1|ensembl:ENSG00000151748(gene)|ensembl:ENST00000324679(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|mint:Q9H4B6|rcsb pdb:6AO5|reactome:R-HSA-2028269|dip:DIP-36127N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:djvNX49LV19MDK/wNLfLkX2JMxM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6R327	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1387196|uniprotkb:Q68DT5|uniprotkb:Q86UB7|uniprotkb:Q8N3A0|uniprotkb:Q8NCM6|uniprotkb:B2RNX0|uniprotkb:B7ZMF7|ensembl:ENSP00000349959	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rictr_human(display_long)|uniprotkb:RICTOR(gene name)|psi-mi:RICTOR(display_short)|uniprotkb:KIAA1999(gene name synonym)|uniprotkb:AVO3 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001272368.1|refseq:NP_001272369.1|refseq:NP_689969.2|dip:DIP-39479N|ensembl:ENST00000357387(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0043022"(ribosome binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028267|interpro:IPR028268|interpro:IPR029259|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|mint:Q6R327|rcsb pdb:5ZCS|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|reactome:R-HSA-6804757|ensembl:ENSG00000164327(gene)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:LlVf8U/ZLBh0fYyzx8RzSpm+1sc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5T481	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11352885|uniprotkb:B5A868|uniprotkb:A6NIP5|uniprotkb:Q5JVI1|intact:EBI-28967165|ensembl:ENSP00000358532	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rbm20_human(display_long)|uniprotkb:RBM20(gene name)|psi-mi:RBM20(display_short)|uniprotkb:RNA-binding motif protein 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000358532|refseq:NP_001127835.2|ensembl:ENSG00000203867(gene)|ensembl:ENST00000369519(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0007507"(heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034790|interpro:IPR034791|interpro:IPR035979	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:qCYoyiSoR6P8GsoPG7PjoSzjkoo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y4B4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-948156|uniprotkb:Q8TB57|uniprotkb:Q9BV54|intact:EBI-28975962|ensembl:ENSP00000386520|ensembl:ENSP00000507587	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:arip4_human(display_long)|uniprotkb:ARIP4(gene name synonym)|uniprotkb:KIAA0809(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 4(gene name synonym)|uniprotkb:RAD54-like protein 2(gene name synonym)|uniprotkb:RAD54L2(gene name)|psi-mi:RAD54L2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000386520|ensembl:ENSP00000507587|refseq:NP_055921.2|refseq:NP_001309182.1|refseq:NP_001309185.1|ensembl:ENSG00000164080(gene)|ensembl:ENST00000409535(transcript)|ensembl:ENST00000684192(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|interpro:IPR044573|interpro:IPR044574|mint:Q9Y4B4|refseq:XP_006713125.1|refseq:XP_016861476.1|refseq:XP_016861477.1|dip:DIP-47284N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:zqpCSF3VF9OddWH5I84o4fDkoMM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H0H5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-717233|uniprotkb:Q6PJ26|uniprotkb:Q9NWN2|uniprotkb:Q9P250|uniprotkb:Q9P2W2|ensembl:ENSP00000309871|ensembl:ENSP00000404190|ensembl:ENSP00000404808|ensembl:ENSP00000449370|ensembl:ENSP00000449374	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rgap1_human(display_long)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:KIAA1478(gene name synonym)|uniprotkb:MGCRACGAP(gene name synonym)|uniprotkb:Protein CYK4 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_037409.2|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_001306934.1|refseq:NP_001306935.1|refseq:NP_001306936.1|refseq:XP_011536540.1|refseq:XP_006719422.1|refseq:XP_016874709.1|ensembl:ENSG00000161800(gene)|ensembl:ENST00000312377(transcript)|ensembl:ENST00000427314(transcript)|ensembl:ENST00000454520(transcript)|ensembl:ENST00000547905(transcript)|ensembl:ENST00000551016(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q9H0H5|rcsb pdb:2OVJ|rcsb pdb:3W6R|rcsb pdb:3WPQ|rcsb pdb:3WPS|rcsb pdb:4B6D|rcsb pdb:5C2J|rcsb pdb:5C2K|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013423|reactome:R-HSA-983189|dip:DIP-33087N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9BXF6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1387068|uniprotkb:O94939|uniprotkb:Q9P0M1|ensembl:ENSP00000258098	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rfip5_human(display_long)|uniprotkb:RAB11FIP5(gene name)|psi-mi:RAB11FIP5(display_short)|uniprotkb:GAF1(gene name synonym)|uniprotkb:KIAA0857(gene name synonym)|uniprotkb:RIP11(gene name synonym)|uniprotkb:Rab11-interacting protein Rip11(gene name synonym)|uniprotkb:Gamma-SNAP-associated factor 1(gene name synonym)|uniprotkb:Phosphoprotein pp75(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_056285.1|ensembl:ENSG00000135631(gene)|ensembl:ENST00000258098(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030141"(secretory granule)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070164"(negative regulation of adiponectin secretion)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR019018|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q9BXF6|go:"GO:0034451"(centriolar satellite)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:X3eYUlRpL+nSmU4gfUEA5RntseY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q12923	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5JSZ5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q86XN7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-12503142|ensembl:ENSP00000332034|uniprotkb:A6NJ97|uniprotkb:Q6P2S2|uniprotkb:Q7Z3X5|uniprotkb:Q8N3D2|uniprotkb:Q8N3P1|uniprotkb:Q9H9M1	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:prsr1_human(display_long)|uniprotkb:PROSER1(gene name)|psi-mi:PROSER1(display_short)|uniprotkb:C13orf23(gene name synonym)|uniprotkb:KIAA2032(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000332034|ensembl:ENST00000625998|ensembl:ENSP00000486159|ensembl:ENSG00000120685(gene)|ensembl:ENST00000352251(transcript)|interpro:IPR028011|interpro:IPR042616|refseq:NP_079414.3|refseq:XP_005266602.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:XNLnUfD3J/Ic4TTP7Ft8uwbsenw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P62136	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NRX1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-712787|ensembl:ENSP00000263657|uniprotkb:Q53G13|uniprotkb:Q8WVB8|uniprotkb:A8K6Q0	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:pno1_human(display_long)|uniprotkb:Partner of NOB1(gene name synonym)|uniprotkb:PNO1(gene name)|psi-mi:PNO1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000115946(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR004087(K Homology)|interpro:IPR036612|interpro:IPR039912|mint:Q9NRX1|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|reactome:R-HSA-6790901|reactome:R-HSA-6791226|ensembl:ENST00000263657(transcript)|refseq:NP_064528.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:zxUnBMJ/10/uydzhq1t1UaNAwmo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6P1K2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P53350	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O43164	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1996038|uniprotkb:D3DSZ5|uniprotkb:Q68D49|uniprotkb:Q8N1G5|uniprotkb:A8K6U4|ensembl:ENSP00000354775|ensembl:ENSP00000355284	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:pja2_human(display_long)|uniprotkb:PJA2(gene name)|psi-mi:PJA2(display_short)|uniprotkb:KIAA0438(gene name synonym)|uniprotkb:RNF131(gene name synonym)|uniprotkb:RING finger protein 131(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Praja-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_055634.3|refseq:XP_016865588.1|ensembl:ENSG00000198961(gene)|ensembl:ENST00000361189(transcript)|ensembl:ENST00000361557(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007616"(long-term memory)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030639|mint:O43164|reactome:R-HSA-983168|dip:DIP-47040N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:z0OkXLozXymqwyF+xQR+PFa+bQI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q86UU1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-4289858|uniprotkb:Q4KMF8|uniprotkb:Q8TEQ2|uniprotkb:O75133|uniprotkb:B0YJ63|uniprotkb:B0YJ64|intact:EBI-28975144|ensembl:ENSP00000354498|ensembl:ENSP00000469820	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:phlb1_human(display_long)|uniprotkb:PHLDB1(gene name)|psi-mi:PHLDB1(display_short)|uniprotkb:KIAA0638(gene name synonym)|uniprotkb:LL5A(gene name synonym)|uniprotkb:Protein LL5-alpha(gene name synonym)|uniprotkb:DLNB07(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000356063|ensembl:ENSP00000348359|ensembl:ENSP00000354498|ensembl:ENST00000528594|ensembl:ENSP00000435520|ensembl:ENST00000530994|ensembl:ENSP00000431508|ensembl:ENSP00000469820|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810|mint:Q86UU1|ensembl:ENSG00000019144(gene)|ensembl:ENST00000361417(transcript)|ensembl:ENST00000600882(transcript)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0045180"(basal cortex)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_001138230.1|refseq:NP_001138231.1|refseq:NP_055972.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Za4UuXVuMr4gzY2kr8EadOf5hWA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H792	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2609701|uniprotkb:Q6ZS78|uniprotkb:Q8TEG7|uniprotkb:Q8NCM3|uniprotkb:Q8NAZ4|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:peak1_human(display_long)|uniprotkb:PEAK1(gene name)|psi-mi:PEAK1(display_short)|uniprotkb:KIAA2002(gene name synonym)|uniprotkb:Sugen kinase 269(gene name synonym)|uniprotkb:Tyrosine-protein kinase SgK269(gene name synonym)|uniprotkb:Pseudopodium-enriched atypical kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011520335.1|refseq:XP_011520336.1|refseq:XP_011520337.1|refseq:XP_011520338.1|refseq:XP_011520339.1|refseq:XP_011520341.1|refseq:XP_011520340.1|refseq:NP_079052.2|refseq:XP_005254727.1|refseq:XP_005254728.1|refseq:XP_005254730.1|refseq:XP_005254731.1|refseq:XP_005254732.1|ensembl:ENSG00000173517(gene)|ensembl:ENST00000312493(transcript)|ensembl:ENST00000560626(transcript)|ensembl:ENST00000682557(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:6BHC|reactome:R-HSA-9013420|reactome:R-HSA-9013424|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603|dip:DIP-56276N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:z2Q9mOQSYpc1fQJHovBCFsctX749606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UPQ7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11329693|uniprotkb:A7MCZ6|uniprotkb:Q9NSQ2|uniprotkb:Q96CC2|uniprotkb:Q8N2N7|ensembl:ENSP00000263666	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:pzrn3_human(display_long)|uniprotkb:PDZRN3(gene name)|psi-mi:PDZRN3(display_short)|uniprotkb:KIAA1095(gene name synonym)|uniprotkb:LNX3(gene name synonym)|uniprotkb:Ligand of Numb protein X 3(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 3(gene name synonym)|uniprotkb:SEMCAP3(gene name synonym)|uniprotkb:Semaphorin cytoplasmic domain-associated protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PDZRN3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001290068.1|refseq:NP_001290069.1|refseq:NP_001290070.1|refseq:NP_001290071.1|refseq:NP_055824.1|ensembl:ENSG00000121440(gene)|ensembl:ENST00000263666(transcript)|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0004842"(ubiquitin-protein transferase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0005737"(cytoplasm)|go:"GO:0007528"(neuromuscular junction development)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1UHP|go:"GO:0016567"(protein ubiquitination)|rcsb pdb:1WH1|go:"GO:0031594"(neuromuscular junction)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001293(Zinc finger, TRAF-type)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:H3OCIenpzp2anvt0YxQB3/JOLOg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5EBL8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q86TB9	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2562092|uniprotkb:Q8N9M6|uniprotkb:Q2TA86|uniprotkb:Q8NI63|uniprotkb:Q6P166|intact:EBI-2824962|uniprotkb:B3KXT9|ensembl:ENSP00000300146	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:patl1_human(display_long)|uniprotkb:PATL1(gene name)|psi-mi:PATL1(display_short)|uniprotkb:PAT1-like protein 1(gene name synonym)|uniprotkb:OK/KNS-cl.5(orf name)|uniprotkb:Protein PAT1 homolog b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_689929.2|ensembl:ENSG00000166889(gene)|ensembl:ENST00000300146(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0033962"(P-body assembly)|go:"GO:0034046"("poly(G) binding")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:2XEQ|rcsb pdb:2XER|rcsb pdb:2XES|reactome:R-HSA-430039	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:zSppgni6nHKLE+wKkvoXmECuXB09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UKK3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:"Vault poly(ADP-ribose) polymerase"(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699(gene)|ensembl:ENST00000381989(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042493"|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9BZF3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2372709|uniprotkb:B4DTW1|uniprotkb:Q4ZG68|uniprotkb:Q53T68|uniprotkb:Q59H61|uniprotkb:Q7Z4Q1|uniprotkb:Q8N9T0|uniprotkb:Q96SR1|uniprotkb:C4AME4|uniprotkb:C4AMC0|uniprotkb:D3DPF6|uniprotkb:D3DPF7|uniprotkb:Q86V84|intact:EBI-28980578|ensembl:ENSP00000190611	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:osbl6_human(display_long)|uniprotkb:OSBPL6(gene name)|psi-mi:OSBPL6(display_short)|uniprotkb:ORP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001188409.1|refseq:NP_001188410.1|refseq:NP_001188411.1|refseq:NP_115912.1|refseq:NP_665682.1|ensembl:ENSP00000190611|ensembl:ENST00000315022|ensembl:ENSP00000318723|ensembl:ENST00000357080|ensembl:ENSP00000349591|ensembl:ENST00000359685|ensembl:ENSP00000352713|ensembl:ENST00000392505|ensembl:ENSP00000376293|ensembl:ENST00000409045|ensembl:ENSP00000387248|ensembl:ENST00000409631|ensembl:ENSP00000386885|refseq:XP_016858755.1|refseq:XP_016858756.1|refseq:XP_016858759.1|refseq:XP_016858760.1|ensembl:ENSG00000079156(gene)|ensembl:ENST00000190611(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|mint:Q9BZF3|reactome:R-HSA-192105	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:fOUP23b3kO1lBSBPNHP6Ghe6i8c9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13438	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9BZD4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q02818	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P08235	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-3915028|uniprotkb:B0ZBF5|uniprotkb:Q2NKL1|uniprotkb:Q96KQ8|uniprotkb:Q96KQ9|uniprotkb:B0ZBF7|intact:EBI-28983727|ensembl:ENSP00000341390|ensembl:ENSP00000350815	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mcr_human(display_long)|uniprotkb:NR3C2(gene name)|psi-mi:NR3C2(display_short)|uniprotkb:MCR(gene name synonym)|uniprotkb:MLR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011530277.1|refseq:XP_011530278.1|refseq:XP_011530279.1|refseq:NP_000892.2|ensembl:ENST00000342437|ensembl:ENSP00000343907|ensembl:ENSP00000341390|ensembl:ENSP00000350815|ensembl:ENST00000511528|ensembl:ENSP00000421481|ensembl:ENST00000512865|ensembl:ENSP00000423510|ensembl:ENST00000625323|ensembl:ENSP00000486719|refseq:NP_001159576.1|refseq:XP_016863706.1|ensembl:ENSG00000151623(gene)|ensembl:ENST00000344721(transcript)|ensembl:ENST00000358102(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1Y9R|rcsb pdb:1YA3|rcsb pdb:2A3I|rcsb pdb:2AA2|rcsb pdb:2AA5|rcsb pdb:2AA6|rcsb pdb:2AA7|rcsb pdb:2AAX|rcsb pdb:2AB2|rcsb pdb:2ABI|rcsb pdb:3VHV|rcsb pdb:3WFF|rcsb pdb:3WFG|rcsb pdb:4PF3|rcsb pdb:4TNT|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:5HCV|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:6GGG|rcsb pdb:6L88|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|rcsb pdb:2OAX|rcsb pdb:3VHU	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:R2pcuhQngTwxcmSKS5jrczOxBIk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q12968	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-5278441|uniprotkb:O75211|uniprotkb:Q14516|uniprotkb:Q99840|uniprotkb:Q99841|uniprotkb:Q99842|ensembl:ENSP00000300659	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:nfac3_human(display_long)|uniprotkb:NFATC3(gene name)|psi-mi:NFATC3(display_short)|uniprotkb:NFAT4(gene name synonym)|uniprotkb:NFATx(gene name synonym)|uniprotkb:T-cell transcription factor NFAT4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_004546.1|refseq:NP_775186.1|refseq:NP_775188.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902894"(negative regulation of miRNA transcription)|ensembl:ENSG00000072736(gene)|ensembl:ENST00000346183(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|interpro:IPR037059|rcsb pdb:2XRW|rcsb pdb:2XS0|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-5607763	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:YhaCvxbZKhSOtPQqf5dj5XVr8X89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O95644	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-6907210|uniprotkb:Q12865|uniprotkb:Q15793|uniprotkb:B5B2M4|uniprotkb:B5B2M5|uniprotkb:B5B2M6|uniprotkb:B5B2M7|uniprotkb:B5B2M8|uniprotkb:B5B2M9|uniprotkb:B5B2N1|uniprotkb:Q2M1S3|ensembl:ENSP00000389377	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:nfac1_human(display_long)|uniprotkb:NFATC1(gene name)|psi-mi:NFATC1(display_short)|uniprotkb:NFAT2(gene name synonym)|uniprotkb:NFATC(gene name synonym)|uniprotkb:NFAT transcription complex cytosolic component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006153.2|refseq:NP_765975.1|refseq:NP_765976.1|refseq:NP_765977.1|refseq:NP_765978.1|refseq:NP_001265598.1|refseq:NP_001265599.1|refseq:NP_001265601.1|refseq:NP_001265602.1|refseq:NP_001265604.1|dip:DIP-44311N|ensembl:ENSG00000131196(gene)|ensembl:ENST00000427363(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015647(Nuclear factor of activated T-cells 1)|interpro:IPR032397|interpro:IPR037059|mint:O95644|rcsb pdb:1A66|rcsb pdb:1NFA|rcsb pdb:5SVE|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ighU5P59Gv8yTk6lwwm/Ohy3FdY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NXR1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-941227|uniprotkb:Q49AQ2|ensembl:ENSP00000379642|ensembl:ENSP00000379643|ensembl:ENSP00000488050|ensembl:ENSP00000488199|ensembl:ENSP00000501936|ensembl:ENSP00000502160|ensembl:ENSP00000502354|ensembl:ENSP00000502635	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:nde1_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short)|uniprotkb:NUDE(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001137451.1|refseq:NP_060138.1|refseq:XP_016878838.1|refseq:XP_016878845.1|ensembl:ENSG00000072864(gene)|ensembl:ENSG00000275911(gene)|ensembl:ENST00000396354(transcript)|ensembl:ENST00000396355(transcript)|ensembl:ENST00000631844(transcript)|ensembl:ENST00000631923(transcript)|ensembl:ENST00000674554(transcript)|ensembl:ENST00000674888(transcript)|ensembl:ENST00000675926(transcript)|ensembl:ENST00000675951(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9NXR1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:H769EmQerGWsy6Zud3BBzkAuQw49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O14777	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y618	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-80830|uniprotkb:Q9Y5U0|uniprotkb:O00613|uniprotkb:O15416|uniprotkb:Q13354|uniprotkb:O15421|intact:EBI-28976851|uniprotkb:Q56D06|uniprotkb:Q59GM0|ensembl:ENSP00000384018	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ncor2_human(display_long)|uniprotkb:NCOR2(gene name)|psi-mi:NCOR2(display_short)|uniprotkb:CTG26(gene name synonym)|uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)|uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym)|uniprotkb:T3 receptor-associating factor(gene name synonym)|uniprotkb:CTG repeat protein 26(gene name synonym)|uniprotkb:SMAP270(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000384018|refseq:NP_001070729.2|refseq:NP_001193583.1|refseq:NP_006303.4|dip:DIP-951N|ensembl:ENSG00000196498(gene)|ensembl:ENST00000405201(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007595"(lactation)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:Q9Y618|rcsb pdb:1KKQ|rcsb pdb:1R2B|rcsb pdb:1XC5|rcsb pdb:2GPV|rcsb pdb:2L5G|rcsb pdb:2LTP|rcsb pdb:2ODD|rcsb pdb:2RT5|rcsb pdb:3R29|rcsb pdb:3R2A|rcsb pdb:4A69|rcsb pdb:4OAR|rcsb pdb:5X8Q|rcsb pdb:5X8X|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6A22|rcsb pdb:6IVX|rcsb pdb:6PDZ|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:58SZfHIXN3dZN93fsiVHbbEwD0g9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O75376	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q15596	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-81236|uniprotkb:Q14CD2|ensembl:ENSP00000399968	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ncoa2_human(display_long)|uniprotkb:NCOA2(gene name)|psi-mi:NCOA2(display_short)|uniprotkb:TIF2(gene name synonym)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:BHLHE75(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 75(gene name synonym)|uniprotkb:SRC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_006531.1|rcsb pdb:1ZDU|rcsb pdb:1ZKY|rcsb pdb:2AO6|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2LDC|rcsb pdb:2P15|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2Q7J|rcsb pdb:2Q7L|rcsb pdb:2YJD|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3A9E|rcsb pdb:3CLD|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E7C|rcsb pdb:3E94|rcsb pdb:3ERD|rcsb pdb:3FUG|rcsb pdb:3GN8|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:3KWY|rcsb pdb:3KYT|rcsb pdb:3L0E|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:3O1D|rcsb pdb:3O1E|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3PLZ|rcsb pdb:3Q95|rcsb pdb:3R5M|rcsb pdb:3UP0|rcsb pdb:3UP3|rcsb pdb:4CSJ|rcsb pdb:4DOS|rcsb pdb:4E2J|rcsb pdb:4FHH|rcsb pdb:4FHI|rcsb pdb:4IA1|rcsb pdb:4IA2|rcsb pdb:4IA3|rcsb pdb:4IA7|rcsb pdb:4IQR|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|ensembl:ENSG00000140396(gene)|ensembl:ENST00000452400(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15596|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1M2Z|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1P93|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1UHL|rcsb pdb:1YOK|rcsb pdb:1ZDT|rcsb pdb:4Q0A|rcsb pdb:4Q13|rcsb pdb:4QE6|rcsb pdb:4QE8|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4PXM|rcsb pdb:4RME|rcsb pdb:4RUO|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:4WG0|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4NIE|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4IU7|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EC9|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5G3J|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5U2D|rcsb pdb:5UAN|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5G46|rcsb pdb:5G5W|rcsb pdb:5H1E|rcsb pdb:5HYR|rcsb pdb:5I4V|rcsb pdb:5IAW|rcsb pdb:5ICK|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5L11|rcsb pdb:5LGA|rcsb pdb:5LYQ|rcsb pdb:5MK4|rcsb pdb:5G45|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5Q17|rcsb pdb:5SYZ|rcsb pdb:5T1Z|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:6KNU|rcsb pdb:6KNV|rcsb pdb:6KNW|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6LIT|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6VC2|rcsb pdb:6VIF|rcsb pdb:7A77|rcsb pdb:7A78|rcsb pdb:7A79|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7D42|rcsb pdb:6KKE|rcsb pdb:7JHD|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5625886|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-193807|rcsb pdb:5VQL|rcsb pdb:5WGQ|rcsb pdb:5WZX|rcsb pdb:5XPL|rcsb pdb:5Y1J|rcsb pdb:5Y49|rcsb pdb:5YP5|rcsb pdb:5YXB|rcsb pdb:5YXD|rcsb pdb:5YXJ|rcsb pdb:5YXL|rcsb pdb:5Z12|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:5VQK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6ESN|rcsb pdb:6KKB|refseq:NP_001308642.1|refseq:NP_001308632.1|refseq:NP_001308636.1|refseq:NP_001308640.1|refseq:NP_001308641.1|dip:DIP-5997N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:dZP564B7sZPW/ro5h2CVE2XJJpk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q92802	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068|ensembl:ENSP00000501416|ensembl:ENSP00000501516|ensembl:ENSP00000501518|ensembl:ENSP00000501537	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754(gene)|ensembl:ENST00000267068(transcript)|ensembl:ENST00000674349(transcript)|ensembl:ENST00000674421(transcript)|ensembl:ENST00000674465(transcript)|ensembl:ENST00000674484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001824"(blastocyst development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR026568|interpro:IPR027417|mint:Q92802	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O75592-2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-12503140	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:o75592-2(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	intact:EBI-1043774(isoform-parent)|uniprotkb:O75592-2(isoform-parent)	-	-	isoform-comment:Derived from EST data.	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:3Rs3RMw3itW8YGy7jvcT3tDSXEU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13615	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8NCE2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-5658424|uniprotkb:Q86VK9|uniprotkb:Q6PIZ4|uniprotkb:Q8IYK1|uniprotkb:Q0JU83|uniprotkb:Q9H6C0|uniprotkb:Q6QE21|uniprotkb:Q0JTH5|uniprotkb:Q8TCM7|ensembl:ENSP00000296003	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mtmre_human(display_long)|uniprotkb:C3orf29(gene name synonym)|uniprotkb:HCV NS5A-transactivated protein 4 splice variant A-binding protein 1(gene name synonym)|uniprotkb:hJumpy(gene name synonym)|uniprotkb:MTMR14(gene name)|psi-mi:MTMR14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001070993.1|refseq:NP_001070994.1|refseq:NP_071930.2|ensembl:ENSG00000163719(gene)|ensembl:ENST00000296003(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016236"(macroautophagy)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR039802|interpro:IPR039803|mint:Q8NCE2|reactome:R-HSA-1632852|reactome:R-HSA-1660499	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ftagAuEsNaEzJHotTrA3OjWPPN09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NYP9	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1104552|uniprotkb:Q542Z0|ensembl:ENSP00000290130|uniprotkb:B2R562	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ms18a_human(display_long)|uniprotkb:MIS18A(gene name)|psi-mi:MIS18A(display_short)|uniprotkb:FAPP1-associated protein 1(gene name synonym)|uniprotkb:C21orf46(gene name synonym)|uniprotkb:FASP1(gene name synonym)|uniprotkb:C21orf45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_061817.1|ensembl:ENST00000290130(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034752|reactome:R-HSA-606279|ensembl:ENSG00000159055(gene)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:dzfhVJeuppOL/OASRY71tyXTAn49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NXC5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2515122|ensembl:ENSP00000339881|ensembl:ENSP00000384088|uniprotkb:Q7L551|uniprotkb:Q9H092|uniprotkb:O75216|uniprotkb:B2RTV6	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mio_human(display_long)|uniprotkb:MIOS(gene name)|psi-mi:MIOS(display_short)|uniprotkb:Missing oocyte meiosis regulator homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000164654(gene)|ensembl:ENST00000340080(transcript)|ensembl:ENST00000405785(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034629"|go:"GO:0061700"(GATOR2 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031488|interpro:IPR036322|interpro:IPR037593|reactome:R-HSA-9639288|go:"GO:0005737"(cytoplasm)|refseq:NP_061878.3|refseq:XP_005249837.1|refseq:XP_005249838.1|refseq:XP_005249839.1|refseq:XP_016867850.1|dip:DIP-53801N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:d4qQXzBhVy/sB26TikIOei6QkwM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96GX5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2556114|uniprotkb:Q5T8D5|uniprotkb:Q5T8D7|uniprotkb:Q96SJ5|uniprotkb:Q8NCD6|ensembl:ENSP00000365107	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gwl_human(display_long)|uniprotkb:GW(gene name synonym)|uniprotkb:GWL(gene name synonym)|uniprotkb:THC2(gene name synonym)|uniprotkb:MASTL(gene name)|psi-mi:MASTL(display_short)|uniprotkb:Microtubule-associated serine/threonine-protein kinase-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001165774.1|refseq:NP_001165775.1|refseq:NP_116233.2|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000120539(gene)|ensembl:ENST00000375940(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR037638|rcsb pdb:5LOH|reactome:R-HSA-2465910|interpro:IPR000961(Protein kinase, C-terminal)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:+KiVOlyI1QBhdDo8TjgbqpYr/cE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9BPZ7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-749938|uniprotkb:Q00426|intact:EBI-1237531|uniprotkb:A8K1Z5|uniprotkb:B1AMA4|uniprotkb:Q5JSV5|uniprotkb:Q5JSV6|uniprotkb:Q5JSV9|uniprotkb:Q658R0|uniprotkb:Q699U1|uniprotkb:Q699U2|uniprotkb:Q699U3|uniprotkb:Q699U4|uniprotkb:Q6GVJ0|uniprotkb:Q6GVJ1|uniprotkb:Q6GVJ2|intact:EBI-1048293|uniprotkb:B7Z309|ensembl:ENSP00000265960|ensembl:ENSP00000362597	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sin1_human(display_long)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2-associated protein 1(gene name synonym)|uniprotkb:Stress-activated map kinase-interacting protein 1(gene name synonym)|uniprotkb:MAPKAP1(gene name)|psi-mi:MAPKAP1(display_short)|uniprotkb:SIN1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001006618.1|refseq:NP_001006619.1|refseq:NP_001006620.1|refseq:NP_001006621.1|refseq:NP_001006622.1|refseq:NP_077022.1|refseq:XP_011517312.1|refseq:XP_016870615.1|dip:DIP-39480N|ensembl:ENSG00000119487(gene)|ensembl:ENST00000265960(transcript)|ensembl:ENST00000373498(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031932"(TORC2 complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|interpro:IPR008828(Stress-activated map kinase interacting 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031313|interpro:IPR031567|interpro:IPR032679|mint:Q9BPZ7|rcsb pdb:3VOQ|rcsb pdb:5ZCS|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|reactome:R-HSA-6804757|refseq:XP_016870616.