#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P52926 uniprotkb:P16104 intact:EBI-912511|uniprotkb:Q1M182|uniprotkb:E7EP85|uniprotkb:E7EWA2|uniprotkb:Q1M185|uniprotkb:Q1M186|uniprotkb:Q1M187|uniprotkb:Q1M188|ensembl:ENSP00000384026 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:hmga2_human(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short)|uniprotkb:HMGIC(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9990174|imex:IM-23312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003474.1|refseq:NP_003475.1|refseq:NP_001317119.1|ensembl:ENSG00000149948(gene)|ensembl:ENST00000403681(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009615"(response to virus)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|reactome:R-HSA-2559584 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - - figure legend:Fig. B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/11/25 2014/11/26 rogid:J6xNJMDK/cdxNB9cX7Ey2NIlaUo9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 intact-crc:C90C8C6DEFF9E09D|rigid:Cy1RiP86/Htygwirk9J6U5lculo false - N-phosphorylated residue:140-140 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52926 uniprotkb:Q13315 intact:EBI-912511|uniprotkb:Q1M182|uniprotkb:E7EP85|uniprotkb:E7EWA2|uniprotkb:Q1M185|uniprotkb:Q1M186|uniprotkb:Q1M187|uniprotkb:Q1M188|ensembl:ENSP00000384026 intact:EBI-495465|uniprotkb:O15429|uniprotkb:Q12758|uniprotkb:Q16551|uniprotkb:Q93007|uniprotkb:Q9NP02|uniprotkb:Q9UCX7|intact:EBI-1059333|uniprotkb:B2RNX5|intact:EBI-28985245|ensembl:ENSP00000278616|ensembl:ENSP00000388058|ensembl:ENSP00000501606 psi-mi:hmga2_human(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short)|uniprotkb:HMGIC(gene name synonym) psi-mi:atm_human(display_long)|uniprotkb:ATM(gene name)|psi-mi:ATM(display_short)|uniprotkb:Ataxia telangiectasia mutated(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9990174|imex:IM-23312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003474.1|refseq:NP_003475.1|refseq:NP_001317119.1|ensembl:ENSG00000149948(gene)|ensembl:ENST00000403681(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009615"(response to virus)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|reactome:R-HSA-2559584 refseq:NP_000042.3|refseq:XP_011541142.1|ensembl:ENSP00000501606|ensembl:ENSP00000278616|ensembl:ENSP00000388058|refseq:XP_005271618.2|refseq:XP_005271619.2|refseq:XP_006718906.1|refseq:XP_006718908.1|dip:DIP-182N|refseq:XP_016873278.1|refseq:XP_016873279.1|ensembl:ENSG00000149311(gene)|ensembl:ENST00000452508(transcript)|ensembl:ENST00000675843(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0002331"(pre-B cell allelic exclusion)|go:"GO:0003677"(DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007165"(signal transduction)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0097694"(establishment of RNA localization to telomere)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904354"(negative regulation of telomere capping)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904884"(positive regulation of telomerase catalytic core complex assembly)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR015519(Ataxia-Telangiectasia Mutated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR044107|ensembl:ENST00000278616(transcript)|mint:Q13315|rcsb pdb:5NP0|rcsb pdb:5NP1|rcsb pdb:6HKA|rcsb pdb:6K9K|rcsb pdb:6K9L|reactome:R-HSA-2559586|reactome:R-HSA-3371453|reactome:R-HSA-349425|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803207|reactome:R-HSA-6804756|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-912446|reactome:R-HSA-9664873|reactome:R-HSA-6804757 - - - figure legend:Fig. B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/11/25 2014/11/26 rogid:J6xNJMDK/cdxNB9cX7Ey2NIlaUo9606 rogid:d/FYo7KdBblfR/inXUZpFlWTfoo9606 intact-crc:C90C8C6DEFF9E09D|rigid:Cy1RiP86/Htygwirk9J6U5lculo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52927 uniprotkb:P27661 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-495621|ensembl:ENSMUSP00000051432 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h2ax_mouse(display_long)|uniprotkb:H2ax(gene name)|psi-mi:H2ax(display_short)|uniprotkb:H2a.x(gene name synonym)|uniprotkb:H2afx(gene name synonym)|uniprotkb:Hist5-2ax(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034566.1|ensembl:ENSMUSG00000049932(gene)|ensembl:ENSMUST00000052686(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P27661|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|reactome:R-MMU-5693607 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Z1pmQt/GCyjkaDs6Ot8O7Cc8rAM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CWZ3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1993805|uniprotkb:Q9D6U5|uniprotkb:Q3UT38|uniprotkb:Q6GTD4|uniprotkb:A0A023T672|ensembl:ENSMUSP00000143190 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rbm8a_mouse(display_long)|uniprotkb:Rbm8a(gene name)|psi-mi:Rbm8a(display_short)|uniprotkb:Rbm8(gene name synonym)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001095877.1|refseq:NP_080151.2|ensembl:ENSMUSG00000038374(gene)|ensembl:ENSMUST00000196456(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9CWZ3|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VDD9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1369766|uniprotkb:Q9ESL6|uniprotkb:Q3TS96|uniprotkb:Q80VI6|uniprotkb:Q9EPY1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:phip_mouse(display_long)|uniprotkb:Phip1(gene name synonym)|uniprotkb:Phip(gene name)|psi-mi:Phip(display_short)|uniprotkb:Wdr11(gene name synonym)|uniprotkb:Ndrp(gene name synonym)|uniprotkb:IRS-1 PH domain-binding protein(gene name synonym)|uniprotkb:WD repeat-containing protein 11(gene name synonym)|uniprotkb:Neuronal differentiation-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR028738|interpro:IPR036322|interpro:IPR036427|mint:Q8VDD9|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|reactome:R-MMU-9013418 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Q3tjNzPTobuShNidgEYMDlV04s010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R0N0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3870529|intact:EBI-8362283|intact:MINT-4129760|uniprotkb:Q9JIA6|ensembl:ENSMUSP00000021114 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:galk1_mouse(display_long)|uniprotkb:Galk1(gene name)|psi-mi:Galk1(display_short)|uniprotkb:Galk(gene name synonym)|uniprotkb:Glk(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_058601.2|ensembl:ENSMUSG00000020766(gene)|ensembl:ENSMUST00000021114(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0033499"(galactose catabolic process via UDP-galactose)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0061623"(glycolytic process from galactose)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:Q9R0N0|reactome:R-MMU-70370 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4kVUQtJtkIYvnEpR581pKry69aE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922H2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3870603|uniprotkb:Q8BTX1|ensembl:ENSMUSP00000036604 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pdk3_mouse(display_long)|uniprotkb:Pdk3(gene name)|psi-mi:Pdk3(display_short)|uniprotkb:Pyruvate dehydrogenase kinase isoform 3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_663605.1|ensembl:ENSMUSG00000035232(gene)|ensembl:ENSMUST00000045748(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|reactome:R-MMU-204174|reactome:R-MMU-5362517 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:n/j1wzbhIDqSHyiqMbYarA9l9EE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WVK4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8321414|intact:MINT-1863155|ensembl:ENSMUSP00000025684 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ehd1_mouse(display_long)|uniprotkb:Ehd1(gene name)|psi-mi:Ehd1(display_short)|uniprotkb:Past1(gene name synonym)|uniprotkb:PAST homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034249.1|dip:DIP-59491N|ensembl:ENSMUSG00000024772(gene)|ensembl:ENSMUST00000025684(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9WVK4|reactome:R-MMU-983231 - - comment:mint|function:Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6eI3lDw0K5kWK6+oxA8kBTDydHs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P13439 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8319201|intact:MINT-1852291|uniprotkb:Q99L26|ensembl:ENSMUSP00000023510 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:umps_mouse(display_long)|uniprotkb:Umps(gene name)|psi-mi:Umps(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033497.1|ensembl:ENSMUSG00000022814(gene)|ensembl:ENSMUST00000023510(transcript)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006222"(UMP biosynthetic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR018089|interpro:IPR023031|interpro:IPR029057|mint:P13439|reactome:R-MMU-500753 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:9ehavUfU08jtjA7KVHz2evDLV3Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99KG5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8077034|uniprotkb:Q6U816|uniprotkb:Q61149|intact:UNK-5536706|uniprotkb:Q61148|uniprotkb:Q3UIQ9|uniprotkb:Q3TJE7|ensembl:ENSMUSP00000001279|ensembl:ENSMUSP00000146120 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:lsr_mouse(display_long)|uniprotkb:Lsr(gene name)|psi-mi:Lsr(display_short)|uniprotkb:Lisch7(gene name synonym)|uniprotkb:Liver-specific bHLH-Zip transcription factor(gene name synonym)|uniprotkb:Lipolysis-stimulated receptor(gene name synonym)|uniprotkb:Liver-specific gene on mouse chromosome 7 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001157656.1|refseq:NP_001157657.1|refseq:NP_059101.1|ensembl:ENSMUSG00000001247(gene)|ensembl:ENSMUST00000001279(transcript)|ensembl:ENSMUST00000205961(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0042627"(chylomicron)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0060856"(establishment of blood-brain barrier)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:1904274"(tricellular tight junction assembly)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR008664(LISCH7)|interpro:IPR036179 - - comment:mint|comment:homomint|function:Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QJgx6EbqrlzaNElEzUqNhiCol6A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6ZWQ9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8034418|intact:UNK-5490476|ensembl:ENSMUSP00000024846|ensembl:ENSMUSP00000116398|ensembl:ENSMUSP00000123412|ensembl:ENSMUSP00000156508|ensembl:ENSMUSP00000156522|ensembl:ENSMUSP00000156594|ensembl:ENSMUSP00000156693 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q6zwq9_mouse(display_long)|uniprotkb:Myl12a(gene name)|psi-mi:Myl12a(display_short)|uniprotkb:2900073G15Rik(gene name synonym)|uniprotkb:Myl12b(gene name synonym)|uniprotkb:Gm49909(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080340.2|ensembl:ENSMUSG00000024048(gene)|ensembl:ENSMUSG00000117098(gene)|ensembl:ENSMUST00000024846(transcript)|ensembl:ENSMUST00000123686(transcript)|ensembl:ENSMUST00000148960(transcript)|ensembl:ENSMUST00000232766(transcript)|ensembl:ENSMUST00000233089(transcript)|ensembl:ENSMUST00000233417(transcript)|ensembl:ENSMUST00000233798(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247 - - comment:mint|comment:homomint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4E6Q/Ilwmfu3aaQ8ArPbEd6jCYs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P24547 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8317637|uniprotkb:Q61734|intact:MINT-1869864|uniprotkb:Q91Z11|ensembl:ENSMUSP00000079888 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:imdh2_mouse(display_long)|uniprotkb:Impdh2(gene name)|psi-mi:Impdh2(display_short)|uniprotkb:IMPDH-II(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035960.2|ensembl:ENSMUSG00000062867(gene)|ensembl:ENSMUST00000081111(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P24547|reactome:R-MMU-6798695|reactome:R-MMU-73817 - - function:Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vLz8hMd9Q8xsT5bB5QlmxCRIXQE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P61222 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8313100|ensembl:ENSMUSP00000079379|uniprotkb:Q13181|uniprotkb:Q96AL0|uniprotkb:Q96B10|uniprotkb:O88793|intact:MINT-1870092|uniprotkb:Q13864|uniprotkb:Q99K66 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:abce1_mouse(display_long)|uniprotkb:Abce1(gene name)|psi-mi:Abce1(display_short)|uniprotkb:Rli(gene name synonym)|uniprotkb:RNase L inhibitor(gene name synonym)|uniprotkb:Ribonuclease 4 inhibitor(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006415"(translational termination)|go:"GO:0006417"(regulation of translation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR017871|interpro:IPR017896|interpro:IPR017900|interpro:IPR027417|go:"GO:0005739"(mitochondrion)|interpro:IPR034348|reactome:R-MMU-8983711|reactome:R-MMU-909733|mint:P61222|ensembl:ENSMUSG00000058355(gene)|ensembl:ENSMUST00000080536(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005506"(iron ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_056566.2 - - comment:mint|function:"Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+6ykpRtI4p94M3TuoTzFBvdCsC010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O70492 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8315890|intact:MINT-4135125 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:snx3_mouse(display_long)|uniprotkb:Snx3(gene name)|psi-mi:Snx3(display_short)|uniprotkb:SDP3 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0010008"(endosome membrane)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010324"(membrane invagination)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030904"(retromer complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0033572"(transferrin transport)|go:"GO:0034499"(late endosome to Golgi transport)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1905394"(retromer complex binding)|go:"GO:2000642"(negative regulation of early endosome to late endosome transport)|reactome:R-MMU-3238698|reactome:R-MMU-5689880|mint:O70492|interpro:IPR036871|interpro:IPR042137|interpro:IPR001683(Phox-like) - - comment:mint|function:May be involved in several stages of intracellular trafficking figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RAgszsrvQ0Uh/U3HEG1dPmJzu2A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922D8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8316499|ensembl:ENSMUSP00000021443|intact:MINT-1856310|uniprotkb:Q8R013 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:c1tc_mouse(display_long)|uniprotkb:Mthfd1(gene name)|psi-mi:Mthfd1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000021048(gene)|ensembl:ENSMUST00000021443(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004477"(methenyltetrahydrofolate cyclohydrolase activity)|go:"GO:0004486"("methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity")|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009069"(serine family amino acid metabolic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0061053"(somite development)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|go:"GO:0007507"(heart development)|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|mint:Q922D8|reactome:R-MMU-196757|refseq:NP_620084.2 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5mhsOKMWX4yCn5OZpAcw9fpf8ac10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R0A0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8384139|intact:MINT-4107217|ensembl:ENSMUSP00000099506 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pex14_mouse(display_long)|uniprotkb:Pex14(gene name)|psi-mi:Pex14(display_short)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)|uniprotkb:Peroxin-14(gene name synonym)|uniprotkb:PTS1 receptor-docking protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062755.1|ensembl:ENSMUSG00000028975(gene)|ensembl:ENSMUST00000103217(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036250"(peroxisome transport along microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044721"(protein import into peroxisome matrix, substrate release)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:Q9R0A0|reactome:R-MMU-8866654|reactome:R-MMU-9033241|reactome:R-MMU-9603798 - - function:Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AekrsTGdgaqOcuQxsGp0iK5ZSB010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9ET54 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8377991|intact:MINT-4129416|uniprotkb:A0JNZ3|uniprotkb:Q9CWW1|uniprotkb:Q6DFX7|uniprotkb:Q69ZT7|ensembl:ENSMUSP00000112442 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:palld_mouse(display_long)|uniprotkb:Palld(gene name)|psi-mi:Palld(display_short)|uniprotkb:Kiaa0992(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001280701.1|refseq:NP_001280703.1|refseq:XP_011240544.1|refseq:NP_001074859.1|refseq:XP_006509566.1|ensembl:ENSMUSG00000058056(gene)|ensembl:ENSMUST00000121785(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031529"(ruffle organization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033017|interpro:IPR036179|mint:Q9ET54|rcsb pdb:2LQR - - comment:mint|function:Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific May be required for the initiation of neural tube closure figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:U4Q2JIpuBZSxWr1tjjUvog+p4OI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CZH3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8586005|ensembl:ENSMUSP00000031531|ensembl:ENSMUSP00000138161|intact:MINT-8178445 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psmg3_mouse(display_long)|uniprotkb:Psmg3(gene name)|psi-mi:Psmg3(display_short)|uniprotkb:Pac3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000029551(gene)|ensembl:ENSMUST00000031531(transcript)|ensembl:ENSMUST00000182602(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR018788|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_079880.1|refseq:XP_006504789.1 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:2LZEnpyzUWHmOfdR9IS0s3r2bC810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P58466 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7091612|ensembl:ENSMUSP00000027367|intact:UNK-5381027 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ctds1_mouse(display_long)|uniprotkb:Ctdsp1(gene name)|psi-mi:Ctdsp1(display_short)|uniprotkb:Nif3(gene name synonym)|uniprotkb:Nliif(gene name synonym)|uniprotkb:Small C-terminal domain phosphatase 1(gene name synonym)|uniprotkb:Nuclear LIM interactor-interacting factor 3(gene name synonym)|uniprotkb:Golli-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000026176(gene)|ensembl:ENSMUST00000027367(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|interpro:IPR036412|interpro:IPR040078|refseq:NP_694728.1 - - comment:mint|comment:homomint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Fktsb63FTxU8RUQJDKU7J+Tn35A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P59235 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8460031|intact:MINT-4104279|uniprotkb:E9QPN3|ensembl:ENSMUSP00000046732 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nup43_mouse(display_long)|uniprotkb:Nup43(gene name)|psi-mi:Nup43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_663752.2|ensembl:ENSMUSG00000040034(gene)|ensembl:ENSMUST00000040135(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:P59235|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025 - - comment:mint|function:May mediate the assembly of subdomains of the NPC or facilitate the interaction of transport complexes with the NPC figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:w3Xce/jXFL8Qoghmmrisa0M+FL010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JLB2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7352463|intact:MINT-1206544|ensembl:ENSMUSP00000080683 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pals1_mouse(display_long)|uniprotkb:Pals1(gene name)|psi-mi:Pals1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:Mpp5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062525.1|ensembl:ENSMUSG00000021112(gene)|ensembl:ENSMUST00000082024(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0010467"(gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045177"(apical part of cell)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q9JLB2|rcsb pdb:1VA8|rcsb pdb:1VF6|refseq:XP_006516160.1 - - comment:mint|function:May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of VIL2 to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:YJ2sctzj4kgFJL0xae5I75lOHcc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D819 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8317147|intact:MINT-4098757|ensembl:ENSMUSP00000020286 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ipyr_mouse(display_long)|uniprotkb:Ppa1(gene name)|psi-mi:Ppa1(display_short)|uniprotkb:Pp(gene name synonym)|uniprotkb:Pyp(gene name synonym)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080714.2|ensembl:ENSMUSG00000020089(gene)|ensembl:ENSMUST00000020286(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0016462"(pyrophosphatase activity)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q9D819|reactome:R-MMU-379716|reactome:R-MMU-71737 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/YfCFmTO8C51+0zxF3vFnSXcXQs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P09542 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8345052|intact:MINT-4102127|uniprotkb:Q9CQZ2|uniprotkb:Q3UIF4|ensembl:ENSMUSP00000078715 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:myl3_mouse(display_long)|uniprotkb:Myl3(gene name)|psi-mi:Myl3(display_short)|uniprotkb:Mlc1v(gene name synonym)|uniprotkb:Mylc(gene name synonym)|uniprotkb:Myosin light chain 1, slow-twitch muscle B/ventricular isoform(gene name synonym)|uniprotkb:Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034989.1|ensembl:ENSMUSG00000059741(gene)|ensembl:ENSMUST00000079784(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P09542|reactome:R-MMU-390522 - - function:Regulatory light chain of myosin. Does not bind calcium|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:DB1L8qtOO7ASQnr//L+ith93jOo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BM55 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8380674|uniprotkb:Q3TLH3|intact:MINT-4119367|uniprotkb:Q8VC05|uniprotkb:Q78HK3|uniprotkb:Q8R0D5|uniprotkb:Q3UPX9|uniprotkb:Q8R237|ensembl:ENSMUSP00000144615 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tm214_mouse(display_long)|uniprotkb:Tmem214(gene name)|psi-mi:Tmem214(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_653108.2|refseq:XP_006504153.1|refseq:XP_017176576.1|ensembl:ENSMUSG00000038828(gene)|ensembl:ENSMUST00000201203(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019308|mint:Q8BM55 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PadmMtQmAn4Lsk1KaHyyvMKOAV410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91WK0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7996195|uniprotkb:Q9CU89|uniprotkb:Q8BVD1|intact:MINT-5102469 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:lrrf2_mouse(display_long)|uniprotkb:Lrrfip2(gene name)|psi-mi:Lrrfip2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR019139|refseq:NP_082018.1|refseq:NP_001158310.1|mint:Q91WK0|go:"GO:0002756"(MyD88-independent toll-like receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035660"(MyD88-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity) - - comment:mint|function:May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oDgIYHLW2PlrYk0pvnqMRhdnG1U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q78XF5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8340257|uniprotkb:Q9CPZ2|intact:MINT-4124750|ensembl:ENSMUSP00000046480 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ostc_mouse(display_long)|uniprotkb:Ostc(gene name)|psi-mi:Ostc(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079785.1|ensembl:ENSMUSG00000041084(gene)|ensembl:ENSMUST00000043937(transcript)|go:"GO:0006486"(protein glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR021149|interpro:IPR042416|mint:Q78XF5 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WoEvIbU0/LDlRpxPkdZwI2szaIE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9ERS5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8079166|intact:MINT-1773601|uniprotkb:Q8BY29|ensembl:ENSMUSP00000066546|ensembl:ENSMUSP00000122564 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pkha2_mouse(display_long)|uniprotkb:Plekha2(gene name)|psi-mi:Plekha2(display_short)|uniprotkb:Tapp2(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 2(gene name synonym)|uniprotkb:PH domain-containing adaptor PHAD47(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_112547.1|refseq:XP_006509290.1|refseq:XP_006509291.1|refseq:XP_006509293.1|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1V5P|reactome:R-MMU-1660499|ensembl:ENSMUSG00000031557(gene)|ensembl:ENSMUST00000064883(transcript)|ensembl:ENSMUST00000128715(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding) - - comment:mint|function:"Binds specifically to phosphatidylinositol-3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BBxt65RN6h4ceXnNpJe4oUz6jzA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80YV2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8458917|uniprotkb:Q80Z11|uniprotkb:Q3TJE6|uniprotkb:Q8R3U7|uniprotkb:Q8CI56|uniprotkb:Q8BTW5|intact:MINT-4112467|ensembl:ENSMUSP00000079627 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nipa_mouse(display_long)|uniprotkb:Zc3hc1(gene name)|psi-mi:Zc3hc1(display_short)|uniprotkb:Nipa(gene name synonym)|uniprotkb:Nuclear-interacting partner of anaplastic lymphoma kinase(gene name synonym)|uniprotkb:Zinc finger C3HC-type protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_766323.1|refseq:NP_001298015.1|refseq:XP_017177060.1|ensembl:ENSMUSG00000039130(gene)|ensembl:ENSMUST00000080812(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051301"(cell division)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR012935(Zinc finger, C3HC-like)|interpro:IPR013909(mRNA export, Rsm1-like)|mint:Q80YV2 - - comment:mint|function:"Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry (By similarity). Overexpression may be able to protect from apoptosis induced by IL-3 withdrawal" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Oof53JrNMhcVPnAE+d4UVV2A2PA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JJE7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8439959|intact:MINT-4114355|uniprotkb:Q8CDZ4|uniprotkb:Q8C4Y5|uniprotkb:Q7TND7|ensembl:ENSMUSP00000111659 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:fads3_mouse(display_long)|uniprotkb:Fads3(gene name)|psi-mi:Fads3(display_short)|uniprotkb:"Delta(13) fatty acid desaturase"(gene name synonym)|uniprotkb:MNCb-0629(orf name) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_068690.3|ensembl:ENSMUSG00000024664(gene)|ensembl:ENSMUST00000115995(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR001199(Cytochrome b5)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR012171(Fatty acid/sphingolipid desaturase)|interpro:IPR036400|mint:Q9JJE7 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:xXeweCfjqbvaJ3usKvLBAdgaJHo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQT2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8373045|intact:MINT-4131940|uniprotkb:Q7TQE3|uniprotkb:Q3UB91|ensembl:ENSMUSP00000126374 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rbm7_mouse(display_long)|uniprotkb:Rbm7(gene name)|psi-mi:Rbm7(display_short)|uniprotkb:RNA-binding motif protein 7(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_659197.2|ensembl:ENSMUSG00000042396(gene)|ensembl:ENSMUST00000170000(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9CQT2 - - comment:mint|function:Possible involved in germ cell RNA processing and meiosis figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+IPZJDfLW3o1zHvN4RkBx+Phw6o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P27600 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8351154|intact:MINT-4096224|ensembl:ENSMUSP00000000153 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gna12_mouse(display_long)|uniprotkb:Gna12(gene name)|psi-mi:Gna12(display_short)|uniprotkb:Gna-12(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034432.1|ensembl:ENSMUSG00000000149(gene)|ensembl:ENSMUST00000000153(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P27600|rcsb pdb:1ZCA|reactome:R-MMU-416482|reactome:R-MMU-456926 - - comment:mint|function:"Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ODrhvo04jIj7kVE2Vgss4O+X+f010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P11031 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8338874|intact:MINT-4137265|uniprotkb:Q543N2|uniprotkb:Q3UJR5|ensembl:ENSMUSP00000022816|ensembl:ENSMUSP00000106130 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tcp4_mouse(display_long)|uniprotkb:Sub1(gene name)|psi-mi:Sub1(display_short)|uniprotkb:Pc4(gene name synonym)|uniprotkb:Rpo2tc1(gene name synonym)|uniprotkb:SUB1 homolog(gene name synonym)|uniprotkb:Positive cofactor 4(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein p9(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035424.1|refseq:XP_006520105.1|ensembl:ENSMUSG00000022205(gene)|ensembl:ENSMUST00000022816(transcript)|ensembl:ENSMUST00000110504(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0051053"(negative regulation of DNA metabolic process)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|mint:P11031 - - comment:mint|function:"General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA)" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:zvJvb8zTLUcTvUpPAilkSlxz4Lc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BTI8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8328602|uniprotkb:E9QNB0|uniprotkb:Q3TBY5|uniprotkb:Q569P9|uniprotkb:Q80U37|intact:MINT-4112373|uniprotkb:Q8K383|ensembl:ENSMUSP00000139842 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:srrm2_mouse(display_long)|uniprotkb:Srrm2(gene name)|psi-mi:Srrm2(display_short)|uniprotkb:Kiaa0324(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_780438.2|refseq:XP_006525139.1|refseq:XP_006525140.1|ensembl:ENSMUSG00000039218(gene)|ensembl:ENSMUST00000190686(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q8BTI8|reactome:R-MMU-72163 - - function:Part of pre- and post-splicing multiprotein mRNP complexes. May be involved in pre-mRNA processing events. Binds to RNA|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PTLJsCjqGftaxq5deG19BhEASWo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q7TMY4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8340269|uniprotkb:Q80VT4|intact:MINT-4124784|uniprotkb:Q3UIA6|uniprotkb:Q9CQ50|ensembl:ENSMUSP00000065819 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:thoc7_mouse(display_long)|uniprotkb:Thoc7(gene name)|psi-mi:Thoc7(display_short)|uniprotkb:Nif3l1bp1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001272709.1|refseq:NP_079711.1|ensembl:ENSMUSG00000053453(gene)|ensembl:ENSMUST00000065865(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q7TMY4|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:3UtTcx+bM9GhFs7wEszmdWTvGFw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D287 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8338824|uniprotkb:Q91YX8|intact:MINT-4126699|uniprotkb:Q9DAI0|uniprotkb:Q3TKJ5|uniprotkb:Q9D2U4|ensembl:ENSMUSP00000005830 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:spf27_mouse(display_long)|uniprotkb:Bcas2(gene name)|psi-mi:Bcas2(display_short)|uniprotkb:Dam1(gene name synonym)|uniprotkb:Breast carcinoma-amplified sequence 2 homolog(gene name synonym)|uniprotkb:DNA amplified in mammary carcinoma 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080878.2|ensembl:ENSMUSG00000005687(gene)|ensembl:ENSMUST00000005830(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008409(Breast carcinoma amplified sequence 2)|mint:Q9D287|reactome:R-MMU-72163 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:yBhnwZOlEWsxnRIeuf/Z85O/QSQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CYL5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8402467|uniprotkb:Q3TJ42|intact:MINT-4095627|uniprotkb:Q8BTK4|ensembl:ENSMUSP00000030202 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gapr1_mouse(display_long)|uniprotkb:Glipr2(gene name)|psi-mi:Glipr2(display_short)|uniprotkb:Gapr1(gene name synonym)|uniprotkb:Glioma pathogenesis-related protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081726.1|ensembl:ENSMUSG00000028480(gene)|ensembl:ENSMUST00000030202(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001283(Allergen V5/Tpx-1 related)|interpro:IPR014044(SCP-like extracellular)|interpro:IPR018244|interpro:IPR034113|interpro:IPR035940|mint:Q9CYL5 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:liLPf1n9O6tScNMj8V1JmBL+w2s10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P61750 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7569554|uniprotkb:Q9CXX3|uniprotkb:Q3TGC2|intact:MINT-1866425|uniprotkb:P36403|ensembl:ENSMUSP00000022429 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arf4_mouse(display_long)|uniprotkb:Arf4(gene name)|psi-mi:Arf4(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_031505.1|ensembl:ENSMUSG00000021877(gene)|ensembl:ENSMUST00000022429(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61750|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434 - - function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:UQ8GuyD6go1ZCYpUU69uTevxoVo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R480 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8585721|ensembl:ENSMUSP00000021085|uniprotkb:A2A9X0|intact:UNK-5525272|uniprotkb:Q9CYI9|uniprotkb:A2A9W9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nup85_mouse(display_long)|uniprotkb:Nup85(gene name)|psi-mi:Nup85(display_short)|uniprotkb:Pcnt1(gene name synonym)|uniprotkb:Nucleoporin Nup85(gene name synonym)|uniprotkb:85 kDa nucleoporin(gene name synonym)|uniprotkb:Pericentrin-1(gene name synonym)|uniprotkb:FROUNT(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0072006"(nephron development)|interpro:IPR011502(Nucleoporin, Nup85-like)|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025|go:"GO:0048246"(macrophage chemotaxis)|ensembl:ENSMUST00000021085(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031727"(CCR2 chemokine receptor binding)|go:"GO:0031965"(nuclear membrane)|ensembl:ENSMUSG00000020739(gene)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001002929.3 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PXgdzGEcm1iHtDHZoV/eUsXkitE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0F4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8429930|intact:MINT-4126413|uniprotkb:Q8BTK6|uniprotkb:Q8R324|uniprotkb:Q8BYT5|uniprotkb:Q9CSH4|ensembl:ENSMUSP00000016553 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nkap_mouse(display_long)|uniprotkb:Nkap(gene name)|psi-mi:Nkap(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080213.3|ensembl:ENSMUSG00000016409(gene)|ensembl:ENSMUST00000016553(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466|mint:Q9D0F4 - - comment:mint|function:Regulator of TNF and IL-1 induced NF-kappa-B activation figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:2QBUDGUPz3oY0e5Og0Cx3Pnp7e810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8K354 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8321969|intact:MINT-4117620|ensembl:ENSMUSP00000047712 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cbr3_mouse(display_long)|uniprotkb:Cbr3(gene name)|psi-mi:Cbr3(display_short)|uniprotkb:NADPH-dependent carbonyl reductase 3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_766635.1|ensembl:ENSMUSG00000022947(gene)|ensembl:ENSMUST00000039620(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042376"(phylloquinone catabolic process)|go:"GO:0050890"(cognition)|go:"GO:0070402"(NADPH binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8K354|reactome:R-MMU-211945 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7MDBEB8lGtUcG+neZ3a6Ed59foM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P47856 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8311259|ensembl:ENSMUSP00000032057|uniprotkb:Q99LP7|uniprotkb:Q91XG9|intact:MINT-4096028|uniprotkb:Q99MJ4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gfpt1_mouse(display_long)|uniprotkb:Gfpt1(gene name)|psi-mi:Gfpt1(display_short)|uniprotkb:Gfpt(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 1"(gene name synonym)|uniprotkb:D-fructose-6-phosphate amidotransferase 1(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000029992(gene)|ensembl:ENSMUST00000032057(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006042"(glucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|mint:P47856|reactome:R-MMU-446210|refseq:NP_038556.1 - - comment:mint|function:Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Jumpc58JCSjLywdXrU3hcb78IXs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P25976 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7364139|intact:MINT-4084181 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ubf1_mouse(display_long)|uniprotkb:Ubtf(gene name)|psi-mi:Ubtf(display_short)|uniprotkb:Tcfubf(gene name synonym)|uniprotkb:Ubf1(gene name synonym)|uniprotkb:Ubf-1(gene name synonym)|uniprotkb:Upstream-binding factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 mint:P25976|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001165"(RNA polymerase I cis-regulatory region sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR029215|interpro:IPR036910|rcsb pdb:1V63|rcsb pdb:1V64|rcsb pdb:1WGF|reactome:R-MMU-73728|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|dip:DIP-29977N - - comment:mint|function:UBF recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:TJRBUUHHZDYhIRdbtsijzuOSbAo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CFQ3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8357842|uniprotkb:Q3ULE8|uniprotkb:Q80TX8|intact:MINT-4115593|uniprotkb:Q3U9N1|uniprotkb:P97871|ensembl:ENSMUSP00000047157 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:aqr_mouse(display_long)|uniprotkb:Aqr(gene name)|psi-mi:Aqr(display_short)|uniprotkb:Kiaa0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001277717.1|refseq:NP_033832.2|ensembl:ENSMUSG00000040383(gene)|ensembl:ENSMUST00000043160(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:Q8CFQ3|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-72163 - - function:"Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing"|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vK4CpT9ylmKvnlt3qIHEAye3mss10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CXS4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8340199|intact:MINT-4125766|uniprotkb:B2RWK8|uniprotkb:B9EK22|uniprotkb:Q5SX21|intact:MINT-8174236|uniprotkb:Q6PIA5|ensembl:ENSMUSP00000018653 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cenpv_mouse(display_long)|uniprotkb:Cenpv(gene name)|psi-mi:Cenpv(display_short)|uniprotkb:Prr6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_082724.1|ensembl:ENSMUSG00000018509(gene)|ensembl:ENSMUST00000018653(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q9CXS4 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7JgDE/uuCpLcOUBwevDaG4ljXow10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CR80 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8586255|ensembl:ENSMUSP00000003123|intact:UNK-5540354|uniprotkb:Q8K5E4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:fa32a_mouse(display_long)|uniprotkb:Otag12(gene name synonym)|uniprotkb:Ovarian tumor associated gene 12(gene name synonym)|uniprotkb:MNCb-3154(orf name)|uniprotkb:Fam32a(gene name)|psi-mi:Fam32a(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000003039(gene)|ensembl:ENSMUST00000003123(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|interpro:IPR013865(Protein of unknown function DUF1754, eukaryotic)|refseq:NP_080731.1 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:NB/GdFsA+ZC6MYUA30DZFabkEmc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80X41 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8412271|uniprotkb:Q8C2P7|intact:MINT-4140113|uniprotkb:Q91YH9|uniprotkb:O88636|uniprotkb:O88635|ensembl:ENSMUSP00000021539|ensembl:ENSMUSP00000152109 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:vrk1_mouse(display_long)|uniprotkb:Vrk1(gene name)|psi-mi:Vrk1(display_short)|uniprotkb:Serine/threonine-protein kinase 51PK(gene name synonym)|uniprotkb:Vaccinia-related kinase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001025015.1|refseq:NP_035835.1|refseq:NP_001025014.1|refseq:XP_006515872.1|refseq:XP_006515873.1|refseq:XP_006515874.1|refseq:XP_006515875.1|refseq:XP_017170535.1|ensembl:ENSMUSG00000021115(gene)|ensembl:ENSMUST00000021539(transcript)|ensembl:ENSMUST00000220629(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005795"(Golgi stack)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0035175"("histone kinase activity (H3-S10 specific)")|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0072354"("histone kinase activity (H3-T3 specific)")|go:"GO:0072355"(histone H3-T3 phosphorylation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q80X41|reactome:R-MMU-2995383 - - comment:mint|function:Serine/threonine kinase that phosphorylates 'Thr-21' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2 figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:3xwFZnWRk1XE2jX5Fot44RMOkE810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CJF7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8372944|uniprotkb:Q8VD55|uniprotkb:B2RRC8|intact:MINT-4119775|uniprotkb:Q8BVJ5|ensembl:ENSMUSP00000027768 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:elys_mouse(display_long)|uniprotkb:Ahctf1(gene name)|psi-mi:Ahctf1(display_short)|uniprotkb:Elys(gene name synonym)|uniprotkb:Embryonic large molecule derived from yolk sac(gene name synonym)|uniprotkb:Protein MEL-28(gene name synonym)|uniprotkb:Putative AT-hook-containing transcription factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080651.2|ensembl:ENSMUSG00000026491(gene)|ensembl:ENSMUST00000027768(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|interpro:IPR025151|interpro:IPR032040|mint:Q8CJF7|rcsb pdb:4I0O|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025 - - comment:mint|function:"Probable transcription factor which may play a specific role in hematopoietic tissues (PubMed:11952839). May play a role in early development being critical for the survival of inner cells of the blastocyst (PubMed:15507119)" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oGUpayyJubdbFB6Ze+TCMAz8Fco10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P48774 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8319171|uniprotkb:Q545W5|intact:MINT-4096984|ensembl:ENSMUSP00000004134 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gstm5_mouse(display_long)|uniprotkb:Gstm5(gene name)|psi-mi:Gstm5(display_short)|uniprotkb:Fsc2(gene name synonym)|uniprotkb:Gstm3(gene name synonym)|uniprotkb:GST class-mu 5(gene name synonym)|uniprotkb:Fibrous sheath component 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034490.1|ensembl:ENSMUSG00000004032(gene)|ensembl:ENSMUST00000004134(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P48774|reactome:R-MMU-156590 - - function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:MoY+H/HLLFjbYkGodfN9ORRunqo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z0P5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8319051|uniprotkb:Q3TZG2|intact:MINT-4131249|uniprotkb:Q8BN77|uniprotkb:Q9DCK8|uniprotkb:Q3TD06|ensembl:ENSMUSP00000024047 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:twf2_mouse(display_long)|uniprotkb:Twf2(gene name)|psi-mi:Twf2(display_short)|uniprotkb:Ptk9l(gene name synonym)|uniprotkb:Twinfilin-1-like protein(gene name synonym)|uniprotkb:A6-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_036006.1|dip:DIP-61549N|ensembl:ENSMUSG00000023277(gene)|ensembl:ENSMUST00000024047(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030016"(myofibril)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032420"(stereocilium)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q9Z0P5|rcsb pdb:7DS3 - - function:Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RWaTqcv6iuuBNh78sOifPKdnvKc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99JF8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8317838|uniprotkb:A2BI11|uniprotkb:Q3TTD7|uniprotkb:Q9CT03|uniprotkb:Q80WQ7|uniprotkb:Q3TEJ7|intact:MINT-4123368|uniprotkb:Q99JF7|uniprotkb:Q3UTA1|uniprotkb:Q99LR4|uniprotkb:A2BI10|ensembl:ENSMUSP00000030207 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psip1_mouse(display_long)|uniprotkb:Psip1(gene name)|psi-mi:Psip1(display_short)|uniprotkb:Ledgf(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598709.1|refseq:NP_001277456.1|ensembl:ENSMUSG00000028484(gene)|ensembl:ENSMUST00000030207(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0034399"(nuclear periphery)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:Q99JF8 - - comment:mint|function:Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Zta4EkVlkXij7w85S8romBaldU010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P43275 