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:kIAa8HfqaJhvssnCDV2/8fj3JYA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q99683	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-476263|uniprotkb:Q5THN3|uniprotkb:Q99461|uniprotkb:A6NIA0|uniprotkb:B4DGB2|ensembl:ENSP00000351908	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:m3k5_human(display_long)|uniprotkb:MAPK/ERK kinase kinase 5(gene name synonym)|uniprotkb:Apoptosis signal-regulating kinase 1(gene name synonym)|uniprotkb:MAP3K5(gene name)|psi-mi:MAP3K5(display_short)|uniprotkb:ASK1(gene name synonym)|uniprotkb:MAPKKK5(gene name synonym)|uniprotkb:MEKK5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005914.1|dip:DIP-29516N|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|ensembl:ENSG00000197442(gene)|ensembl:ENST00000359015(transcript)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072577"(endothelial cell apoptotic process)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025136|interpro:IPR043969|mint:Q99683|rcsb pdb:2CLQ|rcsb pdb:3VW6|rcsb pdb:4BF2|rcsb pdb:4BHN|rcsb pdb:4BIB|rcsb pdb:4BIC|rcsb pdb:4BID|rcsb pdb:4BIE|rcsb pdb:5ULM|rcsb pdb:5UOR|rcsb pdb:5UOX|rcsb pdb:5UP3|rcsb pdb:5V19|rcsb pdb:5V24|rcsb pdb:5VIL|rcsb pdb:5VIO|rcsb pdb:6E2M|rcsb pdb:6E2N|rcsb pdb:6E2O|rcsb pdb:6EJL|rcsb pdb:6OYT|rcsb pdb:6OYW|rcsb pdb:6VRE|rcsb pdb:6XIH|reactome:R-HSA-2559580	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:/txMHg7GSCpK8ij48YDHGARX3es9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q92585	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-908250|uniprotkb:Q9NZ12|intact:EBI-28987697|ensembl:ENSP00000292599|ensembl:ENSP00000491444	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:maml1_human(display_long)|uniprotkb:MAML1(gene name)|psi-mi:MAML1(display_short)|uniprotkb:KIAA0200(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_055572.1|ensembl:ENSP00000292599|ensembl:ENSP00000491444|dip:DIP-29920N|ensembl:ENSG00000161021(gene)|ensembl:ENSG00000283780(gene)|ensembl:ENST00000292599(transcript)|ensembl:ENST00000638220(transcript)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060928"(atrioventricular node cell development)|interpro:IPR019082|rcsb pdb:2F8X|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:6SMV|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:UvjJk5aUOpC11E8OHyShgJ/dszw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96II8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5VUJ6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2659666|uniprotkb:Q9P233|uniprotkb:Q9HA88|uniprotkb:F5H2T1|uniprotkb:Q08AD5|ensembl:ENSP00000325091	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:lrch2_human(display_long)|uniprotkb:KIAA1495(gene name synonym)|uniprotkb:LRCH2(gene name)|psi-mi:LRCH2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_065922.3|refseq:NP_001230892.1|ensembl:ENSG00000130224(gene)|ensembl:ENST00000317135(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:hjJwBxAeVmoDWTtcKK5NzCIDnBo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y2L9	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2797324|uniprotkb:Q7Z5F7|uniprotkb:Q7Z5F6|uniprotkb:Q5TBU9|uniprotkb:Q2KHR1|uniprotkb:B7ZLL5|uniprotkb:F8W6F0|uniprotkb:Q17R43|ensembl:ENSP00000374448	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:lrch1_human(display_long)|uniprotkb:CHDC1(gene name synonym)|uniprotkb:KIAA1016(gene name synonym)|uniprotkb:Calponin homology domain-containing protein 1(gene name synonym)|uniprotkb:Neuronal protein 81(gene name synonym)|uniprotkb:LRCH1(gene name)|psi-mi:LRCH1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001157685.1|refseq:NP_055931.1|refseq:NP_001157683.1|ensembl:ENSG00000136141(gene)|ensembl:ENST00000389798(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:3oNqV4dI/4ZHz1sUSsc8nmg0j049606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UGP4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2652871|uniprotkb:Q17RQ1|uniprotkb:Q9BQQ9|uniprotkb:Q9NQ47|ensembl:ENSP00000273317	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:limd1_human(display_long)|uniprotkb:LIMD1(gene name)|psi-mi:LIMD1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_055055.1|ensembl:ENSG00000144791(gene)|ensembl:ENST00000273317(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016310"(phosphorylation)|go:"GO:0016442"(RISC complex)|go:"GO:0016477"(cell migration)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028734|reactome:R-HSA-1234176	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Eq6aJ83PR4G/LIlUi5H2Bv31sTQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q2M1P5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2512228|ensembl:ENSP00000377934|uniprotkb:Q3SXY0|uniprotkb:Q6UXE9|uniprotkb:Q8IW72	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:kif7_human(display_long)|uniprotkb:KIF7(gene name)|psi-mi:KIF7(display_short)|uniprotkb:UNQ340/PRO539(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000166813(gene)|ensembl:ENST00000394412(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q2M1P5|rcsb pdb:2XT3|rcsb pdb:4A14|rcsb pdb:6MLQ|rcsb pdb:6MLR|reactome:R-HSA-5610787|reactome:R-HSA-5632684|refseq:NP_940927.2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:yEZWFId7u3KkCdclCbZNeAZS1B49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9C0D2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1104837|uniprotkb:Q8N7L4|uniprotkb:Q8N919|uniprotkb:Q8N9B0|uniprotkb:Q96LT8|uniprotkb:C9J5H9|uniprotkb:C9JQY8|ensembl:ENSP00000316681	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ce295_human(display_long)|uniprotkb:CEP295(gene name)|psi-mi:CEP295(display_short)|uniprotkb:KIAA1731(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_203753.1|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR029299|interpro:IPR029560|ensembl:ENSG00000166004(gene)|ensembl:ENST00000325212(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:hhqEkBkuZNzJcjRlLHfRfZ8tE6Q9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9P266	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-6874715|ensembl:ENSP00000364526|uniprotkb:Q5HYA7|uniprotkb:Q5T992|uniprotkb:Q86WZ9|uniprotkb:Q9BYJ2	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:jcad_human(display_long)|uniprotkb:JCAD(gene name)|psi-mi:JCAD(display_short)|uniprotkb:KIAA1462(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000364526|refseq:XP_011517910.1|ensembl:ENSG00000165757(gene)|ensembl:ENST00000375377(transcript)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR028221|refseq:NP_065899.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:OvmF2tJEt3Vy2Za67BHf6cRHDX89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O94964	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2433678|uniprotkb:A6NK10|uniprotkb:Q14DB2|uniprotkb:Q5JW51|uniprotkb:Q6ZTG8	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:soga1_human(display_long)|uniprotkb:SOGA1(gene name)|psi-mi:SOGA1(display_short)|uniprotkb:C20orf117(gene name synonym)|uniprotkb:KIAA0889(gene name synonym)|uniprotkb:SOGA(gene name synonym)|uniprotkb:SOGA family member 1(gene name synonym)|uniprotkb:Suppressor of glucose by autophagy(gene name synonym)|uniprotkb:Suppressor of glucose, autophagy-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_542194.2|refseq:NP_954650.2|interpro:IPR027881|interpro:IPR027882|mint:O94964|go:"GO:0005615"(extracellular space)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0070062"(extracellular exosome)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:m+lk89tvKyS8v/BItPtLX+XUMVU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y597	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-373299|uniprotkb:A0AV15|uniprotkb:Q49AG7|uniprotkb:Q504Q9|uniprotkb:Q6PJN6|uniprotkb:Q8ND58|uniprotkb:Q8NDJ0|uniprotkb:Q8WX16|uniprotkb:D3DTA6|ensembl:ENSP00000259154	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:kctd3_human(display_long)|uniprotkb:KCTD3(gene name)|psi-mi:KCTD3(display_short)|uniprotkb:Renal carcinoma antigen NY-REN-45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_057205.2|refseq:NP_001306223.1|refseq:NP_001306224.1|ensembl:ENST00000259154(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-HSA-9013148|ensembl:ENSG00000136636(gene)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:rd5uwUaxsHyv815HcLJmrI3sgNQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P05412	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y4H2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1049582|uniprotkb:Q96RR2|uniprotkb:Q9BZG0|uniprotkb:Q9Y6I5|ensembl:ENSP00000365016	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:irs2_human(display_long)|uniprotkb:IRS2(gene name)|psi-mi:IRS2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003740.2|ensembl:ENSG00000185950(gene)|ensembl:ENST00000375856(transcript)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009749"(response to glucose)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:Q9Y4H2|rcsb pdb:3FQW|rcsb pdb:3FQX|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-112412|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-2219530|reactome:R-HSA-2428928|reactome:R-HSA-2586552|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-8853659|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-982772|ensembl:ENSP00000365016	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:NziszVpTmWOI7OtDgOZZ9qa69wc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P35568	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-517592|intact:EBI-28983786|ensembl:ENSP00000304895	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:irs1_human(display_long)|uniprotkb:IRS1(gene name)|psi-mi:IRS1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005535.1|ensembl:ENSP00000304895|dip:DIP-523N|ensembl:ENSG00000169047(gene)|ensembl:ENST00000305123(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:P35568|rcsb pdb:1IRS|rcsb pdb:1K3A|rcsb pdb:1QQG|rcsb pdb:2Z8C|rcsb pdb:5U1M|rcsb pdb:6BNT|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-112412|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-2219530|reactome:R-HSA-2428928|reactome:R-HSA-2586552|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-9603381|reactome:R-HSA-982772	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:n/9Epczwu5jOLSKCKhmIgR7CdOw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9C086	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-715611|ensembl:ENSP00000233331	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q0D2I5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-742894|uniprotkb:Q7L5J9|uniprotkb:Q7Z5X4|uniprotkb:Q9BQ46|uniprotkb:Q24JT6|ensembl:ENSP00000380052	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:iffo1_human(display_long)|uniprotkb:IFFO(gene name synonym)|uniprotkb:Tumor antigen HOM-TES-103(gene name synonym)|uniprotkb:IFFO1(gene name)|psi-mi:IFFO1(display_short)|uniprotkb:Intermediate filament family orphan 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001034759.1|refseq:NP_542768.2|ensembl:ENST00000336604|ensembl:ENSP00000337593|ensembl:ENST00000356896|ensembl:ENSP00000349364|ensembl:ENSP00000380052|ensembl:ENST00000487279|ensembl:ENSP00000432493|refseq:XP_006719038.1|refseq:NP_001317253.1|ensembl:ENSG00000010295(gene)|ensembl:ENST00000396840(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035861"(site of double-strand break)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|interpro:IPR039008|rcsb pdb:6ABO	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:KPIbJ3l4gUiKMga1pZywdi3OPbo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O94927	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2558224|uniprotkb:B2RXK1|uniprotkb:Q6P2P7|uniprotkb:Q96CT8|uniprotkb:Q7L3D5|ensembl:ENSP00000439056	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:haus5_human(display_long)|uniprotkb:HAUS5(gene name)|psi-mi:HAUS5(display_short)|uniprotkb:KIAA0841(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_056117.1|ensembl:ENSG00000249115(gene)|ensembl:ENST00000203166(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026215|interpro:IPR029131|mint:O94927|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-48831N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ChAZl+X89FxK08LHh2+lYDqQZn09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q68CZ6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P49841	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-373586|uniprotkb:Q9BWH3|uniprotkb:Q9UL47|uniprotkb:D3DN89|ensembl:ENSP00000264235	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gsk3b_human(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001139628.1|refseq:NP_002084.2|ensembl:ENSG00000082701(gene)|ensembl:ENST00000264235(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006983"(ER overload response)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|rcsb pdb:2JDO|rcsb pdb:2JDR|rcsb pdb:2JLD|rcsb pdb:2O5K|rcsb pdb:2OW3|rcsb pdb:2UW9|rcsb pdb:2X39|rcsb pdb:2XH5|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3DU8|rcsb pdb:3E87|rcsb pdb:3E88|rcsb pdb:3E8D|rcsb pdb:3F7Z|rcsb pdb:3F88|rcsb pdb:3GB2|rcsb pdb:3I4B|rcsb pdb:3L1S|rcsb pdb:3M1S|rcsb pdb:3MV5|rcsb pdb:3OW4|rcsb pdb:3PUP|rcsb pdb:3Q3B|rcsb pdb:3QKK|rcsb pdb:3SAY|rcsb pdb:3SD0|rcsb pdb:3ZDI|rcsb pdb:3ZRK|rcsb pdb:3ZRL|rcsb pdb:3ZRM|rcsb pdb:4ACC|rcsb pdb:4ACD|rcsb pdb:4ACG|rcsb pdb:4ACH|rcsb pdb:4AFJ|rcsb pdb:4B7T|rcsb pdb:4DIT|rcsb pdb:4EKK|rcsb pdb:4IQ6|rcsb pdb:4J1R|rcsb pdb:4PTE|rcsb pdb:4PTG|rcsb pdb:5F94|rcsb pdb:5F95|rcsb pdb:5HLN|rcsb pdb:5HLP|rcsb pdb:5K5N|rcsb pdb:5KPK|rcsb pdb:5KPL|rcsb pdb:5KPM|rcsb pdb:5OY4|rcsb pdb:5T31|rcsb pdb:6B8J|rcsb pdb:6BUU|rcsb pdb:6GJO|rcsb pdb:6GN1|rcsb pdb:6H0U|rcsb pdb:6HK3|rcsb pdb:6HK4|rcsb pdb:6HK7|rcsb pdb:6NPZ|rcsb pdb:6TCU|rcsb pdb:6V6L|rcsb pdb:6Y9R|rcsb pdb:6Y9S|rcsb pdb:7B6F|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198323|reactome:R-HSA-3371453|reactome:R-HSA-399956|reactome:R-HSA-4641262|reactome:R-HSA-5250924|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5674400|reactome:R-HSA-75815|reactome:R-HSA-8939902|rcsb pdb:4J71|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4PTC|reactome:R-HSA-9682706|reactome:R-HSA-9683610|reactome:R-HSA-9694631|reactome:R-HSA-9694686|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019082"(viral protein processing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034452"(dynactin binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048156"(tau protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106027"(neuron projection organization)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:P49841|rcsb pdb:1GNG|rcsb pdb:1H8F|rcsb pdb:1I09|rcsb pdb:1J1B|rcsb pdb:1J1C|rcsb pdb:1O6K|rcsb pdb:1O6L|rcsb pdb:1O9U|rcsb pdb:1PYX|rcsb pdb:1Q3D|rcsb pdb:1Q3W|rcsb pdb:1Q41|rcsb pdb:1Q4L|rcsb pdb:1Q5K|rcsb pdb:1R0E|rcsb pdb:1UV5|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-878N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:dhXyRv7fPByw6we1Rbmh8pYS05o9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NW75	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-5235805|uniprotkb:Q5VYK7|uniprotkb:Q5VYK8|uniprotkb:Q86YE7|ensembl:ENSP00000355902	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gptc2_human(display_long)|uniprotkb:GPATCH2(gene name)|psi-mi:GPATCH2(display_short)|uniprotkb:GPATC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001284683.1|refseq:NP_060510.1|ensembl:ENSG00000092978(gene)|ensembl:ENST00000366935(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR000467(D111/G-patch)|interpro:IPR026291	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:xN+DJXEFfJDSohngjxM0++LBeP49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P10071	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P10070	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-10821567|intact:EBI-28969755|ensembl:ENSP00000390436|uniprotkb:O60252|uniprotkb:O60253|uniprotkb:O60254|uniprotkb:O60255|uniprotkb:Q15590|uniprotkb:Q15591|uniprotkb:Q4JHT4	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gli2_human(display_long)|uniprotkb:GLI2(gene name)|psi-mi:GLI2(display_short)|uniprotkb:THP(gene name synonym)|uniprotkb:GLI family zinc finger protein 2(gene name synonym)|uniprotkb:Tax helper protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000390436|ensembl:ENSG00000074047(gene)|ensembl:ENST00000452319(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0021508"(floor plate formation)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030879"(mammary gland development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031514"(motile cilium)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0035295"(tube development)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048666"(neuron development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060032"(notochord regression)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0098586"(cellular response to virus)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|reactome:R-HSA-5610783|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|reactome:R-HSA-8941284|refseq:NP_005261.2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:j5ldspxY3p3hXtz+t9waBsqz0cQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q7Z5L2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-10262006|uniprotkb:Q5W0B5|uniprotkb:O60598|uniprotkb:Q86VT9|uniprotkb:Q8N9H0|uniprotkb:Q5W0B4|intact:EBI-28972220|ensembl:ENSP00000483494	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:r3hcl_human(display_long)|uniprotkb:R3HCC1L(gene name)|psi-mi:R3HCC1L(display_short)|uniprotkb:C10orf28(gene name synonym)|uniprotkb:GIDRP88(gene name synonym)|uniprotkb:Growth inhibition and differentiation-related protein 88(gene name synonym)|uniprotkb:Putative mitochondrial space protein 32.1(gene name synonym)|uniprotkb:R3H and coiled-coil domain-containing protein 1-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000370586|ensembl:ENSP00000359618|ensembl:ENSP00000483494|ensembl:ENST00000613938|ensembl:ENSP00000479916|refseq:NP_001243548.1|refseq:NP_001243549.1|refseq:NP_001243550.1|refseq:XP_011537942.1|refseq:XP_011537943.1|refseq:XP_011537944.1|refseq:XP_011537945.1|refseq:XP_011537946.1|refseq:XP_011537947.1|refseq:XP_011537948.1|refseq:XP_011537949.1|refseq:XP_011537950.1|refseq:XP_016871563.1|ensembl:ENSG00000166024(gene)|ensembl:ENST00000612478(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR039884	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:FfD13Ffu0/TQCcPL2CVYLtrvxS49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q92908	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2869259|uniprotkb:P78327|uniprotkb:B0YJ17|intact:EBI-28985406|ensembl:ENSP00000269216|ensembl:ENSP00000462313	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gata6_human(display_long)|uniprotkb:GATA6(gene name)|psi-mi:GATA6(display_short)|uniprotkb:GATA-binding factor 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005248.2|ensembl:ENSP00000269216|ensembl:ENSP00000462313|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070848"(response to growth factor)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098773"(skin epidermis development)|go:"GO:0048645"(animal organ formation)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|ensembl:ENSG00000141448(gene)|go:"GO:1904003"(negative regulation of sebum secreting cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028437|interpro:IPR039355|mint:Q92908|reactome:R-HSA-5683826|reactome:R-HSA-983231|go:"GO:1901390"(positive regulation of transforming growth factor beta activation)|ensembl:ENST00000269216(transcript)|ensembl:ENST00000581694(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001949"(sebaceous gland cell differentiation)|go:"GO:0002759"(regulation of antimicrobial humoral response)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007493"(endodermal cell fate determination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032912"(negative regulation of transforming growth factor beta2 production)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:+pEu3biPLYjs3/QiV/Ozi1HR9iY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96NZ1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11749712|uniprotkb:Q6ZMR4|uniprotkb:Q96NZ0|ensembl:ENSP00000299162	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:foxn4_human(display_long)|uniprotkb:FOXN4(gene name)|psi-mi:FOXN4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_998761.2|ensembl:ENSG00000139445(gene)|ensembl:ENST00000299162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001947"(heart looping)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010842"(retina layer formation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060579"(ventral spinal cord interneuron fate commitment)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:M7cKOvuTXpPKR95ox3I+dWfQy7A9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q12948	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1175253|uniprotkb:Q86UP7|uniprotkb:Q9BYM1|uniprotkb:Q9NUE5|uniprotkb:Q9UDD0|uniprotkb:Q9UP06|ensembl:ENSP00000493906	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:foxc1_human(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:FOXC1(gene name)|psi-mi:FOXC1(display_short)|uniprotkb:FKHL7(gene name synonym)|uniprotkb:FREAC3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000645831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|ensembl:ENSG00000054598(gene)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0008301"(DNA binding, bending)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0060038"(cardiac muscle cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|go:"GO:0070098"(chemokine-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|mint:Q12948|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|ensembl:ENSP00000493906|refseq:NP_001444.2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:+HuKwX8xMx86iCQW/a+vy/rWP389606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8TEU7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2693017|uniprotkb:Q8NI21|uniprotkb:Q96PC1|uniprotkb:Q8TEU6|uniprotkb:B7ZML2|uniprotkb:A3KN82|uniprotkb:A5PLL6|uniprotkb:E9PDV7|ensembl:ENSP00000421684	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rpgf6_human(display_long)|uniprotkb:PDZGEF2(gene name synonym)|uniprotkb:PDZ domain-containing guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RA-GEF-2(gene name synonym)|uniprotkb:RAPGEF6(gene name)|psi-mi:RAPGEF6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001157858.1|refseq:NP_001157859.1|refseq:NP_001157860.1|refseq:NP_001157861.1|refseq:NP_001157862.1|refseq:NP_057424.3|ensembl:ENST00000296859|ensembl:ENSP00000296859|ensembl:ENST00000308008|ensembl:ENSP00000311419|ensembl:ENST00000507093|ensembl:ENSP00000426081|ensembl:ENSP00000421684|ensembl:ENST00000510071|ensembl:ENSP00000425389|ensembl:ENST00000627212|ensembl:ENSP00000487439|ensembl:ENSG00000158987(gene)|ensembl:ENST00000509018(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000159(Ras-association)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR023578|interpro:IPR036034|rcsb pdb:2D93|rcsb pdb:3LNY	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:8kovsavvSAM+XwnQJYilOUEnXVg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H019	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2824497|uniprotkb:D3DPJ4|uniprotkb:A6NCB4|uniprotkb:Q63HP1|uniprotkb:B7WNV5|uniprotkb:Q9NUI7|uniprotkb:Q7Z2S7|ensembl:ENSP00000363418|ensembl:ENSP00000363419|ensembl:ENSP00000363421	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mfr1l_human(display_long)|uniprotkb:MTFR1L(gene name)|psi-mi:MTFR1L(display_short)|uniprotkb:FAM54B(gene name synonym)|uniprotkb:HYST1888(orf name)|uniprotkb:MSTP116(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001093095.1|refseq:NP_001093096.1|refseq:NP_001093097.1|refseq:NP_062457.3|interpro:IPR007972(Protein of unknown function DUF729)|ensembl:ENSG00000117640(gene)|ensembl:ENST00000374300(transcript)|ensembl:ENST00000374301(transcript)|ensembl:ENST00000374303(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0009060"(aerobic respiration)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:SVK2WRYbJLfAsZHMblHvoagnYoQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NYF3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1644252|uniprotkb:D3DQB9|uniprotkb:B2RDJ5|ensembl:ENSP00000239906|ensembl:ENSP00000403705	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:fa53c_human(display_long)|uniprotkb:FAM53C(gene name)|psi-mi:FAM53C(display_short)|uniprotkb:C5orf6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001129119.1|refseq:NP_057689.1|ensembl:ENSG00000120709(gene)|ensembl:ENST00000239906(transcript)|ensembl:ENST00000434981(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR029356	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:DOnDTyw+f+NYBQnR1iWWlajGf9I9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P78312	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2873877|uniprotkb:P78313|uniprotkb:P78311|uniprotkb:Q9UEG8|uniprotkb:O43607|uniprotkb:B7ZM85|uniprotkb:E9PFA1|uniprotkb:B9EGR0|ensembl:ENSP00000324587	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:f193a_human(display_long)|uniprotkb:FAM193A(gene name)|psi-mi:FAM193A(display_short)|uniprotkb:C4orf8(gene name synonym)|uniprotkb:Protein IT14(gene name synonym)|uniprotkb:RES4-22(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003695.3|refseq:XP_006713993.2|refseq:NP_001243595.1|refseq:NP_001243596.1|refseq:NP_001243597.1|ensembl:ENSP00000324587|ensembl:ENST00000382839|ensembl:ENSP00000372290|ensembl:ENSP00000427505|ensembl:ENST00000505311|ensembl:ENST00000502458|ensembl:ENSP00000421200|ensembl:ENST00000512465|ensembl:ENSP00000423852|ensembl:ENST00000545951|ensembl:ENSP00000443617|ensembl:ENSG00000125386(gene)|ensembl:ENST00000324666(transcript)|interpro:IPR029717|interpro:IPR029719|interpro:IPR031802	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:v0yZQ433SbBvEWkvwuNSZNebaD09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H7U1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-714702|uniprotkb:B7WPE8|uniprotkb:Q9ULU1|uniprotkb:Q9H2S0|intact:EBI-2558596|intact:EBI-1104827|uniprotkb:B4DQU9|uniprotkb:D3DWE2|uniprotkb:B4DFY4|uniprotkb:Q8N6E9|ensembl:ENSP00000224756	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ccse2_human(display_long)|uniprotkb:CCSER2(gene name)|psi-mi:CCSER2(display_short)|uniprotkb:Coiled-coil serine-rich protein 2(gene name synonym)|uniprotkb:FAM190B(gene name synonym)|uniprotkb:KIAA1128(gene name synonym)|uniprotkb:Protein GCAP14 homolog(gene name synonym)|uniprotkb:NPD012(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001271169.1|refseq:NP_001271170.1|refseq:NP_001271171.1|refseq:NP_001271172.1|refseq:NP_061872.2|ensembl:ENSG00000107771(gene)|ensembl:ENST00000224756(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR029627|interpro:IPR029629|refseq:XP_016871829.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:6kwn1v/e/MUOBgzpZVvbhxfCNZs9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5VUB5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2682893|uniprotkb:Q8N4I0|uniprotkb:Q32M49|uniprotkb:D3DRT9|ensembl:ENSP00000367356	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:f1711_human(display_long)|uniprotkb:APCN(gene name synonym)|uniprotkb:C10orf38(gene name synonym)|uniprotkb:Astroprincin(gene name synonym)|uniprotkb:FAM171A1(gene name)|psi-mi:FAM171A1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001010924.1|ensembl:ENSG00000148468(gene)|ensembl:ENST00000378116(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043149"(stress fiber assembly)|interpro:IPR018890	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:qZ5OSbTW7Jiy72ZLCSXrEBp0epU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:A1KXE4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2622099|uniprotkb:Q6NZ40|uniprotkb:Q2TAZ6|ensembl:ENSP00000374565|ensembl:ENSP00000387051	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:f168b_human(display_long)|uniprotkb:KIAA0280L(gene name synonym)|uniprotkb:p20(gene name synonym)|uniprotkb:FAM168B(gene name)|psi-mi:FAM168B(display_short)|uniprotkb:MANI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001308672.1|refseq:NP_001009993.2|refseq:XP_016858816.1|ensembl:ENSG00000152102(gene)|ensembl:ENST00000389915(transcript)|ensembl:ENST00000409185(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR029247|refseq:NP_001308673.1|refseq:NP_001308674.1|refseq:NP_001308675.1|refseq:NP_001308676.1|refseq:NP_001308677.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:b76fBaarMDthz23BFzK99JbKrWU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5JTC6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-6169747|uniprotkb:A2IB86|uniprotkb:Q8N885|ensembl:ENSP00000364003	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:amer1_human(display_long)|uniprotkb:AMER1(gene name)|psi-mi:AMER1(display_short)|uniprotkb:FAM123B(gene name synonym)|uniprotkb:Protein FAM123B(gene name synonym)|uniprotkb:WTX(gene name synonym)|uniprotkb:Wilms tumor gene on the X chromosome protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_689637.3|reactome:R-HSA-5467348|ensembl:ENSG00000184675(gene)|ensembl:ENST00000374869(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060348"(bone development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0072161"(mesenchymal cell differentiation involved in kidney development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904713"(beta-catenin destruction complex binding)|interpro:IPR019003|mint:Q5JTC6|rcsb pdb:4YJE|rcsb pdb:4YJL|rcsb pdb:4YK6|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:sRFifjRWQ45q8lSqsBPcCpYxM0Y9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96EK7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-739883|intact:EBI-1051176|uniprotkb:Q86V68|uniprotkb:Q96JI9|uniprotkb:B4DL34|ensembl:ENSP00000417970|ensembl:ENSP00000481344	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:f120b_human(display_long)|uniprotkb:FAM120B(gene name)|psi-mi:FAM120B(display_short)|uniprotkb:CCPG(gene name synonym)|uniprotkb:KIAA1838(gene name synonym)|uniprotkb:Protein FAM120B(gene name synonym)|uniprotkb:PPARG constitutive coactivator 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001273310.1|refseq:NP_115824.1|ensembl:ENSG00000112584(gene)|ensembl:ENSG00000275333(gene)|ensembl:ENST00000476287(transcript)|ensembl:ENST00000617082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR026784|interpro:IPR029060|reactome:R-HSA-1989781|reactome:R-HSA-381340	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ZJCJzICuVacQHYxYTIZw+6ODvEo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UJM3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2941912|intact:EBI-28986605|ensembl:ENSP00000366702|uniprotkb:B2RDX9|uniprotkb:Q9NTG9|uniprotkb:Q9UD05	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:errfi_human(display_long)|uniprotkb:ERRFI1(gene name)|psi-mi:ERRFI1(display_short)|uniprotkb:MIG6(gene name synonym)|uniprotkb:Mitogen-inducible gene 6 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000116285(gene)|ensembl:ENST00000377482(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0060426"(lung vasculature development)|go:"GO:0060428"(lung epithelium development)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR015116(GTPase binding)|interpro:IPR021619|mint:Q9UJM3|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:4I21|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4ZJV|refseq:NP_061821.1|refseq:XP_006710760.1|ensembl:ENSP00000366702|dip:DIP-42379N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:HRSCqWO9Ack7wplv68edTljW2IQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q92889	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2370770|uniprotkb:O00140|uniprotkb:Q8TD83|uniprotkb:A5PKV6|uniprotkb:A8K111|ensembl:ENSP00000310520	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:xpf_human(display_long)|uniprotkb:ERCC4(gene name)|psi-mi:ERCC4(display_short)|uniprotkb:ERCC11(gene name synonym)|uniprotkb:XPF(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-4(gene name synonym)|uniprotkb:DNA repair protein complementing XP-F cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group F-complementing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005227.1|dip:DIP-42006N|ensembl:ENSG00000175595(gene)|ensembl:ENST00000311895(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1905768"(negative regulation of double-stranded telomeric DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|mint:Q92889|rcsb pdb:1Z00|rcsb pdb:2A1J|rcsb pdb:2AQ0|rcsb pdb:2KN7|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6783310	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:A42t082dZNQH72TF3QRa+Msuoms9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q14247	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P48729	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|intact:EBI-11048253|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|ensembl:ENSP00000367074	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|dip:DIP-40367N|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6UUV7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-3453588|uniprotkb:Q9H6U2|uniprotkb:Q6DK61|uniprotkb:Q6DK62|uniprotkb:Q8NF38|ensembl:ENSP00000268184	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:crtc3_human(display_long)|uniprotkb:CRTC3(gene name)|psi-mi:CRTC3(display_short)|uniprotkb:TORC3(gene name synonym)|uniprotkb:Transducer of regulated cAMP response element-binding protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001036039.1|refseq:NP_073606.3|ensembl:ENSP00000268184|ensembl:ENST00000420329|ensembl:ENSP00000416573|dip:DIP-59211N|ensembl:ENSG00000140577(gene)|ensembl:ENST00000268184(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR024786|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-9707616|go:"GO:0005829"(cytosol)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0097009"(energy homeostasis)|interpro:IPR024783|interpro:IPR024784|interpro:IPR024785	