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8338024|uniprotkb:Q5SZ98|intact:MINT-1868385|ensembl:ENSMUSP00000062030 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h11_mouse(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1 VAR.3(gene name synonym)|uniprotkb:H1a(gene name synonym)|uniprotkb:H1f1(gene name synonym)|uniprotkb:Hist1h1a(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_085112.1|ensembl:ENSMUSG00000049539(gene)|ensembl:ENSMUST00000055770(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0031982"(vesicle)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43275|reactome:R-MMU-140342|reactome:R-MMU-2559584 - - function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:rVet/mPRsJO0PzM0pRx+ukzOLVw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q921J4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8586488|ensembl:ENSMUSP00000078459|uniprotkb:Q8CF67|intact:MINT-8178472|uniprotkb:Q3U4V7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ube2s_mouse(display_long)|uniprotkb:Ubiquitin-conjugating enzyme E2-EPF5(gene name synonym)|uniprotkb:Ubiquitin-protein ligase S(gene name synonym)|uniprotkb:Ube2s(gene name)|psi-mi:Ube2s(display_short)|uniprotkb:E2epf(gene name synonym)|uniprotkb:Ubiquitin carrier protein S(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme S(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000060860(gene)|ensembl:ENSMUST00000079496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-MMU-174048|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-176407|reactome:R-MMU-176408|reactome:R-MMU-176409|reactome:R-MMU-176412|reactome:R-MMU-179409|reactome:R-MMU-2467813|reactome:R-MMU-2559582|reactome:R-MMU-69017|reactome:R-MMU-8866652|reactome:R-MMU-983168|reactome:R-MMU-141430|refseq:NP_598538.1 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:XRSpnVB95iXtAE45TtyW2ukxMWw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q00PI9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8586171|ensembl:ENSMUSP00000094515|uniprotkb:F8VPM4|intact:UNK-5385063 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hnrl2_mouse(display_long)|uniprotkb:Manp(gene name synonym)|uniprotkb:Hnrpul2(gene name synonym)|uniprotkb:MLF1-associated nuclear protein(gene name synonym)|uniprotkb:Hnrnpul2(gene name)|psi-mi:Hnrnpul2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000071659(gene)|ensembl:ENSMUST00000096753(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|refseq:NP_001074665.1 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oPTke2/M1XC8ou8Lcc4UY4Qz8sw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q7TNV0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8340579|uniprotkb:Q8BZV6|uniprotkb:Q80VC5|intact:MINT-1868135|ensembl:ENSMUSP00000021807 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dek_mouse(display_long)|uniprotkb:Dek(gene name)|psi-mi:Dek(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080176.2|ensembl:ENSMUSG00000021377(gene)|ensembl:ENSMUST00000021807(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:Q7TNV0|reactome:R-MMU-5250924|reactome:R-MMU-8864260 - - comment:mint|function:May have a function in the nucleus figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vzAw0iLJp4Iq3k447Ks/10bngUg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O54962 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8339835|intact:MINT-4089048|uniprotkb:Q542E6|ensembl:ENSMUSP00000025762|ensembl:ENSMUSP00000126202|ensembl:ENSMUSP00000158117 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:baf_mouse(display_long)|uniprotkb:Banf1(gene name)|psi-mi:Banf1(display_short)|uniprotkb:Baf(gene name synonym)|uniprotkb:Bcrp1(gene name synonym)|uniprotkb:L2bp1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym)|uniprotkb:LAP2-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001273537.1|refseq:NP_001033320.1|refseq:NP_035923.1|ensembl:ENSMUSG00000024844(gene)|ensembl:ENSMUST00000025762(transcript)|ensembl:ENSMUST00000170010(transcript)|ensembl:ENSMUST00000237167(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015074"(DNA integration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O54962 - - comment:mint|function:Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:riA14y6mw1H3uPuYlNaVDKq+gsc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TIX9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8328548|uniprotkb:Q8BLI5|uniprotkb:Q9CQR1|uniprotkb:Q8BZZ5|intact:MINT-4113699|uniprotkb:Q3TI55|ensembl:ENSMUSP00000064515 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:snut2_mouse(display_long)|uniprotkb:Usp39(gene name)|psi-mi:Usp39(display_short)|uniprotkb:Inactive ubiquitin-specific peptidase 39(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_613058.1|ensembl:ENSMUSG00000056305(gene)|ensembl:ENSMUST00000070345(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051301"(cell division)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR028889|interpro:IPR033809|interpro:IPR038765|mint:Q3TIX9|reactome:R-MMU-72163 - - comment:mint|function:"May play a role in mRNA splicing. It is unsure if the protein really exhibits hydrolase activity. Could be a competitor of ubiquitin C-terminal hydrolases (UCHs)" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Wslfw2+ESrvoQNHZYIduTFA1Q3Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62307 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8341112|intact:MINT-1527856|uniprotkb:Q15356|ensembl:ENSMUSP00000020203 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ruxf_mouse(display_long)|uniprotkb:Snrpf(gene name)|psi-mi:Snrpf(display_short)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081522.1|ensembl:ENSMUSG00000020018(gene)|ensembl:ENSMUST00000020203(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62307|reactome:R-MMU-111367|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-73856|reactome:R-MMU-77588 - - function:Associated with snRNP U1, U2, U4/U6 and U5|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q0VBL3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8572651|intact:EBI-11518552|intact:EBI-9989873|intact:EBI-16360075|uniprotkb:A0PJG5|uniprotkb:Q3THK4|uniprotkb:Q3TLX0|uniprotkb:Q571M7|uniprotkb:Q66JP8|uniprotkb:Q6PGG1|uniprotkb:Q7TT82|ensembl:ENSMUSP00000054424|intact:MINT-8174194 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rbm15_mouse(display_long)|uniprotkb:Kiaa4257(gene name synonym)|uniprotkb:One-twenty two protein 1(gene name synonym)|uniprotkb:Ott1(gene name synonym)|uniprotkb:RNA-binding motif protein 15(gene name synonym)|uniprotkb:Rbm15(gene name)|psi-mi:Rbm15(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001039272.1|ensembl:ENSMUSG00000048109(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|ensembl:ENSMUST00000061772(transcript)|go:"GO:0048536"(spleen development)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034470|interpro:IPR034472|interpro:IPR034473|interpro:IPR035979 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:09qhcrNbUkJFdyi2RiYw3SDXVW410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JM93 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8329873|intact:MINT-4130392|uniprotkb:Q9WUG8|ensembl:ENSMUSP00000031351 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ar6p4_mouse(display_long)|uniprotkb:Splicing factor SRrp37(gene name synonym)|uniprotkb:Arl6ip4(gene name)|psi-mi:Arl6ip4(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_653092.1|ensembl:ENSMUSG00000029404(gene)|ensembl:ENSMUST00000031351(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|interpro:IPR019532|mint:Q9JM93 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:EzflOSehdFGvg1Bc4l3SctKoV9U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQ22 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8328730|uniprotkb:Q9CYS0|intact:MINT-1870311|intact:MINT-4124770|ensembl:ENSMUSP00000033131 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ltor1_mouse(display_long)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1(gene name synonym)|uniprotkb:Lipid raft adaptor protein p18(gene name synonym)|uniprotkb:Lamtor1(gene name)|psi-mi:Lamtor1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079881.2|ensembl:ENSMUSG00000030842(gene)|ensembl:ENSMUST00000033131(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010872"(regulation of cholesterol esterification)|go:"GO:0010874"(regulation of cholesterol efflux)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060620"(regulation of cholesterol import)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|interpro:IPR028209|mint:Q9CQ22|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9639288 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:DDzxcCbfpNbaFdldFxAR1QuFpXE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CWJ9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8319266|uniprotkb:Q9CZW9|uniprotkb:Q8BPF0|uniprotkb:Q9CRI1|uniprotkb:Q8BQV9|intact:MINT-1855853|uniprotkb:Q80UH0|uniprotkb:Q3UTQ3|ensembl:ENSMUSP00000027384 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pur9_mouse(display_long)|uniprotkb:Atic(gene name)|psi-mi:Atic(display_short)|uniprotkb:Purh(gene name synonym)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080471.2|ensembl:ENSMUSG00000026192(gene)|ensembl:ENSMUST00000027384(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009259"(ribonucleotide metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|mint:Q9CWJ9|reactome:R-MMU-73817 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qLk0xmb2bc+Jcxmw7Z4sF0SKJV010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BHL4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8402180|intact:MINT-4131759|uniprotkb:Q8K1G5|uniprotkb:Q8K067 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rai3_mouse(display_long)|uniprotkb:Gprc5a(gene name)|psi-mi:Gprc5a(display_short)|uniprotkb:Rai3(gene name synonym)|uniprotkb:Raig1(gene name synonym)|uniprotkb:G-protein coupled receptor family C group 5 member A(gene name synonym)|uniprotkb:Retinoic acid-induced gene 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR017978|mint:Q8BHL4|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031982"(vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome) - - comment:mint|function:Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/zfVtq+p8c2a7A0Dw61HijaOhO410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JMD0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8372737|intact:MINT-4131445|uniprotkb:E9PW12|uniprotkb:Q99LA2|uniprotkb:Q9Z326|ensembl:ENSMUSP00000054168 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:zn207_mouse(display_long)|uniprotkb:Znf207(gene name)|psi-mi:Znf207(display_short)|uniprotkb:49 kDa zinc finger protein(gene name synonym)|uniprotkb:Bugz(gene name synonym)|uniprotkb:Zep(gene name synonym)|uniprotkb:Zfp207(gene name synonym)|uniprotkb:Zinc finger protein 207(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001123641.1|refseq:NP_001123643.1|refseq:XP_006533252.1|refseq:NP_001123642.1|refseq:NP_035881.1|ensembl:ENSMUSG00000017421(gene)|ensembl:ENSMUST00000053740(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990047"(spindle matrix)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q9JMD0 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+d+eZB64qhBDmY6NK3ujA5KWYBs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P58871 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8400054|uniprotkb:A2BH84|intact:MINT-4137005|uniprotkb:Q6ZPI8|ensembl:ENSMUSP00000107232 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tb182_mouse(display_long)|uniprotkb:Tnks1bp1(gene name)|psi-mi:Tnks1bp1(display_short)|uniprotkb:Tab182(gene name synonym)|uniprotkb:Kiaa1741(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001074729.1|refseq:XP_017173105.1|ensembl:ENSMUSG00000033955(gene)|ensembl:ENSMUST00000111605(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|mint:P58871|reactome:R-MMU-429947|reactome:R-MMU-6804115 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:fRfsW/fpdOeuX/17jeteOhNX0Xs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70698 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8315043|ensembl:ENSMUSP00000030381|intact:MINT-4109278|uniprotkb:Q922Y4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pyrg1_mouse(display_long)|uniprotkb:Ctps1(gene name)|psi-mi:Ctps1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)|uniprotkb:Ctps(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000028633(gene)|ensembl:ENSMUST00000030381(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P70698|reactome:R-MMU-499943|go:"GO:0097268"(cytoophidium)|refseq:NP_058028.2|refseq:XP_006503288.1 - - comment:mint|function:Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:quZcdHIjclMThgMd5MT+Vlsed9810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922V4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8339071|uniprotkb:O55039|intact:MINT-4107987|ensembl:ENSMUSP00000114968 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:plrg1_mouse(display_long)|uniprotkb:Plrg1(gene name)|psi-mi:Plrg1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_058064.2|ensembl:ENSMUSG00000027998(gene)|ensembl:ENSMUST00000150268(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q922V4|reactome:R-MMU-72163 - - function:Necessary for spliceosome assembly and for pre-mRNA splicing|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:h7ILw7JCfPhjX2tdlQhnVjhpq9U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CRB2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8340718|intact:MINT-4125123|ensembl:ENSMUSP00000120014 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nhp2_mouse(display_long)|uniprotkb:Nhp2(gene name)|psi-mi:Nhp2(display_short)|uniprotkb:Nola2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:Nucleolar protein family A member 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080907.1|ensembl:ENSMUSG00000001056(gene)|ensembl:ENSMUST00000127405(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9CRB2|reactome:R-MMU-171319 - - function:"Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\"psi\") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme"|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8GeIJuNENgcWIOXcOlRz+wdVujQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80TH2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7320461|uniprotkb:Q8K171|uniprotkb:E9QND6|uniprotkb:Q8CE41|uniprotkb:Q8BQ14|uniprotkb:Q9JI47|intact:MINT-138078|uniprotkb:Q99JU3|ensembl:ENSMUSP00000088813 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:erbin_mouse(display_long)|uniprotkb:Erbin(gene name)|psi-mi:Erbin(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:Erbb2ip(gene name synonym)|uniprotkb:Kiaa1225(gene name synonym)|uniprotkb:Lap2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000021709(gene)|ensembl:ENSMUST00000091269(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099572"(postsynaptic specialization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|reactome:R-MMU-1227986|reactome:R-MMU-8863795|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9652282|refseq:NP_001005868.1|refseq:NP_001276402.1|refseq:NP_001276403.1|refseq:NP_001276404.1 - - comment:mint|function:Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ERBB2 'Tyr-1248' receptor, it may contribute to stabilize this unphosphorylated state figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8/YYmKxiql+Xa8+qsF+qTgYSU0M10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BHG9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8412643|uniprotkb:Q8K2K1|intact:MINT-4110542|ensembl:ENSMUSP00000065845 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cgbp1_mouse(display_long)|uniprotkb:Cggbp1(gene name)|psi-mi:Cggbp1(display_short)|uniprotkb:20 kDa CGG-binding protein(gene name synonym)|uniprotkb:p20-CGGBP DNA-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_848762.1|refseq:XP_006521721.1|ensembl:ENSMUSG00000054604(gene)|ensembl:ENSMUST00000067744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042802"(identical protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR033375|mint:Q8BHG9 - - comment:mint|function:"Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:TmV9hNe8qdVZl0lGf+qjS/YPriI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8K297 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8585628|ensembl:ENSMUSP00000047923|uniprotkb:Q6PGL1|uniprotkb:Q3V3R5|intact:MINT-1866727 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gt251_mouse(display_long)|uniprotkb:Colgalt1(gene name)|psi-mi:Colgalt1(display_short)|uniprotkb:"Collagen beta(1-O)galactosyltransferase 1"(gene name synonym)|uniprotkb:Glt25d1(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 1(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000034807(gene)|ensembl:ENSMUST00000047903(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:1904028"(positive regulation of collagen fibril organization)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|reactome:R-MMU-1650814|refseq:NP_666323.2 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:sO593anpq/qj2iMKT/jucDbdWtE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P28352 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8418506|intact:MINT-4088018|ensembl:ENSMUSP00000042602 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:apex1_mouse(display_long)|uniprotkb:Apex1(gene name)|psi-mi:Apex1(display_short)|uniprotkb:Ape(gene name synonym)|uniprotkb:Apex(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)|uniprotkb:Ref1(gene name synonym)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033817.1|ensembl:ENSMUSG00000035960(gene)|ensembl:ENSMUST00000049411(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P28352|rcsb pdb:7CD5|rcsb pdb:7CD6|reactome:R-MMU-110357|reactome:R-MMU-110362|reactome:R-MMU-110373|reactome:R-MMU-5651801|reactome:R-MMU-73930|reactome:R-MMU-73933 - - comment:mint|function:Repairs oxidative DNA damages in vitro. May have a role in protection against cell lethality and suppression of mutations. Removes the blocking groups from the 3'-termini of the DNA strand breaks generated by ionizing radiations and bleomycin figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:fMTsVKLA4YjVrgOK0FCa3jpenbU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R3N6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8339876|uniprotkb:Q8BXY3|uniprotkb:Q8BWD5|intact:MINT-4137684|ensembl:ENSMUSP00000025137 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:thoc1_mouse(display_long)|uniprotkb:Thoc1(gene name)|psi-mi:Thoc1(display_short)|uniprotkb:Hpr1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_705780.1|ensembl:ENSMUSG00000024287(gene)|ensembl:ENSMUST00000025137(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q8R3N6|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - function:The THO/TREX complex is recruited to transcribed genes and travels with the RNA polymerase during elongation. It may physically link proteins that function in transcription and in RNA export|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Uz/HUphb7mFTNFZnJXumoC7r32010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P15379 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7565891|intact:EBI-15579519|uniprotkb:Q62063|uniprotkb:Q62061|uniprotkb:Q05732|intact:UNK-5943644|uniprotkb:Q9QYX8|uniprotkb:Q62408|uniprotkb:Q99J14|uniprotkb:Q64296|uniprotkb:Q61395|uniprotkb:Q62060|uniprotkb:Q62062|uniprotkb:Q62409 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cd44_mouse(display_long)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Cd44(gene name)|psi-mi:Cd44(display_short)|uniprotkb:Ly-24(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Lymphocyte antigen 24(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001171257.1|refseq:NP_001034240.1|refseq:NP_001171258.1|refseq:NP_033981.2|refseq:NP_001171256.1|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034238"(macrophage fusion)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070487"(monocyte aggregation)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|rcsb pdb:2JCP|rcsb pdb:2JCQ|rcsb pdb:5BZJ|rcsb pdb:2JCR|rcsb pdb:5BZK|rcsb pdb:5BZL|rcsb pdb:5BZM|rcsb pdb:5BZN|rcsb pdb:5BZO|rcsb pdb:2ZPY|rcsb pdb:5BZP|rcsb pdb:5BZQ|rcsb pdb:5BZR|rcsb pdb:5BZS|rcsb pdb:5BZT|rcsb pdb:4MRD|rcsb pdb:4MRE|rcsb pdb:4MRF|rcsb pdb:4MRG|rcsb pdb:4MRH|rcsb pdb:4NP2|rcsb pdb:4NP3|rcsb pdb:5BZC|rcsb pdb:5BZE|rcsb pdb:5BZF|rcsb pdb:5BZG|rcsb pdb:5BZH|rcsb pdb:5BZI|dip:DIP-29095N|reactome:R-MMU-1474228|reactome:R-MMU-202733|reactome:R-MMU-216083|reactome:R-MMU-2160916|reactome:R-MMU-6798695 - - function:Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1Rlb+aBsm9z0HJuB6Oz4Oilui1o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91W39 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8329509|uniprotkb:A2A5L2|intact:MINT-4103204|ensembl:ENSMUSP00000046388 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ncoa5_mouse(display_long)|uniprotkb:Ncoa5(gene name)|psi-mi:Ncoa5(display_short)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_659141.1|ensembl:ENSMUSG00000039804(gene)|ensembl:ENSMUST00000040381(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q91W39 - - comment:mint|function:"Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2)" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:wPwJKZRExN0LsGR8FyKm74oUm2g10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91Z49 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8339660|intact:MINT-4122183|uniprotkb:Q8BVM8|uniprotkb:Q3TJ68|uniprotkb:Q921B0|uniprotkb:Q3UT89|uniprotkb:Q8K361|uniprotkb:Q9D6A8|ensembl:ENSMUSP00000023489 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:uif_mouse(display_long)|uniprotkb:Fyttd1(gene name)|psi-mi:Fyttd1(display_short)|uniprotkb:Uif(gene name synonym)|uniprotkb:Forty-two-three domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081502.2|refseq:NP_001152821.1|ensembl:ENSMUSG00000022800(gene)|ensembl:ENSMUST00000023489(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|interpro:IPR009782(Protein of unknown function DUF1346)|mint:Q91Z49|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7wZ/+DcJnQinUp/719WfCsCg5V410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P45591 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8313728|ensembl:ENSMUSP00000077262|intact:MINT-1869247 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cof2_mouse(display_long)|uniprotkb:Cfl2(gene name)|psi-mi:Cfl2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000062929(gene)|ensembl:ENSMUST00000078124(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P45591|refseq:NP_031714.1 - - comment:mint|function:"Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:IGCzZg3kPYp44b0TRKSQJxsE5QA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q04736 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7141897|ensembl:ENSMUSP00000072154|ensembl:ENSMUSP00000132161|ensembl:ENSMUSP00000144001|intact:UNK-6057702 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:yes_mouse(display_long)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:Yes1(gene name)|psi-mi:Yes1(display_short)|uniprotkb:Yes(gene name synonym)|uniprotkb:p61-Yes(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000014932(gene)|ensembl:ENSMUST00000072311(transcript)|ensembl:ENSMUST00000168707(transcript)|ensembl:ENSMUST00000202543(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2YT6|rcsb pdb:5MTJ|reactome:R-MMU-1227986|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928665|reactome:R-MMU-912631|refseq:NP_001192062.1|refseq:NP_001192061.1|refseq:NP_033561.1 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:84OLtJ0uJKdhydIFeFjgC6Q96Jg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9ET30 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8365486|intact:MINT-1851936|ensembl:ENSMUSP00000158318 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tm9s3_mouse(display_long)|uniprotkb:Tm9sf3(gene name)|psi-mi:Tm9sf3(display_short)|uniprotkb:Smbp(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_579930.1|ensembl:ENSMUSG00000025016(gene)|ensembl:ENSMUST00000237871(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q9ET30 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6NBtZ5n+EIS45rnn6JOCgN9t05410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D868 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8338657|intact:MINT-4108453|uniprotkb:Q9CQU7|ensembl:ENSMUSP00000101924 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ppih_mouse(display_long)|uniprotkb:Ppih(gene name)|psi-mi:Ppih(display_short)|uniprotkb:Rotamase H(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001103599.1|refseq:NP_082953.1|refseq:NP_001103600.1|ensembl:ENSMUSG00000060288(gene)|ensembl:ENSMUST00000106317(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:Q9D868|reactome:R-MMU-72163 - - function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. May act as a chaperone|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oCpawZTnkvUVSHt6hJcN/Y023u410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BMC4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8357531|intact:MINT-4091142|uniprotkb:Q8VEF9|uniprotkb:Q9D5A8|uniprotkb:Q9D0C6|uniprotkb:Q3TW87|uniprotkb:Q8BKR9|uniprotkb:Q8BYV4|ensembl:ENSMUSP00000019441 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nop9_mouse(display_long)|uniprotkb:Nop9(gene name)|psi-mi:Nop9(display_short)|uniprotkb:Pumilio domain-containing protein NOP9(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080679.3|ensembl:ENSMUSG00000019297(gene)|ensembl:ENSMUST00000019441(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040000|mint:Q8BMC4 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:MXv1JCLCUq31FQ3LR2IX+sQhKFE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JKX6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8393097|uniprotkb:A2ATT6|intact:MINT-4104265|uniprotkb:Q99KM4|ensembl:ENSMUSP00000026927|ensembl:ENSMUSP00000136233 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nudt5_mouse(display_long)|uniprotkb:Nudt5(gene name)|psi-mi:Nudt5(display_short)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 5(gene name synonym)|uniprotkb:8-oxo-dGDP phosphatase(gene name synonym)|uniprotkb:Nuclear ATP-synthesis protein NUDIX5(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_058614.1|refseq:XP_006497575.1|refseq:XP_006497576.1|ensembl:ENSMUSG00000025817(gene)|ensembl:ENSMUST00000026927(transcript)|ensembl:ENSMUST00000179748(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0009191"(ribonucleoside diphosphate catabolic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017110"(nucleoside-diphosphatase activity)|go:"GO:0019144"(ADP-sugar diphosphatase activity)|go:"GO:0019303"(D-ribose catabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0030515"(snoRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|mint:Q9JKX6|reactome:R-MMU-2393930 - - comment:mint|function:"Hydrolyzes with similar activities ADP-ribose and ADP-mannose. Can also hydrolyzes ADP-glucose (40% of ADP-ribose activity) and other nucleotide sugars with low activity (10%)" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+mAPO0HDoIz8fI4mcFqmfx+zq5E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CH02 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8340680|uniprotkb:Q0VAT9|uniprotkb:Q8R094|intact:MINT-4115847|uniprotkb:Q3U0W3|ensembl:ENSMUSP00000011450 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sugp1_mouse(display_long)|uniprotkb:Sugp1(gene name)|psi-mi:Sugp1(display_short)|uniprotkb:Sf4(gene name synonym)|uniprotkb:Splicing factor 4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081757.1|refseq:XP_006509801.1|ensembl:ENSMUSG00000011306(gene)|ensembl:ENSMUST00000011450(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8CH02|rcsb pdb:1UG0|rcsb pdb:1X4O|reactome:R-MMU-72163 - - comment:mint|function:Plays a role in premRNA splicing figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Oiwyc1+r7jMfs+D7PFkJyqh+c+U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P23949 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8392537|intact:MINT-4137984|uniprotkb:B9EIF6|uniprotkb:Q3TCE3|uniprotkb:Q3TU59|ensembl:ENSMUSP00000050820 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tisd_mouse(display_long)|uniprotkb:Zfp36l2(gene name)|psi-mi:Zfp36l2(display_short)|uniprotkb:Tis11d(gene name synonym)|uniprotkb:Butyrate response factor 2(gene name synonym)|uniprotkb:TPA-induced sequence 11d(gene name synonym)|uniprotkb:Zinc finger protein 36, C3H1 type-like 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001001806.1|ensembl:ENSMUSG00000045817(gene)|ensembl:ENSMUST00000060366(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901991"(negative regulation of mitotic cell cycle phase transition)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR007635(Tis11B like protein, N-terminal)|interpro:IPR036855|mint:P23949 - - function:"Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation"|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:iPHaXGG46do54N3HBj7ZIqbmCes10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P46737 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8360920|uniprotkb:A8Y5K0|intact:MINT-4089567|uniprotkb:Q9D025|uniprotkb:Q3UDZ4|uniprotkb:A3KGA9|ensembl:ENSMUSP00000033544|ensembl:ENSMUSP00000109708 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:brcc3_mouse(display_long)|uniprotkb:Brcc3(gene name)|psi-mi:Brcc3(display_short)|uniprotkb:C6.1a(gene name synonym)|uniprotkb:BRCA1-A complex subunit BRCC36(gene name synonym)|uniprotkb:BRISC complex subunit BRCC36(gene name synonym)|uniprotkb:BRCA1/BRCA2-containing complex subunit 3(gene name synonym)|uniprotkb:BRCA1/BRCA2-containing complex subunit 36(gene name synonym)|uniprotkb:Brcc36(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_011245856.1|refseq:NP_001159929.1|refseq:NP_001159931.1|refseq:NP_666068.1|ensembl:ENSMUSG00000031201(gene)|ensembl:ENSMUST00000033544(transcript)|ensembl:ENSMUST00000114074(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000152"(nuclear ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070537"(histone H2A K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR033860|interpro:IPR037518|interpro:IPR040749|mint:P46737|rcsb pdb:6GVW|reactome:R-MMU-5689901|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-69473 - - comment:mint|function:Plays a role in modulation of E3 ubiquitin ligase activity of the 2 subunit BRCA1/BARD1 complex figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jo9PdNjnwLnEBw0LPWwjFYf6ve010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D2R0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8361869|uniprotkb:A1IG47|intact:MINT-4126762|uniprotkb:Q3TCL8|uniprotkb:Q3UD39|ensembl:ENSMUSP00000031445 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:aacs_mouse(display_long)|uniprotkb:Aacs(gene name)|psi-mi:Aacs(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_084486.1|ensembl:ENSMUSG00000029482(gene)|ensembl:ENSMUST00000031445(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0030729"(acetoacetate-CoA ligase activity)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034201"(response to oleic acid)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0045471"(response to ethanol)|go:"GO:0047760"(butyrate-CoA ligase activity)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071397"(cellular response to cholesterol)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR005914(Acetoacetyl-CoA synthase)|interpro:IPR020845|interpro:IPR032387|interpro:IPR042099|mint:Q9D2R0|reactome:R-MMU-77111 - - comment:mint|function:Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:45JMzn/liUGmqhYrZZ/s9sl0IRs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P97363 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8400764|uniprotkb:P97356|intact:MINT-4100293|ensembl:ENSMUSP00000021424 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sptc2_mouse(display_long)|uniprotkb:Sptlc2(gene name)|psi-mi:Sptlc2(display_short)|uniprotkb:Lcb2(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035609.1|ensembl:ENSMUSG00000021036(gene)|ensembl:ENSMUST00000021424(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P97363|reactome:R-MMU-1660661 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ZEGrDiFI9eAPF7tbXQ96GA7BkgI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q05909 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8401242|intact:MINT-4109151 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ptprg_mouse(display_long)|uniprotkb:Ptprg(gene name)|psi-mi:Ptprg(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_033007.2|interpro:IPR029021|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR036116|interpro:IPR036398|mint:Q05909|interpro:IPR041887|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:1901998"(toxin transport)|rcsb pdb:3JXG|rcsb pdb:3KLD|rcsb pdb:5E5U|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003961(Fibronectin, type III) - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:A3yle/ZJ+6KwMUpStmKbedmO4LI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D3D9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8329654|intact:MINT-4126883|ensembl:ENSMUSP00000003156|ensembl:ENSMUSP00000101006 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:atpd_mouse(display_long)|uniprotkb:Atp5f1d(gene name)|psi-mi:Atp5f1d(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:Atp5d(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079589.2|refseq:XP_017169541.1|ensembl:ENSMUSG00000003072(gene)|ensembl:ENSMUST00000003156(transcript)|ensembl:ENSMUST00000105367(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:Q9D3D9|reactome:R-MMU-163210|reactome:R-MMU-8949613 - - function:"Mitochondrial membrane ATP synthase (F(1)F(O) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits"|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:OnHrRT8QSvjfiVkcCbJDVWPLD8I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QUR6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8344942|intact:MINT-1854903|uniprotkb:Q80YS1|ensembl:ENSMUSP00000097444 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ppce_mouse(display_long)|uniprotkb:Prep(gene name)|psi-mi:Prep(display_short)|uniprotkb:Pep(gene name synonym)|uniprotkb:Post-proline cleaving enzyme(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035286.1|ensembl:ENSMUSG00000019849(gene)|ensembl:ENSMUST00000099858(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0070012"(oligopeptidase activity)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR023302|interpro:IPR029058|mint:Q9QUR6 - - comment:mint|function:Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:LrkDBZS1o6Br0r14vkmXkGf5D4o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VEH3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8313699|ensembl:ENSMUSP00000027684|uniprotkb:Q9CTB0|intact:MINT-4120060|uniprotkb:Q99KS1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arl8a_mouse(display_long)|uniprotkb:Arl8a(gene name)|psi-mi:Arl8a(display_short)|uniprotkb:Arl10b(gene name synonym)|uniprotkb:Gie2(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 10B(gene name synonym)|uniprotkb:Novel small G protein indispensable for equal chromosome segregation 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000026426(gene)|ensembl:ENSMUST00000027684(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044154|mint:Q8VEH3|reactome:R-MMU-6798695|refseq:NP_081099.1 - - function:May play a role in lysosomes motility. Alternatively, may play a role in chromosomes segregation|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8+7GJ2m7t5/hsw0XdfgZmxYV+bs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80VD1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8312352|ensembl:ENSMUSP00000028825|intact:MINT-4125185|uniprotkb:A2ATZ4|uniprotkb:Q9CS37|uniprotkb:Q9CS28 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:fa98b_mouse(display_long)|uniprotkb:Fam98b(gene name)|psi-mi:Fam98b(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000027349(gene)|ensembl:ENSMUST00000028825(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|mint:Q80VD1|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR018797|refseq:NP_080896.2 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RhwdW3SPEJ+fy34p2EuYxovNQno10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q62203 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8327363|intact:MINT-4134285 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sf3a2_mouse(display_long)|uniprotkb:Sf3a2(gene name)|psi-mi:Sf3a2(display_short)|uniprotkb:Sap62(gene name synonym)|uniprotkb:Spliceosome-associated protein 62(gene name synonym)|uniprotkb:SF3a66(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR036236|interpro:IPR031781|mint:Q62203|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|reactome:R-MMU-72163 - - function:"Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex"|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FDGaFD4YyUzaNlPFZjyeiL8NzqQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z2Q2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8459573|uniprotkb:Q9D7H7|uniprotkb:Q7TMJ4|uniprotkb:Q3TKK6|uniprotkb:Q8BJI0|intact:MINT-4131404 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:knop1_mouse(display_long)|uniprotkb:Knop1(gene name)|psi-mi:Knop1(display_short)|uniprotkb:Testis-specific gene 118 protein(gene name synonym)|uniprotkb:Tsg118(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001161691.1|refseq:NP_075686.2|refseq:NP_001161692.1|refseq:NP_001161690.1|interpro:IPR028124|mint:Q9Z2Q2|go:"GO:0005730"(nucleolus) - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jYZowTCOxQeDsmhT0/3Unik2glc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91VS8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8586315|ensembl:ENSMUSP00000112725|uniprotkb:E9QJS4|uniprotkb:Q3TAP2|uniprotkb:Q69ZZ0|intact:MINT-8178498 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:farp2_mouse(display_long)|uniprotkb:Farp2(gene name)|psi-mi:Farp2(display_short)|uniprotkb:FERM domain including RhoGEF(gene name synonym)|uniprotkb:Kiaa0793(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000034066(gene)|ensembl:ENSMUST00000120301(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0022405"(hair cycle process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0033623"(regulation of integrin activation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071800"(podosome assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|rcsb pdb:4GYV|rcsb pdb:4GZU|rcsb pdb:6D2K|reactome:R-MMU-399955|reactome:R-MMU-9013149|refseq:NP_663494.2 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:KUKm5dHMjLQFpiBVcm9T1rekSw010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O88696 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8354072|intact:MINT-1850742|uniprotkb:Q3TI13|ensembl:ENSMUSP00000002735 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:clpp_mouse(display_long)|uniprotkb:Clpp(gene name)|psi-mi:Clpp(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_059089.1|ensembl:ENSMUSG00000002660(gene)|ensembl:ENSMUST00000002735(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR029045|interpro:IPR033135|mint:O88696 - - function:Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HU7Bj/nbET5gchsAsu7GlQ93pqs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P35762 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8329767|intact:MINT-4090262|uniprotkb:Q91V78|ensembl:ENSMUSP00000043768 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cd81_mouse(display_long)|uniprotkb:Cd81(gene name)|psi-mi:Cd81(display_short)|uniprotkb:Tapa1(gene name synonym)|uniprotkb:26 kDa cell surface protein TAPA-1(gene name synonym)|uniprotkb:Target of the antiproliferative antibody 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598416.1|go:"GO:1905521"(regulation of macrophage migration)|go:"GO:1905676"(positive regulation of adaptive immune memory response)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2001190"(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P35762|rcsb pdb:3X0F|reactome:R-MMU-198933|reactome:R-MMU-977606|ensembl:ENSMUSG00000037706(gene)|ensembl:ENSMUST00000037941(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031623"(receptor internalization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034238"(macrophage fusion)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072675"(osteoclast fusion)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:1903911"(positive regulation of receptor clustering)|go:"GO:1904352"(positive regulation of protein catabolic process in the vacuole) - - comment:mint|function:May play an important role in the regulation of lymphoma cell growth figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QJ25Y9J5X29IN4EYzRs9mYRuP7Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P07742 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8419105|intact:MINT-4121992|uniprotkb:Q91YM8|ensembl:ENSMUSP00000033283 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rir1_mouse(display_long)|uniprotkb:Rrm1(gene name)|psi-mi:Rrm1(display_short)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033129.2|ensembl:ENSMUSG00000030978(gene)|ensembl:ENSMUST00000033283(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|mint:P07742|reactome:R-MMU-499943 - - comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jFv8uoBWpbN0Kkxevtfo57/wg3A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q921H8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8330006|intact:MINT-1858351|ensembl:ENSMUSP00000042351 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:thika_mouse(display_long)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Acaa1a(gene name)|psi-mi:Acaa1a(display_short)|uniprotkb:Acaa1(gene name synonym)|uniprotkb:Beta-ketothiolase A(gene name synonym)|uniprotkb:Acetyl-CoA acyltransferase A(gene name synonym)|uniprotkb:Peroxisomal 3-oxoacyl-CoA thiolase A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_570934.1|refseq:XP_006511986.1|ensembl:ENSMUSG00000036138(gene)|ensembl:ENSMUST00000039784(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008775"(acetate CoA-transferase activity)|go:"GO:0010124"(phenylacetate catabolic process)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q921H8|reactome:R-MMU-2046106|reactome:R-MMU-390247|reactome:R-MMU-6798695|reactome:R-MMU-9033241 - - comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:A7f6/enaS9RJZ+DDXxVXXa/9vTU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91XB7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7455606|intact:MINT-152722|uniprotkb:Q9CWB2|ensembl:ENSMUSP00000025811 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:yif1a_mouse(display_long)|uniprotkb:Yif1a(gene name)|psi-mi:Yif1a(display_short)|uniprotkb:YIP1-interacting factor homolog A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080829.1|ensembl:ENSMUST00000025811(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|ensembl:ENSMUSG00000024875(gene)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005578(Hrf1) - - comment:mint|function:Possible role in transport between endoplasmic reticulum and Golgi figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HS9q4iJb3cXF5FKygB/0+zRahLU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80SZ7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8327431|uniprotkb:Q5I0W4|uniprotkb:P30670|uniprotkb:Q61015|intact:MINT-4095767|ensembl:ENSMUSP00000087485|ensembl:ENSMUSP00000114014 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gbg5_mouse(display_long)|uniprotkb:Gng5(gene name)|psi-mi:Gng5(display_short)|uniprotkb:Gngt5(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034448.2|refseq:XP_003945606.1|ensembl:ENSMUSG00000068523(gene)|ensembl:ENSMUST00000090031(transcript)|ensembl:ENSMUST00000118280(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|mint:Q80SZ7|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-500657 - - function:"Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction"|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RiKSjlVpDoFyBo8J1dD238/ju5810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BT60 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8392462|uniprotkb:Q5CZX9|intact:MINT-4091865|uniprotkb:Q5DU22|ensembl:ENSMUSP00000029885 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cpne3_mouse(display_long)|uniprotkb:Cpne3(gene name)|psi-mi:Cpne3(display_short)|uniprotkb:Kiaa0636(gene name synonym)|uniprotkb:Copine III(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_082045.1|ensembl:ENSMUSG00000028228(gene)|ensembl:ENSMUST00000029885(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|mint:Q8BT60|reactome:R-MMU-1483206|reactome:R-MMU-6798695 - - comment:mint|function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PWUkAdP1WMp+QwgAGfalwlLE0W410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CR47 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8387142|intact:MINT-4137964|uniprotkb:Q8BHT0|uniprotkb:Q9CYK0|uniprotkb:Q9JKF9|uniprotkb:Q9CRQ0|uniprotkb:A0JNU8|uniprotkb:Q9CS34|uniprotkb:Q8BHQ6|ensembl:ENSMUSP00000073161 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nsa2_mouse(display_long)|uniprotkb:Nsa2(gene name)|psi-mi:Nsa2(display_short)|uniprotkb:L-name-related protein 42(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:Tinp1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_067527.3|ensembl:ENSMUSG00000060739(gene)|ensembl:ENSMUST00000073456(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:Q9CR47 - - function:Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:JUZaWNzjyeYdjS4jAJKM0S/rhno10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9EST5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8357054|uniprotkb:Q566J4|intact:MINT-1869930|uniprotkb:B1AVH9|ensembl:ENSMUSP00000099990 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:an32b_mouse(display_long)|uniprotkb:Anp32b(gene name)|psi-mi:Anp32b(display_short)|uniprotkb:Pal31(gene name synonym)|uniprotkb:Proliferation-related acidic leucine-rich protein PAL31(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_570959.1|ensembl:ENSMUSG00000028333(gene)|ensembl:ENSMUST00000102926(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:Q9EST5 - - comment:mint|function:"Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pbIMOtV2hpOQfq1R1YLl2FK3nLc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9EQ06 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8366071|uniprotkb:Q8BR33|uniprotkb:Q8C7S0|uniprotkb:Q3U2P6|intact:MINT-1862554|ensembl:ENSMUSP00000031251 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dhb11_mouse(display_long)|uniprotkb:Pan1b(gene name synonym)|uniprotkb:Hsd17b11(gene name)|psi-mi:Hsd17b11(display_short)|uniprotkb:Dhrs8(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 11(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase XI(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 8(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_444492.1|ensembl:ENSMUSG00000029311(gene)|ensembl:ENSMUST00000031251(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006710"(androgen catabolic process)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|reactome:R-MMU-193144|mint:Q9EQ06 - - comment:mint|function:"Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+5AfbZgg7RLF6jHOu++HR77DJaI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P08032 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8350116|uniprotkb:B2RWX6|intact:MINT-85326|uniprotkb:P97502|ensembl:ENSMUSP00000027817 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:spta1_mouse(display_long)|uniprotkb:Spta1(gene name)|psi-mi:Spta1(display_short)|uniprotkb:Spna1(gene name synonym)|uniprotkb:Spta(gene name synonym)|uniprotkb:Erythroid alpha-spectrin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035595.2|ensembl:ENSMUSG00000026532(gene)|ensembl:ENSMUST00000027817(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036028|mint:P08032|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878 - - comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:uaswmTQnd1d+MrnYyCICUC3vTkM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70349 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8311513|ensembl:ENSMUSP00000020504|intact:MINT-1868587 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hint1_mouse(display_long)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym)|uniprotkb:Hint1(gene name)|psi-mi:Hint1(display_short)|uniprotkb:Hint(gene name synonym)|uniprotkb:Pkci(gene name synonym)|uniprotkb:Pkci1(gene name synonym)|uniprotkb:Prkcnh1(gene name synonym)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P70349|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|ensembl:ENSMUSG00000020267(gene)|ensembl:ENSMUST00000020504(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009154"(purine ribonucleotide catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:NP_032274.1 - - function:Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oC9NIOYuQEBtOmPu2ymihOKA68g10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q61503 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8366170|intact:MINT-4086307|uniprotkb:Q3U3S1|ensembl:ENSMUSP00000034992 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:5ntd_mouse(display_long)|uniprotkb:Nt5e(gene name)|psi-mi:Nt5e(display_short)|uniprotkb:Nt5(gene name synonym)|uniprotkb:Nte(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035981.1|ensembl:ENSMUSG00000032420(gene)|ensembl:ENSMUST00000034992(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046032"(ADP catabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046086"(adenosine biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0097060"(synaptic membrane)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR029052|interpro:IPR036907|mint:Q61503|reactome:R-MMU-196807|reactome:R-MMU-73621|reactome:R-MMU-74259 - - comment:mint|function:Hydrolyzes extracellular nucleotides into membrane permeable nucleosides figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Hr8FCil+qksk2i3M9KKPjWUJeAA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JII6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8321453|uniprotkb:Q9D0I7|uniprotkb:Q9D016|uniprotkb:Q9CQI5|intact:MINT-1869516|uniprotkb:Q9D0P3|uniprotkb:Q9D012|uniprotkb:Q9CT53|uniprotkb:Q9CQT8|ensembl:ENSMUSP00000030455 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ak1a1_mouse(display_long)|uniprotkb:Akr1a1(gene name)|psi-mi:Akr1a1(display_short)|uniprotkb:Akr1a4(gene name synonym)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:"Alcohol dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:Glucuronate reductase(gene name synonym)|uniprotkb:Glucuronolactone reductase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_067448.1|ensembl:ENSMUSG00000028692(gene)|ensembl:ENSMUST00000030455(transcript)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005829"(cytosol)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019726"("mevaldate reductase (NADPH) activity")|go:"GO:0019853"(L-ascorbic acid biosynthetic process)|go:"GO:0042840"(D-glucuronate catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0046185"(aldehyde catabolic process)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047939"(L-glucuronate reductase activity)|go:"GO:0047941"(glucuronolactone reductase activity)|go:"GO:0047956"(glycerol dehydrogenase [NADP+] activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:1990002"("methylglyoxal reductase (NADPH-dependent, acetol producing)")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044481|mint:Q9JII6|rcsb pdb:4GAC|reactome:R-MMU-156590|reactome:R-MMU-5661270 - - comment:mint|function:Catalyzes the NADPH-dependent reduction of a variety of aldehydes to their corresponding alcohols figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:kEvFTPRQrhIchD7oVZSNFUCDPho10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q62241 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8339212|intact:MINT-4133349|ensembl:ENSMUSP00000063976|ensembl:ENSMUSP00000156707 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ru1c_mouse(display_long)|uniprotkb:Snrpc(gene name)|psi-mi:Snrpc(display_short)|uniprotkb:Snrp1c(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035562.1|ensembl:ENSMUSG00000024217(gene)|ensembl:ENSMUST00000071006(transcript)|ensembl:ENSMUST00000232873(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005685"(U1 snRNP)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030627"(pre-mRNA 5'-splice site binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013085(Zinc finger, U1-C type)|interpro:IPR017340(U1 small nuclear ribonucleoprotein C)|interpro:IPR036236|mint:Q62241|reactome:R-MMU-72163 - - comment:mint|function:This protein is associated with snRNP U1 figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:sGzvv8+INqe3d+qAk/Y4656zOVs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q61468 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8402770|intact:MINT-4109628|ensembl:ENSMUSP00000158357|ensembl:ENSMUSP00000158474 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:msln_mouse(display_long)|uniprotkb:Msln(gene name)|psi-mi:Msln(display_short)|uniprotkb:Mes(gene name synonym)|uniprotkb:Mpf(gene name synonym)|uniprotkb:Pre-pro-megakaryocyte-potentiating factor(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_061345.1|refseq:XP_006524713.1|ensembl:ENSMUSG00000063011(gene)|ensembl:ENSMUST00000237359(transcript)|ensembl:ENSMUST00000238120(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR010335(Pre-pro-megakaryocyte potentiating factor precursor)|interpro:IPR026664|mint:Q61468|reactome:R-MMU-163125|reactome:R-MMU-381426|reactome:R-MMU-8957275 - - function:"Megakaryocyte-potentiating factor (MPF) may potentiate megakaryocyte colony formation"|function:Membrane-anchored forms may play a role in cellular adhesion|comment:mint figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:zq5aphNmph6Ecrx7PQTr3UJaJxU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P61327 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8317341|ensembl:ENSMUSP00000030348|intact:MINT-4101859|uniprotkb:P50606|uniprotkb:A2A8E0|uniprotkb:O35169 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mgn_mouse(display_long)|uniprotkb:Magoh(gene name)|psi-mi:Magoh(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001269666.1|ensembl:ENSMUSG00000028609(gene)|ensembl:ENSMUST00000030348(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61327|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957 - - comment:mint|function:"Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z0G9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-7158584|ensembl:ENSMUSP00000091799|uniprotkb:Q91X40|intact:MINT-113483 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cld3_mouse(display_long)|uniprotkb:Cldn3(gene name)|psi-mi:Cldn3(display_short)|uniprotkb:Cpetr2(gene name synonym)|uniprotkb:Clostridium perfringens enterotoxin receptor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000070473(gene)|ensembl:ENSMUST00000094245(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034331"(cell junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1905050"(positive regulation of metallopeptidase activity)|interpro:IPR003549(Claudin-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|rcsb pdb:6AKE|rcsb pdb:6AKF|rcsb pdb:6AKG|refseq:NP_034032.1|dip:DIP-40779N - - comment:mint|function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1NbVPFbbqYLPehRqqbLFoCG8SQI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QYF1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8381445|intact:MINT-1865554|uniprotkb:Q3UXM9|uniprotkb:Q9D0U5|ensembl:ENSMUSP00000124066 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rdh11_mouse(display_long)|uniprotkb:Rdh11(gene name)|psi-mi:Rdh11(display_short)|uniprotkb:Arsdr1(gene name synonym)|uniprotkb:Mdt1(gene name synonym)|uniprotkb:Psdr1(gene name synonym)|uniprotkb:Retinal reductase 1(gene name synonym)|uniprotkb:Prostate short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:Androgen-regulated short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:Short-chain aldehyde dehydrogenase(gene name synonym)|uniprotkb:Cell line MC/9.IL4-derived protein 1(gene name synonym)|uniprotkb:M42C60(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_067532.2|ensembl:ENSMUSG00000066441(gene)|ensembl:ENSMUST00000161204(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0033721"("aldehyde dehydrogenase (NADP+) activity")|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0102354"(11-cis-retinol dehydrogenase activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q9QYF1|reactome:R-MMU-2453902|reactome:R-MMU-5365859|reactome:R-MMU-975634 - - comment:mint|function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent all-trans-retinal reductase. Also involved in the metabolism of short-chain aldehydes figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PJl3jmTF3mlcEm1IUWhDeI7aTjM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BGT7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8373185|intact:MINT-4135289|uniprotkb:Q4QQL0|ensembl:ENSMUSP00000025997|ensembl:ENSMUSP00000157540 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:spf30_mouse(display_long)|uniprotkb:Smndc1(gene name)|psi-mi:Smndc1(display_short)|uniprotkb:Smnr(gene name synonym)|uniprotkb:Spf30(gene name synonym)|uniprotkb:30 kDa splicing factor SMNrp(gene name synonym)|uniprotkb:SMN-related protein(gene name synonym)|uniprotkb:Survival motor neuron domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_766017.1|refseq:XP_006527504.1|ensembl:ENSMUSG00000025024(gene)|ensembl:ENSMUST00000025997(transcript)|ensembl:ENSMUST00000237529(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q8BGT7|reactome:R-MMU-72163 - - comment:mint|function:Necessary for spliceosome assembly. Overexpression causes apoptosis figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:SLCltaGwLZToRzy3KKYJR4dPlHE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O54790 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-8339457|intact:MINT-4101043|ensembl:ENSMUSP00000053899|ensembl:ENSMUSP00000101786|ensembl:ENSMUSP00000101787|ensembl:ENSMUSP00000101788 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mafg_mouse(display_long)|uniprotkb:Mafg(gene name)|psi-mi:Mafg(display_short)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog G(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034886.1|refseq:XP_017169797.1|refseq:XP_017169798.1|refseq:XP_017169799.1|refseq:XP_017169800.1|dip:DIP-46344N|ensembl:ENSMUSG00000051510(gene)|ensembl:ENSMUST00000058162(transcript)|ensembl:ENSMUST00000106180(transcript)|ensembl:ENSMUST00000106181(transcript)|ensembl:ENSMUST00000106182(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030534"(adult behavior)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR028551|mint:O54790|rcsb pdb:1K1V|rcsb pdb:3A5T|reactome:R-MMU-983231 - - comment:mint|function:"Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2" figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Czx9HKnnVMTJudPKQ9JEJtUo+c810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:F6RND9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9990149|ensembl:ENSMUSP00000119562 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:f6rnd9_mouse(display_long)|uniprotkb:Mprip(gene name)|psi-mi:Mprip(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUST00000133861(transcript)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|ensembl:ENSMUSG00000005417(gene) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7HVTbOAhFHsprqbrLoMtNV34iqQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99104 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-400199|uniprotkb:E9PUE5|ensembl:ENSMUSP00000116028 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:myo5a_mouse(display_long)|uniprotkb:Myo5a(gene name)|psi-mi:Myo5a(display_short)|uniprotkb:Dilute(gene name synonym)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034994.2|ensembl:ENSMUSG00000034593(gene)|ensembl:ENSMUST00000123128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0001726"(ruffle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007601"(visual perception)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014046"(dopamine secretion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031982"(vesicle)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042476"(odontogenesis)|go:"GO:0042552"(myelination)|go:"GO:0042641"(actomyosin)|go:"GO:0042642"(actomyosin, myosin complex part)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099089"(establishment of endoplasmic reticulum localization to postsynapse)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099640"(axo-dendritic protein transport)|go:"GO:0150103"(reactive gliosis)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|go:"GO:0030318"(melanocyte differentiation)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR037988|mint:Q99104|rcsb pdb:2IX7|rcsb pdb:3WB8|rcsb pdb:4KP3|rcsb pdb:4ZLK|rcsb pdb:6KU0|reactome:R-MMU-2029482|interpro:IPR002710(Dilute)|go:"GO:0030141"(secretory granule)|dip:DIP-29542N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8QtBlLL4DqB3An4CoCFVmvBEXBg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WUM5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-773740|uniprotkb:Q8C2C3|uniprotkb:Q9DBA3|uniprotkb:Q9DCI8|ensembl:ENSMUSP00000065113 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:suca_mouse(display_long)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)|uniprotkb:Suclg1(gene name)|psi-mi:Suclg1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_063932.2|ensembl:ENSMUSG00000052738(gene)|ensembl:ENSMUST00000064740(transcript)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:Q9WUM5|reactome:R-MMU-71403 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Bb1b4P5dXlGyek/f6p8+X0Dbzt010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P97376 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-5692339|uniprotkb:Q99M42|ensembl:ENSMUSP00000033999 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:frg1_mouse(display_long)|uniprotkb:Frg1(gene name)|psi-mi:Frg1(display_short)|uniprotkb:FSHD region gene 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_038550.2|refseq:XP_017168059.1|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0007517"(muscle organ development)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0030018"(Z disc)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010414(FRG1-like)|rcsb pdb:2YUG|ensembl:ENSMUSG00000031590(gene)|ensembl:ENSMUST00000033999(transcript) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/MMx1dXxEmlGynDkKwB9E86nOzw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CHY6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3043877|ensembl:ENSMUSP00000112164|ensembl:ENSMUSP00000148474|uniprotkb:Q8BTQ2|uniprotkb:Q8VEC9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:p66a_mouse(display_long)|uniprotkb:Gatad2a(gene name)|psi-mi:Gatad2a(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000036180(gene)|ensembl:ENSMUST00000116463(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001842"(neural fold formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0012501"(programmed cell death)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR032346|interpro:IPR040386|mint:Q8CHY6|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|ensembl:ENSMUST00000212478(transcript)|refseq:XP_011240597.1|refseq:NP_001106817.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Sl8kjbcfcvx+CKED3wLD9HvAEjs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922F4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2310445|ensembl:ENSMUSP00000001513 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tbb6_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080749.2|ensembl:ENSMUSG00000001473(gene)|ensembl:ENSMUST00000001513(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q922F4|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P99024 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D883 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6876958|ensembl:ENSMUSP00000014684|uniprotkb:Q564E4|uniprotkb:Q99LX2|uniprotkb:Q9CZ98 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:u2af1_mouse(display_long)|uniprotkb:U2af1(gene name)|psi-mi:U2af1(display_short)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005681"(spliceosomal complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050733"(RS domain binding)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR009145(U2 auxiliary factor small subunit)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9D883|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|ensembl:ENSMUSG00000061613(gene)|ensembl:ENSMUST00000014684(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|refseq:NP_001157241.1|refseq:NP_077149.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:W7mwbEH9hsB3BfLk5hmV+Uj9N4410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UWW6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989247|uniprotkb:Q3TCF5 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ga2l3_mouse(display_long)|uniprotkb:Gas2l3(gene name)|psi-mi:Gas2l3(display_short)|uniprotkb:Growth arrest-specific protein 2-like 3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR029932|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003108(Growth-arrest-specific protein 2)|refseq:NP_001028503.2|refseq:NP_001073345.1|refseq:NP_001271273.1|refseq:XP_011241747.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR036534|interpro:IPR036872 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:u9LushafXztbk6+IA3A2/18dqJY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80UW8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6094615|ensembl:ENSMUSP00000004786 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rpab1_mouse(display_long)|uniprotkb:Polr2e(gene name)|psi-mi:Polr2e(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079830.2|ensembl:ENSMUSG00000004667(gene)|ensembl:ENSMUST00000004786(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-77075|reactome:R-MMU-9018519 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:NKA6+5grFwQn41K1TqXFHmmyXcs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BGS1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4283324|uniprotkb:Q3TJG0|uniprotkb:Q69ZG8|uniprotkb:Q8BSC9|uniprotkb:Q99KZ8|ensembl:ENSMUSP00000058966 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:e41l5_mouse(display_long)|uniprotkb:Epb4.1l5(gene name synonym)|uniprotkb:Kiaa1548(gene name synonym)|uniprotkb:Epb41l5(gene name)|psi-mi:Epb41l5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0001756"(somitogenesis)|refseq:NP_001106887.1|refseq:NP_663481.2|refseq:XP_006529460.1|refseq:XP_006529461.1|refseq:XP_006529463.1|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0048319"(axial mesoderm morphogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|ensembl:ENSMUSG00000026383(gene)|ensembl:ENSMUST00000052404(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|interpro:IPR030694|mint:Q8BGS1|reactome:R-MMU-6794361|interpro:IPR035963 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pt6yMNx5+txA950Eal6TthTO5sM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D115 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989305|ensembl:ENSMUSP00000154190|ensembl:ENSMUSP00000154192|ensembl:ENSMUSP00000154243|ensembl:ENSMUSP00000077996 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:zn706_mouse(display_long)|uniprotkb:Znf706(gene name)|psi-mi:Znf706(display_short)|uniprotkb:Zfp706(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080797.1|ensembl:ENSMUSG00000062397(gene)|ensembl:ENSMUST00000078976(transcript)|ensembl:ENSMUST00000226453(transcript)|ensembl:ENSMUST00000226671(transcript)|ensembl:ENSMUST00000228275(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|interpro:IPR007513(Four F5 protein)|interpro:IPR026939|mint:Q9D115|reactome:R-MMU-212436 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AfBUOZ8pX25JaH2JyvHVCtEf23410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O55029 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-642302|uniprotkb:Q3U5Z9|ensembl:ENSMUSP00000035033 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:copb2_mouse(display_long)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:Copb2(gene name)|psi-mi:Copb2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_056642.1|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434|ensembl:ENSMUSG00000032458(gene)|ensembl:ENSMUST00000035033(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:O55029|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:gNG1OpF+jXIVk7jLKcvbyd13VW810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UQJ7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989318 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3uqj7_mouse(display_long)|uniprotkb:Dnajc13(gene name)|psi-mi:Dnajc13(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1902954"(regulation of early endosome to recycling endosome transport)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR036869 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:c49f1TzhUIpMQSKBWL+19DU2kU410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WTM5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2549911|ensembl:ENSMUSP00000103400|ensembl:ENSMUSP00000147502 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ruvb2_mouse(display_long)|uniprotkb:Ruvbl2(gene name)|psi-mi:Ruvbl2(display_short)|uniprotkb:p47 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000003868(gene)|ensembl:ENSMUST00000107771(transcript)|ensembl:ENSMUST00000211214(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051117"(ATPase binding)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9WTM5|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_035434.1|refseq:XP_006540785.1|refseq:XP_006540786.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:tHnjngaz5qWy9sPXagFLp3TRDtA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P42932 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772400|ensembl:ENSMUSP00000026704 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tcpq_mouse(display_long)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Cct8(gene name)|psi-mi:Cct8(display_short)|uniprotkb:Cctq(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033970.3|ensembl:ENSMUSG00000025613(gene)|ensembl:ENSMUST00000026704(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P42932|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:p3GMjguKvbAdbh4NkDyU8W4nr1E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P58242 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989230|ensembl:ENSMUSP00000030709 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:asm3b_mouse(display_long)|uniprotkb:Smpdl3b(gene name)|psi-mi:Smpdl3b(display_short)|uniprotkb:Asml3b(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598649.1|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016798"(hydrolase activity, acting on glycosyl bonds)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046466"(membrane lipid catabolic process)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR017064(Acid sphingomyelinase-like phosphodiesterase, predicted)|interpro:IPR029052|interpro:IPR041805|rcsb pdb:5KAR|rcsb pdb:5KAS|go:"GO:0006954"(inflammatory response)|ensembl:ENSMUSG00000028885(gene)|ensembl:ENSMUST00000030709(transcript)|go:"GO:0004767"(sphingomyelin phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006685"(sphingomyelin catabolic process) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:V/kK5ODgngr6Z8FhRpclbH3a0FU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CI43 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4286253|ensembl:ENSMUSP00000026428 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:myl6b_mouse(display_long)|uniprotkb:Myl6b(gene name)|psi-mi:Myl6b(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_758463.1|ensembl:ENSMUSG00000039824(gene)|ensembl:ENSMUST00000026428(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|reactome:R-MMU-445355|refseq:XP_017169402.1|refseq:XP_017169403.1|refseq:XP_017169404.1|refseq:XP_017169405.1|refseq:XP_017169406.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:SqvRDqPjO60DFT+dkkbnosxuBnk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6P5H2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2899462|ensembl:ENSMUSP00000088493|uniprotkb:A1E2I2|uniprotkb:Q80X00|uniprotkb:Q8BPH7|uniprotkb:Q9CV43|uniprotkb:Q9R0C4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nest_mouse(display_long)|uniprotkb:Nes(gene name)|psi-mi:Nes(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUST00000090973(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030844"(positive regulation of intermediate filament depolymerization)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048858"(cell projection morphogenesis)|ensembl:ENSMUSG00000004891(gene)|go:"GO:0072089"(stem cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR018039|interpro:IPR031211|interpro:IPR039008|refseq:NP_057910.3 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:c9UQwTSScUEP6n41WzoQiEzEyN410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P80314 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UIL6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989345|uniprotkb:B6RSP2|uniprotkb:B6RSP3|uniprotkb:Q3TUE4|uniprotkb:Q5XG70|uniprotkb:Q8BYE3|ensembl:ENSMUSP00000138214 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pkha7_mouse(display_long)|uniprotkb:Plekha7(gene name)|psi-mi:Plekha7(display_short)|uniprotkb:Hadp1(gene name synonym)|uniprotkb:Heart adapter protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_766331.1|ensembl:ENSMUSG00000045659|ensembl:ENSMUSG00000045659|ensembl:ENSMUSG00000045659|ensembl:ENSMUSG00000045659|refseq:NP_001292119.1|refseq:NP_001292114.1|refseq:NP_001292115.1|refseq:NP_001292118.1|ensembl:ENSMUSG00000045659(gene)|ensembl:ENSMUST00000182487(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BqUxqTeODKlgaIVSauEUblhcdZs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P12382 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-400474|uniprotkb:Q8VDX7|ensembl:ENSMUSP00000020522 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pfkal_mouse(display_long)|uniprotkb:Pfkl(gene name)|psi-mi:Pfkl(display_short)|uniprotkb:Pfk-l(gene name synonym)|uniprotkb:Pfkb(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032852.2|ensembl:ENSMUSG00000020277(gene)|ensembl:ENSMUST00000020522(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P12382|reactome:R-MMU-6798695|reactome:R-MMU-70171 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WlBnp+GuMEVU1PRrdVHwJxZi5gE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQQ4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989405|uniprotkb:Q9DAD7|ensembl:ENSMUSP00000021379 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gemi2_mouse(display_long)|uniprotkb:Gemin2(gene name)|psi-mi:Gemin2(display_short)|uniprotkb:Sip1(gene name synonym)|uniprotkb:Component of gems 2(gene name synonym)|uniprotkb:Survival of motor neuron protein-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079932.2|ensembl:ENSMUSG00000060121(gene)|ensembl:ENSMUST00000021379(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR017364(Survival of motor neuron protein interacting, gemin2)|interpro:IPR035426|reactome:R-MMU-191859 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:O/XmjNomuDGT/9w6+0dyHVuvaEM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TWW8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989273|uniprotkb:Q3UJV5|uniprotkb:Q921K3|uniprotkb:Q9DBP1|ensembl:ENSMUSP00000119065 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:srsf6_mouse(display_long)|uniprotkb:Srsf6(gene name)|psi-mi:Srsf6(display_short)|uniprotkb:Sfrs6(gene name synonym)|uniprotkb:Srp55(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080775.3|ensembl:ENSMUSG00000016921(gene)|ensembl:ENSMUST00000130411(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|reactome:R-MMU-159236|go:"GO:0003723"(RNA binding)|reactome:R-MMU-72165|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-72163 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/l6R/Dpz2RgXmBU+qQerM46ZnRU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P47915 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-642703|ensembl:ENSMUSP00000080203|ensembl:ENSMUSP00000096592|ensembl:ENSMUSP00000117834 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rl29_mouse(display_long)|uniprotkb:Rpl29(gene name)|psi-mi:Rpl29(display_short)|uniprotkb:Rpl43(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033108.1|refseq:XP_990228.1|refseq:XP_006511723.1|ensembl:ENSMUST00000098994(transcript)|ensembl:ENSMUST00000150576(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47915|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUST00000059802(transcript)|ensembl:ENSMUSG00000048758(gene)|refseq:NP_001311462.1|refseq:NP_001311463.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Eo9fBkLLj3pU2/Rd3Z/HvzBHxSs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UKW2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989454 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3ukw2_mouse(display_long) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_001300863.1|go:"GO:0005509"(calcium ion binding) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:OD7RB+7zzPaYTDYcQexXWAnSh9g10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CG47 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6921575|ensembl:ENSMUSP00000047872|uniprotkb:Q8BTS7|uniprotkb:Q8BTY9|uniprotkb:Q99K21 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:smc4_mouse(display_long)|uniprotkb:Smc4(gene name)|psi-mi:Smc4(display_short)|uniprotkb:Capc(gene name synonym)|uniprotkb:Smc4l1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_006502109.1|ensembl:ENSMUSG00000034349(gene)|ensembl:ENSMUST00000042901(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q8CG47|rcsb pdb:3L51|reactome:R-MMU-2299718|reactome:R-MMU-2514853|refseq:NP_598547.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:SF4vyf1kJkH5VuPPgdXoHrPCxaA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6DFW4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6260951|ensembl:ENSMUSP00000140250|uniprotkb:Q8C8Y7|uniprotkb:Q3UZA3|uniprotkb:O70396|uniprotkb:Q3UYX9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nop58_mouse(display_long)|uniprotkb:MSSP(gene name synonym)|uniprotkb:Nol5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:SIK-similar protein(gene name synonym)|uniprotkb:Nop58(gene name)|psi-mi:Nop58(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000026020(gene)|ensembl:ENSMUST00000191142(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q6DFW4|reactome:R-MMU-4570464|reactome:R-MMU-6791226|refseq:NP_061356.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:gx/F5iCI7SIdIqpZobsk4CcPd/I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P60335 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-309059|ensembl:ENSMUSP00000054863 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VEK3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-529674|uniprotkb:Q9R205|uniprotkb:G3XA10|ensembl:ENSMUSP00000047571 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hnrpu_mouse(display_long)|uniprotkb:Hnrpu(gene name synonym)|uniprotkb:Hnrnpu(gene name)|psi-mi:Hnrnpu(display_short)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_017177162.1|refseq:XP_017177163.1|refseq:NP_058085.2|refseq:XP_017177161.1|dip:DIP-34257N|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q8VEK3|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000039630(gene)|ensembl:ENSMUST00000037748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ONBrFPHIT3aP6XnUgJMf4qiu8VQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q810D6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989430|uniprotkb:G3UVT6|uniprotkb:Q922H3|ensembl:ENSMUSP00000103351|ensembl:ENSMUSP00000116252 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:grwd1_mouse(display_long)|uniprotkb:Grwd1(gene name)|psi-mi:Grwd1(display_short)|uniprotkb:A301(gene name synonym)|uniprotkb:Protein A301(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_700468.2|ensembl:ENSMUSG00000053801(gene)|ensembl:ENSMUST00000107723(transcript)|ensembl:ENSMUST00000131384(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:joqRwDRwjLXJxxLLknUuhYsNRUY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QYJ0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772431|ensembl:ENSMUSP00000034138 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dnja2_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short)|uniprotkb:mDj3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062768.1|ensembl:ENSMUSG00000031701(gene)|ensembl:ENSMUST00000034138(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q9QYJ0|reactome:R-MMU-3371497 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ZYn3t1WpFrPa82gsMHxjaQRPr3k10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q7TQG1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989391|uniprotkb:Q8K0J5|ensembl:ENSMUSP00000048214 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pkha6_mouse(display_long)|uniprotkb:Plekha6(gene name)|psi-mi:Plekha6(display_short)|uniprotkb:Pepp3(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_891846.1|ensembl:ENSMUSG00000041757(gene)|ensembl:ENSMUST00000038295(transcript)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR040392|reactome:R-MMU-1660499 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:yiBOLmuEnCw6O4zx0EHYexx/pcw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8K2T1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989325|uniprotkb:Q8BVF0|uniprotkb:Q9CZP2|ensembl:ENSMUSP00000078132 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nmrl1_mouse(display_long)|uniprotkb:Nmral1(gene name)|psi-mi:Nmral1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001277690.1|refseq:NP_001277691.1|refseq:NP_001277692.1|refseq:NP_080669.1|ensembl:ENSMUSG00000063445(gene)|ensembl:ENSMUST00000079130(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036291|reactome:R-MMU-70635|interpro:IPR008030(NmrA-like) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Nu/flWLp6q6bma0LicTfQmE1tMQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62806 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6ZWX6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P58771 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-298478|uniprotkb:P02558|uniprotkb:P19354|uniprotkb:P46902|uniprotkb:P99034|ensembl:ENSMUSP00000109315 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tpm1_mouse(display_long)|uniprotkb:Tpm-1(gene name synonym)|uniprotkb:Tpma(gene name synonym)|uniprotkb:Tpm1(gene name)|psi-mi:Tpm1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000032366(gene)|ensembl:ENSMUST00000113685(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051693"(actin filament capping)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000533(Tropomyosin)|mint:P58771|rcsb pdb:7NEP|reactome:R-MMU-390522|reactome:R-MMU-445355|go:"GO:0003779"(actin binding)|refseq:NP_001157720.1|refseq:NP_077745.2|dip:DIP-300N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:d/imATvus0XZvr7i//2MtbXZ7Pw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99PM9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-644712|ensembl:ENSMUSP00000060202 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:uck2_mouse(display_long)|uniprotkb:Uridine monophosphokinase 2(gene name synonym)|uniprotkb:Cytidine monophosphokinase 2(gene name synonym)|uniprotkb:Uck2(gene name)|psi-mi:Uck2(display_short)|uniprotkb:Umpk(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_109649.1|ensembl:ENSMUSG00000026558(gene)|ensembl:ENSMUST00000053686(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR027417|interpro:IPR029925|reactome:R-MMU-73614|interpro:IPR006083(Phosphoribulokinase/uridine kinase) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:E+lz+mNwgjWmI4Lgx8J9eEuoxRY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q7TSZ8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-5691985|uniprotkb:Q80X97|uniprotkb:Q9CZ72|ensembl:ENSMUSP00000001975 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nacc1_mouse(display_long)|uniprotkb:Nacc1(gene name)|psi-mi:Nacc1(display_short)|uniprotkb:Btbd14b(gene name synonym)|uniprotkb:Nac1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein 14B(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080064.3|refseq:XP_006531355.1|refseq:XP_006531356.1|refseq:XP_006531357.1|dip:DIP-29930N|ensembl:ENSMUSG00000001910(gene)|ensembl:ENSMUST00000001975(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR018379|mint:Q7TSZ8 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Mp3o/oidyfj6U+OTJwTb2WP4Q3Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TH77 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989220 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3th77_mouse(display_long)|uniprotkb:Numa1(gene name)|psi-mi:Numa1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR026650|go:"GO:0000139"(Golgi membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qfnv2SKO0olYF6BYFtCPe/PSCbg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P14685 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-992014|uniprotkb:Q3TP95|uniprotkb:Q99LL7|ensembl:ENSMUSP00000017365 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psmd3_mouse(display_long)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:Transplantation antigen P91A(gene name synonym)|uniprotkb:Tum-P91A antigen(gene name synonym)|uniprotkb:Tstap91a(gene name synonym)|uniprotkb:Psmd3(gene name)|psi-mi:Psmd3(display_short)|uniprotkb:P91a(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033465.1|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-MMU-5610785|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|reactome:R-MMU-1169091|reactome:R-MMU-5632684|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-5658442|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-5668541|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-5676590|reactome:R-MMU-2467813|reactome:R-MMU-5687128|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-6798695|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-68827|ensembl:ENSMUSG00000017221(gene)|ensembl:ENSMUST00000017365(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WUwE+HYUn3TfD5w+LPjn5ouQSCQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q04750 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6666222|ensembl:ENSMUSP00000105094|uniprotkb:A2A4B7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:top1_mouse(display_long)|uniprotkb:Top1(gene name)|psi-mi:Top1(display_short)|uniprotkb:Top-1(gene name synonym)|uniprotkb:DNA topoisomerase I(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000070544(gene)|ensembl:ENSMUST00000109468(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0003682"(chromatin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|reactome:R-MMU-4615885|mint:Q04750|refseq:NP_033434.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:nY84yAtfGCI/k+B2u3mM151r+zU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62743 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1033702|uniprotkb:P70626|uniprotkb:P97626|uniprotkb:Q00380|ensembl:ENSMUSP00000083281 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ap2s1_mouse(display_long)|uniprotkb:Ap2s1(gene name)|psi-mi:Ap2s1(display_short)|uniprotkb:Ap17(gene name synonym)|uniprotkb:Claps2(gene name synonym)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3b(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000008036(gene)|ensembl:ENSMUST00000086112(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|mint:P62743|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|refseq:NP_941015.2|dip:DIP-37505N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TF18 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988547 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tf18_mouse(display_long)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR038650|interpro:IPR001357(BRCT)|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR012982(PADR1)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008893(WGR)|interpro:IPR001510(Zinc finger, PARP-type)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051287"(NAD binding)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:EapUAURaGmMphl+ltIyKDM39X6010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q61686 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q01320 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-642809|uniprotkb:E9PX08|ensembl:ENSMUSP00000068896 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:top2a_mouse(display_long)|uniprotkb:DNA topoisomerase II, alpha isozyme(gene name synonym)|uniprotkb:Top2a(gene name)|psi-mi:Top2a(display_short)|uniprotkb:Top2(gene name synonym)|uniprotkb:Top-2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_006533216.1|refseq:NP_035753.2|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:Q01320|reactome:R-MMU-4615885|interpro:IPR020568|ensembl:ENSMUSG00000020914(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0006265"(DNA topological change)|go:"GO:0006266"(DNA ligation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|ensembl:ENSMUST00000068031(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048511"(rhythmic process)|go:"GO:0051309"(female meiosis chromosome separation)|go:"GO:1905463"(negative regulation of DNA duplex unwinding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|go:"GO:0030263"(apoptotic chromosome condensation)|dip:DIP-40621N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4bT7YxXbxkbqULDvXoFRreoX9Gs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R323 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-529792|ensembl:ENSMUSP00000039621 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rfc3_mouse(display_long)|uniprotkb:Activator 1 subunit 3(gene name synonym)|uniprotkb:Replication factor C 38 kDa subunit(gene name synonym)|uniprotkb:Activator 1 38 kDa subunit(gene name synonym)|uniprotkb:Rfc3(gene name)|psi-mi:Rfc3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081285.1|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473|ensembl:ENSMUSG00000033970(gene)|ensembl:ENSMUST00000038131(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:A8JvnEC8Eg1fhQp8+Zs1OFqYQK010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O09172 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988608|ensembl:ENSMUSP00000029769|ensembl:ENSMUSP00000136987 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gsh0_mouse(display_long)|uniprotkb:Gclm(gene name)|psi-mi:Gclm(display_short)|uniprotkb:Glclr(gene name synonym)|uniprotkb:GCS light chain(gene name synonym)|uniprotkb:Gamma-ECS regulatory subunit(gene name synonym)|uniprotkb:Gamma-glutamylcysteine synthetase regulatory subunit(gene name synonym)|uniprotkb:Glutamate--cysteine ligase modifier subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032155.1|ensembl:ENSMUSG00000028124(gene)|ensembl:ENSMUST00000029769(transcript)|ensembl:ENSMUST00000178826(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0006534"(cysteine metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0014823"(response to activity)|go:"GO:0017109"(glutamate-cysteine ligase complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035226"(glutamate-cysteine ligase catalytic subunit binding)|go:"GO:0035229"(positive regulation of glutamate-cysteine ligase activity)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0042493"|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0097069"(cellular response to thyroxine stimulus)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR023210|interpro:IPR032963|interpro:IPR036812|reactome:R-MMU-174403 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+9WB1EzN4btR+OMZxKwAUIuzO0M10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BUR9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2553237|ensembl:ENSMUSP00000037557 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mzt1_mouse(display_long)|uniprotkb:Mzt1(gene name)|psi-mi:Mzt1(display_short)|uniprotkb:Mozart1(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUST00000042662(transcript)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0031021"(interphase microtubule organizing center)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0051415"(microtubule nucleation by interphase microtubule organizing center)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR022214|mint:Q8BUR9|reactome:R-MMU-380270|reactome:R-MMU-380320|ensembl:ENSMUSG00000033186(gene)|refseq:NP_780454.