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:OHoNJjikyJ3RLDd+Y23mUXbtLDA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q53ET0	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1181987|uniprotkb:Q7Z3X7|uniprotkb:Q6UUV8|uniprotkb:Q8N332|ensembl:ENSP00000357622	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:crtc2_human(display_long)|uniprotkb:TORC2(gene name synonym)|uniprotkb:Transducer of regulated cAMP response element-binding protein 2(gene name synonym)|uniprotkb:CRTC2(gene name)|psi-mi:CRTC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_859066.1|ensembl:ENSP00000357622|ensembl:ENSG00000160741(gene)|ensembl:ENST00000368633(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|interpro:IPR024783|interpro:IPR024784|interpro:IPR024785|interpro:IPR024786|mint:Q53ET0|rcsb pdb:4HTM|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-29950N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:p/QkUoueS1+KCLb0il8SMt8JwQM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q17RY0	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2848203|uniprotkb:Q7Z310|uniprotkb:Q9C0J0|uniprotkb:Q8N405|uniprotkb:B7ZLQ7|ensembl:ENSP00000265085	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cpeb4_human(display_long)|uniprotkb:CPEB4(gene name)|psi-mi:CPEB4(display_short)|uniprotkb:KIAA1673(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001295118.1|refseq:NP_001295120.1|refseq:NP_001295121.1|refseq:NP_001295122.1|refseq:NP_085130.2|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032296|interpro:IPR034819|interpro:IPR035979|interpro:IPR038446|mint:Q17RY0|rcsb pdb:2MKI|rcsb pdb:2MKJ|rcsb pdb:5DIF|ensembl:ENSG00000113742(gene)|ensembl:ENST00000265085(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:2wZUfRENqFZg7jJg+Yq+0CoI1vw9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NZN8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q15417	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2371691|uniprotkb:B4DFK6|uniprotkb:B4DP09|uniprotkb:F8WA86|uniprotkb:Q6FHA7|ensembl:ENSP00000359225	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cnn3_human(display_long)|uniprotkb:CNN3(gene name)|psi-mi:CNN3(display_short)|uniprotkb:Calponin, acidic isoform(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001830.1|refseq:NP_001272984.1|refseq:NP_001272985.1|refseq:XP_016855734.1|ensembl:ENSG00000117519(gene)|ensembl:ENST00000370206(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:UgeW769u9WgYLYNzTZ50xQqB5I09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9HAW4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1369377|uniprotkb:Q5VYG0|uniprotkb:Q6P6H5|uniprotkb:Q8IWI1|uniprotkb:A6NFL4|uniprotkb:Q1RMC6|uniprotkb:Q2KHM3|intact:EBI-28979386|ensembl:ENSP00000312995	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:clspn_human(display_long)|uniprotkb:CLSPN(gene name)|psi-mi:CLSPN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001317419.1|ensembl:ENST00000251195|ensembl:ENSP00000251195|ensembl:ENSP00000312995|ensembl:ENST00000373220|ensembl:ENSP00000362317|refseq:NP_001177410.1|refseq:NP_071394.2|ensembl:ENSG00000092853(gene)|ensembl:ENST00000318121(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|interpro:IPR024146|mint:Q9HAW4|rcsb pdb:7AKO|reactome:R-HSA-111465|reactome:R-HSA-176187|reactome:R-HSA-5689880|reactome:R-HSA-5693607	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:colqtYH36pqL6fhGk1RHAf8UJVU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6FI81	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-750511|uniprotkb:O75206|uniprotkb:O75207|uniprotkb:Q9H0W1|uniprotkb:Q9P1L7|uniprotkb:A8K8B6|ensembl:ENSP00000377914	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cpin1_human(display_long)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:CIAPIN1(gene name)|psi-mi:CIAPIN1(display_short)|uniprotkb:PRO0915(orf name)|uniprotkb:CUA001(orf name)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_064709.2|refseq:NP_001295276.1|refseq:NP_001295287.1|dip:DIP-61697N|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|rcsb pdb:2LD4|rcsb pdb:2YUI|rcsb pdb:4M7R|reactome:R-HSA-2564830|ensembl:ENSG00000005194(gene)|ensembl:ENST00000394391(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:80r/MAg7g8AcGJc7SGHsjE5aWiA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9HCK8	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENSP00000495240	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000430710|ensembl:ENSP00000406288|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENST00000645929|ensembl:ENSP00000494402|ensembl:ENSP00000495240|refseq:NP_001164100.1|refseq:NP_065971.2|go:"GO:0035064"(methylated histone binding)|go:"GO:0035176"(social behavior)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048565"(digestive tract development)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070615"|ensembl:ENSG00000100888(gene)|ensembl:ENST00000557364(transcript)|ensembl:ENST00000643469(transcript)|ensembl:ENST00000646647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|go:"GO:0071339"(MLL1 complex)|dip:DIP-38021N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:QwADLvHNwK00OAboBtAkqaICd489606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8IW35	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1566210|uniprotkb:Q8NA71|uniprotkb:Q9H5T9|uniprotkb:B5MDY8|intact:EBI-2560935|ensembl:ENSP00000342510	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cep97_human(display_long)|uniprotkb:LRRIQ2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:CEP97(gene name)|psi-mi:CEP97(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_078824.2|refseq:NP_001290330.1|ensembl:ENSG00000182504(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q8IW35|reactome:R-HSA-5620912|reactome:R-HSA-9013424|ensembl:ENST00000341893(transcript)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gz4rQbzgNiEg1X01O7YWz4TmfQA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6P2H3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2808308|ensembl:ENSP00000252992|uniprotkb:Q5VY68|uniprotkb:Q9H828|uniprotkb:Q9H6Q1|uniprotkb:Q5VY70|uniprotkb:Q9UF52|uniprotkb:D3DPK4|uniprotkb:B4DRL1|uniprotkb:F8W7K4	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cep85_human(display_long)|uniprotkb:CCDC21(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 21(gene name synonym)|uniprotkb:CEP85(gene name)|psi-mi:CEP85(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000130695(gene)|ensembl:ENST00000252992(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046602"(regulation of mitotic centrosome separation)|interpro:IPR029777|interpro:IPR040210|rcsb pdb:5OI7|rcsb pdb:5OID|refseq:NP_001306873.1|refseq:NP_073615.2|refseq:NP_001268446.1|refseq:NP_001268447.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:akTkilY7AIoc1FtkiNFwz4oelvI9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5SW79	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9HC77	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NYV4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1055431|uniprotkb:A7E2B2|uniprotkb:O94978|uniprotkb:B4DYX4|uniprotkb:B9EIQ6|ensembl:ENSP00000398880	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cdk12_human(display_long)|uniprotkb:Cdc2-related kinase, arginine/serine-rich(gene name synonym)|uniprotkb:CDK12(gene name)|psi-mi:CDK12(display_short)|uniprotkb:CRK7(gene name synonym)|uniprotkb:KIAA0904(gene name synonym)|uniprotkb:CRKRS(gene name synonym)|uniprotkb:Cell division cycle 2-related protein kinase 7(gene name synonym)|uniprotkb:Cell division protein kinase 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_055898.1|refseq:NP_057591.2|ensembl:ENST00000430627|ensembl:ENSP00000407720|ensembl:ENSP00000398880|ensembl:ENSG00000167258(gene)|ensembl:ENST00000447079(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0002944"(cyclin K-CDK12 complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019908"(nuclear cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4CXA|rcsb pdb:4NST|rcsb pdb:4UN0|rcsb pdb:5ACB|rcsb pdb:6B3E|rcsb pdb:6CKX|rcsb pdb:6TD3|rcsb pdb:7NXK|reactome:R-HSA-6796648|dip:DIP-39768N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:qffna20nodTj1PmlReV/ACpVcqs9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P30304	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-747671|uniprotkb:Q8IZH5|uniprotkb:Q96IL3|uniprotkb:Q9H2F2|ensembl:ENSP00000303706	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mpip1_human(display_long)|uniprotkb:Dual specificity phosphatase Cdc25A(gene name synonym)|uniprotkb:CDC25A(gene name)|psi-mi:CDC25A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001780.2|refseq:NP_963861.1|refseq:XP_011532618.1|dip:DIP-166N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|mint:P30304|rcsb pdb:1C25|reactome:R-HSA-1362277|reactome:R-HSA-156711|reactome:R-HSA-176187|go:"GO:0004725"(protein tyrosine phosphatase activity)|reactome:R-HSA-5689880|reactome:R-HSA-69273|reactome:R-HSA-69601|reactome:R-HSA-69656|reactome:R-HSA-8862803|reactome:R-HSA-69202|ensembl:ENSG00000164045(gene)|ensembl:ENST00000302506(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004721"(phosphoprotein phosphatase activity)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:CgQErDZyEXEPS4+zxb2vFhzYD4c9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O43303	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gvda4RoDRcY+G50iRW5T+haubps9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q16204	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1045350|uniprotkb:Q15250|uniprotkb:Q6GSG7|ensembl:ENSP00000263102	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ccdc6_human(display_long)|uniprotkb:Protein H4(gene name synonym)|uniprotkb:Papillary thyroid carcinoma-encoded protein(gene name synonym)|uniprotkb:CCDC6(gene name)|psi-mi:CCDC6(display_short)|uniprotkb:D10S170(gene name synonym)|uniprotkb:TST1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_005427.2|ensembl:ENSG00000108091(gene)|ensembl:ENST00000263102(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR019152	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:nPX3jyRnTSavY0tKyxDiVo35n8E9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y4B5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-302423|uniprotkb:Q6ZMQ9|uniprotkb:Q8IWA9|intact:EBI-28975975|ensembl:ENSP00000305027|intact:EBI-2554582|uniprotkb:E9PAY7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mtcl1_human(display_long)|uniprotkb:MTCL1(gene name)|psi-mi:MTCL1(display_short)|uniprotkb:CCDC165(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 165(gene name synonym)|uniprotkb:KIAA0802(gene name synonym)|uniprotkb:PAR-1-interacting protein(gene name synonym)|uniprotkb:SOGA family member 2(gene name synonym)|uniprotkb:SOGA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_056025.2|ensembl:ENSG00000168502(gene)|ensembl:ENST00000306329(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008017"(microtubule binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097427"(microtubule bundle)|go:"GO:2000576"(obsolete positive regulation of microtubule motor activity)|interpro:IPR027881|interpro:IPR027882|ensembl:ENSP00000305027|ensembl:ENST00000359865|ensembl:ENSP00000352927|ensembl:ENST00000400050|ensembl:ENSP00000382924|ensembl:ENSP00000429556|ensembl:ENST00000518815|ensembl:ENSP00000463465|ensembl:ENST00000517570|refseq:XP_005258156.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:RxNB5mpEiLNQpsyKLfaw0LyqsVU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q86X55	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453(gene)|ensembl:ENST00000327064(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0034971"(histone H3-R17 methylation)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035642"("histone methyltransferase activity (H3-R17 specific)")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|go:"GO:0051591"(response to cAMP)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P47756	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q08AD1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1051869|uniprotkb:B1APG6|uniprotkb:Q08AD2|uniprotkb:Q6PGN8|uniprotkb:Q96FB3|uniprotkb:Q9UG20|uniprotkb:Q9UPS4|ensembl:ENSP00000236925	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:camp2_human(display_long)|uniprotkb:KIAA1078(gene name synonym)|uniprotkb:CAMSAP2(gene name)|psi-mi:CAMSAP2(display_short)|uniprotkb:CAMSAP1L1(gene name synonym)|uniprotkb:Calmodulin-regulated spectrin-associated protein 1-like protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_982284.1|refseq:NP_001284636.1|refseq:NP_001284637.1|ensembl:ENSP00000236925|ensembl:ENST00000358823|ensembl:ENSP00000351684|ensembl:ENST00000413307|ensembl:ENSP00000416800|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|go:"GO:1990752"(microtubule end)|ensembl:ENSG00000118200(gene)|ensembl:ENST00000236925(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0033043"(regulation of organelle organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0061564"(axon development)|go:"GO:1903358"(regulation of Golgi organization)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:dYxSv8D6Jw1iRvPJ0nsmLdiEcz09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5T5Y3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2837196|uniprotkb:Q96E80|uniprotkb:B2REB2|uniprotkb:Q70W33|uniprotkb:Q96FM3|uniprotkb:Q9UFJ5|uniprotkb:B2REB3|uniprotkb:Q8NCY0|uniprotkb:A1L4L2|intact:EBI-28978395|ensembl:ENSP00000374183	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:camp1_human(display_long)|uniprotkb:CAMSAP1(gene name)|psi-mi:CAMSAP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000312405|ensembl:ENSP00000312463|ensembl:ENSP00000374183|ensembl:ENST00000409386|ensembl:ENSP00000386420|refseq:NP_056262.3|refseq:XP_005263453.1|refseq:XP_005263454.1|ensembl:ENSG00000130559(gene)|ensembl:ENST00000389532(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|mint:Q5T5Y3|rcsb pdb:5M54|rcsb pdb:5M5C|rcsb pdb:6QUS|rcsb pdb:6QVJ	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:XiwTTDbfEBck/Ch8X2KYzBbPzOc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O43822	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2835332|uniprotkb:O14993|uniprotkb:A8MPS9|uniprotkb:Q99838|uniprotkb:Q99837|uniprotkb:Q8N5X6|ensembl:ENSP00000344566	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cf410_human(display_long)|uniprotkb:CFAP410(gene name)|psi-mi:CFAP410(display_short)|uniprotkb:C21orf-HUMF09G8.5(gene name synonym)|uniprotkb:C21orf2(gene name synonym)|uniprotkb:LRRC76(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 76(gene name synonym)|uniprotkb:YF5/A2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_004919.1|refseq:NP_001258369.1|refseq:NP_001258370.1|refseq:NP_001258371.1|ensembl:ENSG00000160226(gene)|ensembl:ENST00000339818(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060271"(cilium assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:YHYO3FIkJspPgIlVemxIOEL6t2w9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H0I2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-744099|uniprotkb:Q6UWD7|ensembl:ENSP00000243878	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:enkd1_human(display_long)|uniprotkb:ENKD1(gene name)|psi-mi:ENKD1(display_short)|uniprotkb:C16orf48(gene name synonym)|uniprotkb:UNQ6410/PRO21183(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_115516.1|ensembl:ENSG00000124074(gene)|ensembl:ENST00000243878(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0097546"(ciliary base)|interpro:IPR027012|interpro:IPR027710|mint:Q9H0I2	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:kLnlpnGpF+sgQ+umqiN1CIK/7wc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q99622	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2808472|ensembl:ENSP00000229281|ensembl:ENSP00000440602|uniprotkb:B2R4Q6	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:c10_human(display_long)|uniprotkb:C12orf57(gene name)|psi-mi:C12orf57(display_short)|uniprotkb:C10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001288763.1|ensembl:ENSG00000111678(gene)|ensembl:ENST00000229281(transcript)|ensembl:ENST00000545581(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021678"(third ventricle development)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050890"(cognition)|interpro:IPR026317|refseq:NP_612434.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:RQA3V8/ja1T1aBhtzEYvka2r7iQ9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P51587	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P38398	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6PGQ7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-719836|uniprotkb:Q5W0P3|uniprotkb:Q5W0P4|uniprotkb:Q86YC6|uniprotkb:Q96IW9|uniprotkb:Q9H640|intact:EBI-2560951|ensembl:ENSP00000375082|ensembl:ENSP00000498664|uniprotkb:B4DQ30	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:bora_human(display_long)|uniprotkb:BORA(gene name)|psi-mi:BORA(display_short)|uniprotkb:C13orf34(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000136122(gene)|ensembl:ENST00000390667(transcript)|ensembl:ENST00000651477(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072687"(meiotic spindle)|interpro:IPR023252|reactome:R-HSA-2565942|refseq:NP_001273675.1|refseq:NP_001273676.1|refseq:NP_079084.3|dip:DIP-53424N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:NnEXfCqCEQPKk7KG1RiJyxHrgg09606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NSY1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1383367|uniprotkb:O94791|uniprotkb:Q8IYF2|uniprotkb:Q8N2G7|uniprotkb:Q8NHG9|uniprotkb:Q9NTG8|uniprotkb:Q4W5H2|intact:EBI-28972938|ensembl:ENSP00000424668	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:bmp2k_human(display_long)|uniprotkb:BMP2K(gene name)|psi-mi:BMP2K(display_short)|uniprotkb:BIKE(gene name synonym)|uniprotkb:HRIHFB2017(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000424668|ensembl:ENST00000502871|ensembl:ENSP00000421768|refseq:NP_060063.2|refseq:NP_942595.1|ensembl:ENSG00000138756(gene)|ensembl:ENST00000502613(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026105|interpro:IPR028182|rcsb pdb:4W9W|rcsb pdb:4W9X|rcsb pdb:5I3O|rcsb pdb:5I3R|rcsb pdb:5IKW|go:"GO:0019208"(phosphatase regulator activity)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:ckhpP0erhSRURf04YvQFCsYZ8rY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O15169	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-710484|uniprotkb:Q4TT26|uniprotkb:Q4TT27|ensembl:ENSP00000262320|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003493.1|refseq:NP_851393.1|ensembl:ENSG00000103126(gene)|ensembl:ENST00000262320(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR029797|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|dip:DIP-34630N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q7Z3C6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:arvq+TjXETr14g/FkOITnLfYVh89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9C0H5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-11277939|uniprotkb:B4E1I1|ensembl:ENSP00000276826	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rhg39_human(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001295136.1|refseq:NP_001295137.1|refseq:NP_079527.1|refseq:XP_011515610.1|refseq:XP_011515611.1|ensembl:ENSG00000147799(gene)|ensembl:ENST00000276826(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR000198(RhoGAP)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036020|interpro:IPR038185|reactome:R-HSA-428543|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|refseq:XP_016869359.1|refseq:XP_016869360.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:du3vJMrTsmg7cyZrI+inLExctXE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:A7KAX9	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-308663|uniprotkb:Q86YL6|intact:EBI-1210177|uniprotkb:O94820|uniprotkb:Q8IUG4|uniprotkb:Q9BWG3|ensembl:ENSP00000310561|uniprotkb:I7H0B0	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rhg32_human(display_long)|uniprotkb:ARHGAP32(gene name)|psi-mi:ARHGAP32(display_short)|uniprotkb:GRIT(gene name synonym)|uniprotkb:KIAA0712(gene name synonym)|uniprotkb:RICS(gene name synonym)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:GTPase regulator interacting with TrkA(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	go:"GO:0005938"(cell cortex)|ensembl:ENSP00000310561|ensembl:ENST00000392657|ensembl:ENSP00000376425|ensembl:ENST00000527272|ensembl:ENSP00000432862|ensembl:ENSG00000134909(gene)|ensembl:ENST00000310343(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036028|interpro:IPR036871|interpro:IPR042139|mint:A7KAX9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|rcsb pdb:3IUG|refseq:NP_001136157.1|refseq:NP_055530.2|go:"GO:0007264"(small GTPase mediated signal transduction)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:V51KfHcAYYMGvIsWaG5hNqZ49Yk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5T5U3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1642518|uniprotkb:Q8NI19|uniprotkb:Q0VF98|uniprotkb:Q7Z3P7|uniprotkb:Q8N3A2|uniprotkb:Q8TBV5|uniprotkb:Q9P2C3|ensembl:ENSP00000379709	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rhg21_human(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 21(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_065875.3|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9013148|ensembl:ENSG00000107863(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051645"(Golgi localization)|ensembl:ENST00000396432(transcript)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|mint:Q5T5U3|rcsb pdb:2DHJ|rcsb pdb:2J59|rcsb pdb:2YUY|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9013106|refseq:XP_005252599.1|refseq:XP_016871948.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9NP61	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2875816|ensembl:ENSP00000263245|uniprotkb:Q9Y4V4|uniprotkb:Q9NUP5|uniprotkb:Q9Y4V3|uniprotkb:Q9NT10|uniprotkb:Q9BSC6|uniprotkb:Q9H9J0|uniprotkb:E9PB03	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:arfg3_human(display_long)|uniprotkb:ARFGAP3(gene name)|psi-mi:ARFGAP3(display_short)|uniprotkb:ARFGAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000242247(gene)|ensembl:ENST00000263245(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:2CRW|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-9013148|reactome:R-HSA-9013408|go:"GO:0005096"(GTPase activator activity)|refseq:NP_001135765.1|refseq:NP_055385.3	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:1868s5elsn/sX/f8if3lmbLxKxg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P25054	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-727707|uniprotkb:Q15162|uniprotkb:Q15163|uniprotkb:Q93042|uniprotkb:D3DT03|uniprotkb:B7Z2B6|ensembl:ENSP00000257430|ensembl:ENSP00000427089	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:apc_human(display_long)|uniprotkb:APC(gene name)|psi-mi:APC(display_short)|uniprotkb:DP2.5(gene name synonym)|uniprotkb:Deleted in polyposis 2.5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_000029.2|refseq:NP_001120982.1|dip:DIP-33556N|refseq:NP_001120983.2|ensembl:ENSG00000134982(gene)|ensembl:ENST00000257430(transcript)|ensembl:ENST00000508376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007155"(cell adhesion)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009232(EB-1 binding)|interpro:IPR009234(APC basic)|interpro:IPR009240(APC 15 residue)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026836|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:P25054|rcsb pdb:1DEB|rcsb pdb:1EMU|rcsb pdb:1JPP|rcsb pdb:1M5I|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:1V18|rcsb pdb:2RQU|rcsb pdb:3AU3|rcsb pdb:3NMW|rcsb pdb:3NMX|rcsb pdb:3NMZ|rcsb pdb:3QHE|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3T7U|rcsb pdb:4G69|rcsb pdb:4YJE|rcsb pdb:4YJL|rcsb pdb:4YK6|rcsb pdb:5B6G|rcsb pdb:5IZ6|rcsb pdb:5IZ8|rcsb pdb:5IZ9|rcsb pdb:5IZA|rcsb pdb:5Z8H|reactome:R-HSA-111465|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-3769402|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467333|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689896	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:BLZJqb4+lTr7gs2vgkXMvuwG+KU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q4VCS5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13085-3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-12503138|ensembl:ENSP00000480031|ensembl:ENSP00000482368	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:q13085-3(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)|uniprotkb:E5B(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	intact:EBI-717681(isoform-parent)|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000617649(transcript)|ensembl:ENST00000621312(transcript)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:lvBCDPuKpD2zWTdmes4XVgw3MYY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q13085	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96RT7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2555074|uniprotkb:Q9UGX3|uniprotkb:Q9UGX4|uniprotkb:Q5JZ80|uniprotkb:Q6PJ40|uniprotkb:Q9BY91|uniprotkb:Q86YE9|ensembl:ENSP00000248846	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gcp6_human(display_long)|uniprotkb:GCP6(gene name synonym)|uniprotkb:KIAA1669(gene name synonym)|uniprotkb:TUBGCP6(gene name)|psi-mi:TUBGCP6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_065194.2|ensembl:ENSG00000128159(gene)|ensembl:ENST00000248846(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|rcsb pdb:6M33|rcsb pdb:6V6C|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:H5Y8PvMXPZTmeJUq8yOQbPZ2jYY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P04637	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q8ND83	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-10269374|uniprotkb:Q5T6P7|uniprotkb:B7Z209|uniprotkb:A8K0Z9|uniprotkb:Q5T6P4|uniprotkb:Q8ND10|uniprotkb:Q96NV0|intact:EBI-28969016|ensembl:ENSP00000419730	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:slai1_human(display_long)|uniprotkb:SLAIN1(gene name)|psi-mi:SLAIN1(display_short)|uniprotkb:C13orf32(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000314070|ensembl:ENSP00000314443|ensembl:ENST00000358679|ensembl:ENSP00000351507|ensembl:ENSP00000419730|ensembl:ENST00000488699|ensembl:ENSP00000418707|refseq:NP_001035243.2|refseq:NP_001229798.1|refseq:NP_001229799.1|refseq:NP_653196.1|refseq:XP_011533232.1|ensembl:ENSG00000139737(gene)|ensembl:ENST00000466548(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|interpro:IPR026179	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:l7uzMoCwEFGRtqMOtHbnab7IrKM9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9Y2K2	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1181460|intact:EBI-1384133|uniprotkb:Q59FY2|uniprotkb:Q5M9N1|uniprotkb:Q6P3R6|uniprotkb:Q8IYM8|uniprotkb:Q9HA50|uniprotkb:H0Y494|uniprotkb:J3KPC8|ensembl:ENSP00000364449|uniprotkb:A1A5A8	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:sik3_human(display_long)|uniprotkb:QSK(gene name synonym)|uniprotkb:KIAA0999(gene name synonym)|uniprotkb:SIK3(gene name)|psi-mi:SIK3(display_short)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:L19(orf name)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_079440.3|ensembl:ENSG00000160584(gene)|ensembl:ENST00000375300(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672|refseq:NP_001268678.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:YZTDZCOcd7R9N57N7J/iFkCxzwo9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5W0B1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2562035|uniprotkb:Q9H8M0|uniprotkb:B2RN99|uniprotkb:Q9H0T2|uniprotkb:Q8TBY2|ensembl:ENSP00000282003	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:obi1_human(display_long)|uniprotkb:OBI1(gene name)|psi-mi:OBI1(display_short)|uniprotkb:C13orf7(gene name synonym)|uniprotkb:RING finger protein 219(gene name synonym)|uniprotkb:RNF219(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_078822.3|ensembl:ENSG00000152193(gene)|ensembl:ENST00000282003(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR035691|interpro:IPR039209|mint:Q5W0B1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:MCzyMLZ+OMynQerFlsiwIHPRc0M9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q04206	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q04864	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-307352|uniprotkb:Q2PNZ7|uniprotkb:Q6LDY0|ensembl:ENSP00000295025|intact:EBI-11133860|uniprotkb:Q17RU2	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:rel_human(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_002899.1|ensembl:ENSG00000162924(gene)|ensembl:ENST00000295025(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030505|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|interpro:IPR042845|mint:Q04864|reactome:R-HSA-1169091|ensembl:ENSP00000295025|ensembl:ENST00000394479|ensembl:ENSP00000377989|refseq:NP_001278675.1|dip:DIP-301N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:pcMbZU8647eKKyub9wOL93NK6VE9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H4L5	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1051317|uniprotkb:O14591|uniprotkb:O43357|uniprotkb:O43358|uniprotkb:Q8N702|uniprotkb:Q8N703|uniprotkb:Q8N704|uniprotkb:Q8NFH0|uniprotkb:Q8NFH1|uniprotkb:Q8NI12|uniprotkb:Q8NI13|uniprotkb:Q9BZF4|uniprotkb:Q9UED6|uniprotkb:B8ZZ79|uniprotkb:B8ZZP0|uniprotkb:A4D167|uniprotkb:A4D168|uniprotkb:A4D169|uniprotkb:A4D170|uniprotkb:A4D171|uniprotkb:A4D172|intact:EBI-28979334|ensembl:ENSP00000315410	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:osbl3_human(display_long)|uniprotkb:OSBPL3(gene name)|psi-mi:OSBPL3(display_short)|uniprotkb:KIAA0704(gene name synonym)|uniprotkb:ORP3(gene name synonym)|uniprotkb:OSBP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_056365.1|refseq:NP_663160.1|refseq:NP_663161.1|refseq:NP_663162.1|refseq:XP_011513560.1|ensembl:ENSP00000315410|ensembl:ENST00000396429|ensembl:ENSP00000379706|ensembl:ENST00000396431|ensembl:ENSP00000379708|ensembl:ENST00000409069|ensembl:ENSP00000386953|ensembl:ENST00000409452|ensembl:ENSP00000386801|ensembl:ENST00000409555|ensembl:ENSP00000386990|ensembl:ENST00000409759|ensembl:ENSP00000386325|ensembl:ENST00000409863|ensembl:ENSP00000386429|refseq:XP_005249755.1|refseq:XP_006715744.1|refseq:XP_006715745.1|refseq:XP_006715746.1|ensembl:ENSG00000070882(gene)|ensembl:ENST00000313367(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|mint:Q9H4L5|rcsb pdb:7CYZ|rcsb pdb:7DEI|rcsb pdb:7DEJ|reactome:R-HSA-192105	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:kiT2v1pGFlF+1s8wGhNidJyRbYc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UM47	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q04721	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001186930.1|refseq:NP_077719.2|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046849"(bone remodeling)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072104"(glomerular capillary formation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1990705"(cholangiocyte proliferation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001204"(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0035622"(intrahepatic bile duct development)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022336|interpro:IPR010660(Notch, NOD region)|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|ensembl:ENSG00000134250(gene)|ensembl:ENST00000256646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001947"(heart looping)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035264"(multicellular organism growth)	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O43318	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q16665	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-447269|uniprotkb:Q53XP6|uniprotkb:Q96PT9|uniprotkb:Q9UPB1|uniprotkb:C0LZJ3|ensembl:ENSP00000338018	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:hif1a_human(display_long)|uniprotkb:ARNT-interacting protein(gene name synonym)|uniprotkb:Member of PAS protein 1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)|uniprotkb:HIF1A(gene name)|psi-mi:HIF1A(display_short)|uniprotkb:MOP1(gene name synonym)|uniprotkb:BHLHE78(gene name synonym)|uniprotkb:PASD8(gene name synonym)|uniprotkb:PAS domain-containing protein 8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001230013.1|refseq:NP_001521.1|refseq:NP_851397.1|ensembl:ENST00000323441|ensembl:ENSP00000323326|ensembl:ENSP00000338018|ensembl:ENST00000539097|ensembl:ENSP00000437955|dip:DIP-29722N|ensembl:ENSG00000100644(gene)|ensembl:ENST00000337138(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q16665|rcsb pdb:1D7G|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1L3E|rcsb pdb:1L8C|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:2ILM|rcsb pdb:3HQR|rcsb pdb:3HQU|rcsb pdb:4AJY|rcsb pdb:4H6J|rcsb pdb:5JWP|rcsb pdb:5L9B|rcsb pdb:5L9V|rcsb pdb:5LA9|rcsb pdb:5LAS|rcsb pdb:6GFX|rcsb pdb:6GMR|rcsb pdb:6YW3|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|reactome:R-HSA-2122947|reactome:R-HSA-400253|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8849473|reactome:R-HSA-8857538|reactome:R-HSA-8951664	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:3XRt8HFMCRlxcYR2KfuFSq6gVBg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O15379	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-607682|uniprotkb:O43268|uniprotkb:Q9UEI5|uniprotkb:Q9UEV0|uniprotkb:D3DQE1|ensembl:ENSP00000302967	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:hdac3_human(display_long)|uniprotkb:HDAC3(gene name)|psi-mi:HDAC3(display_short)|uniprotkb:RPD3-2(gene name synonym)|uniprotkb:SMAP45(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_003874.2|dip:DIP-24253N|ensembl:ENSG00000171720(gene)|ensembl:ENST00000305264(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O15379|rcsb pdb:4A69|reactome:R-HSA-1368071|reactome:R-HSA-193670|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-390471|reactome:R-HSA-400206|reactome:R-HSA-5617472|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-400253	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:X5pnE98s15eXKev3nauN7ri5kqg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H6D7	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2558168|uniprotkb:Q86U43|uniprotkb:Q86T16|uniprotkb:Q86T15|uniprotkb:Q9NX59|uniprotkb:B7WP17|uniprotkb:D3DS34|ensembl:ENSP00000206474|ensembl:ENSP00000441026	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:haus4_human(display_long)|uniprotkb:HAUS4(gene name)|psi-mi:HAUS4(display_short)|uniprotkb:C14orf94(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001159741.1|refseq:NP_001159742.1|refseq:NP_060285.2|dip:DIP-48837N|ensembl:ENSG00000092036(gene)|ensembl:ENST00000206474(transcript)|ensembl:ENST00000541587(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026214|interpro:IPR029327|mint:Q9H6D7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:KWVJQqpFmFVFufH4Pq2Ecvp7SUA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9UKJ3	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-948259|ensembl:ENSP00000467556|uniprotkb:B9EGP9|uniprotkb:Q8TB99|uniprotkb:O60300	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:gptc8_human(display_long)|uniprotkb:GPATCH8(gene name)|psi-mi:GPATCH8(display_short)|uniprotkb:GPATC8(gene name synonym)|uniprotkb:KIAA0553(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000186566(gene)|ensembl:ENST00000591680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|refseq:NP_001002909.1|refseq:NP_001291868.1|refseq:NP_001291869.1|refseq:NP_001291870.1|refseq:NP_001291871.1|refseq:NP_001291872.1|refseq:XP_016879864.1|refseq:XP_016879865.1|refseq:XP_016879866.1|refseq:XP_016879867.1|refseq:XP_016879868.