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:a686Bpxk37Kl0gKKTz14f6sq6s410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P10711 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988575|uniprotkb:P10712|uniprotkb:P23713|ensembl:ENSMUSP00000080266 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tcea1_mouse(display_long)|uniprotkb:Tcea1(gene name)|psi-mi:Tcea1(display_short)|uniprotkb:Tceat(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein 1(gene name synonym)|uniprotkb:Transcription elongation factor TFIIS.o(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001153222.1|refseq:NP_001153223.1|refseq:NP_035671.1|ensembl:ENSMUSG00000033813(gene)|ensembl:ENSMUST00000081551(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|go:"GO:0030218"(erythrocyte differentiation)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR017923|interpro:IPR035100|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR035441|interpro:IPR036575|mint:P10711|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-75955 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8EelzoMlCCdII18TQKPxJQOwZh010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q64511 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2325586|uniprotkb:Q7TQG4|ensembl:ENSMUSP00000017629 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:top2b_mouse(display_long)|uniprotkb:Top2b(gene name)|psi-mi:Top2b(display_short)|uniprotkb:DNA topoisomerase II, beta isozyme(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033435.2|ensembl:ENSMUSG00000017485(gene)|ensembl:ENSMUST00000017629(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0007409"(axonogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030900"(forebrain development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071318"(cellular response to ATP)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR028467|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:Q64511|reactome:R-MMU-4615885 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:dB5M5wdu6YqBC7uBMe34toA5ISQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q920B9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2549823|uniprotkb:Q3TZ48|uniprotkb:Q3UFH0|uniprotkb:Q921H4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sp16h_mouse(display_long)|uniprotkb:Supt16h(gene name)|psi-mi:Supt16h(display_short)|uniprotkb:Fact140(gene name synonym)|uniprotkb:Factp140(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:Supt16(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|interpro:IPR029148|reactome:R-MMU-6804756|reactome:R-MMU-75955|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|refseq:NP_291096.2|dip:DIP-55972N|mint:Q920B9 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qcl0ckY0w3tIem/ezLyPtHVUnZA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91VE6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-5307250|uniprotkb:Q8BMV9|uniprotkb:Q8BVL4|ensembl:ENSMUSP00000027626 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mk67i_mouse(display_long)|uniprotkb:Nifk(gene name)|psi-mi:Nifk(display_short)|uniprotkb:Mki67ip(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080748.3|ensembl:ENSMUST00000027626(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q91VE6|ensembl:ENSMUSG00000026377(gene) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WzoNlKj1SWWABD6uJQmAcH50g9M10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q64364 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1202287|uniprotkb:Q4U255|uniprotkb:Q9QXC7|uniprotkb:Q9R051|ensembl:ENSMUSP00000102748 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arf_mouse(display_long)|uniprotkb:Cdkn2a(gene name)|psi-mi:Cdkn2a(display_short)|uniprotkb:p19ARF(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034007.1|go:"GO:2000435"(negative regulation of protein neddylation)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|rcsb pdb:1HN3|ensembl:ENSMUSG00000044303(gene)|ensembl:ENSMUST00000107131(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001652"(granular component)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008544"(epidermis development)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090399"(replicative senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000346"(negative regulation of hepatocyte proliferation)|go:"GO:0090398"(cellular senescence)|dip:DIP-24169N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BhH/8naGepx1virLgxpw7IWRv6A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JHI7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988220|uniprotkb:Q9CSZ2|ensembl:ENSMUSP00000029269 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:exos9_mouse(display_long)|uniprotkb:Exosc9(gene name)|psi-mi:Exosc9(display_short)|uniprotkb:Pmscl1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062266.1|ensembl:ENSMUSG00000027714(gene)|ensembl:ENSMUST00000029269(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226|go:"GO:0034473"(U1 snRNA 3'-end processing) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:k5rc3PbcJlOVJB1S1macbdlEj1o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q497T2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988500 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q497t2_mouse(display_long)|uniprotkb:Ccnc(gene name)|psi-mi:Ccnc(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR013763(Cyclin-related)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR028367|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|interpro:IPR043198|interpro:IPR036915 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:IDOq00X/KgsD8q0acZGXbTmnWAs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:B0LM42 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988402|ensembl:ENSMUSP00000136623 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:b0lm42_mouse(display_long)|uniprotkb:Gm21992(gene name)|psi-mi:Gm21992(display_short)|uniprotkb:Rbm14(gene name synonym)|uniprotkb:Rbm4 fusion(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001277057.1|ensembl:ENSMUSG00000096370(gene)|ensembl:ENSMUST00000179909(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR035979|interpro:IPR036875 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:GLSKe75dS1WgX2MHetUmD8mZhnA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R1J3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988070|uniprotkb:Q921T6|uniprotkb:E9QQ14|ensembl:ENSMUSP00000022121 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:zchc9_mouse(display_long)|uniprotkb:Zcchc9(gene name)|psi-mi:Zcchc9(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_663428.2|ensembl:ENSMUSG00000021621(gene)|ensembl:ENSMUST00000022121(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042246 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PxoakMalOoHawe1Vh9EN7/dHbm810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P47801 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988090|ensembl:ENSMUSP00000032330|ensembl:ENSMUSP00000107538|ensembl:ENSMUSP00000145069 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:emp1_mouse(display_long)|uniprotkb:Emp1(gene name)|psi-mi:Emp1(display_short)|uniprotkb:Tmp(gene name synonym)|uniprotkb:Tumor-associated membrane protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001275556.1|refseq:NP_001275557.1|refseq:NP_034258.1|refseq:XP_006505565.1|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20)|ensembl:ENSMUSG00000030208(gene)|ensembl:ENSMUST00000032330(transcript)|ensembl:ENSMUST00000111907(transcript)|ensembl:ENSMUST00000205156(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032060"(bleb assembly)|interpro:IPR003932(Epithelial membrane protein EMP-1) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:v1lLnSsDA5MFnto/df6EFB4UPGI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6A4J8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1216254|uniprotkb:Q3UX92|uniprotkb:Q496Y5|uniprotkb:Q8BW01 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ubp7_mouse(display_long)|uniprotkb:Usp7(gene name)|psi-mi:Usp7(display_short)|uniprotkb:Hausp(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001003918.2|mint:Q6A4J8|dip:DIP-38603N|go:"GO:0001741"(XY body)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|interpro:IPR029346|interpro:IPR038765|reactome:R-MMU-5689880|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804757|reactome:R-MMU-8866652|reactome:R-MMU-8948747|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8+rOJLie2ABsU9vwlnVxcU342aQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UNH3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988487 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3unh3_mouse(display_long)|uniprotkb:Txnl1(gene name)|psi-mi:Txnl1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|go:"GO:0005737"(cytoplasm)|interpro:IPR036249|interpro:IPR037047 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:U4d08AzgySFkoLBlLZo//Eq/0ME10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CS42 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988112|uniprotkb:Q9CZA9|ensembl:ENSMUSP00000026839 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prps2_mouse(display_long)|uniprotkb:Prps2(gene name)|psi-mi:Prps2(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase II(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080938.1|refseq:NP_001300687.1|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0016301"(kinase activity)|go:"GO:0019003"(GDP binding)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043531"(ADP binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|reactome:R-MMU-73843|ensembl:ENSMUSG00000025742(gene)|ensembl:ENSMUST00000026839(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006167"(AMP biosynthetic process) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:LW20GVeKGhZIHMul2pNvZfov7Ak10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80TX4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988205 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q80tx4_mouse(display_long)|uniprotkb:mKIAA0577(gene name)|psi-mi:mKIAA0577(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BP5dr8Ltbyfb4Y8bUrn1arvEfPk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QYI4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988448|uniprotkb:Q8K037|ensembl:ENSMUSP00000020309|ensembl:ENSMUSP00000118088|ensembl:ENSMUSP00000122056 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:djb12_mouse(display_long)|uniprotkb:Dnajb12(gene name)|psi-mi:Dnajb12(display_short)|uniprotkb:mDj10(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_064349.2|ensembl:ENSMUSG00000020109|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034622"|go:"GO:0036503"(ERAD pathway)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENSMUSG00000020109(gene)|ensembl:ENSMUST00000020309(transcript)|ensembl:ENSMUST00000142819(transcript)|ensembl:ENSMUST00000146590(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:0QK+tyY7914Dy202L8XLA6vBjvg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P27641 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-822749|intact:EBI-1216334|uniprotkb:Q3TE46|uniprotkb:Q3TJT0|uniprotkb:Q3TN82|uniprotkb:Q80UT1|uniprotkb:Q8C4N6|uniprotkb:Q8K1K7|uniprotkb:Q9R169|ensembl:ENSMUSP00000027379 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:xrcc5_mouse(display_long)|uniprotkb:Xrcc5(gene name)|psi-mi:Xrcc5(display_short)|uniprotkb:G22p2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Ku autoantigen protein p86 homolog(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033559.2|ensembl:ENSMUSG00000026187(gene)|ensembl:ENSMUST00000027379(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P27641|reactome:R-MMU-5693571|reactome:R-MMU-6798695 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:481Y2f/7RfAolsvjFd4PhQpJD9810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C0K5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988380|uniprotkb:B2RSS4|uniprotkb:Q6P6K8|ensembl:ENSMUSP00000043370 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gdc_mouse(display_long)|uniprotkb:Slc25a16(gene name)|psi-mi:Slc25a16(display_short)|uniprotkb:Gda(gene name synonym)|uniprotkb:Mitochondrial solute carrier protein homolog(gene name synonym)|uniprotkb:Solute carrier family 25 member 16(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_780403.1|ensembl:ENSMUSG00000071253(gene)|ensembl:ENSMUST00000044977(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-MMU-196783 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RC/Vh/BRevsTNdR25vLVZpNSyg010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6P8K5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4284787 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q6p8k5_mouse(display_long)|uniprotkb:Zfp266(gene name)|psi-mi:Zfp266(display_short)|uniprotkb:5730601F06Rik(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:nUcpBNXjbjunGmWL5CynAmzKcrI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9EQ28 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-866783 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dpod3_mouse(display_long)|uniprotkb:DNA polymerase delta subunit p66(gene name synonym)|uniprotkb:Pold3(gene name)|psi-mi:Pold3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_006508212.2|interpro:IPR019038|reactome:R-MMU-5358565|reactome:R-MMU-5358606|interpro:IPR041913|reactome:R-MMU-110314|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174437|reactome:R-MMU-5651801|reactome:R-MMU-5656169|reactome:R-MMU-5685942|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:P8o/Q6EXh3pzHGl0f16WOnpqOdk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3V300 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988251|uniprotkb:O35232|uniprotkb:Q99LC7|ensembl:ENSMUSP00000032915 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:kif22_mouse(display_long)|uniprotkb:Kif22(gene name)|psi-mi:Kif22(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_663563.1|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR019821|interpro:IPR026986|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-983189|go:"GO:0072686"(mitotic spindle)|ensembl:ENSMUSG00000030677(gene)|ensembl:ENSMUST00000032915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0051310"(metaphase plate congression) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:GFzMAUzDCkLP0vjzvkhbY5btBeE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BWU5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988356|uniprotkb:Q99LN8 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:osgep_mouse(display_long)|uniprotkb:Osgep(gene name)|psi-mi:Osgep(display_short)|uniprotkb:N6-L-threonylcarbamoyladenine synthase(gene name synonym)|uniprotkb:O-sialoglycoprotein endopeptidase(gene name synonym)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep"(gene name synonym)|uniprotkb:tRNA threonylcarbamoyladenosine biosynthesis protein Osgep(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598437.2|interpro:IPR000905(Peptidase M22, glycoprotease)|interpro:IPR017861|interpro:IPR017860|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|go:"GO:0061711"("N(6)-L-threonylcarbamoyladenine synthase activity")|interpro:IPR043129|interpro:IPR034680 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:P1PEukL9e3wYOlkFpFAg8XnBmCs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BNI4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988284|uniprotkb:Q920I5|uniprotkb:Q99J12|ensembl:ENSMUSP00000117052 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:derl2_mouse(display_long)|uniprotkb:Derl2(gene name)|psi-mi:Derl2(display_short)|uniprotkb:Der2(gene name synonym)|uniprotkb:Flana(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:F-LANa(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001278075.1|refseq:NP_001278076.1|refseq:NP_001278077.1|refseq:NP_291040.1|ensembl:ENSMUSG00000018442(gene)|ensembl:ENSMUST00000143850(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-MMU-382556|reactome:R-MMU-5358346|go:"GO:0030176"(integral component of endoplasmic reticulum membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:TdVnEkE5Nl+1ZS2owcNOt+06QpQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C243 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988140 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q8c243_mouse(display_long)|uniprotkb:Ctsd(gene name)|psi-mi:Ctsd(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|go:"GO:0004190"(aspartic-type endopeptidase activity) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ez7xcQ+uMA0DZGoVrW930qkWKYA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WUR2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2794295|uniprotkb:Q99M61|uniprotkb:Q9D785|ensembl:ENSMUSP00000131735 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:eci2_mouse(display_long)|uniprotkb:Eci2(gene name)|psi-mi:Eci2(display_short)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Peci(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001103801.1|refseq:NP_035998.2|refseq:XP_006516736.1|refseq:XP_006516737.1|refseq:XP_006516738.1|refseq:XP_006516739.1|refseq:XP_006516740.1|ensembl:ENSMUSG00000021417(gene)|ensembl:ENSMUST00000171229(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:Q9WUR2|reactome:R-MMU-390247|reactome:R-MMU-9033241|go:"GO:0006635"(fatty acid beta-oxidation) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:nHPcS0mXXHwtPjuxHZLEOsf99sk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CG50 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988154|ensembl:ENSMUSP00000077716 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rab43_mouse(display_long)|uniprotkb:Rab43(gene name)|psi-mi:Rab43(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001034483.1|go:"GO:0035526"(retrograde transport, plasma membrane to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090382"(phagosome maturation)|go:"GO:1901998"(toxin transport)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-MMU-6811440|reactome:R-MMU-8873719|ensembl:ENSMUSG00000030055(gene)|ensembl:ENSMUST00000078647(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0019068"(virion assembly)|go:"GO:0030670"(phagocytic vesicle membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:3EcThtzOwZ4l7xfP94R3uPpw23410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80UM7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-773322|uniprotkb:Q9Z2W5|ensembl:ENSMUSP00000032114 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mogs_mouse(display_long)|uniprotkb:Glycoprotein-processing glucosidase I(gene name synonym)|uniprotkb:Glucosidase 1(gene name synonym)|uniprotkb:Mogs(gene name)|psi-mi:Mogs(display_short)|uniprotkb:Gcs1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_065644.2|ensembl:ENSMUSG00000030036(gene)|ensembl:ENSMUST00000032114(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q80UM7|rcsb pdb:5MHF - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FFdfFuK2tyQJgaQUB01LfWj0TIQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BHC4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988341|ensembl:ENSMUSP00000021313 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dcakd_mouse(display_long)|uniprotkb:Dcakd(gene name)|psi-mi:Dcakd(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080827.2|refseq:XP_006534101.1|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR027417|ensembl:ENSMUSG00000020935(gene)|ensembl:ENSMUST00000021313(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0015937"(coenzyme A biosynthetic process) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FnZw0EAGz5CmiVwGbgncUckVatc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BGZ2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988418|uniprotkb:Q3UVC2|uniprotkb:Q80U50|uniprotkb:Q8BGN7|ensembl:ENSMUSP00000102657 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:f168a_mouse(display_long)|uniprotkb:Fam168a(gene name)|psi-mi:Fam168a(display_short)|uniprotkb:Kiaa0280(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_848879.1|refseq:XP_006507982.1|refseq:XP_006507983.1|ensembl:ENSMUSG00000029461(gene)|ensembl:ENSMUST00000107042(transcript)|go:"GO:1905053"(positive regulation of base-excision repair)|interpro:IPR029247|refseq:XP_006507985.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:liVCX+41N/tqtJG1rJ7+9zKT1+A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9EPA7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988316|uniprotkb:Q6B504|ensembl:ENSMUSP00000030845|ensembl:ENSMUSP00000101318 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nmna1_mouse(display_long)|uniprotkb:Nicotinamide mononucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nmnat1(gene name)|psi-mi:Nmnat1(display_short)|uniprotkb:D4Cole1e(gene name synonym)|uniprotkb:Nmnat(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_597679.1|refseq:XP_006539168.1|ensembl:ENSMUSG00000028992(gene)|ensembl:ENSMUST00000030845(transcript)|ensembl:ENSMUST00000105693(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-MMU-196807|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1901215"(negative regulation of neuron death) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:yxzNs68kLVfCHDUyQITAc8V7TuI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TW27 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988437|ensembl:ENSMUSP00000016397 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tw27_mouse(display_long)|uniprotkb:Nelfcd(gene name)|psi-mi:Nelfcd(display_short)|uniprotkb:Th1l(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000016253(gene)|ensembl:ENSMUST00000016397(transcript)|go:"GO:0032021"(NELF complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR006942(TH1 protein) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AUNFkfXM7aMAK4zCJNVasEy1Ohs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QYI3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988177|uniprotkb:Q3TKR1|uniprotkb:Q6VVW6|uniprotkb:Q8BPG3|uniprotkb:Q8CIL2|uniprotkb:Q9CT29|uniprotkb:Q9D026|ensembl:ENSMUSP00000014339 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dnjc7_mouse(display_long)|uniprotkb:Dnajc7(gene name)|psi-mi:Dnajc7(display_short)|uniprotkb:Ttc2(gene name synonym)|uniprotkb:Cytoplasmic CAR retention protein(gene name synonym)|uniprotkb:MDj11(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062769.2|ensembl:ENSMUSG00000014195(gene)|ensembl:ENSMUST00000014339(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|mint:Q9QYI3|reactome:R-MMU-3371453 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:kWcqbxt+B+Mc5hILKCqASCcpPnQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D6X6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988469|uniprotkb:Q544M8|uniprotkb:Q8VEG1|ensembl:ENSMUSP00000045191|ensembl:ENSMUSP00000147183 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prs23_mouse(display_long)|uniprotkb:Prss23(gene name)|psi-mi:Prss23(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_083890.2|refseq:XP_006508367.1|refseq:XP_006508368.1|ensembl:ENSMUSG00000039405(gene)|ensembl:ENSMUST00000041761(transcript)|ensembl:ENSMUST00000207932(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR043504|reactome:R-MMU-381426|reactome:R-MMU-8957275 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+flD44OO5NKkm5f+6J/euhoKJbQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QZ06 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-74272|uniprotkb:Q543N1|uniprotkb:Q9D5P5|ensembl:ENSMUSP00000001950 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tolip_mouse(display_long)|uniprotkb:Tollip(gene name)|psi-mi:Tollip(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_076253.1|ensembl:ENSMUSG00000025139(gene)|ensembl:ENSMUST00000001950(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|mint:Q9QZ06|reactome:R-MMU-6798695|reactome:R-MMU-9020702 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:l31YAZvuxJMK48wHqwvgPu8lVUs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3U5K8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988080 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3u5k8_mouse(display_long)|uniprotkb:Ifit1(gene name)|psi-mi:Ifit1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:iSYNgVwA3Mg+ZCziDKmCLa56fRY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3THW5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986437|ensembl:ENSMUSP00000105359|uniprotkb:Q5NC92|uniprotkb:Q6ZWU0 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h2av_mouse(display_long)|uniprotkb:H2az2(gene name)|psi-mi:H2az2(display_short)|uniprotkb:H2A.F/Z(gene name synonym)|uniprotkb:H2A.Z variant histone 2(gene name synonym)|uniprotkb:H2afv(gene name synonym)|uniprotkb:H2av(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-606279|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|ensembl:ENSMUSG00000041126(gene)|ensembl:ENSMUST00000109737(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002119(Histone H2A)|refseq:NP_084214.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HWEdsnxjwV2Z0BAbsziMwaE/gXE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P83940 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2323027|uniprotkb:Q63182|ensembl:ENSMUSP00000111009|ensembl:ENSMUSP00000139675|ensembl:ENSMUSP00000140422|ensembl:ENSMUSP00000140962 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:eloc_mouse(display_long)|uniprotkb:Eloc(gene name)|psi-mi:Eloc(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:Stromal membrane-associated protein SMAP1B homolog(gene name synonym)|uniprotkb:Tceb1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080732.1|refseq:NP_001297399.1|refseq:XP_006495624.1|refseq:XP_006495625.1|refseq:XP_006495626.1|refseq:XP_006495627.1|dip:DIP-42814N|ensembl:ENSMUSG00000079658(gene)|ensembl:ENSMUST00000115352(transcript)|ensembl:ENSMUST00000185771(transcript)|ensembl:ENSMUST00000186948(transcript)|ensembl:ENSMUST00000188641(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030891"(VCB complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:P83940|rcsb pdb:2FNJ|rcsb pdb:2JZ3|rcsb pdb:4JGH|reactome:R-MMU-112382|reactome:R-MMU-1234176|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|reactome:R-MMU-8951664|reactome:R-MMU-9705462|reactome:R-MMU-983168 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CX48 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986548|ensembl:ENSMUSP00000018383 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:zch10_mouse(display_long)|uniprotkb:Zcchc10(gene name)|psi-mi:Zcchc10(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000018239(gene)|ensembl:ENSMUST00000018383(transcript)|refseq:NP_080755.2|go:"GO:0008270"(zinc ion binding)|interpro:IPR036875|interpro:IPR039715|go:"GO:0003676"(nucleic acid binding) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:3JZ8FHFz07zzSO+EHzHns/1yYE410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6R0H7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986270|ensembl:ENSMUSP00000140174|ensembl:ENSMUSP00000079341|uniprotkb:A2A607|uniprotkb:A2A608|uniprotkb:Q6R0H4|uniprotkb:Q6R0H5|uniprotkb:Q6R2J5|uniprotkb:Q9JJX0|uniprotkb:Q9Z1N8 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gnas1_mouse(display_long)|uniprotkb:Gnas(gene name)|psi-mi:Gnas(display_short)|uniprotkb:Gnas1(gene name synonym)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:Extra large alphas protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000027523(gene)|ensembl:ENSMUST00000080493(transcript)|ensembl:ENSMUST00000185956(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001726"(ruffle)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030142"(COPI-coated Golgi to ER transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042493"|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043588"(skin development)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050890"(cognition)|go:"GO:0051216"(cartilage development)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071107"(response to parathyroid hormone)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071514"(genomic imprinting)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000828"(regulation of parathyroid hormone secretion)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-MMU-381676|reactome:R-MMU-392851|reactome:R-MMU-418555|reactome:R-MMU-420092|reactome:R-MMU-432040|refseq:NP_001070975.1|refseq:NP_034439.2|refseq:NP_963911.1|refseq:NP_001297014.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:A34spdRKyzP3TB8XybliiA107DE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CX13 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986483|ensembl:ENSMUSP00000115772|uniprotkb:Q3TNM6 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cnih4_mouse(display_long)|uniprotkb:Cnih4(gene name)|psi-mi:Cnih4(display_short)|uniprotkb:Cornichon family AMPA receptor auxiliary protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000062169(gene)|ensembl:ENSMUST00000134115(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031730"(CCR5 chemokine receptor binding)|interpro:IPR003377(Cornichon)|refseq:NP_084407.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1NuOw99NU+vqzvB2ShuGxmE7AlY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P68134 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P43277 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-299625|ensembl:ENSMUSP00000044395|uniprotkb:Q8C6M4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h13_mouse(display_long)|uniprotkb:H1-3(gene name)|psi-mi:H1-3(display_short)|uniprotkb:H1 VAR.4(gene name synonym)|uniprotkb:H1d(gene name synonym)|uniprotkb:H1f3(gene name synonym)|uniprotkb:Hist1h1d(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000052565(gene)|ensembl:ENSMUST00000045301(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43277|reactome:R-MMU-140342|go:"GO:0000786"(nucleosome)|reactome:R-MMU-2559584|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016584"(nucleosome positioning)|refseq:NP_663759.3 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:az/dCjeaJAf5G/5QRQeFE9Q63Ps10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BG17 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986256|uniprotkb:Q91VI1|ensembl:ENSMUSP00000116103 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nol12_mouse(display_long)|uniprotkb:Nol12(gene name)|psi-mi:Nol12(display_short)|uniprotkb:Nop25(gene name synonym)|uniprotkb:Nucleolar protein of 25 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598561.2|ensembl:ENSMUSG00000033099(gene)|ensembl:ENSMUST00000138880(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR019186 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8IZocLsxZjPlXHS52JhtELQoAhM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CY46 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986377|ensembl:ENSMUSP00000034311 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q9cy46_mouse(display_long)|uniprotkb:Lsm4(gene name)|psi-mi:Lsm4(display_short)|uniprotkb:LSM4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000031848(gene)|ensembl:ENSMUST00000034311(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0042731"(PH domain binding)|go:"GO:0043005"(neuron projection)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|refseq:NP_056631.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+jfJqvwU8L0spThoP9X+mR7KxS010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O54825 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4284563|uniprotkb:Q3THF4|uniprotkb:Q3UPY9|uniprotkb:Q8VD68|ensembl:ENSMUSP00000024783 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:byst_mouse(display_long)|uniprotkb:Bysl(gene name)|psi-mi:Bysl(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_058555.3|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007955(Bystin)|reactome:R-MMU-6791226|ensembl:ENSMUSG00000023988(gene)|ensembl:ENSMUST00000024783(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001825"(blastocyst formation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:JlkD0p3MBqstE6KH1Uicqai7Lo010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P01942 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-494191 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hba_mouse(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:Hba(gene name)|psi-mi:Hba(display_short)|uniprotkb:Hba-a1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 dip:DIP-34118N|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:3HRW|reactome:R-MMU-1237044|reactome:R-MMU-1247673|reactome:R-MMU-2168880|reactome:R-MMU-9707564|reactome:R-MMU-9707616|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0009617"(response to bacterium)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|mint:P01942 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PbMJ6ngi/QKo4CGt7XQMqTFT6RU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BFU2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986394|ensembl:ENSMUSP00000104445 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h2a3_mouse(display_long)|uniprotkb:H2aw(gene name)|psi-mi:H2aw(display_short)|uniprotkb:Hist3h2a(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000078851(gene)|ensembl:ENSMUST00000108817(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-MMU-3214815|reactome:R-MMU-3214858|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5689901|refseq:NP_835736.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8QZS5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986415|ensembl:ENSMUSP00000078389|ensembl:ENSMUSP00000103078|ensembl:ENSMUSP00000103079|uniprotkb:B7ZCH3|uniprotkb:Q5NBV8 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rn183_mouse(display_long)|uniprotkb:Rnf183(gene name)|psi-mi:Rnf183(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000063851(gene)|ensembl:ENSMUST00000079420(transcript)|ensembl:ENSMUST00000107454(transcript)|ensembl:ENSMUST00000107455(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_705724.1|refseq:XP_006538402.1|ensembl:ENSMUSG00000063851 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:60K/zgdUol6bTalXu3QhPwr0D1810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99K85 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2310082|ensembl:ENSMUSP00000025542 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:serc_mouse(display_long)|uniprotkb:Psat1(gene name)|psi-mi:Psat1(display_short)|uniprotkb:Psa(gene name synonym)|uniprotkb:Psat(gene name synonym)|uniprotkb:Phosphohydroxythreonine aminotransferase(gene name synonym)|uniprotkb:Endometrial progesterone-induced protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_803155.1|ensembl:ENSMUSG00000024640(gene)|ensembl:ENSMUST00000025542(transcript)|go:"GO:0004648"("O-phospho-L-serine:2-oxoglutarate aminotransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022278|mint:Q99K85|reactome:R-MMU-977347 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:9ZAgIcJixhbde5eqfBxSg5VMXnI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3V009 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986460|ensembl:ENSMUSP00000034698|uniprotkb:Q3TUX8|uniprotkb:Q61073|uniprotkb:Q91YK3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tmed1_mouse(display_long)|uniprotkb:Tmed1(gene name)|psi-mi:Tmed1(display_short)|uniprotkb:Il1rl1l(gene name synonym)|uniprotkb:Interleukin-1 receptor-like 1 ligand(gene name synonym)|uniprotkb:Putative T1/ST2 receptor-binding protein(gene name synonym)|uniprotkb:p24 family protein gamma-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|go:"GO:0005794"(Golgi apparatus)|ensembl:ENSMUSG00000032180(gene)|ensembl:ENSMUST00000034698(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|refseq:NP_034874.2|refseq:NP_001311439.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ZlgwRPCTGQ4M0J3RJ9Tr+RDAKBk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P61211 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986346|ensembl:ENSMUSP00000111942|uniprotkb:P41276 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arl1_mouse(display_long)|uniprotkb:Arl1(gene name)|psi-mi:Arl1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6811440|ensembl:ENSMUSG00000060904(gene)|ensembl:ENSMUST00000116234(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_080135.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qC7ZdwTn0xQl0jsQIk/dBPDBn2Q10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UBX0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2366300|uniprotkb:Q8R006|ensembl:ENSMUSP00000039529 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tm109_mouse(display_long)|uniprotkb:Tmem109(gene name)|psi-mi:Tmem109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598903.1|refseq:XP_006527380.1|ensembl:ENSMUSG00000034659(gene)|ensembl:ENSMUST00000038128(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR039492|mint:Q3UBX0 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:A1j0QAd+iFKHsQUAGSp63nR++ik10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P04104 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-646772|uniprotkb:Q149E0|uniprotkb:Q9D2K8|ensembl:ENSMUSP00000023790 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:k2c1_mouse(display_long)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)|uniprotkb:Krt1(gene name)|psi-mi:Krt1(display_short)|uniprotkb:Krt2-1(gene name synonym)|uniprotkb:Keratin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032499.2|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04104|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|interpro:IPR003054(Type II keratin)|ensembl:ENSMUSG00000046834(gene)|ensembl:ENSMUST00000023790(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045095"(keratin filament)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:STENVj6SpzelAzNtQzl9kalt7cs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P49717 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-457170|uniprotkb:O89056|ensembl:ENSMUSP00000023353 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mcm4_mouse(display_long)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym)|uniprotkb:Mcm4(gene name)|psi-mi:Mcm4(display_short)|uniprotkb:Cdc21(gene name synonym)|uniprotkb:Mcmd4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032591.3|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSMUSG00000022673(gene)|ensembl:ENSMUST00000023353(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49717|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FATc9voJryESgBntkWAGwt99XyE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:E9PVX6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2553009|ensembl:ENSMUSP00000033310|intact:EBI-8357214|intact:MINT-4109797|uniprotkb:Q61769|uniprotkb:Q7TSF6 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ki67_mouse(display_long)|uniprotkb:Mki67(gene name)|psi-mi:Mki67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:E9PVX6|ensembl:ENSMUSG00000031004(gene)|ensembl:ENSMUST00000033310(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1990705"(cholangiocyte proliferation)|refseq:NP_001074586.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:gooKnaoRimWdJjijmDZsZd3WaPw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q64008 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986497|uniprotkb:Q8BHJ0|uniprotkb:Q99P59|uniprotkb:Q99P90 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rab34_mouse(display_long)|uniprotkb:Rab34(gene name)|psi-mi:Rab34(display_short)|uniprotkb:Rab39(gene name synonym)|uniprotkb:Rah(gene name synonym)|uniprotkb:Rah1(gene name synonym)|uniprotkb:Ras-related homolog(gene name synonym)|uniprotkb:Ras-related protein Rab-39(gene name synonym)|uniprotkb:Ras-related protein Rah(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 reactome:R-MMU-8873719|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030030"(cell projection organization)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032418"(lysosome localization)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0005770"(late endosome)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1905171"(positive regulation of protein localization to phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|refseq:NP_001152954.1|refseq:NP_258436.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BBB9N/zuCY5aiJ1YDRDJLFB8mgQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DCF9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986530|ensembl:ENSMUSP00000029414|uniprotkb:Q8C0Z8 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ssrg_mouse(display_long)|uniprotkb:Ssr3(gene name)|psi-mi:Ssr3(display_short)|uniprotkb:Signal sequence receptor subunit gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000027828(gene)|ensembl:ENSMUST00000029414(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009779(Translocon-associated, gamma subunit)|refseq:NP_080431.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:wyWQAOAJFKJO0Gs7g2inNFK74PA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R1P4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-991653|ensembl:ENSMUSP00000033008 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psa1_mouse(display_long)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:Psma1(gene name)|psi-mi:Psma1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:Q9R1P4|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|go:"GO:0005829"(cytosol)|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000030751(gene)|ensembl:ENSMUST00000033008(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002376"(immune system process)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|refseq:NP_036095.1|dip:DIP-35147N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5AV1kxiJdOzf5jh1YRmUL94hQwk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91Z83 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-299920|ensembl:ENSMUSP00000099867|ensembl:ENSMUSP00000126840|uniprotkb:Q3TGM2|uniprotkb:Q3TZN2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:myh7_mouse(display_long)|uniprotkb:Myh7(gene name)|psi-mi:Myh7(display_short)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000053093(gene)|ensembl:ENSMUST00000102803(transcript)|ensembl:ENSMUST00000168485(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q91Z83|refseq:NP_542766.1|refseq:XP_017171330.1|refseq:XP_017171331.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:bU/7TlAhyFe1cU0W5ljnnrelgMs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BV79 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986559|uniprotkb:Q5RJH5|uniprotkb:Q6ZQD5|ensembl:ENSMUSP00000077697 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:trnk1_mouse(display_long)|uniprotkb:Trank1(gene name)|psi-mi:Trank1(display_short)|uniprotkb:Gm187(gene name synonym)|uniprotkb:Kiaa0342(gene name synonym)|uniprotkb:Lba1(gene name synonym)|uniprotkb:Lupus brain antigen 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001158131.1|ensembl:ENSMUSG00000062296(gene)|ensembl:ENSMUST00000078626(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR027417|interpro:IPR036770|interpro:IPR039904 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:573bZSLjfNnRP1kEL0pHN49Bc+s10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z1B5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2552918|ensembl:ENSMUSP00000098897|ensembl:ENSMUSP00000112304|uniprotkb:Q9JI53 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:md2l1_mouse(display_long)|uniprotkb:Mad2l1(gene name)|psi-mi:Mad2l1(display_short)|uniprotkb:Mad2a(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062372.2|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-2467813|ensembl:ENSMUSG00000029910(gene)|ensembl:ENSMUST00000101343(transcript)|ensembl:ENSMUST00000116605(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q9Z1B5|reactome:R-MMU-141405|reactome:R-MMU-141430|reactome:R-MMU-141444|reactome:R-MMU-174184|reactome:R-MMU-176409|reactome:R-MMU-179409|refseq:XP_006506469.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:T2SuApPGRno6LWCTPwVqAvQEVZQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D6L8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986583|ensembl:ENSMUSP00000080378|ensembl:ENSMUSP00000109988|ensembl:ENSMUSP00000112947|uniprotkb:Q812D2|uniprotkb:Q9CY23 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ppil3_mouse(display_long)|uniprotkb:Ppil3(gene name)|psi-mi:Ppil3(display_short)|uniprotkb:Cyp10l(gene name synonym)|uniprotkb:CYP10L(gene name synonym)|uniprotkb:Cyclophilin-like protein PPIL3(gene name synonym)|uniprotkb:Rotamase PPIL3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000026035(gene)|ensembl:ENSMUST00000081677(transcript)|ensembl:ENSMUST00000114348(transcript)|ensembl:ENSMUST00000117069(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0008380"(RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|interpro:IPR044666|reactome:R-MMU-72163|refseq:NP_001272755.1|refseq:NP_001272756.1|refseq:NP_081627.1|refseq:NP_081650.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:9xKfu1r5Cy9wy9HpgWZcJiXm4vc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62192 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-357610|uniprotkb:P49014|uniprotkb:Q96AZ3|uniprotkb:Q03527|ensembl:ENSMUSP00000021595 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prs4_mouse(display_long)|uniprotkb:Psmc1(gene name)|psi-mi:Psmc1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000021178(gene)|ensembl:ENSMUST00000021595(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62192|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|refseq:NP_032973.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P60843 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6665935|ensembl:ENSMUSP00000127034|uniprotkb:P04765|uniprotkb:Q61516 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:if4a1_mouse(display_long)|uniprotkb:Eif4a1(gene name)|psi-mi:Eif4a1(display_short)|uniprotkb:Ddx2a(gene name synonym)|uniprotkb:Eif4a(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000059796(gene)|ensembl:ENSMUST00000163666(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60843|rcsb pdb:6XKI|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:NP_659207.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O35130 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989709|ensembl:ENSMUSP00000004379 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nep1_mouse(display_long)|uniprotkb:Emg1(gene name)|psi-mi:Emg1(display_short)|uniprotkb:C2f(gene name synonym)|uniprotkb:Grcc2f(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1248)-N1)-methyltransferase"(gene name synonym)|uniprotkb:18S rRNA Psi1248 methyltransferase(gene name synonym)|uniprotkb:Nucleolar protein EMG1 homolog(gene name synonym)|uniprotkb:Protein C2f(gene name synonym)|uniprotkb:Ribosome biogenesis protein NEP1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_038564.1|go:"GO:0017126"(nucleologenesis)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|interpro:IPR029026|interpro:IPR029028|reactome:R-MMU-6791226|ensembl:ENSMUSG00000004268(gene)|ensembl:ENSMUST00000004379(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vNt3J3tZX0uMtBf9qMe8OXyQZSE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91VC3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2552399|ensembl:ENSMUSP00000026667|uniprotkb:Q3UD29|uniprotkb:Q3TEZ8|uniprotkb:B2RY38|uniprotkb:Q8BVY3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:if4a3_mouse(display_long)|uniprotkb:Eif4a3(gene name)|psi-mi:Eif4a3(display_short)|uniprotkb:Ddx48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 reactome:R-MMU-975957|ensembl:ENSMUSG00000025580(gene)|ensembl:ENSMUST00000026667(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|refseq:NP_619610.1|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q91VC3|reactome:R-MMU-1169408|reactome:R-MMU-159236|reactome:R-MMU-429947|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6jjMHbLWWbe2j3Qv+g8b/PbY7Ps10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99LE6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989732|uniprotkb:Q3UA24|uniprotkb:Q8C1S5|uniprotkb:Q9JL48|ensembl:ENSMUSP00000030795 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:abcf2_mouse(display_long)|uniprotkb:Abcf2(gene name)|psi-mi:Abcf2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001177372.1|refseq:NP_038881.1|refseq:XP_006535789.1|refseq:XP_006535790.1|ensembl:ENSMUSG00000028953(gene)|ensembl:ENSMUST00000030795(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:++h2s7Eilydt9CGZHgsp7lU38Ys10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VDP2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989795|uniprotkb:A2A3V4|uniprotkb:Q3URC0|uniprotkb:Q8C8Z1|uniprotkb:Q9CWC1|ensembl:ENSMUSP00000040134|ensembl:ENSMUSP00000110903 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:steep_mouse(display_long)|uniprotkb:Steep1(gene name)|psi-mi:Steep1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_084227.1|ensembl:ENSMUSG00000006423(gene)|ensembl:ENSMUST00000047486(transcript)|ensembl:ENSMUST00000115248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0044297"(cell body)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR029704 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:cTtZTKsgAWLF3OyCvz6sdtFotJI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922Q2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989629|uniprotkb:Q3U7D5|uniprotkb:Q99LZ1|uniprotkb:Q9CU84|uniprotkb:Q9CXN9|ensembl:ENSMUSP00000021866 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:riok1_mouse(display_long)|uniprotkb:Riok1(gene name)|psi-mi:Riok1(display_short)|uniprotkb:RIO kinase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_077204.2|ensembl:ENSMUSG00000021428(gene)|ensembl:ENSMUST00000021866(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034708"(methyltransferase complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935|reactome:R-MMU-6791226|go:"GO:0016787"(hydrolase activity) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Y2YtWqBTATvtofQ7V7t5xeH2wmA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:B2RQC6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3043834|ensembl:ENSMUSP00000013773|uniprotkb:B7ZN27 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pyr1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000013629(gene)|ensembl:ENSMUST00000013773(transcript)|go:"GO:0002134"(UTP binding)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0001889"(liver development)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|go:"GO:0019899"(enzyme binding)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:B2RQC6|reactome:R-MMU-500753|refseq:NP_076014.1|refseq:NP_001276451.1|dip:DIP-61412N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:t+qQw7me78vEm/Y4VBBhS8fmCsY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3THE2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-770040|uniprotkb:Q3TVH2|uniprotkb:Q9CQL8|ensembl:ENSMUSP00000042364|ensembl:ENSMUSP00000156763|ensembl:ENSMUSP00000156883 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ml12b_mouse(display_long)|uniprotkb:Mrlc2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:Myl12b(gene name)|psi-mi:Myl12b(display_short)|uniprotkb:Mylc2b(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_075891.1|dip:DIP-31955N|ensembl:ENSMUSG00000034868(gene)|ensembl:ENSMUSG00000117098(gene)|ensembl:ENSMUST00000038446(transcript)|ensembl:ENSMUST00000233004(transcript)|ensembl:ENSMUST00000233357(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:Q3THE2|reactome:R-MMU-445355|reactome:R-MMU-5627123 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62334 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-357694|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q3TKK1|uniprotkb:Q810A6|uniprotkb:Q9CXH9|ensembl:ENSMUSP00000022380 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prs10_mouse(display_long)|uniprotkb:Psmc6(gene name)|psi-mi:Psmc6(display_short)|uniprotkb:Sug2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080235.2|ensembl:ENSMUSG00000021832(gene)|ensembl:ENSMUST00000022380(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0090261"(positive regulation of inclusion body assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62334|reactome:R-MMU-1169091|go:"GO:0031597"(cytosolic proteasome complex)|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QE8jzSEp1bpzhOi/oAAnV18QK2410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D3N8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989514|uniprotkb:Q8BUR0|uniprotkb:Q8VI03|uniprotkb:Q9D3Q5|uniprotkb:Q9D8L8|ensembl:ENSMUSP00000130324 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:grtp1_mouse(display_long)|uniprotkb:Grtp1(gene name)|psi-mi:Grtp1(display_short)|uniprotkb:Tbc1d6(gene name synonym)|uniprotkb:TBC1 domain family member 6(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080044.2|refseq:XP_006508914.1|refseq:XP_017168426.1|ensembl:ENSMUSG00000038515(gene)|ensembl:ENSMUST00000165605(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:x+BKntdOoNclB/GbBach0As0yig10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P13864 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-301927|uniprotkb:Q80ZU3|uniprotkb:Q9CSC6|uniprotkb:P97413|uniprotkb:Q9QXX6|ensembl:ENSMUSP00000004202 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dnmt1_mouse(display_long)|uniprotkb:Dnmt1(gene name)|psi-mi:Dnmt1(display_short)|uniprotkb:Dnmt(gene name synonym)|uniprotkb:Met1(gene name synonym)|uniprotkb:Uim(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase MmuI(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001186360.2|refseq:NP_001186361.1|refseq:NP_001186362.1|refseq:NP_034196.5|interpro:IPR031303|interpro:IPR043151|mint:P13864|rcsb pdb:3AV4|rcsb pdb:3AV5|rcsb pdb:3AV6|rcsb pdb:3PT6|rcsb pdb:3PT9|rcsb pdb:4DA4|rcsb pdb:5GUT|rcsb pdb:5GUV|rcsb pdb:5WY1|rcsb pdb:6W8V|rcsb pdb:6W8W|reactome:R-MMU-212300|reactome:R-MMU-4655427|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|ensembl:ENSMUST00000004202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0044026"(DNA hypermethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051718"("DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates")|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:0016458"(obsolete gene silencing)|ensembl:ENSMUSG00000004099(gene)|refseq:NP_001300940.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:JgHTnDhDn4nuU6ww3jXfDPq01xY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C0C7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4286479|uniprotkb:Q3U3Q9|uniprotkb:Q91WR4|uniprotkb:Q922S1|ensembl:ENSMUSP00000003906 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:syfa_mouse(display_long)|uniprotkb:Farsa(gene name)|psi-mi:Farsa(display_short)|uniprotkb:Farsla(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079924.2|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|ensembl:ENSMUSG00000003808(gene)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|ensembl:ENSMUST00000003906(transcript)|go:"GO:0000049"(tRNA binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q8C0C7 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BSyxrw9ab0HyAuktFxcgvTKUOKE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6PHN9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1373353|ensembl:ENSMUSP00000031492 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rab35_mouse(display_long)|uniprotkb:Rab35(gene name)|psi-mi:Rab35(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_937806.1|dip:DIP-38238N|ensembl:ENSMUSG00000029518(gene)|ensembl:ENSMUST00000031492(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q6PHN9|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P14206 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQV8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-771608|uniprotkb:O70455|uniprotkb:Q3TY33|uniprotkb:Q3UAN6|ensembl:ENSMUSP00000018470 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:1433b_mouse(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_061223.2|refseq:XP_006499972.1|reactome:R-MMU-111447|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-170968|reactome:R-MMU-2028269|reactome:R-MMU-392517|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-75035|reactome:R-MMU-9614399|ensembl:ENSMUSG00000018326(gene)|ensembl:ENSMUST00000018470(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:4GNT|rcsb pdb:5F74|rcsb pdb:5WFU|rcsb pdb:5WFX - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:g94luGOxfq+Jbi0ztZ7gbAkp+2A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P05213 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99K43 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-644779|uniprotkb:E9QPF0|uniprotkb:Q8CE25|ensembl:ENSMUSP00000043379 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prc1_mouse(display_long)|uniprotkb:Prc1(gene name)|psi-mi:Prc1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001272926.1|reactome:R-MMU-5625900|interpro:IPR032921|ensembl:ENSMUSG00000038943(gene)|ensembl:ENSMUST00000047558(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0070938"(contractile ring)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR007145(MAP65/ASE1) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Xu052dxwVt00LivzQdjuZFKxtEc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C7Q4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989532|uniprotkb:O08752|uniprotkb:Q8BN66|ensembl:ENSMUSP00000137174|ensembl:ENSMUSP00000137345 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rbm4_mouse(display_long)|uniprotkb:Rbm4(gene name)|psi-mi:Rbm4(display_short)|uniprotkb:Rbm4a(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001277051.1|refseq:NP_001277052.1|refseq:NP_001277053.1|refseq:NP_001277054.1|refseq:NP_033058.2|ensembl:ENSMUSG00000094936(gene)|ensembl:ENSMUST00000179189(transcript)|ensembl:ENSMUST00000180248(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:JieuX1WaD4o6zdcEoobXK37voqY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CIG8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2527009|uniprotkb:Q3TNN1|uniprotkb:Q9QZS9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:anm5_mouse(display_long)|uniprotkb:Prmt5(gene name)|psi-mi:Prmt5(display_short)|uniprotkb:Jbp1(gene name synonym)|uniprotkb:Skb1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR035075|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|reactome:R-MMU-191859|reactome:R-MMU-3214858|reactome:R-MMU-6804760|refseq:NP_038796.2|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR029063|refseq:NP_001300835.1|refseq:NP_001300836.1|interpro:IPR025799|interpro:IPR035247|interpro:IPR035248|mint:Q8CIG8 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:xMQdLXo5TNQQFK9XjxjH+5/ZwNA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q923D4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6260940|ensembl:ENSMUSP00000100771 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sf3b5_mouse(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:Sf3b10(gene name synonym)|uniprotkb:Sf3b5(gene name)|psi-mi:Sf3b5(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000078348(gene)|ensembl:ENSMUST00000105139(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q923D4|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_780311.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:mqP6Bh/N2HYfOkVjIAM9nu17Qro10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q70IV5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989763|uniprotkb:Q3UPZ4|uniprotkb:Q6A081|uniprotkb:Q70IV3|uniprotkb:Q70IV4|ensembl:ENSMUSP00000073855 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:synem_mouse(display_long)|uniprotkb:Synm(gene name)|psi-mi:Synm(display_short)|uniprotkb:Dmn(gene name synonym)|uniprotkb:Kiaa0353(gene name synonym)|uniprotkb:Desmuslin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_899135.3|refseq:NP_964001.2|refseq:NP_997546.2|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030018"(Z disc)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031443"(fast-twitch skeletal muscle fiber contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0060053"(neurofilament cytoskeleton)|interpro:IPR018039|interpro:IPR030634|interpro:IPR039008|go:"GO:0005200"(structural constituent of cytoskeleton)|ensembl:ENSMUSG00000030554(gene)|ensembl:ENSMUST00000074233(transcript) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Fgh1JpG9IDFBh3r1Sorb6NU+60c10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CY57 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6393116|ensembl:ENSMUSP00000061800|uniprotkb:Q8C5N4|uniprotkb:Q9D7T3|uniprotkb:Q9DB03|uniprotkb:Q9DC54|uniprotkb:Q9JJ95|uniprotkb:Q0VBG3|uniprotkb:Q3U7V6|uniprotkb:Q3UF43|uniprotkb:Q3V105|uniprotkb:Q5XJG9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:chtop_mouse(display_long)|uniprotkb:Chtop(gene name)|psi-mi:Chtop(display_short)|uniprotkb:Fop(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym)|uniprotkb:MNCb-1706(orf name) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000001017(gene)|ensembl:ENSMUST00000049937(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR025715|mint:Q9CY57|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856|refseq:NP_075704.2|refseq:NP_001280705.1|refseq:NP_001280706.1|refseq:NP_001280707.1|refseq:NP_001280708.1|refseq:NP_001280710.1|refseq:NP_001280711.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:tbiD3N+cZ5sPCgf8oao5CrHEwtE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q0GNC1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6908712|uniprotkb:Q14C56|uniprotkb:Q499F7|uniprotkb:Q6P9T3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:inf2_mouse(display_long)|uniprotkb:Inf2(gene name)|psi-mi:Inf2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0003779"(actin binding)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR042201|go:"GO:0031267"(small GTPase binding)|go:"GO:0032535"(regulation of cellular component size)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027649|refseq:NP_940803.2|dip:DIP-61548N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:aggZuhV3g76aRx4oCN3VSUPJVFM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P63154 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989586|uniprotkb:Q542E8|uniprotkb:Q9CQC1|ensembl:ENSMUSP00000001818 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:crnl1_mouse(display_long)|uniprotkb:Crnkl1(gene name)|psi-mi:Crnkl1(display_short)|uniprotkb:Crooked neck homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080096.1|ensembl:ENSMUSG00000001767(gene)|ensembl:ENSMUST00000001818(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-MMU-72163 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:9DgysHExtqmhzmps9wzWd8iF9wo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CVC4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989604 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q9cvc4_mouse(display_long)|uniprotkb:Misp3(gene name)|psi-mi:Misp3(display_short)|uniprotkb:2210011C24Rik(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR029304|refseq:NP_001278221.1|interpro:IPR042779 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ttOA2pZF3mMZqY1UVjaFxqAl5JU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91YN9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BMU5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989753 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q8bmu5_mouse(display_long)|uniprotkb:Tusc3(gene name)|psi-mi:Tusc3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR021149|go:"GO:0006486"(protein glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR036249 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FCgcEb4GlTniyuXzmWszrFEU4bU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P15116 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-397974|uniprotkb:Q64260|uniprotkb:Q6GU11|intact:EBI-2255565|ensembl:ENSMUSP00000025166 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cadh2_mouse(display_long)|uniprotkb:Cdh2(gene name)|psi-mi:Cdh2(display_short)|uniprotkb:Neural cadherin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_031690.3|ensembl:ENSMUSG00000024304(gene)|ensembl:ENSMUST00000025166(transcript)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030315"(T-tubule)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P15116|rcsb pdb:1NCG|rcsb pdb:1NCH|rcsb pdb:1NCI|rcsb pdb:1NCJ|rcsb pdb:1OP4|rcsb pdb:2QVI|rcsb pdb:3Q2W|rcsb pdb:4NUM|rcsb pdb:4NUP|rcsb pdb:4NUQ|reactome:R-MMU-381426|reactome:R-MMU-418990|reactome:R-MMU-525793|reactome:R-MMU-8957275|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|dip:DIP-31564N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Yon1udPwyvjKP2+GVGUcrsZtFng10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P61027 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-911581|uniprotkb:O88386|uniprotkb:Q9D7X6|ensembl:ENSMUSP00000021001 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rab10_mouse(display_long)|uniprotkb:Rab10(gene name)|psi-mi:Rab10(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_057885.1|dip:DIP-37720N|ensembl:ENSMUSG00000020671(gene)|ensembl:ENSMUST00000021001(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61027|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9EPL4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989610|uniprotkb:A0JG25|uniprotkb:Q3TDX0|uniprotkb:Q641L4|uniprotkb:Q8R567|uniprotkb:Q9EPL3|uniprotkb:Q9JJ88|ensembl:ENSMUSP00000033163 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:metl9_mouse(display_long)|uniprotkb:Mettl9(gene name)|psi-mi:Mettl9(display_short)|uniprotkb:drev(gene name synonym)|uniprotkb:DORA reverse strand protein(gene name synonym)|uniprotkb:MNCb-5680(orf name)|uniprotkb:Methyltransferase-like protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_067529.2|ensembl:ENSMUSG00000030876(gene)|ensembl:ENSMUST00000033163(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0032259"(methylation)|go:"GO:0106370"(protein-L-histidine N-pros-methyltransferase activity)|interpro:IPR007884(DREV methyltransferase)|interpro:IPR029063 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:GQDw7kKMmOdBKIPslXM3Iw1/mB810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62983 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4282373|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P49664|uniprotkb:P62991|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D2W3|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|ensembl:ENSMUSP00000099908|ensembl:ENSMUSP00000099909 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rs27a_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-5689901|reactome:R-MMU-5693565|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6783310|reactome:R-MMU-6791226|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804760|reactome:R-MMU-6807004|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-5689877|reactome:R-MMU-69231|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-69601|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-75815|reactome:R-MMU-8849469|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8863795|reactome:R-MMU-8866652|reactome:R-MMU-8866654|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948747|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-901032|reactome:R-MMU-9010553|reactome:R-MMU-9013507|reactome:R-MMU-9020702|reactome:R-MMU-9033241|reactome:R-MMU-912631|reactome:R-MMU-917729|reactome:R-MMU-917937|reactome:R-MMU-936440|reactome:R-MMU-936964|reactome:R-MMU-937039|reactome:R-MMU-937041|reactome:R-MMU-937042|reactome:R-MMU-8932339|reactome:R-MMU-937072|reactome:R-MMU-9645460|reactome:R-MMU-9648002|reactome:R-MMU-9664873|reactome:R-MMU-9705462|reactome:R-MMU-9706369|reactome:R-MMU-9708530|reactome:R-MMU-975144|reactome:R-MMU-975163|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-983168|reactome:R-MMU-9646399|ensembl:ENSMUSG00000020460(gene)|ensembl:ENSMUST00000102844(transcript)|ensembl:ENSMUST00000102845(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|reactome:R-MMU-110320|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1253288|reactome:R-MMU-1295596|reactome:R-MMU-1358803|reactome:R-MMU-156827|reactome:R-MMU-168638|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|reactome:R-MMU-174048|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-179409|reactome:R-MMU-1799339|reactome:R-MMU-182971|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-201681|reactome:R-MMU-202424|reactome:R-MMU-205043|interpro:IPR038582|rcsb pdb:5GVI|reactome:R-MMU-209543|rcsb pdb:5XIS|rcsb pdb:5XIT|rcsb pdb:5XIU|reactome:R-MMU-209560|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-2173788|reactome:R-MMU-2173791|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-2467813|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2565942|reactome:R-MMU-2672351|reactome:R-MMU-2871837|reactome:R-MMU-3134975|reactome:R-MMU-349425|reactome:R-MMU-3769402|reactome:R-MMU-382556|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-2122948|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-4641263|reactome:R-MMU-532668|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5675221|reactome:R-MMU-5675482|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-5685942|reactome:R-MMU-5687128|reactome:R-MMU-5689603|refseq:NP_001029037.1|refseq:NP_077239.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AkJxTgRFL5RT5jWk5i3y4zX5tfA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P63037 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CYR0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989649|ensembl:ENSMUSP00000031971 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ssbp_mouse(display_long)|uniprotkb:Ssbp1(gene name)|psi-mi:Ssbp1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_082634.1|refseq:NP_997633.1|refseq:XP_006506392.1|refseq:XP_017177153.1|ensembl:ENSMUSG00000029911(gene)|ensembl:ENSMUST00000031971(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q9CYR0 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:mPiUWKFQ/gJufRp4aggO3UUJdG810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O08614 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4285301 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:o08614_mouse(display_long)|uniprotkb:Utrn(gene name)|psi-mi:Utrn(display_short)|uniprotkb:utrophin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR000433(Zinc finger, ZZ-type)|mint:O08614|interpro:IPR036020|interpro:IPR036872|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008270"(zinc ion binding)|interpro:IPR035436|interpro:IPR043145 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:nzdkC5iTKAQUH8tJQjqpr3Tdm9o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P30999 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-529924|uniprotkb:Q3TSU9|uniprotkb:Q80XQ4|uniprotkb:Q8CHF8|ensembl:ENSMUSP00000064518|ensembl:ENSMUSP00000107320|ensembl:ENSMUSP00000141166 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ctnd1_mouse(display_long)|uniprotkb:Kiaa0384(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:Ctnnd1(gene name)|psi-mi:Ctnnd1(display_short)|uniprotkb:Catns(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001078917.1|refseq:NP_001078918.1|refseq:NP_001078919.1|refseq:NP_001078922.1|refseq:NP_031641.2|refseq:XP_006498698.1|refseq:XP_017170690.1|refseq:XP_017170697.1|dip:DIP-31972N|ensembl:ENSMUSG00000034101(gene)|ensembl:ENSMUSG00000101645(gene)|ensembl:ENSMUST00000067232(transcript)|ensembl:ENSMUST00000111691(transcript)|ensembl:ENSMUST00000189772(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001822"(kidney development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060690"(epithelial cell differentiation involved in salivary gland development)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:P30999|reactome:R-MMU-418990|reactome:R-MMU-5218920 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:CvcAbgejB5iLlsSAxt47G/6W3P410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q02053 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2310520|uniprotkb:A6H6S6|uniprotkb:P31253|uniprotkb:Q542H8|ensembl:ENSMUSP00000001989|ensembl:ENSMUSP00000086626 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:uba1_mouse(display_long)|uniprotkb:Uba1(gene name)|psi-mi:Uba1(display_short)|uniprotkb:Sbx(gene name synonym)|uniprotkb:Ube1(gene name synonym)|uniprotkb:Ube1ax(gene name synonym)|uniprotkb:Ube1x(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Ubiquitin-like modifier-activating enzyme 1 X(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1 X(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001129557.1|refseq:NP_001263245.1|refseq:NP_001263246.1|refseq:NP_033483.2|ensembl:ENSMUSG00000001924(gene)|ensembl:ENSMUST00000001989(transcript)|ensembl:ENSMUST00000089217(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030057"(desmosome)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032446"(protein modification by small protein conjugation)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:Q02053|rcsb pdb:1Z7L|rcsb pdb:2LZJ|rcsb pdb:2V31|reactome:R-MMU-8866652|reactome:R-MMU-983168|interpro:IPR019572 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:358Lm1CC2dWXeDL+IXAM2KaOlqM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CGB3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989673|uniprotkb:Q69ZG3|uniprotkb:Q7TN77|uniprotkb:Q8BJC8 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:uaca_mouse(display_long)|uniprotkb:Uaca(gene name)|psi-mi:Uaca(display_short)|uniprotkb:Kiaa1561(gene name synonym)|uniprotkb:Nuclear membrane-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR030227|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000727(Target SNARE coiled-coil region)|refseq:NP_082559.1|refseq:XP_017169098.1|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043293"(apoptosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:0009411"(response to UV)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|reactome:R-MMU-9013407|interpro:IPR036770 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:KqGCS0tg7lkDxcadqXj4i9F2+Fc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q08024 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-475586|uniprotkb:Q08025|uniprotkb:Q62050|uniprotkb:Q62051|uniprotkb:Q8C282|uniprotkb:Q8CGD5|ensembl:ENSMUSP00000059382 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pebb_mouse(display_long)|uniprotkb:Polyomavirus enhancer-binding protein 2 beta subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 subunit beta(gene name synonym)|uniprotkb:SL3/AKV core-binding factor beta subunit(gene name synonym)|uniprotkb:Cbfb(gene name)|psi-mi:Cbfb(display_short)|uniprotkb:Pebp2b(gene name synonym)|uniprotkb:Pebpb2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000031885(gene)|ensembl:ENSMUST00000052209(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR003417(Core binding factor, beta subunit)|refseq:NP_001154928.1|refseq:NP_001154929.1|refseq:NP_001154930.1|refseq:NP_071704.3|rcsb pdb:1ILF|interpro:IPR036552|rcsb pdb:1IO4|rcsb pdb:2JHB|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|reactome:R-MMU-8877330|reactome:R-MMU-8878166|reactome:R-MMU-8931987|reactome:R-MMU-8934593|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-8939243|reactome:R-MMU-8939245|reactome:R-MMU-8939246|reactome:R-MMU-8939247|reactome:R-MMU-8941326|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:rLI+FjXTPj8Z/0+MNAdcOhjHpMg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UQU0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988701|uniprotkb:Q0P669|uniprotkb:Q5FWH1|uniprotkb:Q811F7|ensembl:ENSMUSP00000152390 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:brd9_mouse(display_long)|uniprotkb:Brd9(gene name)|psi-mi:Brd9(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001019679.2|refseq:NP_001294970.1|ensembl:ENSMUST00000222399(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|ensembl:ENSMUSG00000057649(gene) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:R1E1Ng2LX7v19w+A6AUf4MWBEO810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P43274 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-913424|ensembl:ENSMUSP00000057308|uniprotkb:Q5EBH3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h14_mouse(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1 VAR.2(gene name synonym)|uniprotkb:H1e(gene name synonym)|uniprotkb:H1f4(gene name synonym)|uniprotkb:Hist1h1e(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000051627(gene)|ensembl:ENSMUST00000062045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43274|reactome:R-MMU-140342|reactome:R-MMU-2559584|refseq:NP_056602.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RbnBt0O11C8PWtfWp8tJJxsn00A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WUK4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1180276|ensembl:ENSMUSP00000023867 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rfc2_mouse(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Rfc2(gene name)|psi-mi:Rfc2(display_short)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_064406.1|ensembl:ENSMUSG00000023104(gene)|ensembl:ENSMUST00000023867(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473|reactome:R-MMU-5693607 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:2j8wh6ZmnhZRPxiT9YkzZzfQXME10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P52293 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3043908|ensembl:ENSMUSP00000018506|ensembl:ENSMUSP00000137310|uniprotkb:Q64292 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ima1_mouse(display_long)|uniprotkb:Kpna2(gene name)|psi-mi:Kpna2(display_short)|uniprotkb:Rch1(gene name synonym)|uniprotkb:Importin alpha P1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:Pendulin(gene name synonym)|uniprotkb:Pore targeting complex 58 kDa subunit(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000018362(gene)|ensembl:ENSMUSG00000066878(gene)|ensembl:ENSMUST00000018506(transcript)|ensembl:ENSMUST00000086423(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52293|rcsb pdb:1EJL|rcsb pdb:1EJY|rcsb pdb:1IAL|rcsb pdb:1IQ1|rcsb pdb:1PJM|rcsb pdb:1PJN|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1Y2A|rcsb pdb:2C1M|rcsb pdb:2YNR|rcsb pdb:3BTR|rcsb pdb:3KND|rcsb pdb:3L3Q|rcsb pdb:3OQS|rcsb pdb:3Q5U|rcsb pdb:3RZ9|rcsb pdb:3RZX|rcsb pdb:3TPM|rcsb pdb:3TPO|rcsb pdb:3UKW|rcsb pdb:3UKX|rcsb pdb:3UKZ|rcsb pdb:3UL0|rcsb pdb:3UL1|rcsb pdb:3UVU|rcsb pdb:3VE6|rcsb pdb:3ZIN|rcsb pdb:3ZIO|rcsb pdb:3ZIP|rcsb pdb:3ZIQ|rcsb pdb:3ZIR|rcsb pdb:4BA3|rcsb pdb:4HTV|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:4OIH|rcsb pdb:4U54|rcsb pdb:4U58|rcsb pdb:4U5L|rcsb pdb:4U5N|rcsb pdb:4U5O|rcsb pdb:4U5S|rcsb pdb:4U5U|rcsb pdb:4U5V|rcsb pdb:4UAF|rcsb pdb:4YI0|rcsb pdb:4ZDU|rcsb pdb:5B56|rcsb pdb:5CTT|rcsb pdb:5D5K|rcsb pdb:5E6Q|rcsb pdb:5EKF|rcsb pdb:5EKG|rcsb pdb:5FC8|rcsb pdb:5GXW|rcsb pdb:3UKY|rcsb pdb:5HHG|rcsb pdb:5HUW|rcsb pdb:5HUY|rcsb pdb:5K9S|rcsb pdb:5KLR|rcsb pdb:5SVZ|rcsb pdb:5U5P|rcsb pdb:5U5R|rcsb pdb:5UMZ|rcsb pdb:5V5O|rcsb pdb:5V5P|rcsb pdb:5W41|rcsb pdb:5W4E|rcsb pdb:5W4F|rcsb pdb:5W4G|rcsb pdb:5WUM|rcsb pdb:5WUN|rcsb pdb:5X8N|rcsb pdb:6BVT|rcsb pdb:6BW0|rcsb pdb:6BW1|rcsb pdb:6D7M|rcsb pdb:6D7N|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:5KLT|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|rcsb pdb:6MJL|rcsb pdb:6P6A|rcsb pdb:6P6E|rcsb pdb:6WX7|rcsb pdb:7JJM|rcsb pdb:7JK7|rcsb pdb:7JVO|rcsb pdb:7L04|reactome:R-MMU-5693548|refseq:NP_034785.1|dip:DIP-47774N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qML5OVHqAJODiP+FSG9fTsiV3JQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DC51 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-641852|uniprotkb:Q3TGV1|uniprotkb:Q61019|uniprotkb:A2AE36|ensembl:ENSMUSP00000000001 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gnai3_mouse(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034436.1|dip:DIP-49479N|ensembl:ENSMUSG00000000001(gene)|ensembl:ENSMUST00000000001(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q9DC51|rcsb pdb:3AB3|reactome:R-MMU-170670|reactome:R-MMU-392170|reactome:R-MMU-418594|reactome:R-MMU-9009391 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:YJ4mEQU/4IYIxCCj7qgeNh92TNc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P83917 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:W2npW/vFRcuTkStKpknsAP69q6I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P31266 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1392666|uniprotkb:Q80UN8|uniprotkb:Q8C4Z3|ensembl:ENSMUSP00000040694 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:suh_mouse(display_long)|uniprotkb:Rbpj(gene name)|psi-mi:Rbpj(display_short)|uniprotkb:Igkjrb1(gene name synonym)|uniprotkb:Igkrsbp(gene name synonym)|uniprotkb:Rbpsuh(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001074396.1|refseq:NP_033061.3|dip:DIP-171N|ensembl:ENSMUSG00000039191(gene)|ensembl:ENSMUST00000037618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:3BRG|rcsb pdb:3IAG|rcsb pdb:4J2X|rcsb pdb:5EG6|rcsb pdb:6DKS|rcsb pdb:6WQU|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6e2XZZX+zWA0UexPo1D0+3Hv08Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62196 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-357713|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:Q3UL51|uniprotkb:P52915|uniprotkb:P52916|uniprotkb:Q9CWN5|ensembl:ENSMUSP00000021049 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prs8_mouse(display_long)|uniprotkb:Psmc5(gene name)|psi-mi:Psmc5(display_short)|uniprotkb:Sug1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032976.1|ensembl:ENSMUSG00000020708(gene)|ensembl:ENSMUST00000021049(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62196|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|dip:DIP-35174N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q68ED3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988734|uniprotkb:A6H635|uniprotkb:Q8C0K6 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:papd5_mouse(display_long)|uniprotkb:PAP-associated domain-containing protein 5(gene name synonym)|uniprotkb:Papd5(gene name synonym)|uniprotkb:Terminal uridylyltransferase 3(gene name synonym)|uniprotkb:Topoisomerase-related function protein 4-2(gene name synonym)|uniprotkb:Tent4b(gene name)|psi-mi:Tent4b(display_short)|uniprotkb:"Non-canonical poly(A) RNA polymerase PAPD5"(gene name synonym)|uniprotkb:Terminal guanylyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR043519|refseq:NP_001157969.1|refseq:NP_001157970.1|refseq:NP_001157971.1|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR002058(PAP/25A-associated)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0043630"(ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070568"(guanylyltransferase activity)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR040136 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AdmYYNh4uxZv4/jniL+mls+BlmY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0N7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1236740|ensembl:ENSMUSP00000023666|ensembl:ENSMUSP00000113684 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:caf1b_mouse(display_long)|uniprotkb:Chaf1b(gene name)|psi-mi:Chaf1b(display_short)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_006522910.1|refseq:NP_082359.1|ensembl:ENSMUSG00000022945(gene)|ensembl:ENSMUST00000023666(transcript)|ensembl:ENSMUST00000117099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:OOl2y6PVkqhk5ugd6rvt3bt/0ho10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P63085 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-397697|uniprotkb:P27703|uniprotkb:Q3V1U6|ensembl:ENSMUSP00000156154|ensembl:ENSMUSP00000065983|ensembl:ENSMUSP00000111396 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mk01_mouse(display_long)|uniprotkb:Mapk1(gene name)|psi-mi:Mapk1(display_short)|uniprotkb:Erk2(gene name synonym)|uniprotkb:Mapk(gene name synonym)|uniprotkb:Prkm1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001033752.1|refseq:NP_036079.1|refseq:XP_006522210.1|dip:DIP-661N|ensembl:ENSMUST00000069107(transcript)|ensembl:ENSMUST00000115731(transcript)|ensembl:ENSMUST00000232611(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P63085|reactome:R-MMU-111995|reactome:R-MMU-112409|reactome:R-MMU-112411|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-437239|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6798695|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211|reactome:R-MMU-9627069|reactome:R-MMU-9634635|ensembl:ENSMUSG00000063358(gene)|reactome:R-MMU-9634638|reactome:R-MMU-982772 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4STZhl2O+Ilh0lj8wQp8y2vVehA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8K3G5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988759|uniprotkb:Q921W6|ensembl:ENSMUSP00000002275 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:vrk3_mouse(display_long)|uniprotkb:Vrk3(gene name)|psi-mi:Vrk3(display_short)|uniprotkb:Serine/threonine-protein pseudokinase VRK3(gene name synonym)|uniprotkb:Vaccinia-related kinase 3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598706.1|refseq:XP_006540601.1|ensembl:ENSMUSG00000002205(gene)|ensembl:ENSMUST00000002275(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026870|reactome:R-MMU-202670|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Qioitr8/szoFE6K9qS4zrxV2L6o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P68181 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-400685|uniprotkb:P05206|uniprotkb:Q3TQH5|uniprotkb:Q3UDD0|uniprotkb:Q3UTH5|ensembl:ENSMUSP00000099573 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:kapcb_mouse(display_long)|uniprotkb:Prkacb(gene name)|psi-mi:Prkacb(display_short)|uniprotkb:Pkacb(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001157670.1|refseq:NP_001157671.1|refseq:NP_001157672.1|refseq:NP_035230.1|ensembl:ENSMUSG00000005034(gene)|ensembl:ENSMUST00000102515(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P68181|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8963896|reactome:R-MMU-983231 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:9278c8xZsjU90+vryXpzUc0y/G010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q08943 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2657613|uniprotkb:Q3U9Z2|uniprotkb:Q3UJ75|uniprotkb:Q4V9U4|uniprotkb:Q8CGA6|ensembl:ENSMUSP00000076971|ensembl:ENSMUSP00000127058 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ssrp1_mouse(display_long)|uniprotkb:Ssrp1(gene name)|psi-mi:Ssrp1(display_short)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001129553.1|refseq:NP_892035.2|refseq:XP_006499133.1|ensembl:ENSMUSG00000027067(gene)|ensembl:ENSMUST00000077798(transcript)|ensembl:ENSMUST00000168266(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08943|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6804756|reactome:R-MMU-75955 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QLbUR9V6OGtMwfD2fiZy4wEJwWE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P43276 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-903960|uniprotkb:Q9CRM8|ensembl:ENSMUSP00000079356 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h15_mouse(display_long)|uniprotkb:H1-5(gene name)|psi-mi:H1-5(display_short)|uniprotkb:H1 VAR.5(gene name synonym)|uniprotkb:H1b(gene name synonym)|uniprotkb:H1f5(gene name synonym)|uniprotkb:Hist1h1b(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_064418.1|ensembl:ENSMUSG00000058773(gene)|ensembl:ENSMUST00000080511(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43276|reactome:R-MMU-140342|reactome:R-MMU-2559584 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:XG7QIbZHXPP+4PO4OY4XdcBAZlc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UI84 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988719|ensembl:ENSMUSP00000110995 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3ui84_mouse(display_long)|uniprotkb:Rfc4(gene name)|psi-mi:Rfc4(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000022881(gene)|ensembl:ENSMUST00000115338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4iJPxjVrc/CIiyUzfBJRC7qcNYM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QYA2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2934825|ensembl:ENSMUSP00000032555|ensembl:ENSMUSP00000104090|uniprotkb:Q3TBZ2|uniprotkb:Q3TQA1|uniprotkb:Q8VI26|uniprotkb:Q8VI27|uniprotkb:Q9Z2N1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tom40_mouse(display_long)|uniprotkb:Tomm40(gene name)|psi-mi:Tomm40(display_short)|uniprotkb:Mom35(gene name synonym)|uniprotkb:Tom40(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein of 35 kDa(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000002984(gene)|ensembl:ENSMUST00000032555(transcript)|ensembl:ENSMUST00000093552(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0070678"(preprotein binding)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|reactome:R-MMU-5205685|refseq:NP_001103218.1|refseq:NP_058567.