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:moPN1LjhDaFc24jYnKyPhgWHiF89606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9P2D6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2685819|uniprotkb:Q5JXK0|uniprotkb:Q9H0F2|uniprotkb:Q68DW0|uniprotkb:Q6P081|uniprotkb:Q9NXL5|uniprotkb:Q9NU48|uniprotkb:A2RRQ5|uniprotkb:Q5JXK1|uniprotkb:Q9NUQ5|uniprotkb:Q3C0H3|ensembl:ENSP00000359510|ensembl:ENSP00000410768	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:f135a_human(display_long)|uniprotkb:KIAA1411(gene name synonym)|uniprotkb:FAM135A(gene name)|psi-mi:FAM135A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001099001.1|refseq:NP_001156001.1|refseq:NP_065870.3|refseq:NP_001317926.1|refseq:NP_001317930.1|refseq:NP_001317931.1|refseq:XP_016866614.1|refseq:XP_016866615.1|refseq:XP_016866616.1|ensembl:ENSG00000082269(gene)|ensembl:ENST00000370479(transcript)|ensembl:ENST00000418814(transcript)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR007751(Protein of unknown function DUF676, hydrolase-like)|interpro:IPR022122|interpro:IPR029058|interpro:IPR044294|reactome:R-HSA-9696273	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:eOitcL5fc1tMBNKlAubhp3KrrXY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96F86	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q96N67	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2433703|uniprotkb:Q00M63|uniprotkb:Q2PPY7|uniprotkb:Q45RE8|uniprotkb:Q45RE9|uniprotkb:Q5T1B9|uniprotkb:Q5T1C0|uniprotkb:Q6ZV32|uniprotkb:Q8TB82|uniprotkb:Q96NG6|uniprotkb:Q9C092|intact:EBI-7303260|intact:MINT-1683616|uniprotkb:Q96NI0|intact:EBI-28980506|ensembl:ENSP00000489124	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:dock7_human(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011540628.1|refseq:NP_001258931.1|refseq:NP_212132.2|ensembl:ENST00000251157|ensembl:ENSP00000251157|ensembl:ENST00000340370|ensembl:ENSP00000340742|ensembl:ENST00000404627|ensembl:ENSP00000384446|ensembl:ENST00000454575|ensembl:ENSP00000413583|ensembl:ENST00000634264|ensembl:ENSP00000489284|ensembl:ENST00000635123|ensembl:ENSP00000489499|ensembl:ENSP00000489124|refseq:NP_001258928.1|refseq:NP_001258929.1|refseq:NP_001258930.1|refseq:NP_001317543.1|ensembl:ENSG00000116641(gene)|ensembl:ENST00000635253(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0045178"(basal part of cell)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|mint:Q96N67|rcsb pdb:6AJ4|rcsb pdb:6AJL|reactome:R-HSA-8875555|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:PHjIS0j8JJ6Il3knhzjCzMNkxKk9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:A5YKK6	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q99439	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-2961712|ensembl:ENSP00000263097|uniprotkb:Q92578|uniprotkb:A5D8U8|uniprotkb:D6W5X9|uniprotkb:A6NFI4	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:cnn2_human(display_long)|uniprotkb:CNN2(gene name)|psi-mi:CNN2(display_short)|uniprotkb:Calponin H2, smooth muscle(gene name synonym)|uniprotkb:Neutral calponin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000064666(gene)|ensembl:ENST00000263097(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045296"(cadherin binding)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029974|interpro:IPR036872|rcsb pdb:1WYN|reactome:R-HSA-6798695|reactome:R-HSA-8950505|refseq:NP_004359.1|refseq:NP_958434.1|refseq:NP_001290428.1|refseq:NP_001290430.1	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:64KRSh4MEocrTZ8EuTz9ni8ahhc9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q14008	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q6W2J9	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q9H6S1	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-359973|intact:EBI-1384309|uniprotkb:Q86W99|uniprotkb:Q9BQF1|uniprotkb:A8K3M2|ensembl:ENSP00000419371|uniprotkb:C9JB40|uniprotkb:H7BXU6	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:azi2_human(display_long)|uniprotkb:AZI2(gene name)|psi-mi:AZI2(display_short)|uniprotkb:NAP1(gene name synonym)|uniprotkb:TBKBP2(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase-associated protein 1(gene name synonym)|uniprotkb:TILP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_001127904.1|refseq:NP_001127905.1|refseq:NP_071906.1|ensembl:ENSG00000163512(gene)|ensembl:ENST00000479665(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042110"(T cell activation)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0097028"(dendritic cell differentiation)|interpro:IPR024581|rcsb pdb:5EP6|rcsb pdb:5Z7G|rcsb pdb:5Z7L|refseq:XP_005265449.1|dip:DIP-27605N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:lfjd4cD2rm6NOjdh3XTTuFxnK9A9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:Q5T9A4	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:2W52iPQhTBU2apShm8xhfenV1mU9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:P27540	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-80809|uniprotkb:C4AMA1|ensembl:ENSP00000351407|uniprotkb:B2R9H1|uniprotkb:F8WAP6|uniprotkb:Q59ED4|uniprotkb:Q5QP39|uniprotkb:Q8NDC7	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:arnt_human(display_long)|uniprotkb:ARNT(gene name)|psi-mi:ARNT(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym)|uniprotkb:BHLHE2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSG00000143437(gene)|ensembl:ENST00000358595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|refseq:NP_001184254.1|refseq:NP_001659.1|refseq:NP_848514.1|refseq:NP_001272964.1|refseq:NP_001272965.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:P27540|rcsb pdb:1D7G|rcsb pdb:1X0O|rcsb pdb:2A24|rcsb pdb:2ARN|rcsb pdb:2B02|rcsb pdb:2HV1|rcsb pdb:2K7S|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6X21|rcsb pdb:3H82|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:4EQ1|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4H6J|rcsb pdb:4LPZ|rcsb pdb:4PKY|rcsb pdb:4XT2|reactome:R-HSA-1234158|rcsb pdb:5TBM|reactome:R-HSA-1989781|reactome:R-HSA-211945|rcsb pdb:5UFP|reactome:R-HSA-211976|reactome:R-HSA-211981|rcsb pdb:5V0L|rcsb pdb:6CZW|reactome:R-HSA-8937144|ensembl:ENST00000354396|ensembl:ENSP00000346372|ensembl:ENSP00000351407|ensembl:ENST00000505755|ensembl:ENSP00000427571|ensembl:ENST00000515192|ensembl:ENSP00000423851|refseq:XP_016856778.1|dip:DIP-30886N	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:MAYVa32fLDGxgEr0VL9ZVg/EcIA9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H6Z9	uniprotkb:O96018	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-6115839|uniprotkb:O60483|uniprotkb:Q9UPZ2|intact:EBI-28977865|ensembl:ENSP00000315136	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:apba3_human(display_long)|uniprotkb:APBA3(gene name)|psi-mi:APBA3(display_short)|uniprotkb:MINT3(gene name synonym)|uniprotkb:X11L2(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503146|imex:IM-22750-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	ensembl:ENSP00000315136|refseq:NP_004877.1|ensembl:ENSG00000011132(gene)|ensembl:ENST00000316757(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030531|interpro:IPR036034|rcsb pdb:2YT7|rcsb pdb:2YT8|rcsb pdb:5UWS|reactome:R-HSA-6794361	-	-	-	figure legend:Table S2|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: UBAP2L (UniProtKB accessions: Q14157;Q14157-1;Q14157-3;Q14157-4); CDK11B,CDK11A,CDC2L2 (UniProtKB accessions: P21127;Q9UQ88); GTF2H2,GTF2H2C,GTF2H2B (UniProtKB accessions: Q13888;Q6P1K8); HOXA1,HOXD1,HOXB1 (UniProtKB accessions: P14653;P49639;Q9GZZ0); PBX1,PBX2,PBX3 (UniProtKB accessions: P40424;P40425;P40426); POLR2J1,POLR2J,POLR2J3,POLR2J2 (UniProtKB accessions: P52435;Q9GZM3;Q9H1A7); PRKACA,PRKACB (UniProtKB accessions: P17612;P22694)."|comment:HC-partners were those specifically enriched in DMOG treated vs untreated ttest p-value <0.01 AND ratio>2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2019/02/20	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:9XKJCGIewG6Lx84WB+IkWXcDj3E9606	rigid:LS9TBPHjpI4GzoddsMiAttJtFvQ	false	v5 tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P18754	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-992720|uniprotkb:Q16269|uniprotkb:Q6NT97|ensembl:ENSP00000362939|ensembl:ENSP00000381931|ensembl:ENSP00000508074|ensembl:ENSP00000362938	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rcc1_human(display_long)|uniprotkb:Chromosome condensation protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein(gene name synonym)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)|uniprotkb:CHC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001041659.1|refseq:NP_001041660.1|refseq:NP_001041664.1|refseq:NP_001260.1|dip:DIP-35416N|ensembl:ENSG00000180198(gene)|ensembl:ENST00000373832(transcript)|ensembl:ENST00000373833(transcript)|ensembl:ENST00000398958(transcript)|ensembl:ENST00000683442(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016032"(viral process)|rcsb pdb:5E1B|rcsb pdb:5E1D|rcsb pdb:5E1M|rcsb pdb:5E1O|rcsb pdb:5E2A|go:"GO:0031267"(small GTPase binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031492"(nucleosomal DNA binding)|rcsb pdb:5E2B|rcsb pdb:5TBK|rcsb pdb:6DUB|reactome:R-HSA-165054|go:"GO:0031965"(nuclear membrane)|reactome:R-HSA-180746|reactome:R-HSA-9615933|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:P18754|rcsb pdb:1A12|rcsb pdb:1I2M	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:/gP2xQp6fUffHTXpXvs8eb5YJ209606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P00403	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:NyMmciQe53E935KEZahz8cGPjIM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q7Z6Z7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O14545	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1396921|uniprotkb:B4DI89|uniprotkb:A8K5L6|intact:EBI-28969419|ensembl:ENSP00000257604|ensembl:ENSP00000396526	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:trad1_human(display_long)|uniprotkb:TRAFD1(gene name)|psi-mi:TRAFD1(display_short)|uniprotkb:FLN29(gene name synonym)|uniprotkb:Protein FLN29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSP00000257604|ensembl:ENSP00000396526|ensembl:ENST00000552890|ensembl:ENSP00000447340|refseq:NP_001137378.1|refseq:NP_006691.1|ensembl:ENSG00000135148(gene)|ensembl:ENST00000257604(transcript)|ensembl:ENST00000412615(transcript)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2D9K	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:hDY19qxNvWdsjDOoUEpuYfe0cdA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8IXI1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BVQ7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-7950854|uniprotkb:Q9HA41|intact:MINT-4718214|uniprotkb:Q9H8W7|uniprotkb:C9JHR5|ensembl:ENSP00000305494	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:spa5l_human(display_long)|uniprotkb:SPATA5L1(gene name)|psi-mi:SPATA5L1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_076968.2|refseq:NP_001310569.1|ensembl:ENSG00000171763(gene)|ensembl:ENST00000305560(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|mint:Q9BVQ7	-	-	comment:mint|comment:homomint	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:8FTQdkGYS4xx3pmJDk9xNtPy3Ao9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NX04	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-8643161|intact:MINT-8163333|uniprotkb:Q8WVD1|uniprotkb:D3DPT1|ensembl:ENSP00000350704|ensembl:ENSP00000476779|ensembl:ENSP00000477159	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ca109_human(display_long)|uniprotkb:C1orf109(gene name)|psi-mi:C1orf109(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001289959.1|refseq:NP_001289960.1|refseq:NP_060320.1|refseq:XP_016857035.1|refseq:XP_016857036.1|refseq:XP_016857040.1|refseq:XP_016857041.1|refseq:XP_016857042.1|refseq:XP_016857043.1|refseq:XP_016857044.1|refseq:XP_016857045.1|ensembl:ENSG00000116922(gene)|ensembl:ENST00000358011(transcript)|ensembl:ENST00000464085(transcript)|ensembl:ENST00000486637(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR029159	-	-	comment:mint	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:y5dE6g7YyJ51upo8IJjYBuXE1FE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96C12	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6425121|ensembl:ENSP00000268314|ensembl:ENSP00000456877|uniprotkb:Q86WM9|uniprotkb:Q9H925|uniprotkb:Q9H7P8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:armc5_human(display_long)|uniprotkb:ARMC5(gene name)|psi-mi:ARMC5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000140691(gene)|ensembl:ENST00000268314(transcript)|ensembl:ENST00000563544(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016020"(membrane)|go:"GO:0035801"(adrenal cortex development)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0051607"(defense response to virus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000225(Armadillo)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001288749.1|refseq:NP_001275696.1|refseq:NP_001098717.1|refseq:NP_079018.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ZmP+cRk6jHF3CzosogoO2kQOnF89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6NSI4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-8634209|ensembl:ENSP00000361628|uniprotkb:Q9H7W5|uniprotkb:Q6PHY5|uniprotkb:Q6PII9|intact:MINT-8162145|uniprotkb:Q9NWA6|uniprotkb:Q5JQS1|uniprotkb:Q4G0L7|uniprotkb:H7BY89|uniprotkb:Q5JRF9|uniprotkb:Q6PJU8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:radx_human(display_long)|uniprotkb:RADX(gene name)|psi-mi:RADX(display_short)|uniprotkb:CXorf57(gene name synonym)|uniprotkb:RPA-related and RAD51-antagonist, X-chromosome(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000147231(gene)|ensembl:ENST00000372548(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005657"(replication fork)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040893|refseq:NP_060485.4|refseq:NP_001171711.1	-	-	comment:mint	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:pUlTaH5Wq19LDuJp7qGlWFpa0q09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NWW5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6165897|ensembl:ENSP00000249806|uniprotkb:B4DDH6|uniprotkb:A8K560|uniprotkb:Q6IAB1|uniprotkb:Q96SR0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cln6_human(display_long)|uniprotkb:CLN6(gene name)|psi-mi:CLN6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000128973(gene)|ensembl:ENST00000249806(transcript)|go:"GO:0001573"(ganglioside metabolic process)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007601"(visual perception)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044265"(cellular macromolecule catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0120146"(sulfatide binding)|interpro:IPR029255|refseq:NP_060352.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:oX9lqo/LjQbBWTpBj1voRRmnOO89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96JG9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-12503573|ensembl:ENSP00000402343	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:zn469_human(display_long)|uniprotkb:ZNF469(gene name)|psi-mi:ZNF469(display_short)|uniprotkb:KIAA1858(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSP00000402343|ensembl:ENSG00000225614(gene)|ensembl:ENST00000437464(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039270	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:RZul/Dcgi7frhxVRsAgyedUPZyo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q04917	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8TAF3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P22314	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P29597	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P04350	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BVA1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P49815	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-396587|uniprotkb:O75275|uniprotkb:Q8TAZ1|uniprotkb:A7E2E2|uniprotkb:B4DIQ7|uniprotkb:B4DRN2|uniprotkb:Q4LE71|uniprotkb:C9J378|ensembl:ENSP00000219476|uniprotkb:B4DIL8|uniprotkb:B7Z2B8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tsc2_human(display_long)|uniprotkb:TSC2(gene name)|psi-mi:TSC2(display_short)|uniprotkb:Tuberous sclerosis 2 protein(gene name synonym)|uniprotkb:TSC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000539.2|refseq:NP_001070651.1|refseq:NP_001107854.1|ensembl:ENSG00000103197(gene)|ensembl:ENST00000219476(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006897"(endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|refseq:NP_001305756.1|refseq:NP_001305758.1|refseq:NP_001305760.1|refseq:NP_001305761.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043276"(anoikis)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:1901525"(negative regulation of mitophagy)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018515|interpro:IPR024584|interpro:IPR027107|interpro:IPR035974|mint:P49815|rcsb pdb:7DL2|reactome:R-HSA-1632852|reactome:R-HSA-165181|reactome:R-HSA-198323|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-8854214|refseq:XP_005255586.2|refseq:XP_016879105.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:II0K3oybyrXfM4GEYMwV2ZyoWwE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q99595	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-727290|uniprotkb:Q9BWF5|uniprotkb:B2RDM5|ensembl:ENSP00000356256	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ti17a_human(display_long)|uniprotkb:Inner membrane preprotein translocase Tim17a(gene name synonym)|uniprotkb:TIMM17A(gene name)|psi-mi:TIMM17A(display_short)|uniprotkb:MIMT17(gene name synonym)|uniprotkb:TIM17(gene name synonym)|uniprotkb:TIM17A(gene name synonym)|uniprotkb:TIMM17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006326.1|ensembl:ENSG00000134375(gene)|ensembl:ENST00000367287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:fHf+KQjrFx8eyY+3EH8nVmBq8KE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WVM0	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2615570|uniprotkb:Q9Y384|uniprotkb:Q05DR0|ensembl:ENSP00000356134	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tfb1m_human(display_long)|uniprotkb:"S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1"(gene name synonym)|uniprotkb:Mitochondrial 12S rRNA dimethylase 1(gene name synonym)|uniprotkb:Mitochondrial transcription factor B1(gene name synonym)|uniprotkb:CGI-75(orf name)|uniprotkb:TFB1M(gene name)|psi-mi:TFB1M(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_057104.2|ensembl:ENSG00000029639(gene)|ensembl:ENST00000367166(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0031167"(rRNA methylation)|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR023165|interpro:IPR029063|rcsb pdb:6AAX|rcsb pdb:6AJK|reactome:R-HSA-2151201|reactome:R-HSA-6793080	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:aw07ohZ/7xuqVv7NvbMOqCTMayM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y4P3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2513719|ensembl:ENSP00000307260|uniprotkb:Q9UQE2	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbl2_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)|uniprotkb:WBSCR13(gene name synonym)|uniprotkb:WS beta-transducin repeats protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 13 protein(gene name synonym)|uniprotkb:UNQ563/PRO1125(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000106638(gene)|ensembl:ENST00000305632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410|mint:Q9Y4P3|refseq:NP_036585.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:K0mFwM08LEIAWO/zg4Irplaq9oM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P26639	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1042683|uniprotkb:Q96FP5|uniprotkb:Q9BWA6|uniprotkb:A8K8I1|ensembl:ENSP00000265112|ensembl:ENSP00000424387|uniprotkb:B4DEG8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sytc_human(display_long)|uniprotkb:TARS1(gene name)|psi-mi:TARS1(display_short)|uniprotkb:TARS(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_689508.3|refseq:NP_001245367.1|rcsb pdb:4HWT|rcsb pdb:4P3N|rcsb pdb:4TTV|rcsb pdb:5XLN|reactome:R-HSA-379716|refseq:NP_001245366.1|go:"GO:0005829"(cytosol)|go:"GO:0006435"(threonyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensembl:ENSG00000113407(gene)|interpro:IPR012676(TGS-like)|ensembl:ENST00000265112(transcript)|ensembl:ENST00000502553(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004829"(threonine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|mint:P26639|rcsb pdb:1WWT	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Z+rOaI1ZO1TQftfkRn1HhXUqDAk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P08240	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-726981|ensembl:ENSP00000328023|uniprotkb:Q9BVJ4|uniprotkb:A6NIB3|uniprotkb:B2R5Z8|uniprotkb:B4E0H3|uniprotkb:E9PJS4	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:srpra_human(display_long)|uniprotkb:SRPRA(gene name)|psi-mi:SRPRA(display_short)|uniprotkb:Docking protein alpha(gene name synonym)|uniprotkb:SRPR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	rcsb pdb:2FH5|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|rcsb pdb:2GO5|go:"GO:0045047"(protein targeting to ER)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|rcsb pdb:5L3Q|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101|mint:P08240|rcsb pdb:6Y32|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|ensembl:ENSG00000182934(gene)|ensembl:ENST00000332118(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|refseq:NP_001171313.1|refseq:NP_003130.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4ag/lxPfDGSDWhpnuwQynTvCpuU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8NB90	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-3184062|ensembl:ENSP00000274008|uniprotkb:Q8NI20|uniprotkb:Q86XW1|uniprotkb:Q8TDL7|uniprotkb:C9JT97	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:afg2h_human(display_long)|uniprotkb:SPATA5(gene name)|psi-mi:SPATA5(display_short)|uniprotkb:AFG2(gene name synonym)|uniprotkb:SPAF(gene name synonym)|uniprotkb:Spermatogenesis-associated factor protein(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000145375(gene)|ensembl:ENST00000274008(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0030154"(cell differentiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR041569|refseq:XP_011529981.1|refseq:NP_660208.2|refseq:NP_001304728.1|ensembl:ENSP00000274008	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:qhbyFN2ulm2KC2F2A2lwd1ec7RA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P53814	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1199956|intact:EBI-1199983|uniprotkb:Q8N4H8|uniprotkb:Q8WWW1|uniprotkb:Q8WWW2|uniprotkb:O00569|uniprotkb:O95769|uniprotkb:O95937|uniprotkb:Q9P1S8|uniprotkb:Q9UIT1|uniprotkb:Q9UIT2|ensembl:ENSP00000328635	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:smtn_human(display_long)|uniprotkb:SMTN(gene name)|psi-mi:SMTN(display_short)|uniprotkb:SMSMO(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000183963(gene)|ensembl:ENST00000347557(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:P53814|rcsb pdb:2D87|refseq:NP_001193946.1|refseq:NP_001193947.1|refseq:NP_008863.3|refseq:NP_599031.1|refseq:NP_599032.2|ensembl:ENST00000333137|ensembl:ENSP00000329532|ensembl:ENSP00000328635|ensembl:ENST00000358743|ensembl:ENSP00000351593	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:na+f9ZixP42TZZ0uD5P5tzaroFA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96K37	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-720094|uniprotkb:Q8NBQ2|uniprotkb:Q96JV7|ensembl:ENSP00000470652	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:s35e1_human(display_long)|uniprotkb:SLC35E1(gene name)|psi-mi:SLC35E1(display_short)|uniprotkb:PSEC0038(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_079157.3|ensembl:ENSG00000127526(gene)|ensembl:ENST00000595753(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004853(Protein of unknown function DUF250)|go:"GO:0015297"(antiporter activity)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:UelDuXaGT2mBsXghGzSX5aKisj89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P12236	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P05543	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-12503571|ensembl:ENSP00000329374|ensembl:ENSP00000361644|uniprotkb:D3DUX1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:thbg_human(display_long)|uniprotkb:SERPINA7(gene name)|psi-mi:SERPINA7(display_short)|uniprotkb:Serpin A7(gene name synonym)|uniprotkb:T4-binding globulin(gene name synonym)|uniprotkb:TBG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000123561(gene)|ensembl:ENST00000327674(transcript)|ensembl:ENST00000372563(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:2CEO|rcsb pdb:2RIV|rcsb pdb:2RIW|rcsb pdb:2XN3|rcsb pdb:2XN5|rcsb pdb:2XN6|rcsb pdb:2XN7|rcsb pdb:4X30|rcsb pdb:4YIA|refseq:NP_000345.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:rZAOFLhAUR9kGmhx+0YB1a0z+Ug9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BRK5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1389808|uniprotkb:Q8NBQ3|uniprotkb:Q9NZP7|uniprotkb:B1AME5|uniprotkb:B2RDF1|uniprotkb:B4DSM1|uniprotkb:Q53G52|uniprotkb:Q53HQ9|uniprotkb:Q96AA1|uniprotkb:Q9UN53|intact:EBI-2511482|uniprotkb:B1AME6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cab45_human(display_long)|uniprotkb:Stromal cell-derived factor 4(gene name synonym)|uniprotkb:SDF4(gene name)|psi-mi:SDF4(display_short)|uniprotkb:CAB45(gene name synonym)|uniprotkb:PSEC0034(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_057631.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_011539858.1|interpro:IPR027240|mint:Q9BRK5|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0021549"(cerebellum development)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070625"(zymogen granule exocytosis)|go:"GO:0099558"(maintenance of synapse structure)|refseq:NP_057260.3	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:wQ0Ov1MDf6p0BmUCZRAS+Na/ERc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P31431	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-3913237|uniprotkb:Q16833|uniprotkb:O00773|uniprotkb:Q53FN9|uniprotkb:Q6FGN3|ensembl:ENSP00000361818	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sdc4_human(display_long)|uniprotkb:SDC4(gene name)|psi-mi:SDC4(display_short)|uniprotkb:Amphiglycan(gene name synonym)|uniprotkb:Ryudocan core protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002990.2|ensembl:ENSG00000124145(gene)|ensembl:ENST00000372733(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016477"(cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|rcsb pdb:1EJP|rcsb pdb:1EJQ|rcsb pdb:1OBY|rcsb pdb:1YBO|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|dip:DIP-29945N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ggGFQ0PE+rGXSk3dHtQCgHwSjjk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P34741	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1172957|uniprotkb:Q9H6V1|uniprotkb:B3KQA3|ensembl:ENSP00000307046|uniprotkb:Q6PIS6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sdc2_human(display_long)|uniprotkb:SDC2(gene name)|psi-mi:SDC2(display_short)|uniprotkb:HSPG1(gene name synonym)|uniprotkb:Fibroglycan(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan core protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002989.2|reactome:R-HSA-975634|reactome:R-HSA-8957275|ensembl:ENSG00000169439(gene)|ensembl:ENST00000302190(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031201|mint:P34741|rcsb pdb:6ITH|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-381426|reactome:R-HSA-3928662|reactome:R-HSA-4420332|dip:DIP-29943N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:dUYGfiWzMHbYLZdV/ibV6RmeYUA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P49591	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1053431|uniprotkb:Q5T5C8|uniprotkb:Q9NSE3|uniprotkb:B2R6Y9|ensembl:ENSP00000234677	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sysc_human(display_long)|uniprotkb:SARS1(gene name)|psi-mi:SARS1(display_short)|uniprotkb:SARS(gene name synonym)|uniprotkb:SERS(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006504.2|ensembl:ENSG00000031698(gene)|ensembl:ENST00000234677(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR033729|interpro:IPR042103|rcsb pdb:3VBB|rcsb pdb:4L87|rcsb pdb:4RQE|rcsb pdb:4RQF|reactome:R-HSA-2408557|reactome:R-HSA-379716|dip:DIP-38215N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4+Ai/MIybmiKJyfa0C0bhnW/CG49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NZ71	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2859587|uniprotkb:A2A398|uniprotkb:A2A397|uniprotkb:Q9NZ73|uniprotkb:Q9H4X6|uniprotkb:Q9BW37|uniprotkb:Q9NX25|uniprotkb:B4DYM3|uniprotkb:Q9H402|uniprotkb:Q9UPR4|uniprotkb:B4DRM5|uniprotkb:B4E3N6|uniprotkb:Q9Y4R6|uniprotkb:Q5JTV4|intact:EBI-3248693|uniprotkb:Q5JTV3|uniprotkb:E1P5J4|uniprotkb:E1P5J5|ensembl:ENSP00000359035|intact:EBI-28972964	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rtel1_human(display_long)|uniprotkb:RTEL1(gene name)|psi-mi:RTEL1(display_short)|uniprotkb:C20orf41(gene name synonym)|uniprotkb:KIAA1088(gene name synonym)|uniprotkb:NHL(gene name synonym)|uniprotkb:Novel helicase-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001269938.1|refseq:NP_001269939.1|ensembl:ENST00000318100|ensembl:ENSP00000322287|ensembl:ENST00000360203|ensembl:ENSP00000353332|ensembl:ENSP00000359035|ensembl:ENST00000482936|ensembl:ENSP00000457868|ensembl:ENST00000508582|ensembl:ENSP00000424307|refseq:NP_057518.1|refseq:NP_116575.3|ensembl:ENSG00000258366(gene)|ensembl:ENST00000370018(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000732"(strand displacement)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0031297"(replication fork processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1904506"(negative regulation of telomere maintenance in response to DNA damage)|go:"GO:1904535"(positive regulation of telomeric loop disassembly)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR030845|reactome:R-HSA-171319|reactome:R-HSA-2564830|reactome:R-HSA-5693554	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6gjiNtZ3d+GnlnJR++7G7yo53fs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q71UM5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P42677	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P05387	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P05386	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8NHW5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355416	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rla0l_human(display_long)|uniprotkb:RPLP0P6(gene name)|psi-mi:RPLP0P6(display_short)|uniprotkb:Large ribosomal subunit protein uL10-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	interpro:IPR001790(Ribosomal protein L10)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR040637|interpro:IPR030670|interpro:IPR043141|interpro:IPR043164	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:mwr/+G18VKkJ2yrEjIMbz9m058o9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P62877	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96QR8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2880222|ensembl:ENSP00000379051|uniprotkb:A4D2L7	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:purb_human(display_long)|uniprotkb:PURB(gene name)|psi-mi:PURB(display_short)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000146676(gene)|ensembl:ENST00000395699(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|mint:Q96QR8|go:"GO:0046332"(SMAD binding)|refseq:NP_150093.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:C29M3TyoXYI3mhCdaSsYC2kt8ek9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q15185	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1049387|uniprotkb:Q8WU70|intact:EBI-9357271|uniprotkb:B4DHP2|uniprotkb:B4DP11|uniprotkb:B4DP21|uniprotkb:A8K7D0|ensembl:ENSP00000262033	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tebp_human(display_long)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:PTGES3(gene name)|psi-mi:PTGES3(display_short)|uniprotkb:P23(gene name synonym)|uniprotkb:TEBP(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001269530.1|refseq:NP_001269531.1|refseq:NP_001269532.1|refseq:NP_001269533.1|refseq:NP_001269534.1|refseq:NP_006592.3|dip:DIP-279N|ensembl:ENSG00000110958(gene)|ensembl:ENST00000262033(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043588"(skin development)|go:"GO:0050220"(prostaglandin-E synthase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060430"(lung saccule development)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|mint:Q15185|rcsb pdb:1EJF|reactome:R-HSA-2162123|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|rcsb pdb:1LG0	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6NuM7BPG39XzwqdKBCr74uuumCo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q2VWP7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-12503569|ensembl:ENSP00000373937|uniprotkb:Q8N7D8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:prtg_human(display_long)|uniprotkb:PRTG(gene name)|psi-mi:PRTG(display_short)|uniprotkb:Protein Shen-Dan(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000166450(gene)|mint:Q2VWP7|ensembl:ENST00000389286(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0050768"(negative regulation of neurogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|refseq:NP_776175.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:BOC37mZ/S6SJUnCNslUTCorzQ5g9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P41743	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-286199|uniprotkb:Q8WW06|uniprotkb:D3DNQ4|ensembl:ENSP00000295797	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kpci_human(display_long)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:PRKCI(gene name)|psi-mi:PRKCI(display_short)|uniprotkb:DXS1179E(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002731.4|dip:DIP-31311N|ensembl:ENSG00000163558(gene)|ensembl:ENST00000295797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0046903"(secretion)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:P41743|rcsb pdb:1VD2|rcsb pdb:1WMH|rcsb pdb:1ZRZ|rcsb pdb:3A8W|rcsb pdb:3A8X|rcsb pdb:3ZH8|rcsb pdb:5LI1|rcsb pdb:5LI9|rcsb pdb:5LIH|rcsb pdb:6ILZ|reactome:R-HSA-1912408|reactome:R-HSA-209543|reactome:R-HSA-420029	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:v8sZdKjtlBejk0MH/9gwOjRqy+49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P24723	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2865850|uniprotkb:Q8NE03|uniprotkb:Q16246|uniprotkb:B4DJN5	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kpcl_human(display_long)|uniprotkb:PRKCH(gene name)|psi-mi:PRKCH(display_short)|uniprotkb:PKCL(gene name synonym)|uniprotkb:PRKCL(gene name synonym)|uniprotkb:PKC-L(gene name synonym)|uniprotkb:nPKC-eta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0005911"(cell-cell junction)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0070528"(protein kinase C signaling)|ensembl:ENST00000332981|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0030168"(platelet activation)|refseq:NP_006246.2|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR020454|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:2FK9|ensembl:ENSP00000450981|ensembl:ENST00000555082|reactome:R-HSA-114508|reactome:R-HSA-418597|go:"GO:0070062"(extracellular exosome)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|rcsb pdb:3TXO|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0007165"(signal transduction)|interpro:IPR027431|ensembl:ENSG00000027075|ensembl:ENSP00000329127|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0017160"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR034665|refseq:XP_016876947.1|dip:DIP-44588N|mint:MINT-3973608|go:"GO:0004674"(protein serine/threonine kinase activity)|interpro:IPR035892|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:wqrydF3n2dujiiKKk44XmuQSuJk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q05655	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-704279|uniprotkb:B2R834|uniprotkb:Q86XJ6|uniprotkb:Q15144|uniprotkb:B0KZ81|ensembl:ENSP00000331602|ensembl:ENSP00000378217|ensembl:ENSP00000498400|ensembl:ENSP00000498623|ensembl:ENSP00000499558	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kpcd_human(display_long)|uniprotkb:nPKC-delta(gene name synonym)|uniprotkb:PRKCD(gene name)|psi-mi:PRKCD(display_short)|uniprotkb:Tyrosine-protein kinase PRKCD(gene name synonym)|uniprotkb:PKCD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006245.2|refseq:NP_997704.1|refseq:NP_001303256.1|refseq:XP_016862344.1|refseq:XP_016862345.1|refseq:XP_006713322.1|dip:DIP-29954N|ensembl:ENSG00000163932(gene)|ensembl:ENST00000330452(transcript)|ensembl:ENST00000394729(transcript)|ensembl:ENST00000650739(transcript)|ensembl:ENST00000652449(transcript)|ensembl:ENST00000654719(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036019"(endolysosome)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900163"(positive regulation of phospholipid scramblase activity)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:2000303"(regulation of ceramide biosynthetic process)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|go:"GO:2000753"(positive regulation of glucosylceramide catabolic process)|go:"GO:2000755"(positive regulation of sphingomyelin catabolic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027436|interpro:IPR034667|interpro:IPR035892|mint:Q05655|rcsb pdb:1YRK|reactome:R-HSA-111465|reactome:R-HSA-111933|reactome:R-HSA-114508|reactome:R-HSA-1250196|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-418597|reactome:R-HSA-450520|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8932339|rcsb pdb:2YUU	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:BR/lNGg6f55rGP91akTf8BLkX449606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NW08	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2515106|uniprotkb:A8K6H0|uniprotkb:Q9NW59|uniprotkb:B3KV73|uniprotkb:F5H1E6|ensembl:ENSP00000228347	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rpc2_human(display_long)|uniprotkb:POLR3B(gene name)|psi-mi:POLR3B(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit B(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III 127.6 kDa polypeptide(gene name synonym)|uniprotkb:C128(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060552.4|refseq:NP_001154180.1|ensembl:ENSG00000013503(gene)|ensembl:ENST00000228347(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|mint:Q9NW08|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:wHQRBDeUbMtfpXmUd/LkiE6GNaM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P27986	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6NSJ2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6148204|uniprotkb:Q8N7Z4|ensembl:ENSP00000292140	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:phlb3_human(display_long)|uniprotkb:PHLDB3(gene name)|psi-mi:PHLDB3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_942147.3|ensembl:ENSG00000176531(gene)|ensembl:ENST00000292140(transcript)|go:"GO:0019899"(enzyme binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:mHR2QwOa65vWru5ZUAnRSjMU8lU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8N7H5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P13674	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1237386|uniprotkb:Q15082|uniprotkb:Q15083|uniprotkb:Q5VSQ5|uniprotkb:C9JL12|ensembl:ENSP00000307318|ensembl:ENSP00000378353	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:p4ha1_human(display_long)|uniprotkb:P4HA1(gene name)|psi-mi:P4HA1(display_short)|uniprotkb:P4HA(gene name synonym)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000908.2|refseq:NP_001017962.1|refseq:NP_001136067.1|refseq:NP_001136068.1|dip:DIP-38180N|ensembl:ENSG00000122884(gene)|ensembl:ENST00000307116(transcript)|ensembl:ENST00000394890(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:P13674|rcsb pdb:1TJC|rcsb pdb:2V5F|rcsb pdb:2YQ8|rcsb pdb:4BT8|rcsb pdb:4BT9|rcsb pdb:4BTA|rcsb pdb:4BTB|reactome:R-HSA-1650814|go:"GO:0043231"(intracellular membrane-bounded organelle)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Yo9hgWVJ5iUGITVWKfvjhTNX1lk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P35240	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6N069	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2561139|ensembl:ENSP00000368716|uniprotkb:Q5VSP9|uniprotkb:Q8N5J3|uniprotkb:Q6P2D5|uniprotkb:Q8N870|uniprotkb:B0QZ59	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:naa16_human(display_long)|uniprotkb:NARG1L(gene name synonym)|uniprotkb:NMDA receptor-regulated 1-like protein(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:NAA16(gene name)|psi-mi:NAA16(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000172766(gene)|ensembl:ENST00000379406(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR021183|mint:Q6N069|refseq:NP_001104268.1|refseq:NP_060997.2|refseq:NP_078837.3|refseq:XP_011533530.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:y23dxDxweBtEeb8mEsJ4bgD6N+Q9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NVV4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2556166|uniprotkb:Q659E3|uniprotkb:Q9HA74|uniprotkb:Q6P7E5|uniprotkb:D3DRX0|ensembl:ENSP00000263063	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:papd1_human(display_long)|uniprotkb:PAPD1(gene name synonym)|uniprotkb:mtPAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase(gene name synonym)|uniprotkb:PAP-associated domain-containing protein 1(gene name synonym)|uniprotkb:Terminal uridylyltransferase 1(gene name synonym)|uniprotkb:MTPAP(gene name)|psi-mi:MTPAP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060579.3|ensembl:ENSG00000107951(gene)|ensembl:ENST00000263063(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002134"(UTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR041252|interpro:IPR043519|rcsb pdb:3PQ1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:KUNsYSjhCHVHD8WnZbw5V60Wlec9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96GC5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-5325315|ensembl:ENSP00000308717|uniprotkb:Q49AK7|uniprotkb:Q4U2Q4|uniprotkb:Q9P091|uniprotkb:Q9Y5J0|intact:EBI-10967301|uniprotkb:B4DN34	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rm48_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL48(gene name synonym)|uniprotkb:CGI-118(orf name)|uniprotkb:HSPC290(orf name)|uniprotkb:MRPL48(gene name)|psi-mi:MRPL48(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000175581(gene)|ensembl:ENST00000310614(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR027486|interpro:IPR027487|mint:Q96GC5|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|interpro:IPR036838|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:6ZSG|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF6|refseq:NP_001305427.1|refseq:NP_001305428.1|refseq:NP_001305429.1|refseq:NP_057139.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:xCdGuctoVF3DrDHZedpDi+IOxxQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5JRA6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2291868|uniprotkb:A8K2S0|uniprotkb:A8MT05|uniprotkb:A8MT13|uniprotkb:B7Z430|uniprotkb:Q3S4X3|uniprotkb:Q5JRB0|uniprotkb:Q14083|uniprotkb:Q5JRA5|uniprotkb:Q5JRB1|uniprotkb:Q5JRB2|uniprotkb:Q6UVY8|uniprotkb:Q86Y60|uniprotkb:Q8N8M5|uniprotkb:Q92580|intact:EBI-2803073|ensembl:ENSP00000340900	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tgo1_human(display_long)|uniprotkb:TANGO(gene name synonym)|uniprotkb:MIA3(gene name)|psi-mi:MIA3(display_short)|uniprotkb:KIAA0268(gene name synonym)|uniprotkb:C219-reactive peptide(gene name synonym)|uniprotkb:D320(gene name synonym)|uniprotkb:UNQ6077/PRO20088(orf name)|uniprotkb:Melanoma inhibitory activity protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_940953.2|refseq:NP_001287796.1|ensembl:ENSG00000154305(gene)|ensembl:ENST00000344922(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|refseq:NP_001310992.1|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:2000402"(negative regulation of lymphocyte migration)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:DGy7mQTlQIbcaklbpG7jmdj9G/I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P50579	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2214155|uniprotkb:B2RDI8|uniprotkb:B4DUX5|uniprotkb:G3XA91|uniprotkb:Q8NB11|ensembl:ENSP00000325312	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:map2_human(display_long)|uniprotkb:METAP2(gene name)|psi-mi:METAP2(display_short)|uniprotkb:MNPEP(gene name synonym)|uniprotkb:P67EIF2(gene name synonym)|uniprotkb:Initiation factor 2-associated 67 kDa glycoprotein(gene name synonym)|uniprotkb:Peptidase M(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001304111.1|refseq:NP_001304112.1|refseq:NP_006829.1|refseq:NP_001317175.1|ensembl:ENSG00000111142(gene)|ensembl:ENST00000323666(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0016485"(protein processing)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR002468(Peptidase M24A, methionine aminopeptidase, subfamily 2)|interpro:IPR018349|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:P50579|rcsb pdb:1B59|rcsb pdb:1B6A|rcsb pdb:1BN5|rcsb pdb:1BOA|rcsb pdb:1KQ0|rcsb pdb:1QZY|rcsb pdb:1R58|rcsb pdb:1R5G|rcsb pdb:1R5H|rcsb pdb:1YW7|rcsb pdb:1YW8|rcsb pdb:1YW9|rcsb pdb:2ADU|rcsb pdb:2EA2|rcsb pdb:2EA4|rcsb pdb:2GA2|rcsb pdb:2OAZ|rcsb pdb:5CLS|rcsb pdb:5D6E|rcsb pdb:5D6F|rcsb pdb:5JFR|rcsb pdb:5JHU|rcsb pdb:5JI6|rcsb pdb:5LYW|rcsb pdb:5LYX|rcsb pdb:6QED|rcsb pdb:6QEF|rcsb pdb:6QEG|rcsb pdb:6QEH|rcsb pdb:6QEI|rcsb pdb:6QEJ|rcsb pdb:7A12|rcsb pdb:7A13|rcsb pdb:7A14|rcsb pdb:7A15|rcsb pdb:7A16|reactome:R-HSA-2514859|rcsb pdb:1KQ9	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:I2hlcoKItAl5cLljV3qaAFtFcxY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NU22	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WXG6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-310528|uniprotkb:O15293|intact:EBI-728168|uniprotkb:D3DQR4|uniprotkb:Q15732|uniprotkb:Q15741|uniprotkb:Q8IWD7|uniprotkb:Q8WXG3|uniprotkb:Q8WXG4|uniprotkb:Q8WXG5|uniprotkb:Q8WZ63|uniprotkb:O15065|uniprotkb:A8K8S7|uniprotkb:B5MEE5|ensembl:ENSP00000310933	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:madd_human(display_long)|uniprotkb:MADD(gene name)|psi-mi:MADD(display_short)|uniprotkb:DENN(gene name synonym)|uniprotkb:IG20(gene name synonym)|uniprotkb:KIAA0358(gene name synonym)|uniprotkb:Differentially expressed in normal and neoplastic cells(gene name synonym)|uniprotkb:Insulinoma glucagonoma clone 20(gene name synonym)|uniprotkb:Rab3 GDP/GTP exchange factor(gene name synonym)|uniprotkb:Rab3 GDP/GTP exchange protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001129415.1|refseq:NP_001129416.1|refseq:NP_003673.3|refseq:NP_569826.2|refseq:NP_569827.2|refseq:NP_569828.2|refseq:NP_569829.2|refseq:NP_569830.2|refseq:NP_569831.1|refseq:NP_569832.2|refseq:XP_005253246.1|refseq:XP_005253253.1|refseq:XP_005253258.1|refseq:XP_005253260.1|refseq:XP_005253256.1|refseq:XP_005253261.1|refseq:XP_005253262.1|ensembl:ENSP00000310933|ensembl:ENST00000349238|ensembl:ENSP00000304505|ensembl:ENST00000395336|ensembl:ENSP00000378745|ensembl:ENST00000395344|ensembl:ENSP00000378753|ensembl:ENST00000402192|ensembl:ENSP00000384287|ensembl:ENST00000402799|ensembl:ENSP00000385585|ensembl:ENST00000406482|ensembl:ENSP00000384435|ensembl:ENST00000407859|ensembl:ENSP00000384204|ensembl:ENSG00000110514(gene)|ensembl:ENST00000311027(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030424"(axon)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR037516|interpro:IPR039980|interpro:IPR043153|reactome:R-HSA-5357905|reactome:R-HSA-8876198	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:+YF66uj9WWG+hZ6fvrmXfelsQZs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P50851	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1052167|uniprotkb:Q9H2U3|uniprotkb:Q9H2U4|uniprotkb:Q8NFQ0|uniprotkb:Q4W5J4|uniprotkb:Q4W5L6|ensembl:ENSP00000349629	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:lrba_human(display_long)|uniprotkb:CDC4-like protein(gene name synonym)|uniprotkb:Beige-like protein(gene name synonym)|uniprotkb:LRBA(gene name)|psi-mi:LRBA(display_short)|uniprotkb:BGL(gene name synonym)|uniprotkb:CDC4L(gene name synonym)|uniprotkb:LBA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006717.2|refseq:NP_001186211.2|refseq:XP_011530736.1|ensembl:ENSG00000198589(gene)|ensembl:ENST00000357115(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|rcsb pdb:1T77|dip:DIP-50531N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:FSUTaFKy63UUratp7X29LN/f1F49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8IVT5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-486984|uniprotkb:Q13476|uniprotkb:F8WEA9|uniprotkb:H7BYU0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ksr1_human(display_long)|uniprotkb:KSR1(gene name)|psi-mi:KSR1(display_short)|uniprotkb:KSR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055053.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR025561|rcsb pdb:5VYK|rcsb pdb:7JUW|rcsb pdb:7JUX|rcsb pdb:7JUY|rcsb pdb:7JUZ|rcsb pdb:7JV0|rcsb pdb:7JV1|reactome:R-HSA-5673000|reactome:R-HSA-9656223|go:"GO:0004672"(protein kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|reactome:R-HSA-5674135|reactome:R-HSA-5675221|refseq:XP_011523731.1|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|refseq:XP_016880760.1|refseq:XP_016880761.1|refseq:XP_016880762.1|refseq:XP_016880763.1|refseq:XP_016880764.1|refseq:XP_016880765.1|dip:DIP-32619N|reactome:R-HSA-9649948	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:anjemyXOtuiBeBl7b6kwKNdJkUg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q07866	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-721019|uniprotkb:F8VTM4|uniprotkb:Q7RTQ3|uniprotkb:Q86V77|uniprotkb:Q86V78|uniprotkb:Q86V79|uniprotkb:Q7RTM2|uniprotkb:Q7RTM3|uniprotkb:Q7RTM5|uniprotkb:Q7RTP9|uniprotkb:Q7RTQ5|uniprotkb:Q7RTQ6|uniprotkb:Q86SF5|uniprotkb:Q86TF5|uniprotkb:Q86V74|uniprotkb:Q86V75|uniprotkb:Q86V76|uniprotkb:Q96H62|uniprotkb:A6NF62|intact:EBI-28976313|ensembl:ENSP00000341154	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:klc1_human(display_long)|uniprotkb:KLC1(gene name)|psi-mi:KLC1(display_short)|uniprotkb:KLC(gene name synonym)|uniprotkb:KNS2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001123579.1|refseq:NP_005543.2|refseq:NP_891553.2|ensembl:ENST00000452929|ensembl:ENSP00000414982|ensembl:ENST00000553286|ensembl:ENSP00000452487|ensembl:ENST00000246489|ensembl:ENSP00000246489|ensembl:ENST00000334553|ensembl:ENST00000554228|ensembl:ENSP00000450616|ensembl:ENST00000557450|ensembl:ENSP00000450648|ensembl:ENST00000634686|ensembl:ENSP00000488938|ensembl:ENSP00000334523|ensembl:ENST00000347839|ensembl:ENSP00000334618|ensembl:ENSP00000341154|ensembl:ENST00000389744|ensembl:ENSP00000374394|dip:DIP-40371N|ensembl:ENSG00000126214(gene)|ensembl:ENST00000348520(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035617"(stress granule disassembly)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q07866|rcsb pdb:3NF1|rcsb pdb:5OJ8|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0030426"(growth cone)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:T7SJbB/PScRqj74O/NH4q1KU0YM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q63ZY3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2556193|uniprotkb:Q9H8S4|uniprotkb:Q6GUF5|uniprotkb:Q9NUP0|uniprotkb:Q3KQZ3|uniprotkb:B0I1P4|uniprotkb:Q9P210|ensembl:ENSP00000465650	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kank2_human(display_long)|uniprotkb:ANKRD25(gene name synonym)|uniprotkb:KIAA1518(gene name synonym)|uniprotkb:MXRA3(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 25(gene name synonym)|uniprotkb:SRC-1-interacting protein(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 3(gene name synonym)|uniprotkb:KANK2(gene name)|psi-mi:KANK2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001129663.1|refseq:NP_056308.3|rcsb pdb:6TMD|ensembl:ENSG00000197256(gene)|ensembl:ENST00000586659(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0070563"(negative regulation of vitamin D receptor signaling pathway)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|mint:Q63ZY3|rcsb pdb:4HBD|rcsb pdb:5YBV|refseq:NP_001316380.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:5lZ6UWmx5+N6B1B/xTmVfvxA7Ag9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9HDC5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8N5M9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10266796|uniprotkb:Q8NCF6|uniprotkb:Q96SW1|ensembl:ENSP00000496942	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:jagn1_human(display_long)|uniprotkb:JAGN1(gene name)|psi-mi:JAGN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_115881.3|ensembl:ENSG00000171135(gene)|ensembl:ENST00000647897(transcript)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0038158"(granulocyte colony-stimulating factor signaling pathway)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:1904577"(cellular response to tunicamycin)|go:"GO:1990266"(neutrophil migration)|interpro:IPR009787(Protein of unknown function DUF1352)|rcsb pdb:6WVD	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:QXhwCOcuNxsqCIz2QRhISmENY949606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y6K9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O95757	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	intact:EBI-11820565	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	-	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:1304"(molecule set)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	-	-	-	comment:P0DMV8,P0DMV9	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	-	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q58FG1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6916562	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hs904_human(display_long)|uniprotkb:HSP90AA4P(gene name)|psi-mi:HSP90AA4P(display_short)|uniprotkb:HSP90AD(gene name synonym)|uniprotkb:HSPCAL2(gene name synonym)|uniprotkb:Heat shock 90 kDa protein 1 alpha-like 2(gene name synonym)|uniprotkb:Heat shock protein 90-alpha D(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ikTrrPpUeO74Iq6mjoTSomMVqsg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P07900	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P61978	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BW72	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2867844|ensembl:ENSP00000274787	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hig2a_human(display_long)|uniprotkb:HIGD2A(gene name)|psi-mi:HIGD2A(display_short)|uniprotkb:RCF1 homolog B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_620175.1|ensembl:ENST00000274787(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|ensembl:ENSG00000146066(gene)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:slz4YrTa7zG05TU7zobaVsWuNHg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O43824	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10970033|ensembl:ENSP00000316598|uniprotkb:Q5HYX8|uniprotkb:Q53F77|uniprotkb:H0Y2S1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gtpb6_human(display_long)|uniprotkb:GTPBP6(gene name)|psi-mi:GTPBP6(display_short)|uniprotkb:PGPL(gene name synonym)|uniprotkb:Pseudoautosomal GTP-binding protein-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_036359.3|ensembl:ENSG00000178605(gene)|ensembl:ENST00000326153(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006073(GTP1/OBG)|interpro:IPR016496(GTP-binding protein, HflX)|interpro:IPR025121|interpro:IPR027417|interpro:IPR030394|interpro:IPR032305|interpro:IPR042108|rcsb pdb:7OF2|rcsb pdb:7OF4|rcsb pdb:7OF6	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:NlrtEAFZqVgQqV84Z6unM4jKWI89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75487	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-3050469|uniprotkb:B4E2C0|ensembl:ENSP00000359864|uniprotkb:B2R6J7|uniprotkb:Q9UPD9|uniprotkb:Q96L43|uniprotkb:Q9NU08|uniprotkb:Q6ZMA6|uniprotkb:Q9UJN1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gpc4_human(display_long)|uniprotkb:GPC4(gene name)|psi-mi:GPC4(display_short)|uniprotkb:K-glypican(gene name synonym)|uniprotkb:UNQ474/PRO937(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000076716(gene)|ensembl:ENST00000370828(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|mint:O75487|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1904929"(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001863(Glypican)|interpro:IPR019803|interpro:IPR031180|go:"GO:0016055"(Wnt signaling pathway)|refseq:NP_001439.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6IC3ItqIRoNTmnS+hi/U34DlXN09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P51654	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-5654198|uniprotkb:C9JLE3|uniprotkb:Q2L880|uniprotkb:G3V1R0|uniprotkb:Q2L882|ensembl:ENSP00000359854	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gpc3_human(display_long)|uniprotkb:GTR2-2(gene name synonym)|uniprotkb:Intestinal protein OCI-5(gene name synonym)|uniprotkb:MXR7(gene name synonym)|uniprotkb:OCI5(gene name synonym)|uniprotkb:GPC3(gene name)|psi-mi:GPC3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001158091.1|dip:DIP-61509N|refseq:NP_004475.1|refseq:NP_001158089.1|ensembl:ENSG00000147257(gene)|ensembl:ENST00000370818(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0016477"(cell migration)|go:"GO:0030282"(bone mineralization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060422"(peptidyl-dipeptidase inhibitor activity)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072111"(cell proliferation involved in kidney development)|go:"GO:0072138"(mesenchymal cell proliferation involved in ureteric bud development)|go:"GO:0072180"(mesonephric duct morphogenesis)|go:"GO:0072203"(cell proliferation involved in metanephros development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:2000050"(regulation of non-canonical Wnt signaling pathway)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001863(Glypican)|interpro:IPR015501(Glypican 3)|interpro:IPR019803|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-381426|reactome:R-HSA-4420332|reactome:R-HSA-8957275|reactome:R-HSA-975634	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:+H2PtA0Y61S+2l56UPxwxBpCosc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q92896	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359610|uniprotkb:Q6P9D1|uniprotkb:Q13221|uniprotkb:D3DUJ7|uniprotkb:B7Z8Y4|ensembl:ENSP00000405984	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gslg1_human(display_long)|uniprotkb:GLG1(gene name)|psi-mi:GLG1(display_short)|uniprotkb:CFR1(gene name synonym)|uniprotkb:ESL1(gene name synonym)|uniprotkb:MG160(gene name synonym)|uniprotkb:Golgi sialoglycoprotein MG-160(gene name synonym)|uniprotkb:E-selectin ligand 1(gene name synonym)|uniprotkb:Cysteine-rich fibroblast growth factor receptor(gene name synonym)|uniprotkb:CFR-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001139138.1|refseq:NP_001139139.1|refseq:NP_036333.2|ensembl:ENSG00000090863(gene)|ensembl:ENST00000422840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001893(Cysteine rich repeat)|interpro:IPR017873|interpro:IPR039728|reactome:R-HSA-202733|dip:DIP-27582N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:FTlNQD3o/wkPVjXkbB/G73BoBhw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P04062	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1564609|uniprotkb:B7Z5G2|uniprotkb:B7Z6S1|uniprotkb:J3KQG4|uniprotkb:J3KQK9|uniprotkb:Q16545|uniprotkb:Q4VX22|uniprotkb:Q6I9R6|uniprotkb:Q9UMJ8|uniprotkb:A8K796|ensembl:ENSP00000314508|ensembl:ENSP00000357357	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:glcm_human(display_long)|uniprotkb:Beta-glucocerebrosidase(gene name synonym)|uniprotkb:Acid beta-glucosidase(gene name synonym)|uniprotkb:D-glucosyl-N-acylsphingosine glucohydrolase(gene name synonym)|uniprotkb:Alglucerase(gene name synonym)|uniprotkb:Imiglucerase(gene name synonym)|uniprotkb:GBA(gene name)|psi-mi:GBA(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:GLUC(gene name synonym)|uniprotkb:Cholesterol glucosyltransferase(gene name synonym)|uniprotkb:Cholesteryl-beta-glucosidase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001165282.1|refseq:NP_001165283.1|refseq:NP_000148.2|refseq:NP_001005741.1|refseq:NP_001005742.1|dip:DIP-38645N|ensembl:ENSG00000177628(gene)|ensembl:ENST00000327247(transcript)|ensembl:ENST00000368373(transcript)|go:"GO:0004348"(glucosylceramidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006680"(glucosylceramide catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007040"(lysosome organization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009268"(response to pH)|go:"GO:0014004"(microglia differentiation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0021694"(cerebellar Purkinje cell layer formation)|go:"GO:0021859"(pyramidal neuron differentiation)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030259"(lipid glycosylation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0033574"(response to testosterone)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043627"(response to estrogen)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050295"(steryl-beta-glucosidase activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061744"(motor behavior)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901805"(beta-glucoside catabolic process)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1905037"(autophagosome organization)|go:"GO:1905165"(regulation of lysosomal protein