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:uLvvIUNClH260oadgLPk+suS/4U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O08579 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3043874|ensembl:ENSMUSP00000002029|uniprotkb:Q3TIH6|uniprotkb:Q3UJP3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:emd_mouse(display_long)|uniprotkb:Emd(gene name)|psi-mi:Emd(display_short)|uniprotkb:Sta(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000001964(gene)|ensembl:ENSMUST00000002029(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:O08579|reactome:R-MMU-4419969|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9609523|go:"GO:0031616"(spindle pole centrosome)|refseq:NP_031953.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Zw6awIQkodBfj6LHWEV9HpK8+VY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q921I0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988663|uniprotkb:Q8BK13|ensembl:ENSMUSP00000027266 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:orml1_mouse(display_long)|uniprotkb:Ormdl1(gene name)|psi-mi:Ormdl1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_663492.3|ensembl:ENSMUSG00000026097(gene)|ensembl:ENSMUST00000027266(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042552"(myelination)|go:"GO:0061744"(motor behavior)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:2000303"(regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|interpro:IPR029884|reactome:R-MMU-1660661 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pUNe0GSQp9Z4WQRbQF+I9po1BiM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CZG9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988779|ensembl:ENSMUSP00000015812|ensembl:ENSMUSP00000051068 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pdz11_mouse(display_long)|uniprotkb:Pdzd11(gene name)|psi-mi:Pdzd11(display_short)|uniprotkb:Pdzk11(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_082579.1|refseq:XP_006528365.1|refseq:XP_011245987.1|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1WI2|reactome:R-MMU-196780|reactome:R-MMU-199220|reactome:R-MMU-425397|reactome:R-MMU-6803544|reactome:R-MMU-936837|ensembl:ENSMUSG00000015668(gene)|ensembl:ENSMUST00000015812(transcript)|ensembl:ENSMUST00000059099(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:uOUhwCRMCnBEeWTJFzIGb4LKHOM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UJN9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988848 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3ujn9_mouse(display_long)|uniprotkb:Coil(gene name)|psi-mi:Coil(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR024822|interpro:IPR031722|go:"GO:0005634"(nucleus) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:zWMqZOYCToLKxDA3FoLX4TQNpi410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P15864 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-913436|ensembl:ENSMUSP00000045816 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h12_mouse(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1 VAR.1(gene name synonym)|uniprotkb:H1c(gene name synonym)|uniprotkb:H1f2(gene name synonym)|uniprotkb:Hist1h1c(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_056601.1|ensembl:ENSMUSG00000036181(gene)|ensembl:ENSMUST00000040914(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P15864|reactome:R-MMU-140342|reactome:R-MMU-2559584|dip:DIP-35245N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:xZTLhoQ8/vdiyHIxpxFNUWquFf810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P23198 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-78162|uniprotkb:Q921C4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cbx3_mouse(display_long)|uniprotkb:Cbx3(gene name)|psi-mi:Cbx3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:M32(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|reactome:R-MMU-73772|reactome:R-MMU-8953750|dip:DIP-28136N|mint:P23198 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:mD/Ut3JqLl3k0Ut98GxlstErEGs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z277 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-927576|uniprotkb:Q9CU68|uniprotkb:B9EJ99|uniprotkb:Q3URP5|uniprotkb:Q3USR7|uniprotkb:Q3UVM2|uniprotkb:Q8CAU9|ensembl:ENSMUSP00000002825 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:baz1b_mouse(display_long)|uniprotkb:Baz1b(gene name)|psi-mi:Baz1b(display_short)|uniprotkb:Wbscr9(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 9 protein homolog(gene name synonym)|uniprotkb:Wstf(gene name synonym)|uniprotkb:Bromodomain adjacent to zinc finger domain protein 1B(gene name synonym)|uniprotkb:Williams syndrome transcription factor homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035844.2|refseq:XP_011239182.1|dip:DIP-36072N|ensembl:ENSMUSG00000002748(gene)|ensembl:ENSMUST00000002825(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0035173"(histone kinase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037375|mint:Q9Z277|reactome:R-MMU-5250924|reactome:R-MMU-5693565 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vNCRFsXEsrl6HvyoxFL0kgVb7F410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P46061 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1033051|uniprotkb:Q60801|uniprotkb:Q6NZB5|ensembl:ENSMUSP00000057771|ensembl:ENSMUSP00000126849|ensembl:ENSMUSP00000130046 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ragp1_mouse(display_long)|uniprotkb:Rangap1(gene name)|psi-mi:Rangap1(display_short)|uniprotkb:Fug1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001139646.1|refseq:NP_035371.4|ensembl:ENSMUSG00000022391(gene)|ensembl:ENSMUST00000052374(transcript)|ensembl:ENSMUST00000170134(transcript)|ensembl:ENSMUST00000171115(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46061|rcsb pdb:1KPS|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108232|reactome:R-MMU-4615885|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025|dip:DIP-17024N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:XrJlIJ7cGqaUyNGBsK1ifk0YbmU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CPW4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2693825|uniprotkb:Q3U9T3|uniprotkb:Q9D8E7|ensembl:ENSMUSP00000076933 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arpc5_mouse(display_long)|uniprotkb:Arpc5(gene name)|psi-mi:Arpc5(display_short)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080645.2|ensembl:ENSMUSG00000008475(gene)|ensembl:ENSMUST00000077755(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043005"(neuron projection)|go:"GO:0051015"(actin filament binding)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0097581"(lamellipodium organization)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|rcsb pdb:7AQK|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-5663213|reactome:R-MMU-6798695|reactome:R-MMU-8856828|interpro:IPR036743|dip:DIP-60589N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+rfgpScVs8UqvIN7X557rXcn3eE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UJT6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988797 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3ujt6_mouse(display_long)|uniprotkb:Rfc1(gene name)|psi-mi:Rfc1(display_short)|uniprotkb:Recc1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001357(BRCT)|interpro:IPR036420 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:0tQm4QNfx4zLqe8X+GHThOz2nTk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QZQ8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3508334|uniprotkb:Q91VZ2|uniprotkb:Q9QZQ7|ensembl:ENSMUSP00000016081 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h2ay_mouse(display_long)|uniprotkb:Macroh2a1(gene name)|psi-mi:Macroh2a1(display_short)|uniprotkb:H2A.y(gene name synonym)|uniprotkb:H2A/y(gene name synonym)|uniprotkb:H2afy(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001152985.1|refseq:NP_001152986.1|refseq:NP_001152987.1|refseq:NP_036145.1|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:0005730"(nucleolus)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|go:"GO:0005813"(centrosome)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|interpro:IPR032454|go:"GO:0007549"(dosage compensation)|interpro:IPR035796|interpro:IPR043472|mint:Q9QZQ8|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|ensembl:ENSMUSG00000015937(gene)|ensembl:ENSMUST00000016081(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:70q7YQGYxyE7ZBq8e7oOsIUSY0810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UM65 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988805|ensembl:ENSMUSP00000023673 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3um65_mouse(display_long)|uniprotkb:Runx1(gene name)|psi-mi:Runx1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001104491.1|ensembl:ENSMUSG00000022952(gene)|ensembl:ENSMUST00000023673(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QLMeHixBXR17wtrsDa3W1iu+QrA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BT07 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P10922 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-529651|uniprotkb:Q3UKC0|ensembl:ENSMUSP00000137309 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:h10_mouse(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1f0(gene name synonym)|uniprotkb:H1fv(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym)|uniprotkb:MyD196(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032223.2|ensembl:ENSMUSG00000096210(gene)|ensembl:ENSMUST00000180086(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10922|reactome:R-MMU-140342|reactome:R-MMU-2559584 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:O/PNarQrFWH/SALoDATRxhetTEA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q62150 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988676 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q62150_mouse(display_long)|uniprotkb:Rnps1(gene name)|psi-mi:Rnps1(display_short)|uniprotkb:RNPS1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034201|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR035979 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:g8PsHkXq63kYOlSaMdyuRISu/sY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9ERK4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-400836|intact:EBI-4283823|ensembl:ENSMUSP00000002790 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:xpo2_mouse(display_long)|uniprotkb:Cse1l(gene name)|psi-mi:Cse1l(display_short)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Xpo2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_076054.1|ensembl:ENSMUSG00000002718(gene)|ensembl:ENSMUST00000002790(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9ERK4 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vJpTu+2YjwIRrjM3V815K3lZzAg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O08602 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988685|uniprotkb:B9EI05 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rae1a_mouse(display_long)|uniprotkb:Raet1a(gene name)|psi-mi:Raet1a(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033042.1|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR029287|go:"GO:0005615"(extracellular space)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071360"(cellular response to exogenous dsRNA)|interpro:IPR037055 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5fuCLtvh22fhRDH7OTqMgG09yqs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQQ7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2935050|ensembl:ENSMUSP00000113022 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:at5f1_mouse(display_long)|uniprotkb:Atp5pb(gene name)|psi-mi:Atp5pb(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:Atp5f1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000000563(gene)|ensembl:ENSMUST00000118209(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:Q9CQQ7|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_033855.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:g22oBc1YXUjxPlMIN/TbpQrIXEg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BHE0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989950|uniprotkb:B2KGQ3|uniprotkb:Q3V3H1|ensembl:ENSMUSP00000060803 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prr11_mouse(display_long)|uniprotkb:Prr11(gene name)|psi-mi:Prr11(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_780772.1|ensembl:ENSMUSG00000020493(gene)|ensembl:ENSMUST00000051395(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051726"(regulation of cell cycle) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:FgQqUMKQ4AJFCuEijOC9yvHj8Lk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DAP7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2657838|uniprotkb:Q8BP41|uniprotkb:Q9CTX3|ensembl:ENSMUSP00000005607 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:asf1b_mouse(display_long)|uniprotkb:Asf1b(gene name)|psi-mi:Asf1b(display_short)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_077146.1|ensembl:ENSMUSG00000005470(gene)|ensembl:ENSMUST00000005607(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jmwl+lmm6PjOGHFhGLdDVs16xdA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70288 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-302251|uniprotkb:B2RRP3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3U8W9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989913 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3u8w9_mouse(display_long)|uniprotkb:Hnrnpr(gene name)|psi-mi:Hnrnpr(display_short)|uniprotkb:Hnrpr(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001264050.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR034411|interpro:IPR035979|interpro:IPR041337 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:DSRvudcJgsjxDdyuRUYo1AbmIgg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z130 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-299668|uniprotkb:Q9CT01 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hnrdl_mouse(display_long)|uniprotkb:Hnrnpdl(gene name)|psi-mi:Hnrnpdl(display_short)|uniprotkb:Hnrpdl(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:Jktbp(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0034046"("poly(G) binding")|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016071"(mRNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034847|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q9Z130|interpro:IPR035979 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:tuixz3AUwmb7edjq5GOsKvOB9QE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99ME9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4285566|uniprotkb:Q99K16|uniprotkb:Q99P78|uniprotkb:Q9CT02|ensembl:ENSMUSP00000152412 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gtpb4_mouse(display_long)|uniprotkb:Gtpbp4(gene name)|psi-mi:Gtpbp4(display_short)|uniprotkb:Crfg(gene name synonym)|uniprotkb:Nog1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081276.2|ensembl:ENSMUSG00000021149(gene)|ensembl:ENSMUST00000222098(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q99ME9 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:bcJx83SRfrtIzUbasVwCDleHiR010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R0Q4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989979|uniprotkb:A2AEB2|uniprotkb:Q3UL62|uniprotkb:Q6DIB1|uniprotkb:Q6ZQK7|uniprotkb:Q8C201|uniprotkb:Q8C6C2|ensembl:ENSMUSP00000033797|ensembl:ENSMUSP00000108720|ensembl:ENSMUSP00000108722|ensembl:ENSMUSP00000126363|ensembl:ENSMUSP00000129774|ensembl:ENSMUSP00000132643|ensembl:ENSMUSP00000131909 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mo4l2_mouse(display_long)|uniprotkb:Morf4l2(gene name)|psi-mi:Morf4l2(display_short)|uniprotkb:Kiaa0026(gene name synonym)|uniprotkb:Sid393(gene name synonym)|uniprotkb:MORF-related gene X protein(gene name synonym)|uniprotkb:Sid 393(gene name synonym)|uniprotkb:Transcription factor-like protein MRGX(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001161697.1|refseq:NP_001161698.1|refseq:NP_001161699.1|refseq:NP_001161700.1|refseq:NP_001161701.1|refseq:NP_001161702.1|refseq:NP_062742.4|refseq:XP_006528647.1|ensembl:ENSMUSG00000031422(gene)|ensembl:ENSMUST00000033797(transcript)|ensembl:ENSMUST00000080411(transcript)|ensembl:ENSMUST00000113097(transcript)|ensembl:ENSMUST00000164609(transcript)|ensembl:ENSMUST00000166478(transcript)|ensembl:ENSMUST00000166930(transcript)|ensembl:ENSMUST00000169418(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|interpro:IPR008676(MRG)|interpro:IPR026541|interpro:IPR038012|interpro:IPR038217 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:OANRPe5bROddeJR9FHsJeANJFko10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QZ83 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1183650 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P60122 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1634999|uniprotkb:O35753|ensembl:ENSMUSP00000032165 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ruvb1_mouse(display_long)|uniprotkb:Ruvbl1(gene name)|psi-mi:Ruvbl1(display_short)|uniprotkb:Tip49(gene name synonym)|uniprotkb:Tip49a(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:DNA helicase p50(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062659.1|ensembl:ENSMUSG00000030079(gene)|ensembl:ENSMUST00000032165(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:P60122|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5696394|reactome:R-MMU-606279 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:fZiQ7AurvKII0LYc+haBswAXfZ410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D3G5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989961 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:stx11_mouse(display_long)|uniprotkb:Stx11(gene name)|psi-mi:Stx11(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_083351.1|interpro:IPR028672|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)|interpro:IPR000727(Target SNARE coiled-coil region)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0043316"(cytotoxic T cell degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR042781 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:sw0Y6nP+MBAZK/W3ItYO9ZRFoPM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922Q8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-647863|uniprotkb:Q3TJ35|uniprotkb:Q3TLC7|uniprotkb:Q3TWT9|uniprotkb:Q3TX86|ensembl:ENSMUSP00000021239 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:lrc59_mouse(display_long)|uniprotkb:Lrrc59(gene name)|psi-mi:Lrrc59(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598568.1|ensembl:ENSMUSG00000020869(gene)|ensembl:ENSMUST00000021239(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q922Q8 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Y2nzjMFwQhLMP697NokEz+jOLUM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UK75 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989864 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3uk75_mouse(display_long)|uniprotkb:Rp9(gene name)|psi-mi:Rp9(display_short)|uniprotkb:rp9(gene name synonym)|uniprotkb:Rp9h(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0008380"(RNA splicing)|interpro:IPR034585 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:C5d/JJXPgLDdVteJAxlSBKVRusM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0F6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1180268|ensembl:ENSMUSP00000083652 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rfc5_mouse(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:Rfc5(gene name)|psi-mi:Rfc5(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_082404.1|ensembl:ENSMUSG00000029363(gene)|ensembl:ENSMUST00000086461(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:Q9D0F6|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+qImp1uvdRn0WSnuNK0y8KJ9fIs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q07832 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2552999|ensembl:ENSMUSP00000033154 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:plk1_mouse(display_long)|uniprotkb:Plk(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:Plk1(gene name)|psi-mi:Plk1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000030867(gene)|ensembl:ENSMUST00000033154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|interpro:IPR033702|interpro:IPR036947|rcsb pdb:5DMS|rcsb pdb:5DMV|rcsb pdb:5DNJ|rcsb pdb:5X3S|reactome:R-MMU-141444|reactome:R-MMU-156711|reactome:R-MMU-162658|reactome:R-MMU-174178|reactome:R-MMU-176412|reactome:R-MMU-176417|reactome:R-MMU-2299718|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2980767|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-68881|reactome:R-MMU-68884|reactome:R-MMU-69273|reactome:R-MMU-8852276|reactome:R-MMU-8854518|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|go:"GO:0000070"(mitotic sister chromatid segregation)|reactome:R-MMU-9648025|refseq:NP_035251.3|dip:DIP-56722N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:YqF9DFVZSOmxF6QvN/X+kabo0lQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q05CR0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989857 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q05cr0_mouse(display_long)|uniprotkb:LOC72520(gene name)|psi-mi:LOC72520(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR003036(Core shell protein Gag P30)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|go:"GO:0019068"(virion assembly) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:uvV83ROj/edJj1GhMGQQ4dRGB3s10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q76MZ3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-400413|ensembl:ENSMUSP00000007708 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:0tnO11U1SNOOT46j23f7dim8O8k10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q5FW75 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989889 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q5fw75_mouse(display_long)|uniprotkb:Actn2(gene name)|psi-mi:Actn2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|refseq:NP_150371.4|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|interpro:IPR036872 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:tHTCxcvdDKeWTHbEzCJKSqQIi3810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WTX5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1202363|uniprotkb:Q8C5H6|ensembl:ENSMUSP00000038744|ensembl:ENSMUSP00000104700 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:skp1_mouse(display_long)|uniprotkb:Skp1(gene name)|psi-mi:Skp1(display_short)|uniprotkb:Skp1a(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035673.3|refseq:XP_006532849.1|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000036309(gene)|ensembl:ENSMUST00000037324(transcript)|ensembl:ENSMUST00000109072(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:Q9WTX5|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168|dip:DIP-38596N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qGk720KMKAbBPguy2tmUOZsLxRQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9EQX4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1634547|uniprotkb:Q8C150|ensembl:ENSMUSP00000001920 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:aif1l_mouse(display_long)|uniprotkb:Iba2(gene name synonym)|uniprotkb:Ionized calcium-binding adapter molecule 2(gene name synonym)|uniprotkb:Aif1l(gene name)|psi-mi:Aif1l(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_660126.1|ensembl:ENSMUSG00000001864(gene)|ensembl:ENSMUST00000001920(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0097178"(ruffle assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR028453|interpro:IPR042433 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/ALMwhv/lHihdH7qdfjLIyKB1Ek10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q923T9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-771638|uniprotkb:Q3U3H3|uniprotkb:Q8VED3|ensembl:ENSMUSP00000071720 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:kcc2g_mouse(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001034227.1|refseq:NP_001034228.1|refseq:NP_848712.2|ensembl:ENSMUSG00000021820(gene)|ensembl:ENSMUST00000071816(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q923T9|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pbJqcEUQJQRnAwcKozmS72n9s1w10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R190 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-904134|uniprotkb:Q3TVT8|ensembl:ENSMUSP00000093959 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mta2_mouse(display_long)|uniprotkb:Mta2(gene name)|psi-mi:Mta2(display_short)|uniprotkb:Mta1l1(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035972.3|dip:DIP-36630N|ensembl:ENSMUSG00000071646(gene)|ensembl:ENSMUST00000096240(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:Q9R190|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:iHG+WZKTCRwTvC7LdS7OayvcEuA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3U8B3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989925 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3u8b3_mouse(display_long)|uniprotkb:Rpa1(gene name)|psi-mi:Rpa1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|refseq:NP_001157695.1|interpro:IPR031657|go:"GO:0003677"(DNA binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016605"(PML body)|go:"GO:0046872"(metal ion binding) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:I0NC8sDRFcQDWT5hD9rgsv1F3Zc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62843 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2526764|uniprotkb:P11174|uniprotkb:Q52KC9|ensembl:ENSMUSP00000069004 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rs15_mouse(display_long)|uniprotkb:Rps15(gene name)|psi-mi:Rps15(display_short)|uniprotkb:Rig(gene name synonym)|uniprotkb:RIG protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000063457(gene)|ensembl:ENSMUST00000068408(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|interpro:IPR023575|mint:P62843|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_033117.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:lJJOew1txuTwFlhKu4Z+AkPS5H010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:E9PVA8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4284669|intact:EBI-6908505|uniprotkb:B2RWW6|ensembl:ENSMUSP00000069432 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:gcn1_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:Gcn1l1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_766307.2|ensembl:ENSMUSG00000041638(gene)|ensembl:ENSMUST00000064454(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:E9PVA8 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:KX5ViHlt2ZOUAv/9GRSRAMijpE010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R0Q7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6913887|ensembl:ENSMUSP00000050292|uniprotkb:Q542V4|uniprotkb:Q9D7V0|uniprotkb:Q9WV83 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tebp_mouse(display_long)|uniprotkb:Ptges3(gene name)|psi-mi:Ptges3(display_short)|uniprotkb:Sid3177(gene name synonym)|uniprotkb:Tebp(gene name synonym)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:Sid 3177(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000071072(gene)|ensembl:ENSMUST00000052798(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002039"(p53 binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006457"(protein folding)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050220"(prostaglandin-E synthase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060430"(lung saccule development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9R0Q7|reactome:R-MMU-2162123|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9018519|refseq:NP_062740.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:YMwjVAVwK01RvPxKbe3JEiBa6vI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D898 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-910972|intact:EBI-11516803|ensembl:ENSMUSP00000108483 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arp5l_mouse(display_long)|uniprotkb:Arp2/3 complex 16 kDa subunit 2(gene name synonym)|uniprotkb:Arpc5l(gene name)|psi-mi:Arpc5l(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_083085.1|ensembl:ENSMUSG00000026755(gene)|ensembl:ENSMUST00000112862(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016477"(cell migration)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|mint:Q9D898 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6iegdWEHIoZchHChptwDifXGRVE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P29268 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988949|uniprotkb:G5E830|uniprotkb:Q922U0|ensembl:ENSMUSP00000020171 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ccn2_mouse(display_long)|uniprotkb:Protein FISP-12(gene name synonym)|uniprotkb:betaIG-M2(gene name synonym)|uniprotkb:Ccn2(gene name)|psi-mi:Ccn2(display_short)|uniprotkb:Cellular communication network factor 2(gene name synonym)|uniprotkb:Connective tissue growth factor(gene name synonym)|uniprotkb:Ctgf(gene name synonym)|uniprotkb:Fisp-12(gene name synonym)|uniprotkb:Fisp12(gene name synonym)|uniprotkb:Hcs24(gene name synonym)|uniprotkb:Hypertrophic chondrocyte-specific protein 24(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034347.2|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034059"(response to anoxia)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|ensembl:ENSMUSG00000019997(gene)|ensembl:ENSMUST00000020171(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061448"(connective tissue development)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0007165"(signal transduction) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HvOgb8vLDLHMV8+R15D1qvE87eU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91VR2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-444750|ensembl:ENSMUSP00000110547 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:atpg_mouse(display_long)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:Atp5c1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_065640.2|ensembl:ENSMUSG00000025781(gene)|ensembl:ENSMUST00000114897(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|reactome:R-MMU-163210|reactome:R-MMU-8949613 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HXjj4Rj2J2QsW3UFM47mHOYS2VI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3U1J4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2552275|ensembl:ENSMUSP00000025649|uniprotkb:Q99LV3|uniprotkb:Q9QYK0|uniprotkb:Q3U8G3|uniprotkb:Q9WV39|uniprotkb:Q3UJC4|uniprotkb:Q3U4D0 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ddb1_mouse(display_long)|uniprotkb:Ddb1(gene name)|psi-mi:Ddb1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000024740(gene)|ensembl:ENSMUST00000025649(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_056550.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|mint:Q3U1J4|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|go:"GO:0005654"(nucleoplasm)|dip:DIP-56812N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:dvNwCrG9In1FV2j/+PrsSMvqFnk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TXJ4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989115 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3txj4_mouse(display_long)|uniprotkb:Sar1a(gene name)|psi-mi:Sar1a(display_short)|uniprotkb:Sara1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR006687(GTP-binding protein SAR1)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:50T54jIqSp+Q+9K90+4NkXCAjxM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D1M0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4285415|uniprotkb:Q99M12|uniprotkb:Q9D712|ensembl:ENSMUSP00000032440 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sec13_mouse(display_long)|uniprotkb:Sec13(gene name)|psi-mi:Sec13(display_short)|uniprotkb:Sec13l1(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_077168.2|ensembl:ENSMUSG00000030298(gene)|ensembl:ENSMUST00000032440(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037363|interpro:IPR037596|mint:Q9D1M0|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-204005|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9639288|reactome:R-MMU-9648025|reactome:R-MMU-983170|interpro:IPR036322 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:40KHYuvc/jVIxhLJTKivv2NRm7I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TLP8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2311484|ensembl:ENSMUSP00000098058 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tlp8_mouse(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001334459.1|ensembl:ENSMUSG00000001847(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|ensembl:ENSMUST00000100489(transcript) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:voc4DAtejAIA25w+N8+IalVqNiE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BP47 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-646438|uniprotkb:Q3T9A7|uniprotkb:Q7TPX0|uniprotkb:Q9CRY5|ensembl:ENSMUSP00000157402 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sync_mouse(display_long)|uniprotkb:NARS1(gene name)|psi-mi:NARS1(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)|uniprotkb:Asparaginyl-tRNA synthetase 1(gene name synonym)|uniprotkb:Nars(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001136422.1|refseq:NP_081626.2|ensembl:ENSMUSG00000024587(gene)|ensembl:ENSMUST00000237400(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004816"(asparagine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006421"(asparaginyl-tRNA aminoacylation)|go:"GO:0016477"(cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031728"(CCR3 chemokine receptor binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q8BP47 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:xEpYdPecGJVWRFHZdcicBbtHicw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9WUB4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988920|uniprotkb:Q8C2M9|uniprotkb:Q9QZB8|ensembl:ENSMUSP00000033913 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dctn6_mouse(display_long)|uniprotkb:Dctn6(gene name)|psi-mi:Dctn6(display_short)|uniprotkb:Ws3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001280686.1|refseq:NP_001280687.1|refseq:NP_001280688.1|refseq:NP_035852.1|ensembl:ENSMUSG00000031516(gene)|ensembl:ENSMUST00000033913(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003824"(catalytic activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:Q9WUB4|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Dd+/GShX4ejVZ07DseNGbUUyJYg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3THS6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989148|uniprotkb:Q3TL60|uniprotkb:Q76LX3|ensembl:ENSMUSP00000087118 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:metk2_mouse(display_long)|uniprotkb:Mat2a(gene name)|psi-mi:Mat2a(display_short)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_663544.1|ensembl:ENSMUSG00000053907(gene)|ensembl:ENSMUST00000059472(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009725"(response to hormone)|go:"GO:0016597"(amino acid binding)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051591"(response to cAMP)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-MMU-156581|go:"GO:0005524"(ATP binding)|dip:DIP-59526N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/uQbUnTVd7NzvMsIZyyNmjt357o10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQ71 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3043958|ensembl:ENSMUSP00000012627 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rfa3_mouse(display_long)|uniprotkb:Rpa3(gene name)|psi-mi:Rpa3(display_short)|uniprotkb:Replication factor A protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000012483(gene)|ensembl:ENSMUST00000012627(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174437|reactome:R-MMU-176187|reactome:R-MMU-3371453|reactome:R-MMU-5358565|reactome:R-MMU-5358606|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-5696395|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6783310|reactome:R-MMU-6804756|reactome:R-MMU-68962|reactome:R-MMU-69166|reactome:R-MMU-69473|refseq:NP_080908.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vKHzYwRnC8SqPLSMsx0WgQowtms10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70257 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2639047|uniprotkb:O08519|uniprotkb:P70258|uniprotkb:Q64192|uniprotkb:Q99L78|uniprotkb:Q9R1G2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nfix_mouse(display_long)|uniprotkb:Nfix(gene name)|psi-mi:Nfix(display_short)|uniprotkb:Nuclear factor I/X(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001075451.1|refseq:NP_035036.1|interpro:IPR000647(CTF/NF-I)|interpro:IPR020604|interpro:IPR019739|interpro:IPR019548|interpro:IPR003619(MAD homology 1, Dwarfin-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021549"(cerebellum development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:P70257 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5TGzlF8pDJ85EBsxigizYV1O7U010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O55128 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3T9V8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9988907 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3t9v8_mouse(display_long)|uniprotkb:Dctn1(gene name)|psi-mi:Dctn1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|go:"GO:0005938"(cell cortex)|go:"GO:0030286"(dynein complex)|interpro:IPR036859 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:0jAVyWOrkbyNsx+xhiu9wbYZr0E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70168 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-540580|uniprotkb:Q62117|uniprotkb:Q6GTI5|ensembl:ENSMUSP00000001479 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:imb1_mouse(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:SCG(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Impnb(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032405.3|ensembl:ENSMUSG00000001440(gene)|ensembl:ENSMUST00000001479(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|reactome:R-MMU-2995383|reactome:R-MMU-6798695|reactome:R-MMU-909733|reactome:R-MMU-1655829|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:P70168|rcsb pdb:1GCJ|rcsb pdb:1UKL|go:"GO:0019894"(kinesin binding)|reactome:R-MMU-140342|dip:DIP-33404N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:rYDCcZYUZp8TbcpyJE7pfz5+bvo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BG05 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2735601|uniprotkb:Q8BHF8|ensembl:ENSMUSP00000088298|ensembl:ENSMUSP00000107595 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:roa3_mouse(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_444493.1|refseq:NP_666242.2|refseq:NP_932758.1|ensembl:ENSMUSG00000059005(gene)|ensembl:ENSMUST00000090792(transcript)|ensembl:ENSMUST00000111964(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q8BG05|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:XP_011237818.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6NSQ7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4285341|uniprotkb:Q9D0F5|ensembl:ENSMUSP00000019950 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ltv1_mouse(display_long)|uniprotkb:Ltv1(gene name)|psi-mi:Ltv1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_852135.1|ensembl:ENSMUSG00000019814(gene)|ensembl:ENSMUST00000019950(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007307(Low temperature viability protein)|reactome:R-MMU-6791226 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:sA3lTXSfpu0n+dTRe5R5q3JdbjY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q61699 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772450|uniprotkb:Q3TNS2|uniprotkb:Q3UIY8|uniprotkb:Q62578|uniprotkb:Q62579|uniprotkb:Q6A0A5|uniprotkb:Q8C430|uniprotkb:Q8VCW6|ensembl:ENSMUSP00000144413|ensembl:ENSMUSP00000144654 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hs105_mouse(display_long)|uniprotkb:Heat shock-related 100 kDa protein E7I(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:42 degrees C-HSP(gene name synonym)|uniprotkb:Hsph1(gene name)|psi-mi:Hsph1(display_short)|uniprotkb:Hsp105(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Kiaa0201(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_038587.2|refseq:NP_001334463.1|dip:DIP-32354N|ensembl:ENSMUSG00000029657(gene)|ensembl:ENSMUST00000201452(transcript)|ensembl:ENSMUST00000202361(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q61699|reactome:R-MMU-3371453 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pZByRgd8f5XdmB138rYxEMrwkRY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91WN1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2657776|uniprotkb:Q3TSG3|uniprotkb:Q8R0E3|ensembl:ENSMUSP00000022345 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dnjc9_mouse(display_long)|uniprotkb:Dnajc9(gene name)|psi-mi:Dnajc9(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_598842.1|go:"GO:0005829"(cytosol)|ensembl:ENSMUSG00000021811(gene)|ensembl:ENSMUST00000022345(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:npkrpswDe+pHwlDqgV/B8irW1GA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91YR7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6876849|ensembl:ENSMUSP00000002529|ensembl:ENSMUSP00000121340|uniprotkb:Q3ULJ7|uniprotkb:Q542P0|uniprotkb:Q8CIK9|uniprotkb:Q8R3M8|uniprotkb:Q99JN1|uniprotkb:Q9CSZ0 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:prp6_mouse(display_long)|uniprotkb:Prpf6(gene name)|psi-mi:Prpf6(display_short)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000002455(gene)|ensembl:ENSMUST00000002529(transcript)|ensembl:ENSMUST00000136481(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:Q91YR7|rcsb pdb:6QX9|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_598462.