catabolic process)|interpro:IPR001139(Glycoside hydrolase, family 30)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033452|interpro:IPR033453|mint:P04062|rcsb pdb:1OGS|rcsb pdb:1Y7V|rcsb pdb:2F61|rcsb pdb:2J25|rcsb pdb:2NSX|rcsb pdb:2NT0|rcsb pdb:2NT1|rcsb pdb:2V3D|rcsb pdb:2V3E|rcsb pdb:2V3F|rcsb pdb:2VT0|rcsb pdb:2WCG|rcsb pdb:2WKL|rcsb pdb:2XWD|rcsb pdb:2XWE|rcsb pdb:3GXD|rcsb pdb:3GXF|rcsb pdb:3GXI|rcsb pdb:3GXM|rcsb pdb:3KE0|rcsb pdb:3KEH|rcsb pdb:3RIK|rcsb pdb:3RIL|rcsb pdb:5LVX|rcsb pdb:6MOZ|rcsb pdb:6Q1N|rcsb pdb:6Q1P|rcsb pdb:6Q6K|rcsb pdb:6Q6L|rcsb pdb:6Q6N|rcsb pdb:6TJJ|rcsb pdb:6TJK|rcsb pdb:6TJQ|rcsb pdb:6TN1|rcsb pdb:6YTP|rcsb pdb:6YTR|rcsb pdb:6YUT|rcsb pdb:6YV3|rcsb pdb:6Z39|rcsb pdb:6Z3I|reactome:R-HSA-1660662|reactome:R-HSA-390471	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:AWV635bfvuSWV1vflhTcun2riyk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13451	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-306914|ensembl:ENSP00000349811|ensembl:ENSP00000441205|ensembl:ENSP00000444810|uniprotkb:Q5TGM6|uniprotkb:F5H7R1|uniprotkb:Q59EB8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:fkbp5_human(display_long)|uniprotkb:FKBP5(gene name)|psi-mi:FKBP5(display_short)|uniprotkb:AIG6(gene name synonym)|uniprotkb:FKBP51(gene name synonym)|uniprotkb:FK506-binding protein 5(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:54 kDa progesterone receptor-associated immunophilin(gene name synonym)|uniprotkb:FKBP54(gene name synonym)|uniprotkb:FF1 antigen(gene name synonym)|uniprotkb:HSP90-binding immunophilin(gene name synonym)|uniprotkb:Androgen-regulated protein 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000096060(gene)|ensembl:ENST00000357266(transcript)|ensembl:ENST00000536438(transcript)|ensembl:ENST00000539068(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|refseq:NP_001139247.1|refseq:NP_001139248.1|refseq:NP_004108.1|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031210|mint:Q13451|rcsb pdb:1KT0|rcsb pdb:3O5D|rcsb pdb:3O5E|rcsb pdb:3O5F|rcsb pdb:3O5G|rcsb pdb:3O5I|rcsb pdb:3O5J|rcsb pdb:3O5K|rcsb pdb:3O5L|rcsb pdb:3O5M|rcsb pdb:3O5O|rcsb pdb:3O5P|rcsb pdb:3O5Q|rcsb pdb:3O5R|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRK|rcsb pdb:4DRM|rcsb pdb:4DRN|rcsb pdb:4DRO|rcsb pdb:4DRP|rcsb pdb:4DRQ|rcsb pdb:4JFI|rcsb pdb:4JFJ|rcsb pdb:4JFK|rcsb pdb:4JFL|rcsb pdb:4JFM|rcsb pdb:4R0X|rcsb pdb:4TW6|rcsb pdb:4TW7|rcsb pdb:4TX0|rcsb pdb:4W9O|rcsb pdb:4W9P|rcsb pdb:4W9Q|rcsb pdb:5BXJ|rcsb pdb:5DIT|rcsb pdb:5DIU|rcsb pdb:5DIV|rcsb pdb:5NJX|rcsb pdb:5OBK|rcsb pdb:5OMP|rcsb pdb:6SAF|rcsb pdb:6TX4|rcsb pdb:6TX5|rcsb pdb:6TX6|rcsb pdb:6TX7|rcsb pdb:6TX8|rcsb pdb:6TX9|rcsb pdb:6TXX|rcsb pdb:7A6W|rcsb pdb:7A6X|rcsb pdb:7AOT|rcsb pdb:7AOU|rcsb pdb:7AWF|rcsb pdb:7AWX|rcsb pdb:7B9Y|rcsb pdb:7B9Z|rcsb pdb:7BA0|reactome:R-HSA-3371497|reactome:R-HSA-8939211|reactome:R-HSA-9022699|refseq:NP_001139249.1|dip:DIP-27597N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:m2Bnn01E13sovh3BwG71Pgqjdx89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P22830	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1390356|uniprotkb:Q8IXN1|uniprotkb:Q8NAN0|uniprotkb:A8KA72|ensembl:ENSP00000262093	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hemh_human(display_long)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)|uniprotkb:FECH(gene name)|psi-mi:FECH(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000131.2|refseq:NP_001012533.1|dip:DIP-39632N|ensembl:ENSG00000066926(gene)|ensembl:ENST00000262093(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010288"(response to lead ion)|go:"GO:0017085"(response to insecticide)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051597"(response to methylmercury)|go:"GO:0070541"(response to platinum ion)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1HRK|rcsb pdb:2HRC|rcsb pdb:2HRE|rcsb pdb:2PNJ|rcsb pdb:2PO5|rcsb pdb:2PO7|rcsb pdb:2QD1|rcsb pdb:2QD2|rcsb pdb:2QD3|rcsb pdb:2QD4|rcsb pdb:2QD5|rcsb pdb:3AQI|rcsb pdb:3HCN|rcsb pdb:3HCO|rcsb pdb:3HCP|rcsb pdb:3HCR|rcsb pdb:3W1W|rcsb pdb:4F4D|rcsb pdb:4KLA|rcsb pdb:4KLC|rcsb pdb:4KLR|rcsb pdb:4KMM|rcsb pdb:4MK4|reactome:R-HSA-189451	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Rh4ulxUAnCedNUVAABAhY4iOnuo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UKB1-3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355213|ensembl:ENSP00000296933	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:q9ukb1-3(display_long)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	intact:EBI-355189(fbw1b_human)|ensembl:ENSG00000072803(gene)|ensembl:ENST00000296933(transcript)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:9D7VjRCZHE6TrLmSWDo1Ny+5WNw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:B4DH70	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-12503567	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:b4dh70_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0046983"(protein dimerization activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|refseq:XP_005265915.1|refseq:XP_016864769.1|interpro:IPR036047|interpro:IPR036322	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ugaxcsBEMZbZZiiBcCJC1iyGnUw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y4F1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96KP1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-465715|uniprotkb:Q5JPC8|uniprotkb:Q96AN6|uniprotkb:Q9NUZ8|uniprotkb:Q9UJM7|ensembl:ENSP00000230449|uniprotkb:B2RBE6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:exoc2_human(display_long)|uniprotkb:EXOC2(gene name)|psi-mi:EXOC2(display_short)|uniprotkb:SEC5(gene name synonym)|uniprotkb:SEC5L1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000112685(gene)|ensembl:ENST00000230449(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR029175|interpro:IPR039481|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016866507.1|refseq:XP_016866508.1|refseq:XP_016866509.1|refseq:XP_016866510.1|refseq:XP_016866511.1|refseq:XP_016866512.1|refseq:XP_016866513.1|refseq:NP_060773.3|dip:DIP-31795N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:7p+4vZ18z6u2PJY0GzbHY+ro0v89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75616	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6393536|ensembl:ENSP00000254928|uniprotkb:B3KN21|uniprotkb:C9JEC6|uniprotkb:O75617|uniprotkb:Q8WUY4|uniprotkb:Q96LE2|uniprotkb:Q96TC0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:eral1_human(display_long)|uniprotkb:ERAL1(gene name)|psi-mi:ERAL1(display_short)|uniprotkb:HERA(gene name synonym)|uniprotkb:Conserved ERA-like GTPase(gene name synonym)|uniprotkb:ERA-W(gene name synonym)|uniprotkb:ERA-like protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000132591(gene)|ensembl:ENST00000254928(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005662(GTP-binding protein Era)|interpro:IPR006073(GTP1/OBG)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR027417|interpro:IPR030388|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_005693.1|refseq:NP_001304914.1|refseq:NP_001304915.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2usCrRc4/GbXG5Ft8GY61w+rGds9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BZQ6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2556756|uniprotkb:B7ZLZ2|uniprotkb:Q9UFV7|uniprotkb:Q0VGM5|uniprotkb:B2RCH6|uniprotkb:Q9HCW1|uniprotkb:Q5TEZ0|uniprotkb:Q7L2Y5|ensembl:ENSP00000318147|intact:EBI-11137062	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:edem3_human(display_long)|uniprotkb:C1orf22(gene name synonym)|uniprotkb:EDEM3(gene name)|psi-mi:EDEM3(display_short)|uniprotkb:Alpha-1,2-mannosidase EDEM3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_079467.3|ensembl:ENSG00000116406(gene)|ensembl:ENST00000318130(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR003137(Protease-associated PA)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR037322|interpro:IPR044674|reactome:R-HSA-901032|refseq:NP_001306889.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Y+n8Hhal53ri5I8jlKzXI6S8pk09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8TBM8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2689808|uniprotkb:Q7Z3P0|uniprotkb:Q86TM0|uniprotkb:Q6UXN1|uniprotkb:Q86TA7|uniprotkb:Q9GZU9|ensembl:ENSP00000404381	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:djb14_human(display_long)|uniprotkb:UNQ9427/PRO34683(orf name)|uniprotkb:DNAJB14(gene name)|psi-mi:DNAJB14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:XP_011530564.1|refseq:NP_001026893.1|refseq:XP_011530565.1|refseq:NP_001265239.1|ensembl:ENSG00000164031(gene)|ensembl:ENST00000442697(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:jSZxKwwyWnOkxrtUOmuL0kAen289606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WW22	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2555157|uniprotkb:Q8N7P2|uniprotkb:Q6AW87|ensembl:ENSP00000339581|ensembl:ENSP00000378321|uniprotkb:E9PDM9|uniprotkb:Q8N5Z4	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnja4_human(display_long)|uniprotkb:DNAJA4(gene name)|psi-mi:DNAJA4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001123654.1|refseq:NP_001123655.1|refseq:NP_061072.3|ensembl:ENSG00000140403(gene)|ensembl:ENST00000343789(transcript)|ensembl:ENST00000394852(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q8WW22|reactome:R-HSA-3371497|refseq:XP_006720664.1|refseq:XP_005254592.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:GIrkxgRGaQvFml49F9iHH07gqTo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8TDD1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:VzxEkRaOIND08jGJk3yyoztesjo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13616	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P49674	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5RI15	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2834035|uniprotkb:Q8WV86|ensembl:ENSP00000406327	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cox20_human(display_long)|uniprotkb:COX20(gene name)|psi-mi:COX20(display_short)|uniprotkb:FAM36A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001299800.1|refseq:NP_932342.1|ensembl:ENSG00000203667(gene)|ensembl:ENST00000411948(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR022533|mint:Q5RI15|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:aEzOHrwpeXm+HutVUkXznyZci7k9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P12532	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q99653	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5JTW2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2562690|uniprotkb:Q9H9N3|uniprotkb:A1A4S8|uniprotkb:Q5JTW1|uniprotkb:Q5JTW0|uniprotkb:Q5BJE3|intact:EBI-10968071|uniprotkb:E9PHX5|ensembl:ENSP00000411284	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cep78_human(display_long)|uniprotkb:C9orf81(gene name synonym)|uniprotkb:CEP78(gene name)|psi-mi:CEP78(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001092272.1|refseq:NP_115547.1|refseq:NP_001317620.1|refseq:NP_001317622.1|refseq:NP_001317623.1|ensembl:ENSG00000148019(gene)|ensembl:ENST00000424347(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044782"(cilium organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR026212|interpro:IPR032675|mint:Q5JTW2|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:qtqlOeCnHrdYtYUFPxx8aMZ15is9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96SZ6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-372956|uniprotkb:Q5QP47|uniprotkb:Q9BVG6|uniprotkb:Q9BWZ5|uniprotkb:Q9H859|uniprotkb:Q9NZZ9|uniprotkb:Q9Y3F0|uniprotkb:A8K7R0|uniprotkb:Q5QP46|uniprotkb:Q5QP48|uniprotkb:Q675N4|uniprotkb:Q675N5|ensembl:ENSP00000350558	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ck5p1_human(display_long)|uniprotkb:CDK5RAP1(gene name)|psi-mi:CDK5RAP1(display_short)|uniprotkb:CDK5 activator-binding protein C42(gene name synonym)|uniprotkb:C20orf34(gene name synonym)|uniprotkb:CDK5 regulatory subunit-associated protein 1(gene name synonym)|uniprotkb:mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase(gene name synonym)|uniprotkb:"mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase"(gene name synonym)|uniprotkb:CGI-05(orf name)|uniprotkb:HSPC167(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_057492.2|refseq:NP_001265097.1|refseq:NP_001265098.1|refseq:NP_057166.4|ensembl:ENSG00000101391(gene)|ensembl:ENST00000357886(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035597"(N6-isopentenyladenosine methylthiotransferase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0070900"(mitochondrial tRNA modification)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006463("tRNA-i(6)A37 modification enzyme MiaB")|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:33pH+WYmB7Ub9Gi3y3JDiDV0rHo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O14735	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358858|uniprotkb:Q6FGU1|uniprotkb:Q6ZN70|ensembl:ENSP00000219789|ensembl:ENSP00000454453|ensembl:ENSP00000457339|uniprotkb:B4DUV0|uniprotkb:H3BTV1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cdipt_human(display_long)|uniprotkb:CDIPT(gene name)|psi-mi:CDIPT(display_short)|uniprotkb:PIS(gene name synonym)|uniprotkb:PIS1(gene name synonym)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001273514.1|refseq:NP_006310.1|ensembl:ENSG00000103502(gene)|ensembl:ENST00000219789(transcript)|ensembl:ENST00000569956(transcript)|ensembl:ENST00000570016(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043178"(alcohol binding)|go:"GO:0046341"(CDP-diacylglycerol metabolic process)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-HSA-1483226|dip:DIP-54492N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:SIs1nKd3UxZREA2Sxl4MxxBNYvM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96M89	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-8799407|ensembl:ENSP00000295124|uniprotkb:Q4ZG07|uniprotkb:Q86VL7|uniprotkb:Q53TE1|uniprotkb:Q6ZUY5|uniprotkb:Q05DF1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cc138_human(display_long)|uniprotkb:CCDC138(gene name)|psi-mi:CCDC138(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000163006(gene)|ensembl:ENST00000295124(transcript)|interpro:IPR038798|refseq:NP_001290034.1|refseq:NP_659415.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:76btOmprsisRfalbgA30aVF9xDk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P62158	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y297	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y297-2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-8826333|ensembl:ENSP00000385339	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:q9y297-2(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000166167(gene)|ensembl:ENST00000408038(transcript)|intact:EBI-307461(isoform-parent)|uniprotkb:Q9Y297-2(isoform-parent)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YJOz5b1YxD06O4tl4v4FyMpQP409606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UL15	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O95816	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96GD4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6P1M9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10252512|uniprotkb:Q9H969|uniprotkb:D3DX99|uniprotkb:Q68DB4|uniprotkb:Q9BVZ3|uniprotkb:B3KU88|ensembl:ENSP00000246174|ensembl:ENSP00000361827|ensembl:ENSP00000473737|ensembl:ENSP00000474470|ensembl:ENSP00000474484|ensembl:ENSP00000474720	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:armx5_human(display_long)|uniprotkb:ARMCX5(gene name)|psi-mi:ARMCX5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001161950.1|refseq:NP_001161951.1|refseq:NP_001161952.1|refseq:NP_001161954.1|refseq:NP_001161957.1|refseq:NP_073749.2|ensembl:ENSG00000125962(gene)|ensembl:ENST00000246174(transcript)|ensembl:ENST00000372742(transcript)|ensembl:ENST00000473968(transcript)|ensembl:ENST00000477663(transcript)|ensembl:ENST00000479502(transcript)|ensembl:ENST00000604957(transcript)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:3UWN1FlZWkUvvF1CIwdnejURUPc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q02952	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2562430|intact:EBI-2680946|uniprotkb:O00310|uniprotkb:O00498|uniprotkb:Q4LE68|uniprotkb:Q5SZ80|uniprotkb:Q5TGN1|uniprotkb:Q68D82|uniprotkb:Q99970|ensembl:ENSP00000253332|ensembl:ENSP00000384537	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:aka12_human(display_long)|uniprotkb:AKAP12(gene name)|psi-mi:AKAP12(display_short)|uniprotkb:AKAP250(gene name synonym)|uniprotkb:A-kinase anchor protein 250 kDa(gene name synonym)|uniprotkb:Gravin(gene name synonym)|uniprotkb:Myasthenia gravis autoantigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005091.2|refseq:NP_653080.1|ensembl:ENSG00000131016(gene)|ensembl:ENST00000253332(transcript)|ensembl:ENST00000402676(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061870"(positive regulation of hepatic stellate cell migration)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090036"(regulation of protein kinase C signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1900143"(positive regulation of oligodendrocyte apoptotic process)|interpro:IPR001573(Protein kinase A anchoring region)|interpro:IPR018459|interpro:IPR028540|mint:Q02952|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:XP_005267292.1|refseq:XP_016867006.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:vx4mziqb4PDChwfwSzb7mPrCn4w9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O95831	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O00116	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2838732|uniprotkb:A5D8U9|uniprotkb:Q2TU35|ensembl:ENSP00000264167	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:adas_human(display_long)|uniprotkb:AGPS(gene name)|psi-mi:AGPS(display_short)|uniprotkb:Aging-associated gene 5 protein(gene name synonym)|uniprotkb:Alkylglycerone-phosphate synthase(gene name synonym)|uniprotkb:AAG5(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003650.1|ensembl:ENSG00000018510(gene)|ensembl:ENST00000264167(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008609"(alkylglycerone-phosphate synthase activity)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR025650|interpro:IPR036318|mint:O00116|reactome:R-HSA-75896|reactome:R-HSA-9033241|reactome:R-HSA-9033500|interpro:IPR016166(FAD-binding, type 2)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:P8f6+j/f+WID0lFZnLIvVN5OSzM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P53396	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8TCN5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-9661677|uniprotkb:A8K911|uniprotkb:Q2TBF1|uniprotkb:Q6MZU0|uniprotkb:Q9UPR8|ensembl:ENSP00000312277|ensembl:ENSP00000348162	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:zn507_human(display_long)|uniprotkb:ZNF507(gene name)|psi-mi:ZNF507(display_short)|uniprotkb:KIAA1084(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001129628.1|refseq:NP_055725.2|dip:DIP-47281N|ensembl:ENSG00000168813(gene)|ensembl:ENST00000311921(transcript)|ensembl:ENST00000355898(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:KNkt4dQtObmBChpaGATZMuJNzeo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y2X9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-396200|uniprotkb:Q9NY92|uniprotkb:A6NF48|uniprotkb:B3KMX2|uniprotkb:Q5RKW5|intact:EBI-11018373|ensembl:ENSP00000294740|ensembl:ENSP00000356322	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:zn281_human(display_long)|uniprotkb:ZNF281(gene name)|psi-mi:ZNF281(display_short)|uniprotkb:GZP1(gene name synonym)|uniprotkb:ZBP99(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 99(gene name synonym)|uniprotkb:Transcription factor ZBP-99(gene name synonym)|uniprotkb:GC-box-binding zinc finger protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_036614.1|refseq:NP_001268222.1|refseq:NP_001268223.1|refseq:XP_016856376.1|refseq:XP_016856377.1|ensembl:ENSG00000162702(gene)|ensembl:ENST00000294740(transcript)|ensembl:ENST00000367353(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y2X9	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:bjmz9ne6FkC0kbJUv13u8IoDYHM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P63104	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P27348	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P62258	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P31946	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96TA2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O43592	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NNW5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UN37	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1171942|uniprotkb:Q8TF07|uniprotkb:Q9UI03|uniprotkb:Q9Y582|uniprotkb:B2RCB7|ensembl:ENSP00000254950	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:vps4a_human(display_long)|uniprotkb:VPS4-1(gene name synonym)|uniprotkb:Protein SKD2(gene name synonym)|uniprotkb:VPS4A(gene name)|psi-mi:VPS4A(display_short)|uniprotkb:VPS4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_037377.1|ensembl:ENSG00000132612(gene)|ensembl:ENST00000254950(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1904896"(ESCRT complex disassembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|mint:Q9UN37|rcsb pdb:1YXR|rcsb pdb:2JQ9|rcsb pdb:2K3W|reactome:R-HSA-162588|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9668328|interpro:IPR031255|dip:DIP-44585N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:kr3zmre/ELTm2b/fCytp8IlBUhs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P22695	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y5K5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P11441	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356983|uniprotkb:Q5HY80|ensembl:ENSP00000358674	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ubl4a_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)|uniprotkb:GDX(gene name synonym)|uniprotkb:DXS254E(gene name synonym)|uniprotkb:UBL4(gene name synonym)|uniprotkb:Ubiquitin-like protein GDX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055050.1|ensembl:ENSG00000102178(gene)|ensembl:ENST00000369660(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016020"(membrane)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|mint:P11441|rcsb pdb:2DZI|rcsb pdb:4WWR|rcsb pdb:4X86|reactome:R-HSA-9609523	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:euKOrDRC1mx0s2QVY95010PRaIg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BSJ2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BUF5	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P68371	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13509	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13885	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P07437	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P68363	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O94826	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5SNT2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10986145|ensembl:ENSP00000344503|uniprotkb:Q5SNT3|uniprotkb:B9EH90	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tm201_human(display_long)|uniprotkb:TMEM201(gene name)|psi-mi:TMEM201(display_short)|uniprotkb:NET5(gene name synonym)|uniprotkb:SAMP1(gene name synonym)|uniprotkb:Spindle-associated membrane protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001010866.1|refseq:NP_001124396.2|refseq:XP_011539212.1|ensembl:ENSG00000188807(gene)|ensembl:ENST00000340381(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR018617|interpro:IPR018861|interpro:IPR040041	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YAYQ9viEL2HvpBxeStvJQrQ/z2c9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NZ01	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BQ70	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-745182|uniprotkb:Q2MK75|uniprotkb:Q9UPV3|ensembl:ENSP00000263346|ensembl:ENSP00000491638	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tcf25_human(display_long)|uniprotkb:Nuclear localized protein 1(gene name synonym)|uniprotkb:TCF25(gene name)|psi-mi:TCF25(display_short)|uniprotkb:KIAA1049(gene name synonym)|uniprotkb:NULP1(gene name synonym)|uniprotkb:FKSG26(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055787.1|ensembl:ENSG00000141002(gene)|ensembl:ENST00000263346(transcript)|ensembl:ENST00000640279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:1990112"(RQC complex)|interpro:IPR006994(Basic helix-loop-helix, Nulp1-type)|interpro:IPR011990(Tetratricopeptide-like helical)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:+UEKIIV2LaFWrqJiOWgGU74ITVM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13188	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:slrC4Ax6263chBC1DJygdoExuCc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P31948	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P51571	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13501	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q92540	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UQE7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q14683	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6P1M0	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BQT8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6268670|ensembl:ENSP00000329452|uniprotkb:A8K0L0|uniprotkb:G3V4L5|uniprotkb:Q3MJ99	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:odc_human(display_long)|uniprotkb:SLC25A21(gene name)|psi-mi:SLC25A21(display_short)|uniprotkb:ODC(gene name synonym)|uniprotkb:Solute carrier family 25 member 21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000183032(gene)|ensembl:ENST00000331299(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006554"(lysine catabolic process)|go:"GO:0015139"(alpha-ketoglutarate transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1990550"(mitochondrial alpha-ketoglutarate transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-71064|refseq:NP_001164641.1|refseq:NP_085134.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:vjU+HXQnFdVrJ80S6EAyBasaypc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P53985	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6P4A7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1049439|uniprotkb:Q6WSU4|uniprotkb:Q86TD9|ensembl:ENSP00000347924	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sfxn4_human(display_long)|uniprotkb:Breast cancer resistance marker 1(gene name synonym)|uniprotkb:SFXN4(gene name)|psi-mi:SFXN4(display_short)|uniprotkb:BCRM1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_998814.1|refseq:XP_011537584.1|refseq:XP_005269583.1|refseq:XP_005269584.1|ensembl:ENSG00000183605(gene)|ensembl:ENST00000355697(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006865"(amino acid transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|interpro:IPR028825	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:D/Ae1Kd5aIiliqNVmS7aFaIpwsk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96NB2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6381136|ensembl:ENSP00000358909|uniprotkb:Q5JSM6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sfxn2_human(display_long)|uniprotkb:SFXN2(gene name)|psi-mi:SFXN2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:XP_016871152.1|refseq:XP_011537564.1|ensembl:ENSG00000156398(gene)|ensembl:ENST00000369893(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|refseq:NP_849189.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:FNAgN69aAzlfW03f5i/uS+0NSaE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9P0U3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2822935|uniprotkb:A8K7P5|uniprotkb:Q86XC8|ensembl:ENSP00000394791|ensembl:ENSP00000447328	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:senp1_human(display_long)|uniprotkb:SENP1(gene name)|psi-mi:SENP1(display_short)|uniprotkb:Sentrin/SUMO-specific protease SENP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001254523.1|refseq:NP_001254524.1|ensembl:ENSG00000079387(gene)|ensembl:ENST00000448372(transcript)|ensembl:ENST00000549518(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|mint:Q9P0U3|rcsb pdb:2CKG|rcsb pdb:2CKH|rcsb pdb:2G4D|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2IYC|rcsb pdb:2IYD|rcsb pdb:2XPH|rcsb pdb:2XRE|rcsb pdb:6NNQ|reactome:R-HSA-3065679|reactome:R-HSA-9035034|go:"GO:0016926"(protein desumoylation)|dip:DIP-29252N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:8Mzw65/M5iQc30wCqYASiiWet5U9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O15027	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WVM8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y3Z3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9H6T3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356928|uniprotkb:Q6PHR5|uniprotkb:B4DRW9|ensembl:ENSP00000005386	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rpap3_human(display_long)|uniprotkb:RPAP3(gene name)|psi-mi:RPAP3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001139547.1|refseq:NP_001139548.1|refseq:NP_078880.2|dip:DIP-47508N|ensembl:ENSG00000005175(gene)|ensembl:ENST00000005386(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0097255"(R2TP complex)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR025986|mint:Q9H6T3|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:6EZ4|rcsb pdb:6FD7|rcsb pdb:6FDP|rcsb pdb:6FDT|rcsb pdb:6FM8|rcsb pdb:6FO1|rcsb pdb:6GXZ|rcsb pdb:6ZBK	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:pN6/ClY+oonHFRAFtpcGeZ/OTEQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WVD3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-749039|uniprotkb:Q9H8K2|uniprotkb:Q9UF87|uniprotkb:Q9UKI6|uniprotkb:B2RE17|ensembl:ENSP00000261593	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rn138_human(display_long)|uniprotkb:RING finger protein 138(gene name synonym)|uniprotkb:Nemo-like kinase-associated RING finger protein(gene name synonym)|uniprotkb:RNF138(gene name)|psi-mi:RNF138(display_short)|uniprotkb:NARF(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF138(gene name synonym)|uniprotkb:HSD-4(orf name)|uniprotkb:HSD4(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_057355.2|refseq:NP_937761.1|refseq:NP_001178253.2|refseq:XP_005258343.1|ensembl:ENSG00000134758(gene)|ensembl:ENST00000261593(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034734|reactome:R-HSA-983168	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:HhGscRenFoqXTiZxHR62E4wcIo09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6R327	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1387196|uniprotkb:Q68DT5|uniprotkb:Q86UB7|uniprotkb:Q8N3A0|uniprotkb:Q8NCM6|uniprotkb:B2RNX0|uniprotkb:B7ZMF7|ensembl:ENSP00000349959	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rictr_human(display_long)|uniprotkb:RICTOR(gene name)|psi-mi:RICTOR(display_short)|uniprotkb:KIAA1999(gene name synonym)|uniprotkb:AVO3 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001272368.1|refseq:NP_001272369.1|refseq:NP_689969.2|dip:DIP-39479N|ensembl:ENST00000357387(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0043022"(ribosome binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028267|interpro:IPR028268|interpro:IPR029259|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|mint:Q6R327|rcsb pdb:5ZCS|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|reactome:R-HSA-6804757|ensembl:ENSG00000164327(gene)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:LlVf8U/ZLBh0fYyzx8RzSpm+1sc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P40937	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P04049	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5XKP0	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1053887|uniprotkb:Q86YE5|uniprotkb:A0A0B4J2A5|uniprotkb:K7EKR0|ensembl:ENSP00000309561	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:mic13_human(display_long)|uniprotkb:MICOS13(gene name)|psi-mi:MICOS13(display_short)|uniprotkb:C19orf70(gene name synonym)|uniprotkb:MIC13(gene name synonym)|uniprotkb:Protein P117(gene name synonym)|uniprotkb:QIL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_991330.1|ensembl:ENSG00000174917(gene)|ensembl:ENST00000309324(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0044284"(mitochondrial crista junction)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR026769|reactome:R-HSA-8949613|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|refseq:NP_001295169.1|refseq:XP_016881737.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:WXuGrcp9zyQSBo/4yW2yQ1uSf/A9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q86YD1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-722211|uniprotkb:Q6UXX7|uniprotkb:Q96BU3|uniprotkb:Q9HBN4|uniprotkb:Q9NYL1|ensembl:ENSP00000375717|ensembl:ENSP00000469128|ensembl:ENSP00000472816	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ptov1_human(display_long)|uniprotkb:Activator interaction domain-containing protein 2(gene name synonym)|uniprotkb:PP642(orf name)|uniprotkb:UNQ6127/PRO20092(orf name)|uniprotkb:PTOV1(gene name)|psi-mi:PTOV1(display_short)|uniprotkb:ACID2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_059128.2|refseq:NP_001292034.1|refseq:NP_001292037.1|ensembl:ENSG00000104960(gene)|ensembl:ENST00000391842(transcript)|ensembl:ENST00000599732(transcript)|ensembl:ENST00000601675(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR021394|interpro:IPR038196|mint:Q86YD1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IHNzBJdo2bMbeep+32jeZct4czM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P49721	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5THK1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1773550|uniprotkb:Q5THK4|uniprotkb:Q6ZNN1|uniprotkb:Q6ZWH0|uniprotkb:Q8IW74|uniprotkb:Q9H5T4|ensembl:ENSP00000331845	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pr14l_human(display_long)|uniprotkb:PRR14L(gene name)|psi-mi:PRR14L(display_short)|uniprotkb:C22orf30(gene name synonym)|uniprotkb:Proline rich 14-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:XP_011528382.1|refseq:XP_011528383.1|refseq:NP_775837.2|refseq:XP_006724282.1|refseq:XP_006724283.1|ensembl:ENSP00000331845|refseq:XP_016884225.1|refseq:XP_016884226.1|ensembl:ENSG00000183530(gene)|ensembl:ENST00000327423(transcript)|interpro:IPR026320|interpro:IPR028149	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:JPwD2Kz4L2brrLfT41iriYT2Pos9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P78527	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P30048	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P53041	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-716663|uniprotkb:Q53XV2|uniprotkb:Q16722|ensembl:ENSP00000012443	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ppp5_human(display_long)|uniprotkb:Protein phosphatase T(gene name synonym)|uniprotkb:PPP5C(gene name)|psi-mi:PPP5C(display_short)|uniprotkb:PPP5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006238.1|ensembl:ENSG00000011485(gene)|ensembl:ENST00000012443(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0101031"(chaperone complex)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1904550"(response to arachidonic acid)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011236(Protein phosphatase 5)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013235(Serine/threonine phosphatase, PPP5)|interpro:IPR019734|interpro:IPR029052|interpro:IPR041753|mint:P53041|rcsb pdb:1A17|rcsb pdb:1S95|rcsb pdb:1WAO|rcsb pdb:2BUG|rcsb pdb:3H60|rcsb pdb:3H61|rcsb pdb:3H62|rcsb pdb:3H63|rcsb pdb:3H64|rcsb pdb:3H66|rcsb pdb:3H67|rcsb pdb:3H68|rcsb pdb:3H69|rcsb pdb:4ZVZ|rcsb pdb:4ZX2|rcsb pdb:5HPE|rcsb pdb:5UI1|rcsb pdb:5WG8|reactome:R-HSA-5675221|reactome:R-HSA-5693565|reactome:R-HSA-8939211|dip:DIP-29043N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:5QoNB467ftOvWaUNfSm6RalR8+Y9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P30153	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q07864	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-348526|uniprotkb:Q13533|intact:EBI-28987244|ensembl:ENSP00000322570|uniprotkb:Q86VH9	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dpoe1_human(display_long)|uniprotkb:POLE(gene name)|psi-mi:POLE(display_short)|uniprotkb:POLE1(gene name synonym)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006222.2|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|go:"GO:0008270"(zinc ion binding)|ensembl:ENSG00000177084(gene)|ensembl:ENST00000320574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|ensembl:ENSP00000322570|dip:DIP-24243N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:oPDFCAO2AeDB4UjbeBvo8DPi+ow9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O43164	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1996038|uniprotkb:D3DSZ5|uniprotkb:Q68D49|uniprotkb:Q8N1G5|uniprotkb:A8K6U4|ensembl:ENSP00000354775|ensembl:ENSP00000355284	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pja2_human(display_long)|uniprotkb:PJA2(gene name)|psi-mi:PJA2(display_short)|uniprotkb:KIAA0438(gene name synonym)|uniprotkb:RNF131(gene name synonym)|uniprotkb:RING finger protein 131(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Praja-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055634.3|refseq:XP_016865588.1|ensembl:ENSG00000198961(gene)|ensembl:ENST00000361189(transcript)|ensembl:ENST00000361557(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007616"(long-term memory)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030639|mint:O43164|reactome:R-HSA-983168|dip:DIP-47040N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:z0OkXLozXymqwyF+xQR+PFa+bQI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UG56	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-721929|uniprotkb:O43207|uniprotkb:O95535|uniprotkb:Q6IC28|uniprotkb:Q96GQ2|uniprotkb:Q9UGA9|ensembl:ENSP00000391739|uniprotkb:B1AKM7	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pisd_human(display_long)|uniprotkb:PISD(gene name)|psi-mi:PISD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000241878(gene)|ensembl:ENST00000439502(transcript)|go:"GO:0004609"(phosphatidylserine decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|interpro:IPR003817(Phosphatidylserine decarboxylase-related)|interpro:IPR033177|interpro:IPR033661|reactome:R-HSA-1483213|refseq:NP_055153.1|refseq:NP_001313340.1|refseq:NP_001313344.1|refseq:NP_001313345.1|refseq:NP_001313346.1|refseq:NP_821141.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:3X2aiRWVuM4Iow/j9SlUlMvuP2s9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q99570	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q92569	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-79893|intact:EBI-28975437|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|uniprotkb:O60482|uniprotkb:Q5T4P2|uniprotkb:B2R9C1|uniprotkb:Q5T4P1|uniprotkb:D3DQ12	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:p55g_human(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma(gene name synonym)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short)|uniprotkb:p55PIK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|ensembl:ENSG00000117461(gene)|ensembl:ENST00000262741(transcript)|ensembl:ENST00000372006(transcript)|ensembl:ENST00000420542(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|mint:Q92569|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-2219530|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-512988|reactome:R-HSA-6811558|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|reactome:R-HSA-8853659|reactome:R-HSA-9009391|refseq:NP_001107644.1|refseq:NP_003620.3|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|ensembl:ENST00000423209|ensembl:ENSP00000391431|dip:DIP-30925N|refseq:NP_001290358.1|refseq:XP_016858103.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:oIVTuGRhg/Kn3h+Br1EfiAtiAQQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O15067	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1052653|uniprotkb:A6H8V8|ensembl:ENSP00000313490	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pur4_human(display_long)|uniprotkb:Formylglycinamide ribotide amidotransferase(gene name synonym)|uniprotkb:PFAS(gene name)|psi-mi:PFAS(display_short)|uniprotkb:KIAA0361(gene name synonym)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_036525.1|ensembl:ENSG00000178921(gene)|ensembl:ENST00000314666(transcript)|go:"GO:0004642"(phosphoribosylformylglycinamidine synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097065"(anterior head development)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR029062|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR040707|interpro:IPR041609|mint:O15067|reactome:R-HSA-73817	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:e52AyHjHUrLjnoJP+rInkcvfGJk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BRX2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:CGI-17(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000152684(gene)|ensembl:ENST00000274311(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|refseq:NP_057030.3	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BZF1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:osbl8_human(display_long)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001003712.1|refseq:NP_065892.1|refseq:NP_001306581.1|refseq:NP_001306584.1|ensembl:ENSG00000091039(gene)|ensembl:ENST00000261183(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0140343"(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|reactome:R-HSA-1482801|refseq:XP_005268678.1|refseq:XP_006719287.1|dip:DIP-56130N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BSD7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2689235|ensembl:ENSP00000355587	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_115700.1|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|ensembl:ENSG00000135778(gene)|ensembl:ENST00000366628(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|refseq:NP_001316382.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9ULX3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-373285|uniprotkb:Q7L6B7|uniprotkb:Q7M4M4|uniprotkb:Q7Z4B5|uniprotkb:Q9NWB0|ensembl:ENSP00000268802	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:nob1_human(display_long)|uniprotkb:NOB1(gene name)|psi-mi:NOB1(display_short)|uniprotkb:Protein ART-4(gene name synonym)|uniprotkb:Phosphorylation regulatory protein HP-10(gene name synonym)|uniprotkb:ART4(gene name synonym)|uniprotkb:NOB1P(gene name synonym)|uniprotkb:PSMD8BP1(gene name synonym)|uniprotkb:MSTP158(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_054781.1|ensembl:ENSG00000141101(gene)|ensembl:ENST00000268802(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0046872"(metal ion binding)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR014881("Nin one binding (NOB1) Zn-ribbon like")|interpro:IPR017117(D-site 20S pre-rRNA nuclease)|interpro:IPR033411|interpro:IPR033461|interpro:IPR036283|interpro:IPR039907|mint:Q9ULX3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|reactome:R-HSA-6791226	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:/Xk2PcxpyxjcG5gvs2VtLK6QmvA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6ZNB6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6117166|uniprotkb:B1Q2K1|uniprotkb:Q86VG1|uniprotkb:Q8WVH1|ensembl:ENSP00000333113|ensembl:ENSP00000370949|ensembl:ENSP00000422037	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:nfxl1_human(display_long)|uniprotkb:NFXL1(gene name)|psi-mi:NFXL1(display_short)|uniprotkb:OZFP(gene name synonym)|uniprotkb:Ovarian zinc finger protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_694540.3|refseq:NP_001265552.1|refseq:NP_001265553.1|ensembl:ENSG00000170448(gene)|ensembl:ENST00000329043(transcript)|ensembl:ENST00000381538(transcript)|ensembl:ENST00000507489(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR034078	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IYD8+e0p5antDKQ2E+5N7UduDLQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O95168	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O96000	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q16795	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P51970	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1237250|uniprotkb:B1AM93|uniprotkb:Q9Y6N0|ensembl:ENSP00000362873	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ndua8_human(display_long)|uniprotkb:NDUFA8(gene name)|psi-mi:NDUFA8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055037.1|ensembl:ENSG00000119421(gene)|ensembl:ENST00000373768(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:P51970|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:buGk0RR4rNyaFDdsjenBqzYzlMs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O95299	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1246361|uniprotkb:Q8WXC9|ensembl:ENSP00000252711|ensembl:ENSP00000503956|ensembl:ENSP00000504765	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:nduaa_human(display_long)|uniprotkb:NDUFA10(gene name)|psi-mi:NDUFA10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_004535.1|ensembl:ENSG00000130414(gene)|ensembl:ENST00000252711(transcript)|ensembl:ENST00000676929(transcript)|ensembl:ENST00000678158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:O95299|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:8jwJPJ0rD9H7A4AzxPd186tpXYs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P42695	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P55209	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6UB35	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1046835|intact:EBI-28986171|ensembl:ENSP00000356290|uniprotkb:Q2TBF3|uniprotkb:Q8WVW0|uniprotkb:Q96HG8|uniprotkb:Q9H789|uniprotkb:Q9UFU8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:c1tm_human(display_long)|uniprotkb:MTHFD1L(gene name)|psi-mi:MTHFD1L(display_short)|uniprotkb:FTHFSDC1(gene name synonym)|uniprotkb:Formyltetrahydrofolate synthetase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000120254(gene)|ensembl:ENST00000367321(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006760"(folic acid-containing compound metabolic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0015942"(formate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR027417|interpro:IPR036291|reactome:R-HSA-196757|refseq:NP_001229696.1|refseq:NP_001229697.1|refseq:NP_001229698.1|refseq:NP_056255.2|ensembl:ENST00000367307|ensembl:ENSP00000356276|ensembl:ENSP00000356290	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:lJRND1kcMEF99+fT1b+X8hfuLHM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P11586	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3|ensembl:ENSP00000498336|ensembl:ENSP00000498511	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005947.3|dip:DIP-33682N|ensembl:ENSG00000100714(gene)|ensembl:ENST00000651537(transcript)|ensembl:ENST00000652337(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004477"(methenyltetrahydrofolate cyclohydrolase activity)|go:"GO:0004486"("methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity")|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0009069"(serine family amino acid metabolic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0061053"(somite development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BPZ7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-749938|uniprotkb:Q00426|intact:EBI-1237531|uniprotkb:A8K1Z5|uniprotkb:B1AMA4|uniprotkb:Q5JSV5|uniprotkb:Q5JSV6|uniprotkb:Q5JSV9|uniprotkb:Q658R0|uniprotkb:Q699U1|uniprotkb:Q699U2|uniprotkb:Q699U3|uniprotkb:Q699U4|uniprotkb:Q6GVJ0|uniprotkb:Q6GVJ1|uniprotkb:Q6GVJ2|intact:EBI-1048293|uniprotkb:B7Z309|ensembl:ENSP00000265960|ensembl:ENSP00000362597	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sin1_human(display_long)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2-associated protein 1(gene name synonym)|uniprotkb:Stress-activated map kinase-interacting protein 1(gene name synonym)|uniprotkb:MAPKAP1(gene name)|psi-mi:MAPKAP1(display_short)|uniprotkb:SIN1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001006618.1|refseq:NP_001006619.1|refseq:NP_001006620.1|refseq:NP_001006621.1|refseq:NP_001006622.1|refseq:NP_077022.1|refseq:XP_011517312.1|refseq:XP_016870615.1|dip:DIP-39480N|ensembl:ENSG00000119487(gene)|ensembl:ENST00000265960(transcript)|ensembl:ENST00000373498(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031932"(TORC2 complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|interpro:IPR008828(Stress-activated map kinase interacting 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031313|interpro:IPR031567|interpro:IPR032679|mint:Q9BPZ7|rcsb pdb:3VOQ|rcsb pdb:5ZCS|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|reactome:R-HSA-6804757|refseq:XP_016870616.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:kIAa8HfqaJhvssnCDV2/8fj3JYA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8IWC1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1050284|uniprotkb:A6NCZ7|uniprotkb:A2A2J0|uniprotkb:A6NHR4|uniprotkb:Q5JXI5|uniprotkb:Q5JXI6|uniprotkb:Q9H9M8|uniprotkb:Q6P2S1|uniprotkb:B4DWD2|uniprotkb:H7BY77|ensembl:ENSP00000318086	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ma7d3_human(display_long)|uniprotkb:MAP7D3(gene name)|psi-mi:MAP7D3(display_short)|uniprotkb:MDP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001166987.1|refseq:NP_001166988.1|refseq:NP_078873.2|ensembl:ENSG00000129680(gene)|ensembl:ENST00000316077(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0046785"(microtubule polymerization)|interpro:IPR008604(E-MAP-115)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:9WwXvs5DT9zh5c7DC27VuemEeU09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y5V3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96AG4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q15345	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-721408|uniprotkb:A8K5G8|uniprotkb:Q3MJ96|uniprotkb:Q5TDF5|uniprotkb:Q71RA8|uniprotkb:Q9BSM0|ensembl:ENSP00000343298|ensembl:ENSP00000477792	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:lrc41_human(display_long)|uniprotkb:Protein Muf1(gene name synonym)|uniprotkb:LRRC41(gene name)|psi-mi:LRRC41(display_short)|uniprotkb:PP7759(orf name)|uniprotkb:MUF1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006360.3|ensembl:ENSG00000132128(gene)|ensembl:ENST00000343304(transcript)|ensembl:ENST00000617190(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|interpro:IPR026137|interpro:IPR032675|reactome:R-HSA-8951664|reactome:R-HSA-9706019|reactome:R-HSA-983168	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:56q0Bi44fuNOnpKChVlLLpY4/I09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8NF37	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-922595|uniprotkb:Q1HAQ1|uniprotkb:Q7Z4G6|uniprotkb:Q8N3U7|uniprotkb:Q8WUL8|uniprotkb:Q9GZW6|ensembl:ENSP00000283415|ensembl:ENSP00000423472	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pcat1_human(display_long)|uniprotkb:1-alkylglycerophosphocholine O-acetyltransferase(gene name synonym)|uniprotkb:Acyltransferase-like 2(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 3(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase(gene name synonym)|uniprotkb:1-alkenylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:LPCAT1(gene name)|psi-mi:LPCAT1(display_short)|uniprotkb:AYTL2(gene name synonym)|uniprotkb:PFAAP3(gene name synonym)|uniprotkb:"Acetyl-CoA:lyso-platelet-activating factor acetyltransferase"(gene name synonym)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_079106.3|ensembl:ENSG00000153395(gene)|ensembl:ENST00000283415(transcript)|ensembl:ENST00000475622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0047159"(1-alkenylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047191"(1-alkylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047192"(1-alkylglycerophosphocholine O-acetyltransferase activity)|go:"GO:0050200"(plasmalogen synthase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR011992(EF-Hand type)|reactome:R-HSA-1482788|reactome:R-HSA-1482925|reactome:R-HSA-1483166|reactome:R-HSA-1483191|reactome:R-HSA-6798695	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:sJPdIAauFmV71N/KwIUH75hTHv09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y2U8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2561428|ensembl:ENSP00000308369|uniprotkb:Q9NT47|uniprotkb:Q9NYA5	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000174106(gene)|ensembl:ENST00000308330(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR034997|interpro:IPR035979|interpro:IPR041885|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75153	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-308505|uniprotkb:Q6AHY2|uniprotkb:Q6P3X7|uniprotkb:Q6ZUG8|uniprotkb:Q8N4U7|uniprotkb:Q9BTA3|uniprotkb:Q9H979|ensembl:ENSP00000388872|ensembl:ENSP00000458986	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:clu_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)|uniprotkb:KIAA0664(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_056044.3|ensembl:ENSG00000132361(gene)|ensembl:ENST00000435359(transcript)|ensembl:ENST00000570628(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231|interpro:IPR025697|interpro:IPR027523|interpro:IPR028275|interpro:IPR033646	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:9605WkS82JBvT0JZ1fkpxe3SqRc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:A3KMH1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O14654	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P51617	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6DN90	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-3044091|uniprotkb:Q96D85|uniprotkb:O94863|uniprotkb:A0A087WWK8|ensembl:ENSP00000273221	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:iqec1_human(display_long)|uniprotkb:IQSEC1(gene name)|psi-mi:IQSEC1(display_short)|uniprotkb:ARFGEP100(gene name synonym)|uniprotkb:BRAG2(gene name synonym)|uniprotkb:KIAA0763(gene name synonym)|uniprotkb:ADP-ribosylation factors guanine nucleotide-exchange protein 100(gene name synonym)|uniprotkb:ADP-ribosylation factors guanine nucleotide-exchange protein 2(gene name synonym)|uniprotkb:Brefeldin-resistant Arf-GEF 2 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055684.3|refseq:NP_001317548.1|refseq:NP_001127854.1|refseq:XP_011532617.1|ensembl:ENSG00000144711(gene)|ensembl:ENST00000273221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0060996"(dendritic spine development)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR030737|interpro:IPR033742|interpro:IPR035999|rcsb pdb:3QWM|rcsb pdb:4C0A|rcsb pdb:5NLV|rcsb pdb:5NLY|rcsb pdb:6FNE	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IOpjszM2OA5kfLxShJv1S6+sANI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q86VI3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1237354|uniprotkb:Q5T3H8|ensembl:ENSP00000354451	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:iqga3_human(display_long)|uniprotkb:IQGAP3(gene name)|psi-mi:IQGAP3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_839943.2|ensembl:ENSP00000354451|ensembl:ENSG00000183856(gene)|ensembl:ENST00000361170(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051015"(actin filament binding)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070856"(myosin VI light chain binding)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|mint:Q86VI3|rcsb pdb:3ISU|reactome:R-HSA-5626467|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|interpro:IPR036872	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:5lIYEC2lJihenWFio0Q+1W9EINI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8TEX9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P10809	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P11142	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P17066	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P34932	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P55084	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P40939	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y5Q9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1054873|uniprotkb:Q4ZG48|uniprotkb:Q86XJ8|uniprotkb:Q8WX84|uniprotkb:Q96B44|uniprotkb:Q9H5I8|uniprotkb:Q9NT97|intact:EBI-1237212|ensembl:ENSP00000263956	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tf3c3_human(display_long)|uniprotkb:GTF3C3(gene name)|psi-mi:GTF3C3(display_short)|uniprotkb:Transcription factor IIIC subunit gamma(gene name synonym)|uniprotkb:Transcription factor IIIC 102 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001193703.1|refseq:NP_036218.1|ensembl:ENSG00000119041(gene)|ensembl:ENST00000263956(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039340|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:cF53nd62xSXQfZerd7bdfB2KUgk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P78347	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96D09	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P06280	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2513305|ensembl:ENSP00000218516|uniprotkb:Q6LER7	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:agal_human(display_long)|uniprotkb:GLA(gene name)|psi-mi:GLA(display_short)|uniprotkb:Alpha-D-galactoside galactohydrolase(gene name synonym)|uniprotkb:Alpha-D-galactosidase A(gene name synonym)|uniprotkb:Melibiase(gene name synonym)|uniprotkb:Galactosylgalactosylglucosylceramidase GLA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	reactome:R-HSA-1660662|reactome:R-HSA-6798695|ensembl:ENSG00000102393(gene)|ensembl:ENST00000218516(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004557"(alpha-galactosidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016936"(galactoside binding)|go:"GO:0017041"(galactosylgalactosylglucosylceramidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046477"(glycosylceramide catabolic process)|go:"GO:0046479"(glycosphingolipid catabolic process)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0052692"(raffinose alpha-galactosidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000111(Glycoside hydrolase, clan GH-D)|interpro:IPR002241(Glycoside hydrolase, family 27)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR035373|rcsb pdb:1R46|rcsb pdb:1R47|rcsb pdb:3GXN|rcsb pdb:3GXP|rcsb pdb:3GXT|rcsb pdb:3HG2|rcsb pdb:3HG3|rcsb pdb:3HG4|rcsb pdb:3HG5|rcsb pdb:3LX9|rcsb pdb:3LXA|rcsb pdb:3LXB|rcsb pdb:3LXC|rcsb pdb:3S5Y|rcsb pdb:3S5Z|rcsb pdb:3TV8|rcsb pdb:4NXS|rcsb pdb:6IBK|rcsb pdb:6IBM|rcsb pdb:6IBR|rcsb pdb:6IBT|refseq:NP_000160.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:en4+xuRp2k6kcAkvM2Bla9N3+189606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q92616	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q92538	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359050|uniprotkb:Q5VXX3|uniprotkb:Q96CK6|uniprotkb:Q96HZ3|uniprotkb:Q9H473|uniprotkb:Q149P0|uniprotkb:Q149P1|ensembl:ENSP00000503207|ensembl:ENSP00000503981	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gbf1_human(display_long)|uniprotkb:GBF1(gene name)|psi-mi:GBF1(display_short)|uniprotkb:KIAA0248(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001186307.1|refseq:NP_001186308.1|refseq:NP_004184.1|ensembl:ENSP00000503207|ensembl:ENSP00000503981|ensembl:ENST00000676993|ensembl:ENSP00000503918|ensembl:ENST00000677240|ensembl:ENSP00000503428|ensembl:ENSG00000107862(gene)|ensembl:ENST00000676513(transcript)|ensembl:ENST00000676939(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0060271"(cilium assembly)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|mint:Q92538|reactome:R-HSA-199992|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4rA/2NVw35m+b6O7/+9noI3EO4o9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P22102	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13045	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-351549|ensembl:ENSP00000491480|ensembl:ENSP00000324573|uniprotkb:B4DIL0|uniprotkb:F5H407|uniprotkb:J3QLG3	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:flii_human(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002009.1|refseq:NP_001243193.1|ensembl:ENST00000327031(transcript)|ensembl:ENST00000638207(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030239"(myofibril assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029919|interpro:IPR032675|mint:Q13045|ensembl:ENSG00000177731(gene)|ensembl:ENSG00000284571(gene)|refseq:NP_001243194.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:hzls0Ir+lr0+wNsTUeIURV3fXVQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q14318	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y285	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O94887	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2806886|uniprotkb:Q53QM5|uniprotkb:Q9UFE7|uniprotkb:Q8WU27|ensembl:ENSP00000264042|uniprotkb:B7Z6J8|uniprotkb:F5GZ84	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:farp2_human(display_long)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:PLEKHC3(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 3(gene name synonym)|uniprotkb:FERM domain-including RhoGEF(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001269912.1|refseq:NP_001269913.1|refseq:NP_055623.1|ensembl:ENSG00000006607(gene)|ensembl:ENST00000264042(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0022405"(hair cycle process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0033623"(regulation of integrin activation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071800"(podosome assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|reactome:R-HSA-399955|reactome:R-HSA-9013149	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WVX9	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y3D0	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-744045|ensembl:ENSP00000387471	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96RT1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|ensembl:ENSP00000284037|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001240628.1|refseq:NP_001240630.1|ensembl:ENSG00000112851(gene)|ensembl:ENST00000284037(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045175"(basal protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBG|rcsb pdb:6UBH|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013408|reactome:R-HSA-9013106|reactome:R-HSA-9013423|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_061165.1|refseq:NP_001240626.1|refseq:NP_001240627.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P50402	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9H8V3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1054039|uniprotkb:Q9NSV8|uniprotkb:Q9NVW9|uniprotkb:Q0MT80|uniprotkb:Q6U836|uniprotkb:Q2M269|ensembl:ENSP00000376457	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ect2_human(display_long)|uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)|uniprotkb:ECT2(gene name)|psi-mi:ECT2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:XP_011510816.1|refseq:NP_060568.3|refseq:NP_001245244.1|refseq:NP_001245245.1|ensembl:ENSG00000114346(gene)|ensembl:ENST00000392692(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097149"(centralspindlin complex)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036420|mint:Q9H8V3|rcsb pdb:3L46|rcsb pdb:4N40|rcsb pdb:6L30|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR026817|interpro:IPR035899|dip:DIP-47496N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ApqtJWU8n3b+PM8yUysFwFOkWuk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75521	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2512024|ensembl:ENSP00000369461|uniprotkb:Q9NYH7|uniprotkb:Q9NQH1|uniprotkb:Q9H0T9|uniprotkb:Q5JYK7|uniprotkb:Q7L124|uniprotkb:Q9UN55|uniprotkb:Q9BUE9|uniprotkb:Q8N0X0|uniprotkb:Q5JYK5|intact:EBI-2802486	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:eci2_human(display_long)|uniprotkb:ECI2(gene name)|psi-mi:ECI2(display_short)|uniprotkb:DRS1(gene name synonym)|uniprotkb:HCA88(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Diazepam-binding inhibitor-related protein 1(gene name synonym)|uniprotkb:DRS-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 88(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-1(gene name synonym)|uniprotkb:PECI(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000198721(gene)|ensembl:ENST00000380118(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:O75521|rcsb pdb:2CQU|rcsb pdb:2F6Q|rcsb pdb:4U18|rcsb pdb:4U19|rcsb pdb:4U1A|reactome:R-HSA-390247|reactome:R-HSA-9033241|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|refseq:NP_001159482.1|refseq:NP_006108.2|refseq:NP_996667.