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:dxGQPYKGfgDyylKz6TISBJfMIBs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q62388 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1202183|uniprotkb:E9QNY7|ensembl:ENSMUSP00000156344 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:atm_mouse(display_long)|uniprotkb:Atm(gene name)|psi-mi:Atm(display_short)|uniprotkb:Ataxia telangiectasia mutated homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_031525.2|ensembl:ENSMUSG00000034218(gene)|ensembl:ENSMUST00000232179(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0002331"(pre-B cell allelic exclusion)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007292"(female gamete generation)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008585"(female gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0090399"(replicative senescence)|go:"GO:0097694"(establishment of RNA localization to telomere)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903626"(positive regulation of DNA catabolic process)|go:"GO:1903978"(regulation of microglial cell activation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904354"(negative regulation of telomere capping)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904884"(positive regulation of telomerase catalytic core complex assembly)|go:"GO:1905843"(regulation of cellular response to gamma radiation)|go:"GO:1990391"(DNA repair complex)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR015519(Ataxia-Telangiectasia Mutated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR044107|reactome:R-MMU-2559586|reactome:R-MMU-3371453|reactome:R-MMU-349425|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693548|reactome:R-MMU-5693565|reactome:R-MMU-5693568|reactome:R-MMU-5693571|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6803204|reactome:R-MMU-6803207|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804760|reactome:R-MMU-69473|reactome:R-MMU-69541|reactome:R-MMU-9664873|go:"GO:0071480"(cellular response to gamma radiation) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:5N+6mv9x1LhNivAkCZQyxStMDLw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0M5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-767129|uniprotkb:A7M7R8|uniprotkb:Q3TFB4|ensembl:ENSMUSP00000020775|ensembl:ENSMUSP00000103556|ensembl:ENSMUSP00000136241 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dyl2_mouse(display_long)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym)|uniprotkb:Dynll2(gene name)|psi-mi:Dynll2(display_short)|uniprotkb:Dlc2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001161943.1|refseq:NP_001161944.1|refseq:NP_080832.1|ensembl:ENSMUSG00000020483(gene)|ensembl:ENSMUST00000020775(transcript)|ensembl:ENSMUST00000107923(transcript)|ensembl:ENSMUST00000178105(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q9D0M5|rcsb pdb:1RE6|reactome:R-MMU-139910|reactome:R-MMU-141444|reactome:R-MMU-1632852|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-5620924|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-9646399|reactome:R-MMU-9648025 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4RFpJF40RBja5mOvt/aCv3miiDU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P47757 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-299194|ensembl:ENSMUSP00000099565|uniprotkb:A2AMV7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:capzb_mouse(display_long)|uniprotkb:Capzb(gene name)|psi-mi:Capzb(display_short)|uniprotkb:Cappb1(gene name synonym)|uniprotkb:CapZ beta(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000028745(gene)|ensembl:ENSMUST00000102507(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0014069"(postsynaptic density)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0033150"(cytoskeletal calyx)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47757|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-9013405|reactome:R-MMU-9035034|reactome:R-MMU-983231|refseq:NP_001032850.1|refseq:NP_033928.1|refseq:NP_001258334.1|dip:DIP-31383N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:KuYsJ7bZNn4W7wMGSadohYIBWqM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0I9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-529738|uniprotkb:Q8VDW1|uniprotkb:Q3THP2|uniprotkb:Q3TM73|uniprotkb:Q3U8R2|uniprotkb:Q3U930|uniprotkb:Q5SXA8|ensembl:ENSMUSP00000018992 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:syrc_mouse(display_long)|uniprotkb:Rars1(gene name)|psi-mi:Rars1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:Rars(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080212.2|ensembl:ENSMUSG00000018848(gene)|ensembl:ENSMUST00000018992(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:Q9D0I9 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+1WhOMv/SKJ4+ILpXXgQKPx8Kqg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BRG8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989028|uniprotkb:Q80WQ3|uniprotkb:Q8BP02|uniprotkb:Q8C202|uniprotkb:Q8CDY5|ensembl:ENSMUSP00000110813|ensembl:ENSMUSP00000138292 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tm209_mouse(display_long)|uniprotkb:Tmem209(gene name)|psi-mi:Tmem209(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_848740.3|refseq:NP_001298022.1|refseq:XP_006505233.2|ensembl:ENSMUSG00000029782(gene)|ensembl:ENSMUST00000115160(transcript)|ensembl:ENSMUST00000138823(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019176 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:aEwbJlA9HmgCRiOYAUge/eK2rnw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:A2API8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989106|ensembl:ENSMUSP00000103226 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:a2api8_mouse(display_long)|uniprotkb:Pakap(gene name)|psi-mi:Pakap(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0008104"(protein localization)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR029304|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|ensembl:ENSMUSG00000038729(gene)|ensembl:ENSMUST00000107600(transcript)|go:"GO:0007015"(actin filament organization) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Dyh1wQC0y6v5JUhRR3LWsiDxggk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91ZW3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-927547|uniprotkb:Q8C791|uniprotkb:Q8CA22|uniprotkb:Q8VDG1|uniprotkb:Q925M9|ensembl:ENSMUSP00000044361 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:smca5_mouse(display_long)|uniprotkb:Smarca5(gene name)|psi-mi:Smarca5(display_short)|uniprotkb:Snf2h(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_444354.2|dip:DIP-36073N|ensembl:ENSMUSG00000031715(gene)|ensembl:ENSMUST00000043359(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:Q91ZW3|reactome:R-MMU-5250924|reactome:R-MMU-5693565|reactome:R-MMU-606279 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+HXPfdDGqKssFXooxGP7gM+u8Oc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3U7B3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989051 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3u7b3_mouse(display_long)|uniprotkb:Tmpo(gene name)|psi-mi:Tmpo(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR013146(Thymopoietin LEM)|interpro:IPR011015(LEM-like fold)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016021"(integral component of membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qTI/83II8CAXjtnj5WnsSlaIN1k10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D6F9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-911077|uniprotkb:Q62364|uniprotkb:Q80Y54|ensembl:ENSMUSP00000071135 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tbb4a_mouse(display_long)|uniprotkb:Tubb4a(gene name)|psi-mi:Tubb4a(display_short)|uniprotkb:Tubb4(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033477.2|ensembl:ENSMUSG00000062591(gene)|ensembl:ENSMUST00000071135(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0030030"(cell projection organization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033269"(internode region of axon)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR037103|mint:Q9D6F9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|interpro:IPR036525 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z2Z6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989063|uniprotkb:Q3U801|ensembl:ENSMUSP00000035222 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mcat_mouse(display_long)|uniprotkb:Slc25a20(gene name)|psi-mi:Slc25a20(display_short)|uniprotkb:Cac(gene name synonym)|uniprotkb:Cact(gene name synonym)|uniprotkb:Carnitine/acylcarnitine translocase(gene name synonym)|uniprotkb:Solute carrier family 25 member 20(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_065266.1|interpro:IPR023395|reactome:R-MMU-200425|interpro:IPR018108|ensembl:ENSMUSG00000032602(gene)|ensembl:ENSMUST00000035222(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015227"(acyl carnitine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902603"(carnitine transmembrane transport) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RX+Mbe4nGGozTzodiev81QsW3JM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6P5D8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6907867|ensembl:ENSMUSP00000121835|uniprotkb:Q6PDM8|uniprotkb:Q6PE93|uniprotkb:Q6ZQ78|uniprotkb:Q811H3|uniprotkb:Q8BP09|uniprotkb:Q9D4M7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:smhd1_mouse(display_long)|uniprotkb:Smchd1(gene name)|psi-mi:Smchd1(display_short)|uniprotkb:Kiaa0650(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000024054(gene)|ensembl:ENSMUST00000127430(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:Q6P5D8|rcsb pdb:6N64|refseq:NP_083163.3 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:hpvZulbZ6q3A01pCveP/AZKq2LU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:A2ARQ4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989082|ensembl:ENSMUSP00000097074 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:a2arq4_mouse(display_long)|uniprotkb:Serf2(gene name)|psi-mi:Serf2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001277766.1|ensembl:ENSMUSG00000074884(gene)|ensembl:ENSMUST00000099475(transcript)|interpro:IPR007513(Four F5 protein)|interpro:IPR040211 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:haQrXfEEC+5o4LtBTrtxcCHNVRM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q922M3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-5652023|ensembl:ENSMUSP00000099641 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:bacd3_mouse(display_long)|uniprotkb:Kctd10(gene name)|psi-mi:Kctd10(display_short)|uniprotkb:BTB/POZ domain-containing protein KCTD10(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001153413.1|refseq:NP_080421.2|ensembl:ENSMUST00000102581(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007507"(heart development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036038"(MKS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|ensembl:ENSMUSG00000001098(gene)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:L4mdKqImo6BHhMZNjdaAdMxnJXs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TC33 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989091|uniprotkb:Q3TPA8|uniprotkb:Q9CQ15|ensembl:ENSMUSP00000022063 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cc127_mouse(display_long)|uniprotkb:Ccdc127(gene name)|psi-mi:Ccdc127(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001162129.1|refseq:NP_001162130.1|refseq:NP_077163.1|ensembl:ENSMUSG00000021578(gene)|ensembl:ENSMUST00000022063(transcript)|interpro:IPR034607 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1hiiboRUiBM/uZuvJbuMwfp8ls410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P80318 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772361|ensembl:ENSMUSP00000001452 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q569Z6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2536252|ensembl:ENSMUSP00000079722 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tr150_mouse(display_long)|uniprotkb:Thrap3(gene name)|psi-mi:Thrap3(display_short)|uniprotkb:Trap150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000043962(gene)|ensembl:ENSMUST00000080919(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026667|interpro:IPR029199|go:"GO:0008380"(RNA splicing)|refseq:XP_011238805.1|refseq:NP_666265.3|refseq:XP_006503104.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Cb0vHuEX3Ew27z2gvfC/36tdeYE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TEA8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6665967|ensembl:ENSMUSP00000030541|ensembl:ENSMUSP00000132614|uniprotkb:A2AM64|uniprotkb:A2AM68|uniprotkb:Q3TM38|uniprotkb:Q3TU07|uniprotkb:Q61688|uniprotkb:Q8BT17|uniprotkb:Q8C6H2|uniprotkb:Q8C911|uniprotkb:Q8VE06|uniprotkb:Q99KR0|uniprotkb:Q9DBI1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hp1b3_mouse(display_long)|uniprotkb:Hp1bp3(gene name)|psi-mi:Hp1bp3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001272407.1|refseq:NP_001272408.1|refseq:NP_001272409.1|refseq:NP_001272410.1|ensembl:ENSMUSG00000028759(gene)|ensembl:ENSMUST00000030541(transcript)|ensembl:ENSMUST00000165861(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|mint:Q3TEA8|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|refseq:XP_006538631.1|refseq:XP_006538633.1|refseq:NP_001116368.1|refseq:NP_001116369.1|refseq:NP_034600.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:slrlB/B0DUfN8npc59xviu74mxs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DBF7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9989132|uniprotkb:A2A6F4|uniprotkb:Q6AXH2|uniprotkb:Q7TSF8|ensembl:ENSMUSP00000018685 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cwc25_mouse(display_long)|uniprotkb:Cwc25(gene name)|psi-mi:Cwc25(display_short)|uniprotkb:Ccdc49(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 49(gene name synonym)|uniprotkb:Spliceosome-associated protein homolog CWC25(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080462.2|ensembl:ENSMUSG00000018541(gene)|ensembl:ENSMUST00000018685(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR019339|go:"GO:0005634"(nucleus)|interpro:IPR022209|reactome:R-MMU-72163 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:O98dxmCRYK4nsfHrlrId4Ie6n/U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C4B4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986912|ensembl:ENSMUSP00000055475|uniprotkb:Q14BY8|uniprotkb:Q8BRC4|uniprotkb:Q922B4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:u119b_mouse(display_long)|uniprotkb:Unc119b(gene name)|psi-mi:Unc119b(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000046562(gene)|go:"GO:0005929"(cilium)|go:"GO:0007399"(nervous system development)|go:"GO:0008289"(lipid binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0060271"(cilium assembly)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR037036|reactome:R-MMU-5624138|ensembl:ENSMUST00000060798(transcript)|refseq:NP_780561.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RNrf9mOVy5IHiHQO4D+oOJ3b+cY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3V0J1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986682|ensembl:ENSMUSP00000139823|uniprotkb:B2RVK7|uniprotkb:Q3TIS2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tm237_mouse(display_long)|uniprotkb:Tmem237(gene name)|psi-mi:Tmem237(display_short)|uniprotkb:Als2cr4(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000038079(gene)|ensembl:ENSMUST00000186794(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060271"(cilium assembly)|go:"GO:0120199"(cone photoreceptor outer segment)|go:"GO:0120200"(rod photoreceptor outer segment)|interpro:IPR029409|refseq:NP_001028621.1|refseq:NP_001032901.1|ensembl:ENSMUSG00000038079 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AK5L+5IVoyvXYOk1rsDw5M8p+Io10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3UZ28 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986879 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3uz28_mouse(display_long)|uniprotkb:Acin1(gene name)|psi-mi:Acin1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WS203ieVfNVCvkl7KZJ4aauo+VY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TL33 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986840 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tl33_mouse(display_long)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR027239|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:J9M3yXdRMrlvNECRnTFWC0d43Sk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C407 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2552173|ensembl:ENSMUSP00000024873|uniprotkb:Q99KZ9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:yipf4_mouse(display_long)|uniprotkb:Yipf4(gene name)|psi-mi:Yipf4(display_short)|uniprotkb:YIP1 family member 4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000024072(gene)|ensembl:ENSMUST00000024873(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|refseq:NP_080693.2|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006977(Yip1 domain)|go:"GO:0005886"(plasma membrane) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:TR4qIEHnxmKzv/OYbTdYLjPUv/E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D4P0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986888|ensembl:ENSMUSP00000069725|uniprotkb:Q8BFU5 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arl5b_mouse(display_long)|uniprotkb:Arl5b(gene name)|psi-mi:Arl5b(display_short)|uniprotkb:Arl8(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 8(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|go:"GO:1903292"(protein localization to Golgi membrane)|ensembl:ENSMUSG00000017418(gene)|ensembl:ENSMUST00000069870(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|refseq:NP_083742.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:xRuUCUSSlU08fn0izyhAOcUwffY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P48453 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-642618|uniprotkb:Q6NZR4|ensembl:ENSMUSP00000125722 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pp2bb_mouse(display_long)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Ppp3cb(gene name)|psi-mi:Ppp3cb(display_short)|uniprotkb:Calnb(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032940.1|refseq:NP_001297355.1|refseq:NP_001297356.1|ensembl:ENSMUSG00000021816(gene)|ensembl:ENSMUST00000159027(transcript)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034097"(response to cytokine)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P48453|reactome:R-MMU-2025928|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-5607763|go:"GO:0005516"(calmodulin binding) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:YD7q3dcL87htgwHRd5m5ReMlqd010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9ESX4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987119|ensembl:ENSMUSP00000120807 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:no40_mouse(display_long)|uniprotkb:Zcchc17(gene name)|psi-mi:Zcchc17(display_short)|uniprotkb:Ps1d(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Ldc4(orf name) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUST00000134159(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|ensembl:ENSMUSG00000028772(gene)|refseq:NP_694800.1|refseq:XP_006503322.1|refseq:XP_006503323.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:K24HiVASvlaM8g4AI+iQ76f8jhc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99M08 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986903|ensembl:ENSMUSP00000102037|uniprotkb:Q8CEY1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cd003_mouse(display_long) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000054091(gene)|ensembl:ENSMUST00000106429(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR038780|refseq:NP_077781.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:O/Nzw0isr+13/NAhFPKICGduv+w10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70296 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1634763|uniprotkb:Q9D8G9|uniprotkb:Q9JJ58|ensembl:ENSMUSP00000048425 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pebp1_mouse(display_long)|uniprotkb:Pebp1(gene name)|psi-mi:Pebp1(display_short)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pebp(gene name synonym)|uniprotkb:HCNPpp(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_061346.2|ensembl:ENSMUSG00000032959(gene)|ensembl:ENSMUST00000036951(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043679"(axon terminus)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045177"(apical part of cell)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060409"(positive regulation of acetylcholine metabolic process)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P70296|rcsb pdb:6ENS|reactome:R-MMU-5674135|reactome:R-MMU-5675221 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vhkkuZ49z3Vuw7O4bdlc/5WxlKk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q5EBG4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987708 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q5ebg4_mouse(display_long)|uniprotkb:Nsmce4a(gene name)|psi-mi:Nsmce4a(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR027786|interpro:IPR014854(Nse4) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:f+PzCB7Ha5orhC/GSxM1MUPZyQc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TYK4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987718 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tyk4_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005886"(plasma membrane)|go:"GO:0030552"(cAMP binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:XP_006532572.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jCZTRD9RmEMm9kQHJ16s1UQNqSw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C9V6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987698 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q8c9v6_mouse(display_long)|uniprotkb:Mpdu1(gene name)|psi-mi:Mpdu1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0016021"(integral component of membrane)|interpro:IPR016817(Mannose-P-dolichol utilization defect 1 protein)|interpro:IPR006603(Cystinosin/ERS1p repeat) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qwMsMpx5rKd06nX6rkyFaNlnhks10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q61234 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0R4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987768|ensembl:ENSMUSP00000004507 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ddx56_mouse(display_long)|uniprotkb:Ddx56(gene name)|psi-mi:Ddx56(display_short)|uniprotkb:D11Ertd619e(gene name synonym)|uniprotkb:Noh61(gene name synonym)|uniprotkb:ATP-dependent 61 kDa nucleolar RNA helicase(gene name synonym)|uniprotkb:DEAD box protein 56(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0006364"(rRNA processing)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0005730"(nucleolus)|ensembl:ENSMUSG00000004393(gene)|ensembl:ENSMUST00000004507(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_080814.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ApoMFgf+5gF9JsAuHKAoVMhUuWI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D198 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987953|ensembl:ENSMUSP00000030622 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:syf2_mouse(display_long)|uniprotkb:Syf2(gene name)|psi-mi:Syf2(display_short)|uniprotkb:Cbpin(gene name synonym)|uniprotkb:Gcipip(gene name synonym)|uniprotkb:CCNDBP1-interactor(gene name synonym)|uniprotkb:mp29(gene name synonym)|uniprotkb:p29(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000028821(gene)|ensembl:ENSMUST00000030622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0048568"(embryonic organ development)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR013260(mRNA splicing factor SYF2)|reactome:R-MMU-72163|go:"GO:0005634"(nucleus)|refseq:NP_081056.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6hFH1DWkMC+jlbtEApKhgZdhbNw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q505F5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2255533|uniprotkb:Q3U380|uniprotkb:Q6ZPW2|uniprotkb:Q9CUZ0|ensembl:ENSMUSP00000030894 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:lrc47_mouse(display_long)|uniprotkb:Kiaa1185(gene name synonym)|uniprotkb:Lrrc47(gene name)|psi-mi:Lrrc47(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_957678.1|ensembl:ENSMUSG00000029028(gene)|ensembl:ENSMUST00000030894(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR020825|interpro:IPR032675|mint:Q505F5 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:rPKKMiAYd+Dtcvc0CJAMiCDhF/E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QUM9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-991694|uniprotkb:Q0VGS3|uniprotkb:Q3TT07|uniprotkb:Q3U6Y2|ensembl:ENSMUSP00000021412 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psa6_mouse(display_long)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:Psma6(gene name)|psi-mi:Psma6(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_036098.1|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:Q9QUM9|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|ensembl:ENSMUSG00000021024(gene)|ensembl:ENSMUST00000021412(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|reactome:R-MMU-69481|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:VgUJoxRfxHDdUz0LNg/kcEY95a010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C5Q4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987747|ensembl:ENSMUSP00000077972|uniprotkb:Q8BR05|uniprotkb:Q8BRG7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:grsf1_mouse(display_long)|uniprotkb:Grsf1(gene name)|psi-mi:Grsf1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000044221(gene)|ensembl:ENSMUST00000078945(transcript)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033106|interpro:IPR034424|interpro:IPR034425|interpro:IPR034426|interpro:IPR035979|refseq:NP_001091946.1|refseq:NP_848815.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:TtINkS9ItSNkMkEI4miiflAPuH010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CR46 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987825|ensembl:ENSMUSP00000020794|uniprotkb:B2KGY1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ska2_mouse(display_long)|uniprotkb:Ska2(gene name)|psi-mi:Ska2(display_short)|uniprotkb:Fam33a(gene name synonym)|uniprotkb:Protein FAM33A(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000020492(gene)|ensembl:ENSMUST00000020794(transcript)|reactome:R-MMU-2467813|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005737"(cytoplasm)|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|reactome:R-MMU-9648025|go:"GO:0008017"(microtubule binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|interpro:IPR026762|interpro:IPR042091|reactome:R-MMU-141444|refseq:NP_079653.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:kKAV000kzn0aogtAaoQiQQseTqU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DCR2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9085419|uniprotkb:O88670|ensembl:ENSMUSP00000025357 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ap3s1_mouse(display_long)|uniprotkb:Ap3s1(gene name)|psi-mi:Ap3s1(display_short)|uniprotkb:AP-3 complex subunit sigma-3A(gene name synonym)|uniprotkb:Sigma-3A-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3a(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit sigma-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033811.1|ensembl:ENSMUSG00000024480(gene)|ensembl:ENSMUST00000025357(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027155|reactome:R-MMU-432722|go:"GO:0048490"(anterograde synaptic vesicle transport) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:fRNNY4ETqt4Qv6CTQqFxeIk8Syc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TVR4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987976 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tvr4_mouse(display_long)|uniprotkb:Ldlr(gene name)|psi-mi:Ldlr(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR018097|interpro:IPR009030(Growth factor, receptor)|interpro:IPR023415|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR036055 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:zkrY5x4nVniabgG8BtEsLFTcTqg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:B7U582 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987634 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:b7u582_mouse(display_long) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005524"(ATP binding)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Uof+8twOsAo3Nbmiz+3dmBAbZuY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P49615 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6510052|ensembl:ENSMUSP00000030814 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cdk5_mouse(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:Cdkn5(gene name synonym)|uniprotkb:Crk6(gene name synonym)|uniprotkb:CR6 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000028969(gene)|ensembl:ENSMUST00000030814(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070509"(calcium ion import)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099533"(positive regulation of presynaptic cytosolic calcium concentration)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49615|reactome:R-MMU-180024|reactome:R-MMU-399956|reactome:R-MMU-6804756|refseq:NP_031694.1|dip:DIP-29353N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:mFzCd7zhLyXpxPDQwc1xXCraDQI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P26443 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-773329|uniprotkb:Q8C273|ensembl:ENSMUSP00000022322 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dhe3_mouse(display_long)|uniprotkb:Glud1(gene name)|psi-mi:Glud1(display_short)|uniprotkb:Glud(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_032159.1|ensembl:ENSMUSG00000021794(gene)|ensembl:ENSMUST00000022322(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0007616"(long-term memory)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P26443|reactome:R-MMU-2151201|reactome:R-MMU-8964539 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:HbPeUm/tpMD6GrgM/863swTQqGA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P35922 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-645094 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:fmr1_mouse(display_long)|uniprotkb:Fmr1(gene name)|psi-mi:Fmr1(display_short)|uniprotkb:Fmr-1(gene name synonym)|uniprotkb:Fragile X mental retardation protein 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032196|interpro:IPR040472|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0003723"(RNA binding)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0097444"(spine apparatus)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990812"(growth cone filopodium)|go:"GO:0044297"(cell body)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|mint:P35922|interpro:IPR036612|interpro:IPR040148|interpro:IPR041560 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:/NR92KtQt5zwsa+U6lel3sXQyu810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BU88 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987847|ensembl:ENSMUSP00000020820|uniprotkb:Q8BK04 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rm22_mouse(display_long)|uniprotkb:Mrpl22(gene name)|psi-mi:Mrpl22(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000020514(gene)|ensembl:ENSMUST00000020820(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|interpro:IPR036394|reactome:R-MMU-5389840|reactome:R-MMU-5419276|refseq:NP_778166.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:cRxs2SM4w9kZbs7KkelNNMDhlVM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DCC4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-309124|uniprotkb:Q8R0P9|uniprotkb:Q9D0X2|ensembl:ENSMUSP00000049605 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:p5cr3_mouse(display_long)|uniprotkb:Pycr3(gene name)|psi-mi:Pycr3(display_short)|uniprotkb:Pycrl(gene name synonym)|uniprotkb:Pyrroline-5-carboxylate reductase-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079688.2|mint:Q9DCC4|reactome:R-MMU-8964539|interpro:IPR036291|ensembl:ENSMUST00000053918(transcript)|ensembl:ENSMUSG00000022571(gene)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009972"(cytidine deamination)|go:"GO:0045171"(intercellular bridge)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jFHIXiwsk2+9150Lf5CYemK6hWs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O35465 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987880|ensembl:ENSMUSP00000112527|uniprotkb:Q3UK86|uniprotkb:Q6GTX9|uniprotkb:Q811M7|uniprotkb:Q811R4|uniprotkb:Q8C2F0|uniprotkb:Q99L93 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:fkbp8_mouse(display_long)|uniprotkb:Fkbp8(gene name)|psi-mi:Fkbp8(display_short)|uniprotkb:Fkbp38(gene name synonym)|uniprotkb:Sam11(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_017168056.1|refseq:XP_017168057.1|ensembl:ENSMUSG00000019428(gene)|ensembl:ENSMUST00000119353(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021915"(neural tube development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-MMU-5689880|go:"GO:0006457"(protein folding)|refseq:NP_001104536.1|refseq:NP_001186560.1|refseq:NP_034353.2|refseq:XP_006509619.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:GDqutaROJ92KpoVvNBAzSEIlW/I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D1E8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-773051|uniprotkb:Q3U702|uniprotkb:Q8BG61|uniprotkb:Q8CGN6|ensembl:ENSMUSP00000117025 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:plce_mouse(display_long)|uniprotkb:Lysophosphatidic acid acyltransferase epsilon(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 5(gene name synonym)|uniprotkb:Agpat5(gene name)|psi-mi:Agpat5(display_short)|uniprotkb:D8Ertd319e(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_081068.1|ensembl:ENSMUSG00000031467(gene)|ensembl:ENSMUST00000149565(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006639"(acylglycerol metabolic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016746"(acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|reactome:R-MMU-1483166 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:X41ziBW1Ze8pBtOr/MeUhg/fezA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P81269 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987643|ensembl:ENSMUSP00000023769 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:atf1_mouse(display_long)|uniprotkb:Atf1(gene name)|psi-mi:Atf1(display_short)|uniprotkb:Activating transcription factor 1(gene name synonym)|uniprotkb:TCR-ATF1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0032025"(response to cobalt ion)|go:"GO:0034622"|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029825|reactome:R-MMU-199920|go:"GO:0014070"(response to organic cyclic compound)|ensembl:ENSMUSG00000023027(gene)|ensembl:ENSMUST00000023769(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010976"(positive regulation of neuron projection development)|refseq:NP_031523.3|refseq:XP_006520414.1|refseq:XP_006520415.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:cKn7HUUvwbjeBrX7Q4aQSTR5inE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DC69 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-772731|intact:EBI-2934552|uniprotkb:Q6GTD3|uniprotkb:Q99JP9|ensembl:ENSMUSP00000144904 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ndua9_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:Ndufa9(gene name)|psi-mi:Ndufa9(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079634.2|ensembl:ENSMUSG00000000399(gene)|ensembl:ENSMUST00000205002(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR008030(NmrA-like)|interpro:IPR036291|mint:Q9DC69|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:cyWl9Af7lg/hJx/mANKhMVV4jbQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z1X9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4286086|uniprotkb:O70547|uniprotkb:Q9QUK1|uniprotkb:Q9R212|ensembl:ENSMUSP00000000028 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cdc45_mouse(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:Cdc45l(gene name synonym)|uniprotkb:Cdc45l2(gene name synonym)|uniprotkb:PORC-PI-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033992.2|refseq:XP_011244115.1|refseq:XP_006521807.1|ensembl:ENSMUST00000000028(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0036064"(ciliary basal body)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|reactome:R-MMU-176187|reactome:R-MMU-68962|ensembl:ENSMUSG00000000028(gene) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Wzhe8ySAL7uFlRNFWgU3lbhJLVc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R1J3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987628 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q9r1j3_mouse(display_long) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0003723"(RNA binding)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RuD713eZFbckrlMSvjlqn+8b1Fg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6A0A2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987790|ensembl:ENSMUSP00000140993|uniprotkb:Q3TUH7|uniprotkb:Q6AZA8|uniprotkb:Q8BJP3|uniprotkb:Q8BY17 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:lar4b_mouse(display_long)|uniprotkb:Larp4b(gene name)|psi-mi:Larp4b(display_short)|uniprotkb:D13Wsu64e(gene name synonym)|uniprotkb:Kiaa0217(gene name synonym)|uniprotkb:Larp5(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001298046.1|ensembl:ENSMUSG00000033499(gene)|ensembl:ENSMUST00000188211(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|refseq:NP_766173.1|refseq:XP_006516539.1|refseq:XP_006516540.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ApbenASAKU1pHcJSDiRwmczYTUM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CFV4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987863|ensembl:ENSMUSP00000040900|uniprotkb:Q7TSR9 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nrn1_mouse(display_long)|uniprotkb:Nrn1(gene name)|psi-mi:Nrn1(display_short)|uniprotkb:Cpg15(gene name synonym)|uniprotkb:Candidate plasticity gene 15 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000039114(gene)|ensembl:ENSMUST00000037623(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR026144|reactome:R-MMU-163125|go:"GO:0098978"(glutamatergic synapse)|refseq:NP_705757.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:J2WOhg7GyXb3dyUC4R5cAh6Eaos10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8K0H5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-5744209|uniprotkb:Q8C8H2|uniprotkb:Q9QYY5|ensembl:ENSMUSP00000118105 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:taf10_mouse(display_long)|uniprotkb:Taf10(gene name)|psi-mi:Taf10(display_short)|uniprotkb:Taf2h(gene name synonym)|uniprotkb:Tafii30(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 30 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_064408.2|dip:DIP-59890N|ensembl:ENSMUSG00000043866(gene)|ensembl:ENSMUST00000141116(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000125"|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0034622"|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|mint:Q8K0H5|reactome:R-MMU-5689880|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:dpcFKIlnQhWZ8SpD8HJ4uFowyYY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O35280 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2553137|uniprotkb:O54925|uniprotkb:Q8CI40|uniprotkb:Q9D0N2|ensembl:ENSMUSP00000034625|ensembl:ENSMUSP00000134388 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:chk1_mouse(display_long)|uniprotkb:Chk1(gene name synonym)|uniprotkb:Chek1(gene name)|psi-mi:Chek1(display_short)|uniprotkb:CHK1 checkpoint homolog(gene name synonym)|uniprotkb:Checkpoint kinase-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048096"|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034670|reactome:R-MMU-1433557|reactome:R-MMU-176187|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|reactome:R-MMU-69601|reactome:R-MMU-8953750|ensembl:ENSMUSG00000032113(gene)|ensembl:ENSMUST00000034625(transcript)|ensembl:ENSMUST00000172702(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006997"(nucleus organization)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010767"(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035402"("histone kinase activity (H3-T11 specific)")|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_031717.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:AozTzir+BE8FDAvmLniUHEuFQLI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9ER69 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987670|uniprotkb:Q3U120|uniprotkb:Q566J5 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:fl2d_mouse(display_long)|uniprotkb:Wtap(gene name)|psi-mi:Wtap(display_short)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 reactome:R-MMU-72203|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|go:"GO:0005634"(nucleus)|refseq:NP_001107004.1|refseq:NP_780603.1|dip:DIP-58948N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:A27nq9H9lYiBtNAx7ijBAfVSJVM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80ZJ1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-397246|uniprotkb:Q3USK1|uniprotkb:Q7TSK4|uniprotkb:Q810A2|uniprotkb:Q9D3D5|ensembl:ENSMUSP00000056433 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rap2a_mouse(display_long)|uniprotkb:Rap2a(gene name)|psi-mi:Rap2a(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_083795.2|ensembl:ENSMUSG00000051615(gene)|ensembl:ENSMUST00000062117(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035690"|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|go:"GO:0048814"(regulation of dendrite morphogenesis) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:LH08P2tTzdf9ZmkH6UZ+X84ZEXI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P63024 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2311664|uniprotkb:Q3TH70|uniprotkb:Q64271|ensembl:ENSMUSP00000030797 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:vamp3_mouse(display_long)|uniprotkb:Vamp3(gene name)|psi-mi:Vamp3(display_short)|uniprotkb:Syb3(gene name synonym)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033524.1|ensembl:ENSMUSG00000028955(gene)|ensembl:ENSMUST00000030797(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63024|reactome:R-MMU-1236974|reactome:R-MMU-6811440|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+bFr3sWwXWDPrsL8ZRrf+4CpLqo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VHZ7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987370|ensembl:ENSMUSP00000027303|uniprotkb:Q3U8H6|uniprotkb:Q8CI42|uniprotkb:Q9CWN6|uniprotkb:Q9CYT5 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:imp4_mouse(display_long)|uniprotkb:Imp4(gene name)|psi-mi:Imp4(display_short)|uniprotkb:D1Wsu40e(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000026127(gene)|ensembl:ENSMUST00000027303(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281|reactome:R-MMU-6791226|refseq:NP_848716.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1WVa0s6Mv6Dz1b25/GhNRnbI2ts10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P12815 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-309164|uniprotkb:Q545I0|uniprotkb:Q61145|ensembl:ENSMUSP00000022060|intact:EBI-6896040 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pdcd6_mouse(display_long)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:PMP41(gene name synonym)|uniprotkb:ALG-257(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_035181.1|refseq:XP_006517219.1|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1HQV|rcsb pdb:5JJG - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D0J4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1033319|uniprotkb:Q9WUM1|ensembl:ENSMUSP00000025893 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:arl2_mouse(display_long)|uniprotkb:Arl2(gene name)|psi-mi:Arl2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062696.2|ensembl:ENSMUSG00000024944(gene)|ensembl:ENSMUST00000025893(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:4GOK|reactome:R-MMU-83936|reactome:R-MMU-9648002|dip:DIP-36659N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:zb6s8gL3Fr5kyys6iB/rrgsj7qI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6ZPE9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987390 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q6zpe9_mouse(display_long)|uniprotkb:Scaf11(gene name)|psi-mi:Scaf11(display_short)|uniprotkb:mKIAA3013(gene name synonym)|uniprotkb:Sfrs2ip(gene name synonym)|uniprotkb:Srsf2ip(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0046872"(metal ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_082424.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+N6m+GCg28lVasgf09BZmLDO05I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q68FG8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987336 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q68fg8_mouse(display_long)|uniprotkb:Ttc13(gene name)|psi-mi:Ttc13(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:g0sWdr+o2813Dyt/ltcTxoIz/XU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:A6H663 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987195 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:a6h663_mouse(display_long)|uniprotkb:Bag3(gene name)|psi-mi:Bag3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0051087"(chaperone binding)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:xdE25m8ClXN+W57r6hTmYtW7JEs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8C7V3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987349|ensembl:ENSMUSP00000048204|uniprotkb:Q3TRG8|uniprotkb:Q8K231 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:utp15_mouse(display_long)|uniprotkb:Utp15(gene name)|psi-mi:Utp15(display_short)|uniprotkb:Src-associated protein SAW(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000041747(gene)|ensembl:ENSMUST00000040972(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|reactome:R-MMU-6791226|refseq:NP_849249.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:O4nUXO8gj/S7z/c8ZF3lCQJH87s10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3U0V2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1544032|ensembl:ENSMUSP00000034359 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tradd_mouse(display_long)|uniprotkb:Tradd(gene name)|psi-mi:Tradd(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001028333.1|dip:DIP-38039N|ensembl:ENSMUSG00000031887(gene)|ensembl:ENSMUST00000034359(transcript)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0070513"(death domain binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5675482|reactome:R-MMU-69416|reactome:R-MMU-75893 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:mlpT7wj+kR184H5CFZnqmlPz52810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q921E6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BH15 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987555|ensembl:ENSMUSP00000064840|uniprotkb:Q05CH8|uniprotkb:Q3TSS4|uniprotkb:Q3UDS5|uniprotkb:Q80VN2|uniprotkb:Q8CI74 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cno10_mouse(display_long)|uniprotkb:Cnot10(gene name)|psi-mi:Cnot10(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000056167(gene)|ensembl:ENSMUST00000070117(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019734|interpro:IPR039740|reactome:R-MMU-429947|reactome:R-MMU-6804115|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_705813.2|refseq:XP_006512462.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:uDIpYpZA4Tc2EQUy34V3aO+Ywgk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P31230 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4285838|uniprotkb:Q60659|ensembl:ENSMUSP00000142513 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:aimp1_mouse(display_long)|uniprotkb:Aimp1(gene name)|psi-mi:Aimp1(display_short)|uniprotkb:Emap2(gene name synonym)|uniprotkb:Scye1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000028029(gene)|ensembl:ENSMUST00000198513(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P31230 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:8fzNg74uhnuVkm2zNOuQMTIIjVc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q921N6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987470|ensembl:ENSMUSP00000018143|uniprotkb:Q3UUG2|uniprotkb:Q8R0W3|uniprotkb:Q8R1E2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ddx27_mouse(display_long)|uniprotkb:Ddx27(gene name)|psi-mi:Ddx27(display_short)|uniprotkb:DEAD box protein 27(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000017999(gene)|ensembl:ENSMUST00000018143(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_694705.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:GKgBlVkBMY67clheQ3r0MYPCAP410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q7TQH0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6908203|ensembl:ENSMUSP00000035415|uniprotkb:Q80XN9|uniprotkb:Q8K059 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:atx2l_mouse(display_long)|uniprotkb:Atxn2l(gene name)|psi-mi:Atxn2l(display_short)|uniprotkb:A2lp(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_006507788.1|ensembl:ENSMUSG00000032637(gene)|ensembl:ENSMUST00000040202(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q7TQH0|refseq:NP_898841.