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:AIR8lybsBusmVmjgsN0Hcl6p+3g9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O95905	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UBS4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P25685	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96EY1	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q6IAN0	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-725639|uniprotkb:B5MEF4|uniprotkb:Q6UX59|uniprotkb:Q9BTF9|uniprotkb:Q9UFM6|uniprotkb:Q9Y3A1|ensembl:ENSP00000378887	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:drs7b_human(display_long)|uniprotkb:DHRS7B(gene name)|psi-mi:DHRS7B(display_short)|uniprotkb:SDR32C1(gene name synonym)|uniprotkb:Short-chain dehydrogenase/reductase family 32C member 1(gene name synonym)|uniprotkb:CGI-93(orf name)|uniprotkb:UNQ212/PRO238(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_056325.2|ensembl:ENSG00000109016(gene)|ensembl:ENST00000395511(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-HSA-75896|refseq:NP_001317088.1|refseq:XP_016879915.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:qGu2N6bspgbSJE+AIL0Xeh6b0J49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96DF8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-3928124|uniprotkb:Q49AH7|uniprotkb:Q9BTZ4|ensembl:ENSP00000252137	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ess2_human(display_long)|uniprotkb:ESS2(gene name)|psi-mi:ESS2(display_short)|uniprotkb:DGCR13(gene name synonym)|uniprotkb:DGCR14(gene name synonym)|uniprotkb:DGSH(gene name synonym)|uniprotkb:DGSI(gene name synonym)|uniprotkb:DiGeorge syndrome critical region 13(gene name synonym)|uniprotkb:DiGeorge syndrome critical region 14(gene name synonym)|uniprotkb:DiGeorge syndrome protein H(gene name synonym)|uniprotkb:ES2(gene name synonym)|uniprotkb:Protein ES2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000100056(gene)|ensembl:ENST00000252137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR019148|ensembl:ENSP00000252137|refseq:NP_073210.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:4FNOVEs4KXbqLkXlGksstSsL2qs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P48729	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|intact:EBI-11048253|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|ensembl:ENSP00000367074	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|dip:DIP-40367N|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P53618	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P09543	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1059219|intact:EBI-1188262|ensembl:ENSP00000377470	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cn37_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_149124.3|refseq:XP_011522642.1|ensembl:ENSG00000173786(gene)|ensembl:ENST00000393892(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0045202"(synapse)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P09543|rcsb pdb:1WOJ|go:"GO:0003723"(RNA binding)|refseq:NP_001317145.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:TpzVM789s3qQKK7B00Vo92s31bY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9H078	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5VV42	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O00311	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-374980|uniprotkb:O00558|uniprotkb:Q5T5U5|ensembl:ENSP00000234626|ensembl:ENSP00000393139|uniprotkb:D3DT31	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cdc7_human(display_long)|uniprotkb:CDC7(gene name)|psi-mi:CDC7(display_short)|uniprotkb:CDC7L1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	rcsb pdb:5UWR|rcsb pdb:6YA6|rcsb pdb:6YA7|rcsb pdb:6YA8|reactome:R-HSA-176187|reactome:R-HSA-68962|reactome:R-HSA-8953750|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O00311|rcsb pdb:4F99|rcsb pdb:4F9A|rcsb pdb:4F9B|rcsb pdb:4F9C|rcsb pdb:5UWQ|ensembl:ENSG00000097046(gene)|ensembl:ENST00000234626(transcript)|ensembl:ENST00000428239(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|refseq:NP_001127891.1|refseq:NP_001127892.1|refseq:NP_003494.1|refseq:XP_005271298.1|dip:DIP-31728N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:p5yHRwdn0crHmH8EXAFyM5R0xwM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96A33	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q86VP6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8WWC4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P46379	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P36542	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P10398	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-365961|uniprotkb:P07557|uniprotkb:Q5H9B3|intact:EBI-28988863|ensembl:ENSP00000366244|uniprotkb:Q5H9B2	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:araf_human(display_long)|uniprotkb:ARAF(gene name)|psi-mi:ARAF(display_short)|uniprotkb:PKS(gene name synonym)|uniprotkb:PKS2(gene name synonym)|uniprotkb:ARAF1(gene name synonym)|uniprotkb:Proto-oncogene A-Raf-1(gene name synonym)|uniprotkb:Proto-oncogene Pks(gene name synonym)|uniprotkb:Proto-oncogene A-Raf(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000078061(gene)|ensembl:ENST00000377045(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P10398|rcsb pdb:2MSE|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|rcsb pdb:1WXM|refseq:NP_001645.1|refseq:XP_011542210.1|refseq:NP_001243125.1|ensembl:ENST00000377039|ensembl:ENSP00000366238|ensembl:ENSP00000366244|refseq:NP_001243126.1|dip:DIP-31374N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:WRtbdrEuDxNkA6jRRxvapodFcUE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9C0C7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2512975|ensembl:ENSP00000415327|ensembl:ENSP00000508322|uniprotkb:Q86XD6|uniprotkb:A6XN33|uniprotkb:Q9NXE7|uniprotkb:Q9H8Z0|intact:EBI-2556181|uniprotkb:D3DQP8|uniprotkb:G3V193	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:amra1_human(display_long)|uniprotkb:AMBRA1(gene name)|psi-mi:AMBRA1(display_short)|uniprotkb:DCAF3(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 3(gene name synonym)|uniprotkb:KIAA1736(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000110497(gene)|ensembl:ENST00000458649(transcript)|ensembl:ENST00000683756(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-HSA-1632852|refseq:NP_001287660.1|refseq:NP_060219.2|refseq:NP_001254711.1|refseq:NP_001254712.1|refseq:XP_005253066.1|refseq:XP_005253068.1|refseq:XP_005253071.1|refseq:XP_006718322.1|dip:DIP-53597N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:h4yD2iL711peDzI4kttngSdTLQk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9BT22	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6268721|uniprotkb:B4DP08|ensembl:ENSP00000262374|uniprotkb:Q6UVZ9|uniprotkb:Q8N5Y4|uniprotkb:Q9P2Y2	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:alg1_human(display_long)|uniprotkb:ALG1(gene name)|psi-mi:ALG1(display_short)|uniprotkb:HMAT1(gene name synonym)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 1 homolog(gene name synonym)|uniprotkb:Beta-1,4-mannosyltransferase(gene name synonym)|uniprotkb:"GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase"(gene name synonym)|uniprotkb:GDP-mannose-dolichol diphosphochitobiose mannosyltransferase(gene name synonym)|uniprotkb:Mannosyltransferase-1(gene name synonym)|uniprotkb:PSEC0061(orf name)|uniprotkb:UNQ861/PRO1870(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000033011(gene)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0004578"(chitobiosyldiphosphodolichol beta-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR026051|mint:Q9BT22|reactome:R-HSA-446193|reactome:R-HSA-4549380|ensembl:ENST00000262374(transcript)|refseq:NP_061982.3|refseq:NP_001317433.1|refseq:XP_016878947.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:ssuj2ltO7juusnd1BHWPqAsYdV09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y4W6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8NI60	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P61221	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2510446|ensembl:ENSP00000296577|uniprotkb:Q6NR76|uniprotkb:O88793|uniprotkb:Q13181|uniprotkb:Q99K66|uniprotkb:Q13864|uniprotkb:Q96AL0|uniprotkb:Q96B10	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:abce1_human(display_long)|uniprotkb:ABCE1(gene name)|psi-mi:ABCE1(display_short)|uniprotkb:RLI(gene name synonym)|uniprotkb:RNASEL1(gene name synonym)|uniprotkb:RNASELI(gene name synonym)|uniprotkb:RNS4I(gene name synonym)|uniprotkb:RNase L inhibitor(gene name synonym)|uniprotkb:Ribonuclease 4 inhibitor(gene name synonym)|uniprotkb:2'-5'-oligoadenylate-binding protein(gene name synonym)|uniprotkb:HuHP68(gene name synonym)|uniprotkb:OK/SW-cl.40(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000164163(gene)|ensembl:ENST00000296577(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005506"(iron ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006415"(translational termination)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR017871|interpro:IPR017896|interpro:IPR017900|interpro:IPR027417|interpro:IPR034348|mint:P61221|rcsb pdb:6ZME|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:NP_001035809.1|refseq:NP_002931.2	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:+6ykpRtI4p94M3TuoTzFBvdCsC09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9H992	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-949983|ensembl:ENSP00000386830|ensembl:ENSP00000259050|uniprotkb:Q53GQ1|uniprotkb:Q9BTR9|uniprotkb:A8K9X1|uniprotkb:D3DPB0|uniprotkb:B7Z7P5	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:marh7_human(display_long)|uniprotkb:MARCHF7(gene name)|psi-mi:MARCHF7(display_short)|uniprotkb:AXOT(gene name synonym)|uniprotkb:Axotrophin(gene name synonym)|uniprotkb:MARCH7(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 7(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VII(gene name synonym)|uniprotkb:RING finger protein 177(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF7(gene name synonym)|uniprotkb:RNF177(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001269734.1|refseq:NP_001269735.1|refseq:NP_001269736.1|ensembl:ENST00000259050(transcript)|ensembl:ENST00000409175(transcript)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016740"(transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050821"(protein stabilization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|ensembl:ENSG00000136536(gene)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_073737.1|refseq:XP_005246830.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:HT4KtjhOVdeP4mam5eQhgX+ib5A9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96RT7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2555074|uniprotkb:Q9UGX3|uniprotkb:Q9UGX4|uniprotkb:Q5JZ80|uniprotkb:Q6PJ40|uniprotkb:Q9BY91|uniprotkb:Q86YE9|ensembl:ENSP00000248846	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:gcp6_human(display_long)|uniprotkb:GCP6(gene name synonym)|uniprotkb:KIAA1669(gene name synonym)|uniprotkb:TUBGCP6(gene name)|psi-mi:TUBGCP6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_065194.2|ensembl:ENSG00000128159(gene)|ensembl:ENST00000248846(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|rcsb pdb:6M33|rcsb pdb:6V6C|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:H5Y8PvMXPZTmeJUq8yOQbPZ2jYY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q3ZCQ8	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UNE7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P05141	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q00325	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9H936	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1050588|uniprotkb:Q8TBU8|uniprotkb:A8K366|uniprotkb:C9J1H6|uniprotkb:E9PJD3|uniprotkb:E9PKB2|uniprotkb:E9PL68|uniprotkb:E9PN26|uniprotkb:E9PNQ3|uniprotkb:E9PP01|uniprotkb:E9PR97|ensembl:ENSP00000322020|ensembl:ENSP00000437236|ensembl:ENSP00000486058	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ghc1_human(display_long)|uniprotkb:"Glutamate/H(+) symporter 1"(gene name synonym)|uniprotkb:Solute carrier family 25 member 22(gene name synonym)|uniprotkb:SLC25A22(gene name)|psi-mi:SLC25A22(display_short)|uniprotkb:GC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001177989.1|refseq:NP_001177990.1|refseq:NP_078974.1|ensembl:ENSG00000177542(gene)|ensembl:ENST00000320230(transcript)|ensembl:ENST00000531214(transcript)|ensembl:ENST00000628067(transcript)|go:"GO:0005280"("amino acid:proton symporter activity")|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-428643|refseq:XP_011518671.1|refseq:XP_011518672.1|refseq:XP_011518673.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:B1e6uu3Vx73qy/JrHS7p63p0QMM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UJS0	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75746	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1047585|uniprotkb:Q96AM8|intact:EBI-2802067|uniprotkb:B3KR64|ensembl:ENSP00000388658	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cmc1_human(display_long)|uniprotkb:SLC25A12(gene name)|psi-mi:SLC25A12(display_short)|uniprotkb:ARALAR1(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003696.2|ensembl:ENSG00000115840(gene)|ensembl:ENST00000422440(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:O75746|rcsb pdb:4P5X|rcsb pdb:4P60|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:NMohxjKtV1fhusocdkdQYZ/ng3I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P53007	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005975.1|ensembl:ENSG00000100075(gene)|ensembl:ENST00000215882(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006843"(mitochondrial citrate transmembrane transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015142"(tricarboxylic acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071913"(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:P53007|reactome:R-HSA-70263|reactome:R-HSA-75105	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P63208	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P60468	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O43819	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75880	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-6656171|ensembl:ENSP00000255390|uniprotkb:B2RDM0	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:sco1_human(display_long)|uniprotkb:SCO1(gene name)|psi-mi:SCO1(display_short)|uniprotkb:SCOD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000133028(gene)|ensembl:ENST00000255390(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|rcsb pdb:1WP0|rcsb pdb:2GGT|rcsb pdb:2GQK|rcsb pdb:2GQL|rcsb pdb:2GQM|rcsb pdb:2GT5|rcsb pdb:2GT6|rcsb pdb:2GVP|rcsb pdb:2HRF|rcsb pdb:2HRN|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004580.1|dip:DIP-46086N|refseq:XP_005256808.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:oxGxX5mXuGDP5uPIW1vyOtaQHxU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P57078	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9UPN7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O00743	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P30876	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P08237	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-514788|uniprotkb:Q16814|uniprotkb:Q16815|uniprotkb:J3KNX3|uniprotkb:Q6ZTT1|ensembl:ENSP00000309438|ensembl:ENSP00000352842|ensembl:ENSP00000446945|ensembl:ENSP00000448253|ensembl:ENSP00000449426|ensembl:ENSP00000450369	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pfkam_human(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:PFKM(gene name)|psi-mi:PFKM(display_short)|uniprotkb:6-phosphofructokinase type A(gene name synonym)|uniprotkb:PFKX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_000280.1|refseq:NP_001160158.1|refseq:NP_001160159.1|refseq:NP_001160160.1|refseq:XP_016874957.1|refseq:XP_005269034.1|refseq:XP_005269035.1|refseq:XP_005269036.1|refseq:XP_011536790.1|ensembl:ENSG00000152556(gene)|ensembl:ENST00000312352(transcript)|ensembl:ENST00000359794(transcript)|ensembl:ENST00000547587(transcript)|ensembl:ENST00000550345(transcript)|ensembl:ENST00000550924(transcript)|ensembl:ENST00000551339(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P08237|rcsb pdb:4OMT|reactome:R-HSA-70171	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:tB7V3jdmnyITZLPqyAYjrTWo/UE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O00483	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q15773	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8IYT4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1044332|ensembl:ENSP00000348478|ensembl:ENSP00000508137	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:katl2_human(display_long)|uniprotkb:p60 katanin-like 2(gene name synonym)|uniprotkb:KATNAL2(gene name)|psi-mi:KATNAL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_112593.2|refseq:XP_006722617.1|ensembl:ENSG00000167216(gene)|ensembl:ENST00000356157(transcript)|ensembl:ENST00000683218(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR027417|interpro:IPR027497|interpro:IPR041569	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2k+M09zbS1SB029s47A1CpuD+ZY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q13418	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-747644|uniprotkb:P57043|uniprotkb:Q68DZ3|uniprotkb:B7Z1I0|uniprotkb:D3DQU0|uniprotkb:B7Z418|ensembl:ENSP00000299421|ensembl:ENSP00000379975|ensembl:ENSP00000403487	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:ilk_human(display_long)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:p59ILK(gene name synonym)|uniprotkb:ILK(gene name)|psi-mi:ILK(display_short)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001265370.1|refseq:NP_001014794.1|refseq:NP_001014795.1|refseq:NP_004508.1|refseq:XP_005252961.1|refseq:NP_001265371.1|refseq:XP_005252962.1|refseq:XP_011518367.1|dip:DIP-38657N|rcsb pdb:3IXE|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIB|reactome:R-HSA-446343|reactome:R-HSA-446353|ensembl:ENSG00000166333(gene)|ensembl:ENST00000299421(transcript)|ensembl:ENST00000396751(transcript)|ensembl:ENST00000420936(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|mint:Q13418|rcsb pdb:2KBX|rcsb pdb:3F6Q|go:"GO:0045663"(positive regulation of myoblast differentiation)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:FrK/MsW7IcVWT9VbkHAIVHEh1P89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9Y241	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NWT6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O00165	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q96CS3	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O60762	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:znbNDwp7t238ByanlbQzsTMvwTY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q99615	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O75190	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NXW2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-358818|uniprotkb:Q9H6H0|uniprotkb:B7Z7I3|ensembl:ENSP00000403313	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:djb12_human(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001002762.2|refseq:NP_060096.3|ensembl:ENSG00000148719(gene)|ensembl:ENST00000444643(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|mint:Q9NXW2|rcsb pdb:2CTP|go:"GO:0005789"(endoplasmic reticulum membrane)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:kt+aES6+wgXo7o1UhFt4E5w9wTs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:O60884	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P31689	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q00587	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-744130|uniprotkb:Q96GN1|uniprotkb:A8K825|ensembl:ENSP00000249014	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:borg5_human(display_long)|uniprotkb:Binder of Rho GTPases 5(gene name synonym)|uniprotkb:Serum protein MSE55(gene name synonym)|uniprotkb:CEP1(gene name synonym)|uniprotkb:MSE55(gene name synonym)|uniprotkb:CDC42EP1(gene name)|psi-mi:CDC42EP1(display_short)|uniprotkb:BORG5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_689449.1|refseq:XP_006724170.1|refseq:XP_006724171.1|refseq:XP_006724172.1|ensembl:ENSG00000128283(gene)|ensembl:ENST00000249014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR029273|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|refseq:XP_016884030.1	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:Ros/Dvfb6rdmhUyT755WtSswQjQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q16543	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P50990	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P49368	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P78371	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P27708	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q5T9A4	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:2W52iPQhTBU2apShm8xhfenV1mU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q9NVI7	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:IZKJEVLLS/DFINgBgO5frizN1P49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q53H12	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-2269837|uniprotkb:Q75KN1|uniprotkb:Q96GC3|uniprotkb:Q9NP48|ensembl:ENSP00000496789|ensembl:ENSP00000497280|ensembl:ENSP00000498112|ensembl:ENSP00000458417	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:agk_human(display_long)|uniprotkb:AGK(gene name)|psi-mi:AGK(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:Multiple substrate lipid kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:XP_011514699.1|refseq:NP_060708.1|ensembl:ENSG00000006530(gene)|ensembl:ENST00000575872(transcript)|ensembl:ENST00000648068(transcript)|ensembl:ENST00000649286(transcript)|ensembl:ENST00000650547(transcript)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0001729"(ceramide kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047620"(acylglycerol kinase activity)|go:"GO:0102773"(dihydroceramide kinase activity)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|go:"GO:0005743"(mitochondrial inner membrane)|ensembl:ENSG00000262327(gene)|rcsb pdb:7CGP|reactome:R-HSA-1483206|reactome:R-HSA-6802952|mint:Q53H12	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P28288	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:Q8N490-2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10769878|ensembl:ENSP00000248451	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:q8n490-2(display_long)|uniprotkb:PNKD(gene name)|psi-mi:PNKD(display_short)|uniprotkb:KIAA1184(gene name synonym)|uniprotkb:MR1(gene name synonym)|uniprotkb:TAHCCP2(gene name synonym)|uniprotkb:Myofibrillogenesis regulator 1(gene name synonym)|uniprotkb:Paroxysmal nonkinesiogenic dyskinesia protein(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 2(gene name synonym)|uniprotkb:FKSG19(orf name)|uniprotkb:UNQ2491/PRO5778(orf name)|uniprotkb:MR-1S(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000127838(gene)|ensembl:ENST00000248451(transcript)|intact:EBI-746368(isoform-parent)|uniprotkb:Q8N490-2(isoform-parent)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:cpTDxscb3w5klM/N5tkYzkkJcI89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:P48730-2	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-9087876|ensembl:ENSP00000376146	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent)	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P57078	uniprotkb:H3BN98	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-10977767|ensembl:ENSP00000454746	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:h3bn98_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12503575|imex:IM-22750-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	ensembl:ENSG00000260342(gene)|ensembl:ENST00000567078(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000630(Ribosomal protein S8)|interpro:IPR035987	-	-	-	figure legend:Table S3|comment:"The following preys were not recorded in the entry, as they could not be unambiguously identified: TUBG1,TUBG2 (UniProtKB accessions: P23258;Q9NRH3); GLUD1,GLUD2 (UniProtKB accessions: P00367;P49448); HLA-B (UniProtKB accessions: P01889;P30480;P30492;P30493;P30495;Q29718;Q29836;Q31610); HSP90AB1,HSP90AB3P (UniProtKB accessions: P08238;Q58FF7); ACTC1,ACTA1,ACTA2,ACTG2 (UniProtKB accessions: P62736;P63267;P68032;P68133); APLP2,APP (UniProtKB accessions: P05067;Q06481); CBWD6,CBWD3,CBWD5,CBWD2,CBWD1,CBWD7 (UniProtKB accessions: A6NM15;Q4V339;Q5JTY5;Q5RIA9;Q8IUF1;Q9BRT8); HIST1H2AB,HIST3H2A,HIST1H2AC (UniProtKB accessions: P04908;Q7L7L0;Q93077); MST4,STK24 (UniProtKB accessions: Q9P289;Q9Y6E0); NR2F1,NR2F2 (UniProtKB accessions: P10589;P24468); PPP2CA,PPP2CB (UniProtKB accessions: P62714;P67775); PRPS1,PRPS2,PRPS1L1 (UniProtKB accessions: P11908;P21108;P60891); SEPT11,SEPT8,SEPT6 (UniProtKB accessions: Q14141;Q92599;Q9NVA2); TIMM23,TIMM23B (UniProtKB accessions: O14925;Q5SRD1); TUBA1A,TUBA1C,TUBA3C,TUBA3E (UniProtKB accessions: Q13748;Q6PEY2;Q71U36;Q9BQE3); ZNF167,ZNF658B,ZNF397 (UniProtKB accessions: Q4V348;Q8NF99;Q9P0L1); ZNF195,ZNF677,ZNF253,ZNF713 (UniProtKB accessions: O14628;O75346;Q86XU0;Q8N859)."|comment:"HC preys were selected testing different conditions (DMOG treatment, co-expression with FIH and comparison between those two). Preys selected had a ttest p-value <0.01 AND ratio>2 over the control in at least one of the conditions."|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2021/06/18	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:fDimE+pwgd8trkWNk8fV9qRksrc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q16665	uniprotkb:Q9H6Z9	intact:EBI-447269|uniprotkb:Q53XP6|uniprotkb:Q96PT9|uniprotkb:Q9UPB1|uniprotkb:C0LZJ3|ensembl:ENSP00000338018	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	psi-mi:hif1a_human(display_long)|uniprotkb:ARNT-interacting protein(gene name synonym)|uniprotkb:Member of PAS protein 1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)|uniprotkb:HIF1A(gene name)|psi-mi:HIF1A(display_short)|uniprotkb:MOP1(gene name synonym)|uniprotkb:BHLHE78(gene name synonym)|uniprotkb:PASD8(gene name synonym)|uniprotkb:PAS domain-containing protein 8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym)	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504216|imex:IM-22750-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230013.1|refseq:NP_001521.1|refseq:NP_851397.1|ensembl:ENST00000323441|ensembl:ENSP00000323326|ensembl:ENSP00000338018|ensembl:ENST00000539097|ensembl:ENSP00000437955|dip:DIP-29722N|ensembl:ENSG00000100644(gene)|ensembl:ENST00000337138(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q16665|rcsb pdb:1D7G|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1L3E|rcsb pdb:1L8C|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:2ILM|rcsb pdb:3HQR|rcsb pdb:3HQU|rcsb pdb:4AJY|rcsb pdb:4H6J|rcsb pdb:5JWP|rcsb pdb:5L9B|rcsb pdb:5L9V|rcsb pdb:5LA9|rcsb pdb:5LAS|rcsb pdb:6GFX|rcsb pdb:6GMR|rcsb pdb:6YW3|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|reactome:R-HSA-2122947|reactome:R-HSA-400253|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8849473|reactome:R-HSA-8857538|reactome:R-HSA-8951664	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	-	-	-	figure legend:1E|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:3XRt8HFMCRlxcYR2KfuFSq6gVBg9606	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rigid:lDFCZkP6zOBbloc36oSOS7j326Q	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P57078	uniprotkb:Q9NWT6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504243|imex:IM-22750-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:5B|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:9qh9vhegW9RGTOzeTy53zmhSjDU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16659	uniprotkb:Q7Z6Z7	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504254|imex:IM-22750-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N	-	-	-	figure legend:6B|agonist:"1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935) (PMID:    21372172)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606	rigid:I775mwZtcVndKLpAapH5sK4La9s	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16659	uniprotkb:Q05086	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504254|imex:IM-22750-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1	-	-	-	figure legend:6B|agonist:"1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935) (PMID:    21372172)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606	rigid:I775mwZtcVndKLpAapH5sK4La9s	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16659	uniprotkb:P54727	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504254|imex:IM-22750-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N	-	-	-	figure legend:6B|agonist:"1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935) (PMID:    21372172)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606	rigid:I775mwZtcVndKLpAapH5sK4La9s	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P57078	uniprotkb:Q9NWT6	intact:EBI-4422308|uniprotkb:Q96KH0|ensembl:ENSP00000330161	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:ripk4_human(display_long)|uniprotkb:RIPK4(gene name)|psi-mi:RIPK4(display_short)|uniprotkb:ANKRD3(gene name synonym)|uniprotkb:DIK(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 3(gene name synonym)|uniprotkb:PKC-delta-interacting protein kinase(gene name synonym)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504233|imex:IM-22750-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40722N|ensembl:ENSG00000183421(gene)|ensembl:ENST00000352483(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:1jgoEgfCkjhbVu3jpg/+ZHroZyM9606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:9qh9vhegW9RGTOzeTy53zmhSjDU	false	flag tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H6Z9	uniprotkb:Q16659	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504267|imex:IM-22750-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	-	-	-	figure legend:6C|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rigid:PLGQGBUZ7Kmuna1FWnKWdKIoOcc	false	v5 tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H6Z9	uniprotkb:Q16659	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504304|imex:IM-22750-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	-	-	-	figure legend:7G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rigid:PLGQGBUZ7Kmuna1FWnKWdKIoOcc	false	v5 tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H6Z9	uniprotkb:Q16659	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504290|imex:IM-22750-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	-	-	-	figure legend:6D|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rigid:PLGQGBUZ7Kmuna1FWnKWdKIoOcc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6Z9	uniprotkb:Q16659	intact:EBI-1175354|uniprotkb:Q2TA79|uniprotkb:Q3B8N4|uniprotkb:Q6P1R2|ensembl:ENSP00000250457	intact:EBI-1384105|uniprotkb:Q68DH4|uniprotkb:Q8IYN8|uniprotkb:B2R945|uniprotkb:B5BU65|ensembl:ENSP00000261845|ensembl:ENSP00000505601|ensembl:ENSP00000505862|ensembl:ENSP00000506036|ensembl:ENSP00000506184	psi-mi:egln3_human(display_long)|uniprotkb:Hypoxia-inducible factor prolyl hydroxylase 3(gene name synonym)|uniprotkb:HPH-1(gene name synonym)|uniprotkb:Prolyl hydroxylase domain-containing protein 3(gene name synonym)|uniprotkb:EGLN3(gene name)|psi-mi:EGLN3(display_short)|uniprotkb:Egl nine homolog 3(gene name synonym)	psi-mi:mk06_human(display_long)|uniprotkb:ERK3(gene name synonym)|uniprotkb:PRKM6(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 3(gene name synonym)|uniprotkb:MAP kinase isoform p97(gene name synonym)|uniprotkb:MAPK6(gene name)|psi-mi:MAPK6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Rodriguez et al. (2016)	pubmed:26972000|imex:IM-22750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12504297|imex:IM-22750-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|mint:Q9H6Z9|reactome:R-HSA-1234176|ensembl:ENSG00000129521(gene)|ensembl:ENST00000250457(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_071356.1|refseq:NP_001295032.1	refseq:XP_011520084.1|refseq:NP_002739.1|refseq:XP_005254594.1|refseq:XP_005254595.1|refseq:XP_005254596.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|ensembl:ENSG00000069956(gene)|ensembl:ENST00000261845(transcript)|ensembl:ENST00000680066(transcript)|ensembl:ENST00000680652(transcript)|ensembl:ENST00000680777(transcript)|ensembl:ENST00000681888(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008350(ERK3/4 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6YKY|rcsb pdb:6YLC|rcsb pdb:6YLL|rcsb pdb:7AQB|reactome:R-HSA-5687128	-	-	-	figure legend:6E|agonist:"DMOG (CHEBI:102218)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/06/27	2016/08/10	rogid:qkcZeQzvxL+8efCa0kakLjwXDt89606	rogid:Gek79ujQv6Xznswv4ZIxXbgX4OE9606	rigid:PLGQGBUZ7Kmuna1FWnKWdKIoOcc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)