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7v7iuPRti2err2QrmJIGoWqEM3U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q04447 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1634233|uniprotkb:Q3KQP4|uniprotkb:Q3TKI3|uniprotkb:Q3U5P5|uniprotkb:Q3UF71|uniprotkb:Q9CXK6|ensembl:ENSMUSP00000001304 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:kcrb_mouse(display_long)|uniprotkb:Ckb(gene name)|psi-mi:Ckb(display_short)|uniprotkb:Ckbb(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:B-CK(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_067248.1|ensembl:ENSMUSG00000001270(gene)|ensembl:ENSMUST00000001304(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q04447|reactome:R-MMU-71288|reactome:R-MMU-9696264 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7r2Owq3p9g124vCs/sG4m8aScuU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91VI7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4285005|uniprotkb:Q924P4|ensembl:ENSMUSP00000101651|ensembl:ENSMUSP00000133061 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rini_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Rnh(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001165571.1|refseq:NP_001165572.1|refseq:NP_660117.2|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR041302|mint:Q91VI7|rcsb pdb:3TSR|ensembl:ENSMUSG00000038650(gene)|ensembl:ENSMUST00000106033(transcript)|ensembl:ENSMUST00000167493(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:22sdTjNahBoEuq/md/5/amFIPeM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6PAC3 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987447|ensembl:ENSMUSP00000022909|uniprotkb:E9QPL0 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dca13_mouse(display_long)|uniprotkb:Dcaf13(gene name)|psi-mi:Dcaf13(display_short)|uniprotkb:Gm83(gene name synonym)|uniprotkb:Wdsof1(gene name synonym)|uniprotkb:WD repeat and SOF domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000022300(gene)|ensembl:ENSMUST00000022909(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030054"(cell junction)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-MMU-6791226|reactome:R-MMU-8951664|refseq:NP_941008.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:JjCYdroTM6O1OOli/RZchk23S1010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q62432 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2337932|uniprotkb:Q6GU18|uniprotkb:Q6VP00|uniprotkb:Q9D8P6|ensembl:ENSMUSP00000025453|ensembl:ENSMUSP00000130115 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:smad2_mouse(display_long)|uniprotkb:Smad2(gene name)|psi-mi:Smad2(display_short)|uniprotkb:Madh2(gene name synonym)|uniprotkb:Madr2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_034884.2|refseq:NP_001239410.1|refseq:NP_001297999.1|refseq:XP_006525762.1|refseq:XP_017173331.1|ensembl:ENSMUSG00000024563(gene)|ensembl:ENSMUST00000025453(transcript)|ensembl:ENSMUST00000168423(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0007389"(pattern specification process)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q62432|reactome:R-MMU-1181150|reactome:R-MMU-1502540|reactome:R-MMU-2173788|reactome:R-MMU-2173789|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-5689880|reactome:R-MMU-9617828 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:PDNrM3U7qpRcHjSJIPv50FD2W7E10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BHC7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987297|ensembl:ENSMUSP00000027322|ensembl:ENSMUSP00000137770|uniprotkb:Q99K13|uniprotkb:Q9D5L8 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rhbl4_mouse(display_long)|uniprotkb:Rhbdd1(gene name)|psi-mi:Rhbdd1(display_short)|uniprotkb:Rhbdl4(gene name synonym)|uniprotkb:Rhomboid domain-containing protein 1(gene name synonym)|uniprotkb:Rhomboid-like protein 4(gene name synonym)|uniprotkb:MSD-50(orf name)|uniprotkb:MSD50(orf name) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000026142(gene)|ensembl:ENSMUST00000027322(transcript)|ensembl:ENSMUST00000140020(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1904211"(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR022764|interpro:IPR035952|go:"GO:0051047"(positive regulation of secretion)|refseq:NP_001116157.1|refseq:NP_084053.3|refseq:XP_006496637.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Tks/8e+4C98lsnK9509X0gcq3Sk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q99JI4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-992120|uniprotkb:Q9CWZ1|ensembl:ENSMUSP00000022256 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psmd6_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Psmd6(gene name)|psi-mi:Psmd6(display_short)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_079826.2|ensembl:ENSMUSG00000021737(gene)|ensembl:ENSMUST00000022256(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-983168 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:7n3IJIpvsL7lkD/Io01YJOINOYk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R472 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987403|ensembl:ENSMUSP00000150629 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q8r472_mouse(display_long)|uniprotkb:Higd1a(gene name)|psi-mi:Higd1a(display_short)|uniprotkb:Hig1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000038412(gene)|ensembl:ENSMUST00000215007(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR007667(Hypoxia induced protein conserved region) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WFP1M+ZjnxlKggFZ3I8Pp0ZtmCo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BX57 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987209|ensembl:ENSMUSP00000152987|uniprotkb:Q3TD60|uniprotkb:Q3TEL7|uniprotkb:Q3TZZ1|uniprotkb:Q3U197|uniprotkb:Q3U773|uniprotkb:Q3UCS5|uniprotkb:Q4FBH7|uniprotkb:Q91WB6 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:pxk_mouse(display_long)|uniprotkb:Pxk(gene name)|psi-mi:Pxk(display_short)|uniprotkb:Modulator of Na,K-ATPase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000033885(gene)|ensembl:ENSMUST00000225653(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0050804"(modulation of chemical synaptic transmission)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001683(Phox-like)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036871|interpro:IPR037903|go:"GO:0004672"(protein kinase activity)|refseq:NP_663433.2|refseq:NP_840063.1|refseq:XP_006518042.1|refseq:XP_006518039.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jzk3dPsF8Xb3gv6GwWBt9OhwMbI10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6NX79 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987343 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q6nx79_mouse(display_long)|uniprotkb:Nkapd1(gene name)|psi-mi:Nkapd1(display_short)|uniprotkb:AU019823(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR043407|go:"GO:0042802"(identical protein binding)|refseq:NP_001128374.1|refseq:NP_997614.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:YobULKqig+DZgf0xrgAOuFCjtFg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q91WE6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987248|ensembl:ENSMUSP00000006353|uniprotkb:Q3TE97|uniprotkb:Q3V3D2|uniprotkb:Q5T0I5|uniprotkb:Q8C4B0|uniprotkb:Q9CT69 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cdkal_mouse(display_long)|uniprotkb:Cdkal1(gene name)|psi-mi:Cdkal1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001295415.1|ensembl:ENSMUSG00000006191(gene)|ensembl:ENSMUST00000006353(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|refseq:NP_653119.1|ensembl:ENSMUSG00000006191|ensembl:ENSMUSG00000006191 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:IisXNJTgasYKR88DtZ1BtS7ghGw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R5K4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987532|ensembl:ENSMUSP00000030138|uniprotkb:Q3TL75|uniprotkb:Q3U1P8|uniprotkb:Q6PAN8|uniprotkb:Q8C6V4|uniprotkb:Q8R5K3|uniprotkb:Q8VCG0|uniprotkb:Q8WTY7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nol6_mouse(display_long)|uniprotkb:Nol6(gene name)|psi-mi:Nol6(display_short)|uniprotkb:Nucleolar RNA-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0034456"(UTP-C complex)|interpro:IPR005554(Nrap protein)|interpro:IPR035082|interpro:IPR035367|interpro:IPR035368|interpro:IPR035369|interpro:IPR035370|interpro:IPR035371|reactome:R-MMU-6791226|go:"GO:0032545"(CURI complex)|ensembl:ENSMUSG00000028430(gene)|ensembl:ENSMUST00000030138(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0032040"(small-subunit processome)|refseq:NP_631982.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:+O2s4fz3vJ+ZL8vjj6H9F3S0nlk10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q80X32 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987289|ensembl:ENSMUSP00000055271|uniprotkb:Q8C2G2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ce024_mouse(display_long) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000045767(gene)|ensembl:ENSMUST00000057844(transcript)|interpro:IPR040419|refseq:NP_851795.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pU0JffCEU2kHSFpVJkK9LshzyAc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R0F5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987417|ensembl:ENSMUSP00000033433|uniprotkb:A2AF74|uniprotkb:Q3TI42 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rbmx2_mouse(display_long)|uniprotkb:Rbmx2(gene name)|psi-mi:Rbmx2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000031107(gene)|ensembl:ENSMUST00000033433(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0071011"(precatalytic spliceosome)|refseq:NP_775552.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:v1YvKqUmxA+WNBMfY/5wAuPummg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9JLQ0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:B7ZCT1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987495|ensembl:ENSMUSP00000104408 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:b7zct1_mouse(display_long)|uniprotkb:Rgs19(gene name)|psi-mi:Rgs19(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000002458(gene)|ensembl:ENSMUST00000108778(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005903"(brush border)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|refseq:NP_001278134.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:r97NjToLHVZIfSGVhhNM9mzf36810090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q61316 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2013169 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:hsp74_mouse(display_long)|uniprotkb:Hspa4(gene name)|psi-mi:Hspa4(display_short)|uniprotkb:Apg2(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 dip:DIP-46965N|mint:Q61316|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|reactome:R-MMU-3371453 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:LEZQFUhx6IFE7HTuGpJQ9TQLL9Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CPZ6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987431|ensembl:ENSMUSP00000053056|uniprotkb:A2A4X7|uniprotkb:Q8BN65|uniprotkb:Q8R0U5 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:orml3_mouse(display_long)|uniprotkb:Ormdl3(gene name)|psi-mi:Ormdl3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000038150(gene)|ensembl:ENSMUST00000052919(transcript)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042552"(myelination)|go:"GO:0061744"(motor behavior)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904221"(negative regulation of serine C-palmitoyltransferase activity)|go:"GO:2000303"(regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-MMU-1660661|reactome:R-MMU-6798695|interpro:IPR029883|refseq:NP_079937.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:UkCPo4UOqyKioN5vHFl+0l5yuNs10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q571G4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-2553427|ensembl:ENSMUSP00000159391|ensembl:ENSMUSP00000159392|uniprotkb:Q8BMU8|uniprotkb:Q8C107|uniprotkb:Q3UYW5|uniprotkb:Q3KQN0|uniprotkb:A0JLY2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:lin54_mouse(display_long)|uniprotkb:Kiaa2037(gene name synonym)|uniprotkb:Lin54(gene name)|psi-mi:Lin54(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000118665(gene)|ensembl:ENSMUST00000239512(transcript)|ensembl:ENSMUST00000239513(transcript)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0046872"(metal ion binding)|interpro:IPR005172(Tesmin/TSO1-like, CXC)|interpro:IPR028307|interpro:IPR033467|reactome:R-MMU-1538133|refseq:NP_001108482.1|refseq:NP_766302.2|refseq:XP_006534947.1|refseq:XP_006534949.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:e5Cmqo8YxFtVyqhBNYqYnWEIfyA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q6IWE2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987511 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q6iwe2_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR004000(Actin/actin-like)|interpro:IPR043129 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:llV9FgSw+Y+cqokULSqfoc4Yeeg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P28229 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1767271|ensembl:ENSMUSP00000066901|ensembl:ENSMUSP00000090228|ensembl:ENSMUSP00000102690 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cxg1_mouse(display_long)|uniprotkb:Gjc1(gene name)|psi-mi:Gjc1(display_short)|uniprotkb:Cxn-45(gene name synonym)|uniprotkb:Gja7(gene name synonym)|uniprotkb:Gap junction alpha-7 protein(gene name synonym)|uniprotkb:Connexin-45(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_011247038.1|refseq:NP_001152854.1|refseq:NP_001152855.1|refseq:NP_032148.1|refseq:XP_006532289.1|refseq:XP_006532290.1|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0045202"(synapse)|go:"GO:0048468"(cell development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0086053"(AV node cell to bundle of His cell communication by electrical coupling)|go:"GO:0086077"(gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling)|interpro:IPR000500(Connexins)|interpro:IPR002265("Gap junction alpha-6 protein (Cx45)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR017990|interpro:IPR019570|interpro:IPR038359|reactome:R-MMU-112303|reactome:R-MMU-190861|ensembl:ENSMUSG00000034520(gene)|ensembl:ENSMUST00000068933(transcript)|ensembl:ENSMUST00000092567(transcript)|ensembl:ENSMUST00000107075(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005216"(ion channel activity)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007268"(chemical synaptic transmission) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Nhhg8t9MCvbOYs/G8HU7FqLNrK010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CYN2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986662|ensembl:ENSMUSP00000041152|uniprotkb:Q3THR2|uniprotkb:Q80X74|uniprotkb:Q921V8|uniprotkb:Q9CXK1 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:spcs2_mouse(display_long)|uniprotkb:Spcs2(gene name)|psi-mi:Spcs2(display_short)|uniprotkb:Spc25(gene name synonym)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000035227(gene)|ensembl:ENSMUST00000036274(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|reactome:R-MMU-422085|go:"GO:0008233"(peptidase activity)|refseq:NP_079944.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:BHBLRGlAPfTdC3uidNr0no/BeeA10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VCG1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986975|ensembl:ENSMUSP00000080767 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q8vcg1_mouse(display_long)|uniprotkb:Dut(gene name)|psi-mi:Dut(display_short)|uniprotkb:Dutp(gene name synonym)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000027203(gene)|ensembl:ENSMUST00000082122(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0030547"(signaling receptor inhibitor activity)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0046081"(dUTP catabolic process)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|reactome:R-MMU-499943|refseq:NP_001153118.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:tDnetWxEsdzlqgqMsfKMB2bIPVY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O88379 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-927567|uniprotkb:Q3UXF6|uniprotkb:Q3TKK7|ensembl:ENSMUSP00000039757 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:baz1a_mouse(display_long)|uniprotkb:Baz1a(gene name)|psi-mi:Baz1a(display_short)|uniprotkb:Cbp146(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000035021(gene)|ensembl:ENSMUST00000038926(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008623"(CHRAC)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037325 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:85cMCsyUhSWjufEUpATshF/rq+w10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P62274 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987039|ensembl:ENSMUSP00000038352|uniprotkb:P30054 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rs29_mouse(display_long)|uniprotkb:Rps29(gene name)|psi-mi:Rps29(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000034892(gene)|ensembl:ENSMUST00000037023(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_033119.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:vMgvFs6gwidbpv837yH2u0sSIAU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QXY6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-775304|uniprotkb:Q8K590|ensembl:ENSMUSP00000024860 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ehd3_mouse(display_long)|uniprotkb:Ehd3(gene name)|psi-mi:Ehd3(display_short)|uniprotkb:Ehd2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_065603.2|ensembl:ENSMUSG00000024065(gene)|ensembl:ENSMUST00000024860(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9QXY6|reactome:R-MMU-983231 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:COp4bL5nQo5RCRHYzQYqtdl4Xjo10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8VHK9 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9030648|uniprotkb:G3X8Y4|uniprotkb:Q6ZPP7|uniprotkb:Q9CSE8|ensembl:ENSMUSP00000029336 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dhx36_mouse(display_long)|uniprotkb:Dhx36(gene name)|psi-mi:Dhx36(display_short)|uniprotkb:Ddx36(gene name synonym)|uniprotkb:Kiaa1488(gene name synonym)|uniprotkb:Mlel1(gene name synonym)|uniprotkb:DEAH box protein 36(gene name synonym)|uniprotkb:MLE-like protein 1(gene name synonym)|uniprotkb:RNA helicase associated with AU-rich element ARE(gene name synonym)|uniprotkb:DEAD/H box polypeptide 36(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:XP_011238540.1|refseq:NP_082412.2|dip:DIP-48576N|ensembl:ENSMUSG00000027770(gene)|ensembl:ENSMUST00000029336(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001503"(ossification)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902064"(regulation of transcription from RNA polymerase II promoter involved in spermatogenesis)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:6UP2|rcsb pdb:6UP3|rcsb pdb:6UP4|reactome:R-MMU-3134963 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:P0657u4/yuv0IRfkUpvXuvlyzBE10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQS8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-646010|ensembl:ENSMUSP00000067681 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sc61b_mouse(display_long)|uniprotkb:Sec61b(gene name)|psi-mi:Sec61b(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_077133.1|ensembl:ENSMUSG00000053317(gene)|ensembl:ENSMUST00000065678(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:oYv4LR4IHW0y8CFM1qhPln1/NB410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R1Q7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-644894|uniprotkb:Q3U4I3|ensembl:ENSMUSP00000033486|ensembl:ENSMUSP00000132645 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:plp2_mouse(display_long)|uniprotkb:Plp2(gene name)|psi-mi:Plp2(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_062729.1|ensembl:ENSMUST00000071118(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019956"(chemokine binding)|interpro:IPR008253(Marvel)|ensembl:ENSMUSG00000031146(gene)|ensembl:ENSMUSG00000057762(gene)|ensembl:ENSMUST00000033486(transcript) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:qeo2iHgGYi7vTpfHycbLsnW6jks10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P63082 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-642254|uniprotkb:P23967|uniprotkb:Q3TD69|ensembl:ENSMUSP00000024932|ensembl:ENSMUSP00000111059 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:vatl_mouse(display_long)|uniprotkb:PL16(gene name synonym)|uniprotkb:Atp6v0c(gene name)|psi-mi:Atp6v0c(display_short)|uniprotkb:Atp6c(gene name synonym)|uniprotkb:Atp6l(gene name synonym)|uniprotkb:Atpl(gene name synonym)|uniprotkb:Mvp(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033859.1|ensembl:ENSMUSG00000024121(gene)|ensembl:ENSMUST00000024932(transcript)|ensembl:ENSMUST00000098862(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1904093"(negative regulation of autophagic cell death)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|reactome:R-MMU-1222556|reactome:R-MMU-6798695|reactome:R-MMU-77387|reactome:R-MMU-917977|reactome:R-MMU-9639288|reactome:R-MMU-983712|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain) - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:Qx4BtXXIXdTlTTWE3nBHM8kThHU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9QWF0 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-639217|uniprotkb:Q3TU22|uniprotkb:Q544M2|ensembl:ENSMUSP00000002914 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:caf1a_mouse(display_long)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym)|uniprotkb:Chaf1a(gene name)|psi-mi:Chaf1a(display_short)|uniprotkb:Caip150(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_038761.1|ensembl:ENSMUSG00000002835(gene)|ensembl:ENSMUST00000002914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|rcsb pdb:1S4Z - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:9RRlhyFihl5lllNaVK0bJDWlCRU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q3TUQ5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986929|ensembl:ENSMUSP00000021381 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:q3tuq5_mouse(display_long)|uniprotkb:Pnn(gene name)|psi-mi:Pnn(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000020994(gene)|ensembl:ENSMUST00000021381(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|refseq:NP_032917.2 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1PBjtcetMJdW1mOBqWRE0B6DZMc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P48379 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-3043952|ensembl:ENSMUSP00000002444|uniprotkb:Q8BXR3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:rfx2_mouse(display_long)|uniprotkb:Rfx2(gene name)|psi-mi:Rfx2(display_short)|uniprotkb:Regulatory factor X 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000024206(gene)|ensembl:ENSMUST00000002444(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001675"(acrosome assembly)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|refseq:NP_033082.1|refseq:NP_082063.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:1pdvERwU8gFjVZXQmwVm3HYiG0010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O88441 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-775894|ensembl:ENSMUSP00000028511|uniprotkb:Q3TFR2 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mtx2_mouse(display_long)|uniprotkb:Mtx2(gene name)|psi-mi:Mtx2(display_short)|uniprotkb:MNCb-0780(orf name)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000027099(gene)|ensembl:ENSMUST00000028511(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O88441|refseq:NP_058084.3 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:uODpL/j0VXAZ6jJINeggCV1nmLM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CH72 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-773837|uniprotkb:Q8K055|ensembl:ENSMUSP00000062277|ensembl:ENSMUSP00000102989 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tri32_mouse(display_long)|uniprotkb:Trim32(gene name)|psi-mi:Trim32(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001155254.1|refseq:NP_444314.2|refseq:XP_006538298.1|refseq:XP_006538299.1|refseq:XP_006538300.1|refseq:XP_006538301.1|ensembl:ENSMUSG00000051675(gene)|ensembl:ENSMUST00000050850(transcript)|ensembl:ENSMUST00000107366(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902173"(negative regulation of keratinocyte apoptotic process)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|reactome:R-MMU-3134975|reactome:R-MMU-983168 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:pVnRolpa1+rjaQPRjz6ldqpZS7M10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P59997 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986944|uniprotkb:Q3U1M5|uniprotkb:Q3UR56|uniprotkb:Q3V3Q1|uniprotkb:Q69ZT4 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:kdm2a_mouse(display_long)|uniprotkb:Kdm2a(gene name)|psi-mi:Kdm2a(display_short)|uniprotkb:Fbxl11(gene name synonym)|uniprotkb:Jhdm1a(gene name synonym)|uniprotkb:Kiaa1004(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:Fbl11(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 reactome:R-MMU-3214842|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|rcsb pdb:4QWN|rcsb pdb:4QX7|rcsb pdb:4QX8|rcsb pdb:4QXB|rcsb pdb:4QXC|rcsb pdb:4QXH|rcsb pdb:4TN7|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|refseq:NP_001001984.2|dip:DIP-46352N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:CNPg1cKesf1BShFGqK+KbakRtao10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P70280 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-6555653 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:vamp7_mouse(display_long)|uniprotkb:Vamp7(gene name)|psi-mi:Vamp7(display_short)|uniprotkb:Sybl1(gene name synonym)|uniprotkb:Synaptobrevin-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001289067.1|go:"GO:0031143"(pseudopodium)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0034197"(triglyceride transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:1900483"(regulation of protein targeting to vacuolar membrane)|go:"GO:1903595"(positive regulation of histamine secretion by mast cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|rcsb pdb:2VX8|rcsb pdb:4B93|rcsb pdb:4AFI|refseq:NP_035645.1|dip:DIP-46794N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:SiLCNUI3MPgJmnHFO9TWD4F4/fY10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q07813 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-700711|ensembl:ENSMUSP00000033093 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:bax_mouse(display_long)|uniprotkb:Bax(gene name)|psi-mi:Bax(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_031553.1|dip:DIP-29541N|ensembl:ENSMUSG00000003873(gene)|ensembl:ENSMUST00000033093(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001764"(neuron migration)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0001777"(T cell homeostatic proliferation)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001822"(kidney development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001844"(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0002358"(B cell homeostatic proliferation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007008"(outer mitochondrial membrane organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0009611"(response to wounding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009651"(response to salt stress)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015267"(channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032976"(release of matrix enzymes from mitochondria)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045136"(development of secondary sexual characteristics)|go:"GO:0045333"(cellular respiration)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048087"(positive regulation of developmental pigmentation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0048678"(response to axon injury)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051087"(chaperone binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051400"(BH domain binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060011"(Sertoli cell proliferation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071944"(cell periphery)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097144"(BAX complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1990117"(B cell receptor apoptotic signaling pathway)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026304|interpro:IPR036834|rcsb pdb:2XA0|rcsb pdb:5W62|reactome:R-MMU-111457|reactome:R-MMU-114294|reactome:R-MMU-5620971|reactome:R-MMU-6804114 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:tcxgXP9KAEZfEFruVYzgAojnIK010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9CQS5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4284935|uniprotkb:Q91XF3|ensembl:ENSMUSP00000024620 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:riok2_mouse(display_long)|uniprotkb:Riok2(gene name)|psi-mi:Riok2(display_short)|uniprotkb:RIO kinase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_080210.1|ensembl:ENSMUST00000024620(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000208"(positive regulation of ribosomal small subunit export from nucleus)|ensembl:ENSMUSG00000116564(gene)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015285(RIO2 kinase, winged helix, N-terminal)|interpro:IPR018935|interpro:IPR030484|interpro:IPR036388|interpro:IPR036390|reactome:R-MMU-6791226 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:bDp93jQ73Qy3/ZrL3sdSJgmkIik10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CFD4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987935|ensembl:ENSMUSP00000031539|uniprotkb:Q8BLI6|uniprotkb:Q8BUQ7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:snx8_mouse(display_long)|uniprotkb:Snx8(gene name)|psi-mi:Snx8(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000029560(gene)|ensembl:ENSMUST00000031539(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR028662|interpro:IPR035704|interpro:IPR036871|mint:Q8CFD4|go:"GO:0035091"(phosphatidylinositol binding)|refseq:NP_758481.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:lpEXla4dFEb9U1Du6tud2giVy5U10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q64331 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-776155 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:myo6_mouse(display_long)|uniprotkb:Myo6(gene name)|psi-mi:Myo6(display_short)|uniprotkb:Sv(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym)|uniprotkb:Protein twist(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR001609(Myosin head, motor region)|interpro:IPR032412|interpro:IPR027417|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR036114|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR036961|mint:Q64331|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006605"(protein targeting)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0016459"(myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048839"(inner ear development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051046"(regulation of secretion)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0098683"(cochlear hair cell ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:2KIA|rcsb pdb:2LD3|rcsb pdb:3H8D|rcsb pdb:5V6E|rcsb pdb:5V6H|reactome:R-MMU-190873|reactome:R-MMU-399719|reactome:R-MMU-9013418|reactome:R-MMU-9013420|reactome:R-MMU-9013422 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:RAUHi/cXk5cm3K/IP4SMrlLieek10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8CF66 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986803|ensembl:ENSMUSP00000056693|uniprotkb:B7ZN18|uniprotkb:Q8CEW4|uniprotkb:Q8CF77 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:ltor4_mouse(display_long)|uniprotkb:Lamtor4(gene name)|psi-mi:Lamtor4(display_short)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|interpro:IPR034601|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8943724|reactome:R-MMU-9639288|ensembl:ENSMUSG00000050552(gene)|ensembl:ENSMUST00000062067(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0008361"(regulation of cell size)|refseq:NP_001074577.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:2jliSuMlkXfxP5+TupZCPgP2FLc10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q2LKW6 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986823 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nl1b1_mouse(display_long)|uniprotkb:Nlrp1b(gene name)|psi-mi:Nlrp1b(display_short)|uniprotkb:Nalp1b(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR033516|interpro:IPR041075|interpro:IPR041267|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR032675|go:"GO:0030163"(protein catabolic process)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0043621"(protein self-association)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072558"(NLRP1 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904784"(NLRP1 inflammasome complex assembly)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:WNGijvOpM1nLrpW6fNxaqYbdj2I10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O09005 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987057|ensembl:ENSMUSP00000048519|uniprotkb:Q8R4H3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:degs1_mouse(display_long)|uniprotkb:Degs1(gene name)|psi-mi:Degs1(display_short)|uniprotkb:Degs(gene name synonym)|uniprotkb:Des1(gene name synonym)|uniprotkb:Mdes(gene name synonym)|uniprotkb:Degenerative spermatocyte homolog 1(gene name synonym)|uniprotkb:Dihydroceramide desaturase-1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000038633(gene)|ensembl:ENSMUST00000035295(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042284"(sphingolipid delta-4 desaturase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043217"(myelin maintenance)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050251"(retinol isomerase activity)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR011388(Sphingolipid delta4-desaturase)|interpro:IPR013866(Sphingolipid delta4-desaturase, N-terminal)|interpro:IPR031196|reactome:R-MMU-1660661|reactome:R-MMU-6798695|go:"GO:0005739"(mitochondrion)|refseq:NP_031879.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:rM24ovYi+3Gtl3lPh3NKfL7/S6M10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P60766 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-81763|ensembl:ENSMUSP00000054634|uniprotkb:A2A9U6|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q3THZ7|uniprotkb:Q3TJK6|uniprotkb:Q545V0|uniprotkb:Q6P201|uniprotkb:Q8BQ51 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cdc42_mouse(display_long)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000006699(gene)|ensembl:ENSMUST00000051477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|refseq:NP_033991.1|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043209"(myelin sheath)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051647"(nucleus localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071944"(cell periphery)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60766|rcsb pdb:3EG5|rcsb pdb:5C2J|reactome:R-MMU-114604|reactome:R-MMU-182971|reactome:R-MMU-2029482|reactome:R-MMU-389359|reactome:R-MMU-3928662|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-525793|reactome:R-MMU-5625970|reactome:R-MMU-5626467|reactome:R-MMU-5627123|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-983231|go:"GO:0048664"(neuron fate determination)|refseq:NP_001230698.1|dip:DIP-32554N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R1A4 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-776274|uniprotkb:Q45V78|uniprotkb:Q5PRE6|uniprotkb:Q6PJ17|uniprotkb:Q9CSB6|uniprotkb:Q9CXM7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:dock7_mouse(display_long)|uniprotkb:Gm430(gene name synonym)|uniprotkb:Dock7(gene name)|psi-mi:Dock7(display_short)|uniprotkb:Kiaa1771(gene name synonym)|uniprotkb:Mnlt(gene name synonym)|uniprotkb:Protein moonlight(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR027357|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR043162|interpro:IPR043161|interpro:IPR026791|interpro:IPR027007|interpro:IPR035892|interpro:IPR037808|mint:Q8R1A4|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043473"(pigmentation)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|reactome:R-MMU-8875555|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-983231 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:T4W30iJF8XaTuK57c9vlJFr9gpg10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9Z2P8 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987011|ensembl:ENSMUSP00000073852|ensembl:ENSMUSP00000098843 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:vamp5_mouse(display_long)|uniprotkb:Vamp5(gene name)|psi-mi:Vamp5(display_short)|uniprotkb:Myobrevin(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000073002(gene)|ensembl:ENSMUST00000074231(transcript)|ensembl:ENSMUST00000101285(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042166|interpro:IPR042581|interpro:IPR042855|go:"GO:0031301"(integral component of organelle membrane)|refseq:NP_001074211.1|refseq:NP_058568.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:VHXBOMwhAqIpHfq/4wpnHQZdBe010090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q2YDW2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987104|uniprotkb:Q3TJ50|uniprotkb:Q3TLZ1|uniprotkb:Q3TQV9|uniprotkb:Q922H6 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:msto1_mouse(display_long)|uniprotkb:Msto1(gene name)|psi-mi:Msto1(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0005737"(cytoplasm)|interpro:IPR029209|interpro:IPR019605|refseq:NP_659147.2|interpro:IPR036525 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:KzmbhThjvtd2SFV3GUKMSt9RPRw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P50220 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9D1C2 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987080|ensembl:ENSMUSP00000023064 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:cby1_mouse(display_long)|uniprotkb:Cby1(gene name)|psi-mi:Cby1(display_short)|uniprotkb:Cby(gene name synonym)|uniprotkb:Pgea1(gene name synonym)|uniprotkb:Cytosolic leucine-rich protein(gene name synonym)|uniprotkb:PIGEA-14(gene name synonym)|uniprotkb:PKD2 interactor, Golgi and endoplasmic reticulum-associated 1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000022428(gene)|ensembl:ENSMUST00000023064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005814"(centriole)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008104"(protein localization)|go:"GO:0016607"(nuclear speck)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0033504"(floor plate development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR028118|reactome:R-MMU-3769402|refseq:NP_082910.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:6XCwnxgqmH0hfUZtBNCVKPIpC/Y10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P11103 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:O35988 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986850|ensembl:ENSMUSP00000017153 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:sdc4_mouse(display_long)|uniprotkb:Sdc4(gene name)|psi-mi:Sdc4(display_short)|uniprotkb:Ryudocan core protein(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:0045121"(membrane raft)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|reactome:R-MMU-1971475|go:"GO:0045860"(positive regulation of protein kinase activity)|reactome:R-MMU-2022928|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0070053"(thrombospondin receptor activity)|reactome:R-MMU-2024096|reactome:R-MMU-202733|reactome:R-MMU-3000170|reactome:R-MMU-975634|ensembl:ENSMUSG00000017009(gene)|ensembl:ENSMUST00000017153(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|refseq:NP_035651.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:O8ZQM+ystmX927MWsVaoV51rH2w10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8BGZ7 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9986780|ensembl:ENSMUSP00000036246|uniprotkb:B2RQH6 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:k2c75_mouse(display_long)|uniprotkb:Krt75(gene name)|psi-mi:Krt75(display_short)|uniprotkb:Kb18(gene name synonym)|uniprotkb:Cytokeratin-75(gene name synonym)|uniprotkb:Keratin-6 hair follicle(gene name synonym)|uniprotkb:Keratin-75(gene name synonym)|uniprotkb:Type II keratin-K6hf(gene name synonym)|uniprotkb:Type-II keratin Kb18(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000022986(gene)|ensembl:ENSMUST00000042957(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005882"(intermediate filament)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_579935.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:cfwgts4zv82rWZpRAVppU+VAZsQ10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:A6ZI44 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-4283485|ensembl:ENSMUSP00000084846 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:a6zi44_mouse(display_long)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_001170778.1|refseq:XP_006507272.1|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000087566(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035094"(response to nicotine)|go:"GO:0043627"(response to estrogen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:QfjcGwfzA6vJ+Ip6oyWZf4ZCtQM10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q8R404 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-9987001|ensembl:ENSMUSP00000052908 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:mic13_mouse(display_long)|uniprotkb:Micos13(gene name)|psi-mi:Micos13(display_short)|uniprotkb:Mic13(gene name synonym)|uniprotkb:Qil1(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 ensembl:ENSMUSG00000049760(gene)|ensembl:ENSMUST00000052832(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0044284"(mitochondrial crista junction)|go:"GO:0061617"(MICOS complex)|interpro:IPR026769|mint:Q8R404|refseq:NP_694792.1 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:sHMTm3mMJ4awh6B8mJEoa24WO0A10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:P63028 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1635228|uniprotkb:P14701|uniprotkb:Q3TMT0|uniprotkb:Q3TWS8|uniprotkb:Q3TWX0|uniprotkb:Q3UAG7|uniprotkb:Q569M9|ensembl:ENSMUSP00000106519 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:tctp_mouse(display_long)|uniprotkb:Tpt1(gene name)|psi-mi:Tpt1(display_short)|uniprotkb:Trt(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:21 kDa polypeptide(gene name synonym)|uniprotkb:p21(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_033455.1|ensembl:ENSMUSG00000060126(gene)|ensembl:ENSMUST00000110894(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|mint:P63028|rcsb pdb:5O9K - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:4STBIjAMhg84kMGx/MP1PUh6g4g10090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9DBP5 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-1635267|uniprotkb:Q8BK17|uniprotkb:Q8VD05|uniprotkb:Q9DCS7 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:kcy_mouse(display_long)|uniprotkb:Cmpk1(gene name)|psi-mi:Cmpk1(display_short)|uniprotkb:Cmk(gene name synonym)|uniprotkb:Uck(gene name synonym)|uniprotkb:Umk(gene name synonym)|uniprotkb:Umpk(gene name synonym)|uniprotkb:Cmpk(gene name synonym)|uniprotkb:Deoxycytidylate kinase(gene name synonym)|uniprotkb:Uridine monophosphate/cytidine monophosphate kinase(gene name synonym)|uniprotkb:Nucleoside-diphosphate kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 interpro:IPR033690|refseq:NP_079923.3|interpro:IPR000850(Adenylate kinase)|interpro:IPR006266(UMP-CMP kinase)|interpro:IPR027417|mint:Q9DBP5|go:"GO:0004127"(cytidylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006225"(UDP biosynthetic process)|go:"GO:0006227"(dUDP biosynthetic process)|go:"GO:0006240"(dCDP biosynthetic process)|go:"GO:0009041"(uridylate kinase activity)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0036430"(CMP kinase activity)|go:"GO:0036431"(dCMP kinase activity)|go:"GO:0046705"(CDP biosynthetic process)|reactome:R-MMU-499943 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:I1hyl+mlW2kp29eULytDWnH/Fj410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52927 uniprotkb:Q9R1P1 intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556 intact:EBI-991734|ensembl:ENSMUSP00000099436 psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym) psi-mi:psb3_mouse(display_long)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym)|uniprotkb:Psmb3(gene name)|psi-mi:Psmb3(display_short) psi-mi:"MI:0096"(pull down) Singh et al. (2015) imex:IM-23312|pubmed:26045162 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9986179|imex:IM-23312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584 refseq:NP_036101.1|ensembl:ENSMUSG00000069744(gene)|ensembl:ENSMUST00000103147(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-8939902 - - - figure legend:"\"A\""|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-mle12)|taxid:10090(Mus musculus) - 2014/11/25 2018/07/05 rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090 rogid:LLhBgxXML1O4gyh9co1+55VyPM410090 intact-crc:30F6DE97DBE48625|rigid:/qgjcEl0y2PAG01liyEcwgIoCGw false myc tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)